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E34

Euk-Vir

Murid_betaherpesvirus_8

E34__YP_007016438__Murid_betaherpesvirus_8__1261657

Identity

Accession:
YP_007016438 ↗
Protein ID:
E34
Kingdom:
euk

Quality

56.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 177-189_313-406
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25722.2 best CMV_UL34 117.4 1.10e-33 80.4% 34.2%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3jckC00 1.25.40.570 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 43.0 2.94e-01 80.4% 41.3%
2p9bA04 1.20.58.520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Amidohydrolase 0.55 35.0 3.73e-01 70.1% 73.9%
3fr3B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.52 36.0 3.53e-01 71.0% 87.0%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3874750 101.1.1.249 alpha arrays › HTH › HTH › Three-helical HTH › SGIII 0.50 32.0 3.61e-01 80.4% 86.3%
D2 medium residues 190-312
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25722.2 best CMV_UL34 156.9 9.30e-46 100.0% 51.3%
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 44.0 5.60e-01 83.7% 100.0%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 51.0 4.52e-01 74.8% 76.8%
1lb3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 54.0 4.82e-01 82.9% 88.0%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 51.0 4.69e-01 78.9% 92.5%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.67 51.0 5.39e-01 78.0% 99.1%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 52.0 4.74e-01 80.5% 94.3%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.67 59.0 5.39e-01 96.7% 78.2%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.66 46.0 4.85e-01 82.1% 78.1%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.65 58.0 4.81e-01 96.7% 77.8%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 50.0 4.66e-01 81.3% 98.0%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 49.0 4.56e-01 81.3% 100.0%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.64 56.0 4.77e-01 95.9% 94.5%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.62 46.0 4.72e-01 77.2% 96.6%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.62 47.0 4.85e-01 79.7% 89.7%
3cf6E03 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.62 49.0 4.86e-01 92.7% 78.6%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.62 40.0 4.05e-01 71.5% 65.3%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 52.0 4.61e-01 90.2% 72.0%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 49.0 4.71e-01 83.7% 95.7%
3vw7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 51.0 3.85e-01 88.6% 49.6%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 50.0 4.70e-01 89.4% 81.6%
1w07A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 50.0 4.52e-01 90.2% 83.3%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.59 41.0 4.24e-01 77.2% 77.0%
1ivhA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 49.0 4.69e-01 89.4% 86.5%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 47.0 4.58e-01 87.0% 100.0%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.58 43.0 4.36e-01 82.1% 79.0%
4x28A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 49.0 4.48e-01 91.1% 83.9%
5l0wB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 38.0 3.65e-01 91.9% 57.2%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 48.0 4.34e-01 91.1% 89.5%
5iduC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 47.0 4.37e-01 89.4% 76.7%
2pg0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 48.0 4.48e-01 89.4% 81.9%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.57 49.0 4.50e-01 95.1% 92.6%
1egdA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 48.0 4.62e-01 91.9% 88.7%
1gu9C00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.56 35.0 3.21e-01 95.1% 45.2%
7ymiD01 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.56 45.0 3.97e-01 86.2% 79.4%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 42.0 3.97e-01 87.0% 66.0%
6k41R00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 46.0 3.70e-01 90.2% 46.9%
1wtyA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.55 39.0 4.04e-01 96.7% 77.6%
7d1tA01 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.54 47.0 4.11e-01 93.5% 83.0%
5iduA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.54 42.0 4.28e-01 90.2% 84.2%
4ip8A00 1.10.132.110 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein 0.54 35.0 3.77e-01 85.4% 76.2%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 45.0 3.97e-01 91.1% 92.7%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 39.0 3.76e-01 88.6% 68.9%
4dyqA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.51 35.0 3.74e-01 92.7% 83.5%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5001809 1075.1.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 0.70 60.0 4.89e-01 91.9% 92.7%
4977418 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.67 45.0 4.78e-01 76.4% 77.3%
4433661 3651.1.1.0 alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain 0.66 42.0 4.20e-01 80.5% 61.6%
3260973 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 53.0 5.61e-01 84.6% 93.6%
3601072 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.65 48.0 4.65e-01 90.2% 67.9%
54292 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.65 46.0 4.81e-01 83.7% 79.1%
3783653 632.1.1.22 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › FKS1_dom2 0.64 50.0 4.92e-01 91.1% 76.9%
3977220 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.64 57.0 4.43e-01 95.9% 71.9%
4951650 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.64 56.0 4.36e-01 95.9% 71.7%
5013803 3843.1.1.4 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB 0.63 43.0 4.35e-01 89.4% 68.8%
1019365 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.62 47.0 4.88e-01 79.7% 91.3%
3612957 109.21.1.0 alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain 0.62 49.0 3.02e-01 82.1% 18.1%
4843090 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.62 44.0 4.65e-01 74.8% 98.2%
3533245 192.15.1.2 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Mod_r 0.61 34.0 3.14e-01 70.7% 41.9%
3250178 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 47.0 4.36e-01 81.3% 72.3%
3638102 1174.1.1.2 alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 › LtrA 0.60 52.0 4.51e-01 91.9% 79.5%
2970012 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.60 44.0 3.87e-01 75.6% 52.0%
4936312 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.60 46.0 4.83e-01 81.3% 97.3%
4011838 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.60 50.0 3.86e-01 89.4% 47.0%
3467233 109.3.1.2 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 0.60 48.0 3.54e-01 87.0% 32.5%
4015786 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.60 50.0 3.83e-01 89.4% 42.9%
4980864 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.60 45.0 4.52e-01 78.0% 84.6%
3402374 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 47.0 4.57e-01 87.0% 77.0%
3723152 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.58 53.0 3.70e-01 100.0% 35.5%
3290528 109.3.1.379 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4153 0.58 49.0 4.09e-01 94.3% 56.4%
4160603 3636.1.1.0 a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain 0.58 48.0 4.27e-01 89.4% 70.9%
3799 603.6.1.1 alpha bundles › STAT-like › MukF C-terminal domain-like › MukF C-terminal domain-like › MukF_M 0.57 49.0 4.50e-01 95.1% 92.6%
3689336 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 50.0 4.31e-01 97.6% 61.0%
3934654 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.57 44.0 3.91e-01 82.1% 84.4%
4133095 601.2.1.1 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › 7tm_1 0.56 45.0 4.53e-01 96.7% 84.0%
3937526 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.56 48.0 4.58e-01 91.9% 80.0%
3237985 150.1.1.24 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Prominin 0.56 43.0 3.42e-01 81.3% 48.2%
3615158 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.56 48.0 4.45e-01 92.7% 76.8%
4989849 5069.1.2.1 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Respiratory nitrate reductase 1 gamma chain › Nitrate_red_gam 0.55 45.0 3.62e-01 87.8% 46.9%
3203534 192.15.1.139 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Cation_efflux 0.55 42.0 3.76e-01 95.9% 57.1%
3671005 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.54 37.0 3.67e-01 76.4% 64.4%
3443494 7015.1.1.1 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC 0.54 45.0 3.94e-01 91.9% 75.8%
3444845 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.53 44.0 3.84e-01 90.2% 85.8%
3179630 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.53 49.0 3.77e-01 100.0% 64.2%
3994910 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.53 45.0 4.21e-01 91.9% 82.0%
3539619 7015.1.1.1 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC 0.53 42.0 3.95e-01 89.4% 70.0%
3973161 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.53 44.0 3.68e-01 89.4% 52.4%