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E4_ORF5

Euk-Vir

Bat_mastadenovirus_WIV11

E4_ORF5__YP_009246442__Bat_mastadenovirus_WIV11__1788433

Identity

Accession:
YP_009246442 ↗
Protein ID:
E4_ORF5
Kingdom:
euk

Quality

88.8 mean pLDDT

Taxonomy

Bamfordvirae› Preplasmiviricota› Pharingeaviricetes› Rowavirales› Adenoviridae› Mastadenovirus› Bat_mastadenovirus_WIV11

TaxID: 1788433

Cluster

View cluster (19 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 15-109
PDB
Domain cluster: representative
CATH (72)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.85 79.0 5.99e-01 100.0% 87.1%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 60.0 5.91e-01 74.7% 73.0%
3dbyL00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.83 74.0 5.30e-01 96.8% 36.2%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.82 72.0 6.19e-01 92.6% 87.1%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.82 57.0 6.23e-01 74.7% 88.3%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.81 74.0 5.67e-01 100.0% 86.6%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 42.0 5.27e-01 73.7% 83.3%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.79 62.0 5.80e-01 89.5% 68.7%
1yjgA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.79 73.0 6.10e-01 100.0% 68.2%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.79 72.0 5.52e-01 100.0% 50.7%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.79 56.0 5.59e-01 73.7% 71.4%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.79 64.0 6.66e-01 93.7% 94.3%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.78 65.0 6.00e-01 96.8% 70.8%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 51.0 6.04e-01 72.6% 100.0%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.77 71.0 5.86e-01 100.0% 65.6%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.77 67.0 5.65e-01 92.6% 93.4%
2fonA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 62.0 5.58e-01 85.3% 73.6%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 66.0 5.63e-01 93.7% 65.1%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.77 71.0 5.87e-01 100.0% 63.0%
2e87A01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.77 69.0 5.82e-01 100.0% 72.5%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 70.0 5.55e-01 100.0% 91.5%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 52.0 5.14e-01 70.5% 68.6%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.76 65.0 5.79e-01 96.8% 66.2%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 54.0 4.95e-01 73.7% 72.1%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.75 66.0 6.14e-01 95.8% 83.9%
3x29A00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.74 68.0 5.60e-01 100.0% 76.5%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 67.0 4.88e-01 100.0% 73.0%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.74 65.0 6.25e-01 100.0% 85.0%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 65.0 5.94e-01 94.7% 93.4%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.74 67.0 5.70e-01 100.0% 64.9%
7m2wE01 1.20.120.1900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain 0.74 67.0 4.64e-01 100.0% 48.7%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.74 66.0 4.91e-01 100.0% 82.4%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.74 55.0 5.21e-01 88.4% 66.4%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.74 65.0 6.02e-01 95.8% 77.3%
4alyB00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.74 64.0 5.13e-01 95.8% 61.0%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.73 60.0 6.08e-01 89.5% 88.4%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.73 51.0 4.41e-01 72.6% 94.5%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.73 58.0 5.52e-01 93.7% 71.9%
8etcb01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.73 66.0 5.69e-01 100.0% 78.1%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 51.0 5.59e-01 72.6% 92.0%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 62.0 5.72e-01 93.7% 77.9%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 49.0 5.04e-01 70.5% 73.9%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.72 53.0 5.16e-01 78.9% 98.1%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.71 47.0 5.22e-01 70.5% 90.1%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.70 63.0 5.07e-01 100.0% 94.6%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.70 59.0 5.38e-01 93.7% 71.9%
3pt1A02 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.69 56.0 5.20e-01 87.4% 92.5%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.69 51.0 5.47e-01 84.2% 91.5%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.68 58.0 5.56e-01 95.8% 81.5%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.68 44.0 5.21e-01 74.7% 95.4%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 60.0 4.68e-01 100.0% 78.5%
4pdyA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.68 56.0 4.25e-01 91.6% 70.8%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.66 49.0 4.47e-01 76.8% 99.2%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 46.0 4.26e-01 73.7% 56.7%
2k19A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.66 45.0 4.50e-01 90.5% 68.4%
1v9vA01 1.20.1480.20 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › MAST3 pre-PK domain-like 0.65 50.0 5.00e-01 93.7% 80.0%
2f2gA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.65 56.0 4.29e-01 93.7% 68.8%
4jvsA01 1.20.120.1700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 54.0 4.93e-01 90.5% 96.8%
2x1lA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.64 50.0 4.04e-01 82.1% 68.0%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.63 45.0 4.29e-01 90.5% 62.5%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.63 45.0 3.89e-01 74.7% 57.3%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.63 54.0 4.71e-01 97.9% 80.4%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.63 55.0 5.41e-01 100.0% 97.1%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 53.0 4.92e-01 95.8% 86.0%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 47.0 3.69e-01 85.3% 58.0%
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.59 52.0 4.87e-01 100.0% 89.1%
2oezA02 1.10.3900.10 Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like 0.58 48.0 4.07e-01 90.5% 79.8%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.58 44.0 4.89e-01 95.8% 98.7%
3wurA00 1.20.1420.60 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › 0.56 48.0 4.02e-01 94.7% 56.2%
2w2dD01 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.55 50.0 3.27e-01 100.0% 49.1%
1t33A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 44.0 3.70e-01 89.5% 93.7%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 46.0 4.73e-01 100.0% 98.9%
ECOD (88)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3915047 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.84 61.0 5.86e-01 74.7% 68.6%
3624539 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.83 52.0 5.29e-01 74.7% 64.2%
3600308 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 75.0 5.46e-01 100.0% 38.7%
3587197 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 73.0 6.21e-01 95.8% 67.3%
3573589 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.82 72.0 7.06e-01 93.7% 96.0%
3422266 3562.1.1.0 ↗ alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 0.81 71.0 6.44e-01 94.7% 80.8%
4017411 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.81 73.0 6.21e-01 98.9% 88.7%
3541787 4177.2.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › TBK1_CCD1 0.79 73.0 5.15e-01 100.0% 72.4%
3741398 632.1.1.8 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › SOG2 0.79 71.0 6.31e-01 96.8% 71.5%
5023098 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.79 72.0 6.52e-01 100.0% 87.2%
3250501 611.8.1.1 ↗ alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › Ariadne 0.78 67.0 5.44e-01 91.6% 54.7%
4175767 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.78 70.0 6.82e-01 97.9% 96.2%
4138735 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.78 67.0 6.61e-01 92.6% 96.0%
5018556 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.78 71.0 6.64e-01 100.0% 93.9%
4988447 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.78 71.0 6.65e-01 100.0% 94.8%
4214525 632.22.1.1 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA 0.78 69.0 6.87e-01 97.9% 100.0%
4026675 603.1.1.172 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF1617 0.77 50.0 4.68e-01 70.5% 53.9%
5042057 3871.1.1.0 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST 0.77 65.0 6.59e-01 90.5% 93.5%
5041317 601.30.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.77 67.0 6.14e-01 97.9% 72.0%
3240453 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.77 53.0 5.21e-01 70.5% 67.0%
3453285 3562.1.1.11 ↗ alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG 0.77 68.0 6.00e-01 95.8% 70.4%
3230496 605.4.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.77 62.0 6.53e-01 89.5% 97.6%
4393454 632.15.1.6 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › DUF2678 0.76 63.0 6.26e-01 90.5% 85.0%
3547209 192.15.1.204 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF2678 0.76 63.0 6.21e-01 90.5% 85.0%
5082524 601.30.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.75 68.0 6.13e-01 100.0% 73.1%
4014198 611.9.1.0 ↗ alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.75 66.0 5.88e-01 95.8% 89.6%
5014639 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.75 67.0 6.64e-01 96.8% 95.0%
3924651 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 49.0 4.97e-01 73.7% 66.3%
3987006 5086.1.1.93 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA 0.75 54.0 4.73e-01 74.7% 54.3%
4013887 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.75 66.0 5.82e-01 96.8% 87.1%
3727197 5069.1.1.7 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.75 66.0 5.36e-01 94.7% 59.4%
4025051 601.30.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.75 68.0 5.81e-01 100.0% 82.7%
5076088 5039.1.1.0 ↗ alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like 0.75 68.0 6.03e-01 100.0% 79.3%
4010479 325.1.7.48 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25885 0.75 54.0 4.82e-01 74.7% 58.5%
3285409 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 68.0 5.43e-01 100.0% 88.1%
3724548 611.7.1.10 ↗ alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Helo_like_N 0.74 62.0 5.53e-01 90.5% 86.7%
3797208 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.74 62.0 5.30e-01 97.9% 57.3%
4955309 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.74 57.0 6.17e-01 90.5% 98.8%
3166260 1.1.7.123 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25885 0.74 53.0 4.77e-01 74.7% 57.7%
3967813 5086.1.1.93 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA 0.74 53.0 4.77e-01 74.7% 58.5%
3934927 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 51.0 5.10e-01 72.6% 70.0%
3285558 150.8.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.74 66.0 5.44e-01 98.9% 93.5%
3225163 633.21.1.0 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.73 66.0 5.97e-01 100.0% 74.6%
3728487 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 67.0 5.29e-01 100.0% 52.1%
3971026 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.73 54.0 4.95e-01 77.9% 61.6%
4020994 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.73 62.0 5.43e-01 93.7% 74.5%
3205948 5069.1.1.7 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.73 63.0 5.16e-01 94.7% 58.9%
3186004 604.6.1.1 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.73 51.0 5.08e-01 74.7% 69.0%
4944333 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.73 61.0 5.54e-01 89.5% 68.0%
5055497 601.30.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.72 65.0 5.53e-01 100.0% 69.7%
3386700 304.58.1.0 ↗ a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.72 51.0 3.56e-01 73.7% 41.0%
3265343 5001.1.1.39 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 0.72 65.0 4.60e-01 100.0% 64.8%
5047411 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.72 64.0 5.05e-01 98.9% 74.4%
4371240 632.7.1.55 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF2605 0.72 59.0 5.92e-01 92.6% 88.4%
3717920 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.71 63.0 5.35e-01 97.9% 61.9%
4023374 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.71 63.0 5.59e-01 97.9% 71.1%
3692494 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.71 64.0 5.58e-01 100.0% 71.0%
3647788 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.71 59.0 5.99e-01 92.6% 91.6%
3804981 192.29.1.7 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM192 0.71 65.0 5.47e-01 100.0% 69.0%
2708 101.1.2.49 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.71 49.0 4.05e-01 72.6% 40.2%
3886622 192.29.1.57 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ninjurin 0.71 61.0 5.39e-01 93.7% 97.0%
3466160 611.9.1.4 ↗ alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.71 62.0 5.57e-01 95.8% 80.0%
5009681 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.70 62.0 5.43e-01 96.8% 78.6%
4675311 632.19.1.5 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › TMEM208_SND2 0.70 59.0 5.43e-01 91.6% 72.5%
3975942 601.4.1.6 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.69 62.0 5.62e-01 100.0% 79.2%
5026394 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 61.0 5.77e-01 98.9% 92.2%
4596162 3615.1.1.0 ↗ alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.68 59.0 5.24e-01 96.8% 67.2%
3586473 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.68 61.0 4.31e-01 98.9% 38.3%
2323977 1198.1.1.0 ↗ alpha bundles › BTA121 › BTA121 › BTA121 0.68 55.0 4.96e-01 95.8% 63.2%
3946576 5086.1.1.66 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR 0.68 51.0 4.54e-01 80.0% 64.4%
3964081 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.67 57.0 4.96e-01 94.7% 64.4%
4011280 611.9.1.0 ↗ alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.67 56.0 4.93e-01 92.6% 79.3%
4934608 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 59.0 5.20e-01 98.9% 75.0%
4008609 1203.1.2.7 ↗ alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR 0.66 51.0 4.47e-01 81.1% 62.9%
3488340 601.1.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.66 56.0 5.33e-01 95.8% 91.3%
3274518 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.65 57.0 5.12e-01 98.9% 71.1%
4283760 1203.1.2.7 ↗ alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › GNVR 0.65 51.0 4.46e-01 83.2% 62.9%
3482907 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.65 45.0 4.23e-01 73.7% 59.1%
3332512 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 57.0 4.58e-01 98.9% 73.2%
3681806 5027.1.1.9 ↗ extended segments › Preprotein translocase SecE subunit › Preprotein translocase SecE subunit › Preprotein translocase SecE subunit › DUF641 0.64 57.0 5.34e-01 100.0% 80.0%
3607239 5069.1.1.7 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.64 57.0 4.34e-01 98.9% 48.4%
3227811 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.64 57.0 4.88e-01 100.0% 67.1%
4023478 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.63 52.0 4.24e-01 96.8% 46.3%
4683248 5086.1.1.66 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › GNVR 0.63 49.0 4.32e-01 83.2% 62.9%
3988973 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 57.0 5.30e-01 100.0% 85.0%
3703280 5069.1.1.7 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.63 55.0 4.28e-01 97.9% 54.3%
4880296 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.62 47.0 4.88e-01 80.0% 97.7%
4423640 5059.1.1.5 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.61 47.0 3.19e-01 82.1% 98.9%