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E4_ORFD

Euk-Vir

Skunk_adenovirus_PB1

E4_ORFD__YP_009162609__Skunk_adenovirus_PB1__1641642

Identity

Accession:
YP_009162609 ↗
Protein ID:
E4_ORFD
Kingdom:
euk

Quality

85.8 mean pLDDT

Taxonomy

Bamfordvirae› Preplasmiviricota› Pharingeaviricetes› Rowavirales› Adenoviridae› Mastadenovirus› Skunk_adenovirus_PB1

TaxID: 1641642

Cluster

View cluster (63 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-122
PDB
Domain cluster: rep: E4_ORF_C__YP_009325359__Bat_mastadenovirus_G__2015376__D17-123
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.75 64.0 4.93e-01 100.0% 43.9%
2r7rA04 3.30.70.2480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.75 54.0 4.89e-01 97.5% 56.1%
3hozA02 3.30.1360.140 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.74 46.0 4.91e-01 71.2% 70.9%
5wm1A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.74 54.0 5.60e-01 97.5% 80.7%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.74 48.0 5.66e-01 94.1% 95.1%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.74 68.0 6.82e-01 100.0% 99.2%
3w7bA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.73 52.0 5.90e-01 98.3% 97.7%
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.73 50.0 5.10e-01 100.0% 71.6%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.73 59.0 5.73e-01 100.0% 78.5%
3n0vA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.72 49.0 5.71e-01 98.3% 97.6%
1yz7A02 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.72 52.0 5.83e-01 95.8% 97.8%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.71 47.0 5.45e-01 95.8% 94.1%
3luyA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.71 50.0 5.63e-01 100.0% 95.5%
2raqA01 3.30.70.1340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › MTH889-like domain 0.71 50.0 5.77e-01 100.0% 100.0%
2fyxA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.70 58.0 5.63e-01 97.5% 80.0%
2y8yA01 3.30.70.1200 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 0.70 49.0 5.56e-01 100.0% 97.7%
2dt9A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 46.0 5.48e-01 95.8% 100.0%
3s1tA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 47.0 5.50e-01 95.8% 100.0%
3pjxA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.70 59.0 5.09e-01 99.2% 59.1%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 48.0 5.45e-01 90.7% 96.6%
2khdA00 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 46.0 4.79e-01 82.2% 73.1%
4dmzA02 3.30.70.2880 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 54.0 5.19e-01 99.2% 71.5%
3n79A01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.69 45.0 5.32e-01 100.0% 100.0%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.69 53.0 4.70e-01 100.0% 57.6%
3otdA00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.69 63.0 4.94e-01 100.0% 92.5%
8gf5C01 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 60.0 5.61e-01 95.8% 97.2%
4ushA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 47.0 4.94e-01 99.2% 81.6%
3tqeA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.67 41.0 5.09e-01 98.3% 100.0%
4kgmA00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.67 61.0 4.87e-01 100.0% 90.9%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 46.0 5.28e-01 92.4% 97.6%
2cpxA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.66 44.0 5.17e-01 94.9% 100.0%
7x4lC02 3.90.1150.160 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.66 45.0 4.38e-01 79.7% 63.3%
3hvwA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 55.0 4.97e-01 98.3% 67.3%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.65 45.0 4.04e-01 99.2% 50.3%
1f3vA00 3.30.70.680 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TRADD, N-terminal domain 0.65 59.0 5.36e-01 100.0% 84.2%
1vdhA01 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.65 51.0 5.11e-01 100.0% 81.0%
3wx4A00 3.30.70.2770 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 44.0 4.77e-01 83.9% 84.7%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 50.0 5.37e-01 98.3% 99.0%
1xmbA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 52.0 5.58e-01 99.2% 100.0%
6gmhK00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.64 42.0 4.24e-01 83.9% 67.0%
2a6mA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.64 57.0 5.56e-01 99.2% 88.5%
4u9rA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 43.0 4.92e-01 78.0% 98.8%
4qjvB00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.64 42.0 4.56e-01 83.9% 83.0%
3kg0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 48.0 5.17e-01 98.3% 95.9%
5xogK00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.63 41.0 4.21e-01 83.9% 68.1%
2g47A04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.63 57.0 4.52e-01 100.0% 72.5%
2fgeA03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 56.0 4.48e-01 100.0% 68.6%
3uebF00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.62 49.0 5.27e-01 84.7% 100.0%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.62 48.0 5.00e-01 94.1% 89.8%
3amiA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 55.0 4.67e-01 100.0% 89.4%
1xppD00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.62 39.0 4.16e-01 81.4% 73.3%
1t0tV02 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.61 49.0 5.03e-01 100.0% 91.0%
2oikA00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.61 45.0 4.30e-01 77.1% 77.7%
3fmbA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 48.0 5.09e-01 97.5% 100.0%
3cxjA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.61 46.0 4.35e-01 88.1% 66.0%
3w3sA01 3.30.70.1920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 50.0 4.50e-01 100.0% 63.7%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 45.0 4.89e-01 97.5% 99.0%
2od6C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 49.0 5.12e-01 100.0% 99.1%
3i3wA04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.59 38.0 4.55e-01 83.1% 100.0%
2r4fA03 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.59 52.0 5.22e-01 97.5% 100.0%
1t02A02 3.90.770.10 Alpha Beta › Alpha-Beta Complex › 3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2 › 3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2 0.59 45.0 3.48e-01 80.5% 59.5%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 46.0 4.84e-01 99.2% 98.0%
3p0tA00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.58 43.0 4.09e-01 77.1% 75.0%
2qv6A01 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.58 52.0 5.11e-01 98.3% 100.0%
3i24B00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.57 47.0 4.48e-01 88.1% 80.6%
2uvaG03 3.30.70.3320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 42.0 4.36e-01 94.1% 83.3%
2il5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.56 44.0 3.95e-01 83.1% 96.9%
2g47A03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 48.0 3.96e-01 99.2% 71.8%
1q2lA03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 47.0 3.92e-01 100.0% 74.8%
2mouA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 42.0 3.52e-01 86.4% 76.4%
5vnxA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 39.0 3.75e-01 77.1% 95.6%
2raaA00 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.51 42.0 3.75e-01 90.7% 96.1%
2uvaG12 3.30.70.3330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 45.0 4.45e-01 97.5% 95.3%
4y2fA00 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.51 38.0 3.58e-01 78.0% 83.9%
ECOD (91)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4469636 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.81 56.0 6.47e-01 95.8% 97.6%
4100594 4955.1.1.1 ↗ a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_7 0.81 52.0 5.22e-01 72.9% 64.2%
5019384 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.79 55.0 6.05e-01 90.7% 88.4%
4627501 305.1.1.0 ↗ a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase 0.77 50.0 5.54e-01 83.1% 83.0%
5054097 305.1.1.10 ↗ a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › PF27806 0.77 49.0 5.73e-01 82.2% 90.6%
3599154 4955.1.1.0 ↗ a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.76 51.0 5.00e-01 82.2% 63.1%
4032118 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.76 62.0 5.87e-01 98.3% 73.6%
5035383 305.2.1.3 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › PF27806 0.75 50.0 5.62e-01 82.2% 87.8%
5077552 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.75 53.0 5.88e-01 84.7% 90.5%
1146572 304.152.1.1 ↗ a+b two layers › Alpha-beta plaits › E4-ORF3 › E4-ORF3 › Adeno_E4_ORF3 0.74 67.0 6.82e-01 98.3% 99.1%
5055979 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.74 54.0 5.98e-01 89.0% 93.7%
4540833 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.74 51.0 5.92e-01 96.6% 98.8%
4978126 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.74 48.0 5.76e-01 83.9% 100.0%
3985106 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.74 62.0 6.29e-01 100.0% 91.3%
5010022 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.73 51.0 5.90e-01 82.2% 100.0%
3280378 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 58.0 5.17e-01 100.0% 60.0%
139956 304.8.1.16 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › 117-like_vir 0.73 50.0 5.10e-01 100.0% 71.6%
5116 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.73 59.0 5.73e-01 100.0% 78.5%
3973743 101.1.2.849 ↗ alpha arrays › HTH › HTH › winged helix domain › GDH_ACT2 0.72 48.0 5.30e-01 81.4% 84.2%
4971835 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.72 54.0 5.50e-01 100.0% 80.0%
3186355 304.48.1.21 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1,Thg1C 0.72 66.0 4.96e-01 100.0% 43.2%
3640423 304.48.1.21 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1,Thg1C 0.72 65.0 4.98e-01 100.0% 44.6%
5076402 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.72 50.0 5.71e-01 84.7% 98.8%
3839917 304.28.1.4 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st 0.72 53.0 5.55e-01 95.8% 85.7%
4990360 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.72 47.0 5.52e-01 85.6% 97.5%
4664239 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.72 48.0 5.37e-01 100.0% 90.0%
3973565 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.71 54.0 5.81e-01 95.8% 93.0%
4964850 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.71 53.0 5.26e-01 98.3% 73.6%
402953 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.71 59.0 5.57e-01 100.0% 74.5%
3973601 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.71 53.0 5.72e-01 96.6% 93.0%
5021604 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.71 58.0 5.87e-01 97.5% 89.6%
4994778 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.70 60.0 5.78e-01 99.2% 82.3%
4983053 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.70 49.0 5.60e-01 90.7% 100.0%
4074038 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.70 52.0 5.33e-01 100.0% 80.9%
5002487 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.69 58.0 5.58e-01 100.0% 78.5%
5053097 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.69 51.0 5.57e-01 99.2% 94.7%
3605282 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.69 56.0 4.81e-01 99.2% 56.1%
3838293 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.69 57.0 5.65e-01 97.5% 84.8%
3479414 304.20.1.2 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › Nrap_D3 0.69 59.0 5.30e-01 92.4% 96.2%
3986660 304.55.2.0 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.68 52.0 5.58e-01 99.2% 96.0%
5072410 306.6.1.6 ↗ a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › GH3_C 0.68 48.0 5.32e-01 84.7% 94.4%
3825753 304.20.1.1 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP_RNA-bind 0.68 56.0 5.75e-01 96.6% 91.3%
4993060 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.68 58.0 5.40e-01 100.0% 74.0%
3946660 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.67 56.0 5.58e-01 88.1% 85.8%
5018524 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.67 53.0 5.48e-01 93.2% 90.9%
5065478 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.67 48.0 5.42e-01 95.8% 100.0%
3895696 304.151.1.5 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › JAG1 0.67 55.0 5.71e-01 93.2% 95.5%
5074728 304.162.1.0 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.67 45.0 5.14e-01 94.1% 100.0%
4008380 304.55.2.0 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.67 60.0 6.02e-01 100.0% 100.0%
5017694 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.66 59.0 5.46e-01 100.0% 76.7%
4980122 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.66 48.0 4.87e-01 83.1% 75.0%
3861271 304.47.1.0 ↗ a+b two layers › Alpha-beta plaits › SEA domain › SEA domain 0.66 53.0 5.61e-01 94.1% 96.2%
3398955 2004.1.1.417 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, AAA_21 0.66 47.0 3.35e-01 99.2% 25.6%
3588477 304.31.1.1 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red 0.65 56.0 5.84e-01 100.0% 100.0%
3175838 309.1.1.11 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.65 58.0 4.72e-01 99.2% 79.1%
3281355 304.12.1.12 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › GDH_ACT2 0.65 48.0 5.05e-01 78.0% 86.7%
2756612 304.31.1.1 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red 0.64 58.0 5.77e-01 99.2% 100.0%
None — 0.64 58.0 5.33e-01 100.0% 85.6%
3365716 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 42.0 4.78e-01 83.9% 91.8%
3382026 304.55.1.20 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Helitron_like_N, REP_ORF2-G2P 0.64 58.0 5.39e-01 100.0% 86.6%
3593893 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 53.0 4.47e-01 100.0% 54.4%
5005078 304.48.1.113 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › mCpol 0.63 47.0 4.66e-01 95.8% 73.6%
3164824 309.1.1.4 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.63 55.0 4.80e-01 97.5% 90.3%
4605207 304.57.1.0 ↗ a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.63 52.0 5.30e-01 100.0% 89.6%
5002573 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 54.0 4.86e-01 99.2% 67.3%
3227174 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 46.0 5.11e-01 94.9% 100.0%
3929061 4955.1.1.0 ↗ a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.62 42.0 4.56e-01 83.9% 85.3%
142220 309.1.1.4 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.62 55.0 4.66e-01 100.0% 89.0%
3413369 304.151.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase 0.62 53.0 5.15e-01 93.2% 90.8%
3675857 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.62 47.0 4.02e-01 100.0% 50.8%
3782905 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.62 54.0 4.28e-01 96.6% 50.6%
3515531 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 54.0 3.49e-01 98.3% 23.5%
146692 304.4.1.9 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Chlor_dismutase 0.61 49.0 4.98e-01 100.0% 88.6%
3934872 3122.1.1.2 ↗ a+b complex topology › MESD › MESD › MESD › SCVP 0.61 47.0 4.99e-01 98.3% 91.4%
4182456 331.2.1.1 ↗ a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.61 42.0 4.81e-01 90.7% 98.8%
5041991 3501.1.1.0 ↗ a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 0.61 42.0 4.74e-01 82.2% 93.3%
3485848 304.47.1.0 ↗ a+b two layers › Alpha-beta plaits › SEA domain › SEA domain 0.60 43.0 4.80e-01 74.6% 100.0%
4070229 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.60 52.0 5.39e-01 99.2% 100.0%
4978118 241.1.1.5 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF2299 0.60 44.0 4.10e-01 86.4% 59.4%
3646496 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.60 49.0 5.19e-01 96.6% 100.0%
3968643 241.1.1.8 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF2170 0.60 41.0 3.95e-01 85.6% 61.5%
5057997 312.1.1.2 ↗ a+b three layers › HIT-like › HIT-related › HIT-related › HIT 0.59 43.0 4.24e-01 74.6% 76.8%
3421609 304.7.1.0 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.59 49.0 5.11e-01 96.6% 100.0%
3489670 309.1.1.0 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.58 51.0 4.19e-01 100.0% 69.6%
4515869 331.2.1.1 ↗ a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.57 38.0 4.26e-01 82.2% 91.0%
3526003 304.9.1.87 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF30891 0.57 49.0 4.98e-01 95.8% 98.3%
4047925 304.4.1.4 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.56 48.0 4.93e-01 100.0% 96.5%
5011307 304.116.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor 0.55 43.0 4.58e-01 100.0% 98.0%
3973859 312.1.1.2 ↗ a+b three layers › HIT-like › HIT-related › HIT-related › HIT 0.54 42.0 4.00e-01 84.7% 75.2%
142183 848.1.1.0 ↗ a+b complex topology › Hsp33 domain › Hsp33 domain › Hsp33 domain 0.52 44.0 3.59e-01 94.9% 55.8%
5006044 206.1.1.268 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF6206 0.51 44.0 3.35e-01 94.9% 85.8%