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E4_ORF2

Euk-Vir

Bottlenose_dolphin_adenovirus_1

E4_ORF2__YP_009704143__Bottlenose_dolphin_adenovirus_1__1714377

Identity

Accession:
YP_009704143 ↗
Protein ID:
E4_ORF2
Kingdom:
euk

Quality

66.3 mean pLDDT

Taxonomy

Bamfordvirae› Preplasmiviricota› Pharingeaviricetes› Rowavirales› Adenoviridae› Mastadenovirus› Bottlenose_dolphin_adenovirus_1

TaxID: 1714377

Cluster

View cluster (63 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 9-77
PDB
Domain cluster: representative
CATH (76)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.80 60.0 5.02e-01 100.0% 47.4%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.77 66.0 5.52e-01 100.0% 55.9%
1sqhA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.74 51.0 3.80e-01 95.7% 29.5%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.74 61.0 5.71e-01 100.0% 72.9%
3c6kB03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.74 55.0 3.99e-01 95.7% 29.4%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.73 65.0 5.59e-01 100.0% 63.0%
4ushA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 50.0 4.35e-01 100.0% 48.5%
2khdA00 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 54.0 4.65e-01 100.0% 52.8%
2ek0A00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.70 56.0 5.12e-01 94.2% 66.7%
7o4xA01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 51.0 4.52e-01 100.0% 55.6%
1o51A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 53.0 4.86e-01 100.0% 65.2%
3njcA00 3.30.1380.20 Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 0.68 57.0 4.40e-01 95.7% 41.8%
2nrqA00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.68 55.0 4.42e-01 100.0% 45.3%
4g2uA00 3.40.33.10 Alpha Beta › 3-Layer(aba) Sandwich › Pathogenesis-related Protein p14a › CAP 0.67 61.0 4.27e-01 100.0% 41.4%
2ql8A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.66 49.0 3.99e-01 81.2% 72.1%
1y0hB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 50.0 4.53e-01 100.0% 58.2%
5b08A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 54.0 4.81e-01 100.0% 65.0%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 48.0 4.41e-01 100.0% 60.0%
2onfA01 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.64 47.0 3.83e-01 78.3% 75.4%
2ogkD00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.64 53.0 4.19e-01 100.0% 44.4%
3ce8A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 47.0 4.35e-01 100.0% 60.7%
3duwA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 51.0 3.62e-01 92.8% 27.9%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 49.0 4.28e-01 100.0% 55.1%
3m05B01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 44.0 4.05e-01 100.0% 55.4%
3ue2A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.63 52.0 4.84e-01 100.0% 73.9%
3go9A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 54.0 3.87e-01 100.0% 35.5%
1sqeA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 49.0 4.41e-01 100.0% 61.4%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 48.0 4.22e-01 100.0% 56.1%
1p1lA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 47.0 4.23e-01 100.0% 57.8%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 42.0 4.15e-01 100.0% 67.6%
3e23A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 52.0 3.72e-01 95.7% 32.8%
1jw3A00 3.55.10.10 Alpha Beta › 3-Layer(bab) Sandwich › Archease, Possible Chaperone; Chain: A; domain 1 › Archease domain 0.61 45.0 3.70e-01 97.1% 40.7%
2f9aA01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.60 51.0 3.25e-01 100.0% 80.0%
2od6C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 51.0 4.47e-01 100.0% 62.6%
3o4oB03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 50.0 4.37e-01 100.0% 58.7%
3gk6A00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.60 51.0 4.09e-01 100.0% 45.8%
7wa9A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.60 52.0 4.22e-01 100.0% 85.1%
4mh4A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.60 46.0 4.25e-01 85.5% 71.3%
3pxpA02 3.30.450.180 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.60 52.0 3.82e-01 100.0% 81.9%
2ab5B01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.59 45.0 3.74e-01 100.0% 45.3%
1tedA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.59 50.0 3.89e-01 94.2% 92.6%
1twfB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.59 50.0 4.19e-01 97.1% 84.7%
4za1C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 44.0 4.03e-01 98.6% 60.9%
1vq0A01 3.55.30.10 Alpha Beta › 3-Layer(bab) Sandwich › Hsp33 domain › Hsp33 domain 0.59 49.0 3.47e-01 95.7% 70.4%
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.58 52.0 3.65e-01 98.6% 73.6%
6v04A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.58 50.0 4.20e-01 100.0% 82.7%
6n2nA01 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.58 43.0 3.28e-01 94.2% 32.0%
2vqeC02 3.30.1140.32 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Ribosomal protein S3, C-terminal domain 0.58 48.0 4.34e-01 95.7% 93.0%
1hw7A01 3.55.30.10 Alpha Beta › 3-Layer(bab) Sandwich › Hsp33 domain › Hsp33 domain 0.58 49.0 3.73e-01 97.1% 91.3%
3jamD02 3.30.1140.32 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Ribosomal protein S3, C-terminal domain 0.57 51.0 4.11e-01 100.0% 74.4%
4r6uA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 51.0 4.46e-01 100.0% 73.8%
5u1xA02 2.60.490.10 Mainly Beta › Sandwich › atp-gated p2x4 ion channel fold › atp-gated p2x4 ion channel domain 0.57 47.0 3.19e-01 94.2% 75.6%
1s67L00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 47.0 3.98e-01 94.2% 87.4%
1t0tV02 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.56 45.0 3.99e-01 100.0% 58.6%
2raaA00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.56 49.0 3.63e-01 98.6% 76.4%
3bp6B02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 50.0 4.59e-01 100.0% 77.3%
2afsA00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.55 46.0 3.03e-01 95.7% 84.5%
4hh2B03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.55 46.0 4.13e-01 94.2% 99.0%
3u83A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 49.0 4.34e-01 100.0% 75.2%
2oojA00 2.40.350.10 Mainly Beta › Beta Barrel › AOC barrel-like › SO1590-like 0.55 45.0 3.76e-01 95.7% 97.7%
1z94B00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 46.0 3.77e-01 100.0% 83.9%
1d06A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.54 46.0 3.73e-01 94.2% 80.0%
4gf3A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.54 38.0 3.31e-01 100.0% 43.9%
1cx8A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.54 45.0 3.00e-01 95.7% 83.1%
3oh8A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 45.0 3.71e-01 100.0% 82.1%
3w1hA01 3.90.1150.110 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.53 44.0 3.34e-01 98.6% 60.3%
3ks7A02 2.60.120.230 Mainly Beta › Sandwich › Jelly Rolls › 0.53 46.0 3.47e-01 100.0% 78.2%
4bfeA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 45.0 4.26e-01 100.0% 80.2%
4ctaA02 3.30.70.2860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 36.0 3.56e-01 98.6% 66.7%
3oloA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.52 42.0 3.70e-01 92.8% 84.7%
3ga7A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 41.0 2.77e-01 91.3% 91.6%
3mjqA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.52 44.0 3.86e-01 97.1% 92.5%
7kznP01 3.30.740.10 Alpha Beta › 2-Layer Sandwich › Protein Inhibitor Of Neuronal Nitric Oxide Synthase › Protein Inhibitor Of Neuronal Nitric Oxide Synthase; 0.51 40.0 3.72e-01 89.9% 83.9%
3q6aB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 44.0 3.61e-01 100.0% 75.4%
5a2fA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 42.0 3.73e-01 100.0% 77.7%
3o3uN03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.50 42.0 3.72e-01 100.0% 78.4%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1146572 304.152.1.1 ↗ a+b two layers › Alpha-beta plaits › E4-ORF3 › E4-ORF3 › Adeno_E4_ORF3 0.77 66.0 5.55e-01 100.0% 56.9%
5000388 304.44.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 0.74 55.0 5.01e-01 100.0% 60.0%
3479702 304.44.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 0.74 59.0 5.07e-01 100.0% 56.2%
3985634 3313.1.1.1 ↗ a+b two layers › Uncharacterized protein VC_A0919 › Uncharacterized protein VC_A0919 › Uncharacterized protein VC_A0919 › DUF406 0.74 62.0 5.39e-01 100.0% 62.0%
3190328 328.1.1.3 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like › Rpp20 0.72 48.0 4.31e-01 89.9% 50.5%
5022418 304.5.1.7 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 0.71 47.0 4.89e-01 100.0% 73.8%
5074889 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.71 63.0 5.69e-01 100.0% 81.1%
4941817 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.70 63.0 5.35e-01 100.0% 62.4%
3163632 3313.1.1.1 ↗ a+b two layers › Uncharacterized protein VC_A0919 › Uncharacterized protein VC_A0919 › Uncharacterized protein VC_A0919 › DUF406 0.70 57.0 5.42e-01 100.0% 76.2%
3165967 3313.1.1.1 ↗ a+b two layers › Uncharacterized protein VC_A0919 › Uncharacterized protein VC_A0919 › Uncharacterized protein VC_A0919 › DUF406 0.70 57.0 5.21e-01 100.0% 67.8%
3965385 304.14.1.1 ↗ a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.70 52.0 5.18e-01 100.0% 77.1%
4255094 304.28.1.35 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Amnionless 0.70 57.0 4.89e-01 100.0% 56.4%
3471357 304.133.1.0 ↗ a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein 0.70 62.0 5.16e-01 100.0% 82.5%
3929061 4955.1.1.0 ↗ a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.70 62.0 5.54e-01 100.0% 71.6%
3499933 273.1.1.0 ↗ a+b three layers › PR-1-like › PR-1-like › PR-1-like 0.69 52.0 4.25e-01 95.7% 43.1%
3600809 328.1.1.0 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like 0.69 55.0 4.15e-01 94.2% 36.4%
4538961 304.14.1.1 ↗ a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR 0.68 57.0 5.62e-01 100.0% 85.3%
5043596 304.15.1.0 ↗ a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.68 58.0 4.91e-01 100.0% 57.4%
4503821 304.12.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.67 52.0 5.23e-01 100.0% 84.3%
4400469 101.1.2.841 ↗ alpha arrays › HTH › HTH › winged helix domain › PF27221 0.67 56.0 4.31e-01 94.2% 40.5%
4233442 304.4.1.54 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Amnionless 0.67 59.0 4.95e-01 100.0% 57.5%
3518340 2004.1.3.2 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR,EKR 0.66 48.0 3.26e-01 76.8% 25.2%
4538250 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.65 54.0 4.31e-01 100.0% 45.9%
4935371 327.11.2.87 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › FLAD1_M 0.65 47.0 4.74e-01 98.6% 77.1%
4058190 301.8.1.1 ↗ a+b three layers › Bacillus chorismate mutase-like › 4'-phosphopantetheinyl transferase › 4'-phosphopantetheinyl transferase › ACPS 0.65 55.0 4.51e-01 95.7% 96.9%
5005033 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.65 48.0 4.66e-01 100.0% 71.2%
5062595 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.65 47.0 3.15e-01 76.8% 24.2%
4027274 273.1.1.2 ↗ a+b three layers › PR-1-like › PR-1-like › PR-1-like › CEP76_C 0.64 53.0 4.22e-01 92.8% 76.6%
5073850 304.43.1.6 ↗ a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 › FLAD1_M 0.64 51.0 4.97e-01 100.0% 80.0%
4976516 304.19.1.0 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain 0.64 48.0 4.51e-01 100.0% 64.4%
5061301 11.1.1.103 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CARDB 0.64 53.0 3.61e-01 98.6% 25.8%
4629521 304.5.1.3 ↗ a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.64 50.0 4.38e-01 100.0% 56.7%
3839261 310.3.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.64 45.0 3.79e-01 97.1% 42.9%
5051275 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.64 43.0 4.21e-01 100.0% 64.0%
3706456 304.55.2.8 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons 0.63 54.0 5.01e-01 100.0% 74.4%
4950106 312.1.1.0 ↗ a+b three layers › HIT-like › HIT-related › HIT-related 0.63 57.0 4.26e-01 100.0% 45.9%
5030500 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.63 49.0 3.98e-01 100.0% 42.9%
4016271 246.3.1.0 ↗ a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like 0.63 47.0 4.37e-01 95.7% 63.3%
3652417 2003.1.5.115 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_29 0.62 43.0 3.41e-01 97.1% 33.8%
3931669 304.4.1.54 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Amnionless 0.61 54.0 4.24e-01 100.0% 46.7%
4085595 301.8.1.1 ↗ a+b three layers › Bacillus chorismate mutase-like › 4'-phosphopantetheinyl transferase › 4'-phosphopantetheinyl transferase › ACPS 0.61 51.0 4.16e-01 94.2% 99.3%
5068347 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.61 54.0 3.99e-01 98.6% 79.4%
4668047 273.1.1.5 ↗ a+b three layers › PR-1-like › PR-1-like › PR-1-like › PF29714 0.60 50.0 4.20e-01 92.8% 56.7%
4230728 304.4.1.70 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › PF29828 0.60 52.0 4.32e-01 100.0% 78.5%
3519213 109.4.1.2122 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle, ZW10_C2 0.60 44.0 2.58e-01 78.3% 11.6%
3707944 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 51.0 4.33e-01 100.0% 66.4%
4016024 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.60 53.0 3.73e-01 98.6% 71.9%
3783737 2004.1.3.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.60 53.0 3.60e-01 100.0% 61.6%
5082567 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.60 53.0 3.83e-01 98.6% 81.6%
4616084 864.1.1.2 ↗ a+b two layers › DLC › DLC › DLC › Tctex-1 0.59 50.0 4.32e-01 94.2% 93.6%
4189854 2004.1.3.2 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR,EKR 0.59 53.0 3.51e-01 98.6% 57.8%
3598322 2487.1.1.0 ↗ a/b three-layered sandwiches › "The ""swivelling"" beta/beta/alpha domains" › "The ""swivelling"" beta/beta/alpha domain" › "The ""swivelling"" beta/beta/alpha domain" 0.59 48.0 3.84e-01 89.9% 100.0%
3211894 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 51.0 4.50e-01 100.0% 66.0%
3636462 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.59 52.0 3.66e-01 98.6% 68.2%
4932903 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.59 52.0 3.72e-01 98.6% 79.5%
4317100 230.2.1.2 ↗ a+b two layers › T-fold › Ribosomal protein S3-C › Ribosomal protein S3-C › VAR1 0.59 48.0 4.10e-01 92.8% 97.4%
5052583 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.59 46.0 4.10e-01 100.0% 59.0%
5068735 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.58 52.0 3.66e-01 100.0% 96.7%
4980833 2004.1.3.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.58 51.0 3.50e-01 98.6% 62.0%
5074033 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.58 51.0 3.67e-01 98.6% 79.4%
4067682 848.1.1.1 ↗ a+b complex topology › Hsp33 domain › Hsp33 domain › Hsp33 domain › HSP33 0.58 51.0 3.58e-01 100.0% 89.3%
4194439 848.1.1.1 ↗ a+b complex topology › Hsp33 domain › Hsp33 domain › Hsp33 domain › HSP33 0.58 50.0 3.51e-01 100.0% 87.7%
5026575 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.57 49.0 3.58e-01 94.2% 81.1%
4971652 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.57 51.0 3.67e-01 100.0% 77.9%
5048915 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.56 50.0 3.61e-01 98.6% 81.1%
5035578 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.56 50.0 3.53e-01 98.6% 75.7%
3907714 2011.1.1.8 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M28 0.56 48.0 3.09e-01 95.7% 82.7%
3786241 864.1.1.2 ↗ a+b two layers › DLC › DLC › DLC › Tctex-1 0.56 46.0 4.13e-01 94.2% 96.1%
5006044 206.1.1.268 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF6206 0.56 47.0 3.22e-01 100.0% 38.6%
4977581 223.1.1.0 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains 0.55 46.0 3.96e-01 94.2% 89.6%
5082316 101.1.2.187 ↗ alpha arrays › HTH › HTH › winged helix domain › Rep3_C 0.55 46.0 4.17e-01 92.8% 69.5%
3811740 2003.1.5.14 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3 0.55 44.0 3.12e-01 95.7% 25.7%
3931635 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.55 48.0 4.69e-01 98.6% 98.7%
4980612 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.55 49.0 4.72e-01 100.0% 93.8%
5073045 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.55 48.0 3.42e-01 98.6% 81.0%
3822140 387.1.5.7 ↗ few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like › SCRL 0.54 43.0 4.34e-01 91.3% 85.7%
3249790 4081.1.1.2 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › VIT 0.54 47.0 3.29e-01 100.0% 32.2%
3879806 864.1.1.0 ↗ a+b two layers › DLC › DLC › DLC 0.53 45.0 4.13e-01 94.2% 94.4%
3929637 382.1.1.23 ↗ few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › PF29371 0.53 49.0 3.85e-01 100.0% 73.1%
3412939 5001.1.1.41 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.52 43.0 2.84e-01 100.0% 77.5%
1954209 2004.1.1.44 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PRK 0.52 45.0 2.92e-01 97.1% 28.4%
3500427 3914.1.1.2 ↗ alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer 0.51 43.0 2.44e-01 92.8% 67.1%
D2 medium residues 78-131
PDB