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E6

Euk-Vir

Macaca_fascicularis_papillomavirus_1

E6__ABM67065__Macaca_fascicularis_papillomavirus_1__2847841

Identity

Accession:
ABM67065 ↗
Protein ID:
E6
Kingdom:
euk

Quality

96.5 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Betapapillomavirus› Macaca_fascicularis_papillomavirus_1

TaxID: 2847841

Cluster

View cluster (138 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-64
PDB
Domain cluster: rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 32.7 1.20e-07 68.4% 34.5%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ljxA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.85 77.0 6.76e-01 100.0% 69.5%
2m3lA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.82 72.0 6.61e-01 100.0% 77.6%
2gviA03 3.30.60.20 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.71 41.0 4.96e-01 78.9% 97.1%
4n4fA02 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.64 40.0 4.50e-01 77.2% 90.0%
3vd6C01 3.30.50.10 Alpha Beta › 2-Layer Sandwich › Erythroid Transcription Factor GATA-1; Chain A › Erythroid Transcription Factor GATA-1, subunit A 0.63 34.0 3.94e-01 73.7% 73.2%
4bbqA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.61 46.0 4.35e-01 91.2% 68.6%
3vhtB02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.58 31.0 3.74e-01 93.0% 85.3%
2epcA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.57 29.0 3.41e-01 75.4% 72.7%
2lo3A01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.57 28.0 3.54e-01 73.7% 89.7%
3vk6A01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.55 35.0 3.54e-01 78.9% 62.7%
3e59B02 3.30.60.140 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.55 35.0 3.94e-01 71.9% 100.0%
1c0wA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 41.0 3.85e-01 82.5% 64.4%
1yc5A02 3.30.1600.10 Alpha Beta › 2-Layer Sandwich › SIR2/SIRT2 'Small Domain' › SIR2/SIRT2 'Small Domain' 0.54 43.0 3.88e-01 100.0% 61.9%
5i41B00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.53 37.0 3.54e-01 73.7% 70.1%
2l02A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.51e-01 80.7% 58.5%
5dahA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.53 42.0 3.20e-01 93.0% 51.3%
2luyA01 3.30.60.210 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Stc1 domain 0.52 43.0 4.39e-01 98.2% 96.5%
4fbdA01 3.30.2310.50 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › Protein of unknown function (DUF3228), domain 1 0.52 44.0 3.60e-01 100.0% 96.5%
3hcsA02 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.52 33.0 3.41e-01 87.7% 69.2%
5y2vC01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 38.0 3.43e-01 82.5% 63.5%
5hkxA04 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.51 32.0 3.42e-01 78.9% 79.5%
5tdrA00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.51 31.0 3.00e-01 94.7% 47.1%
3goxA03 3.40.1800.10 Alpha Beta › 3-Layer(aba) Sandwich › His-Me finger endonuclease fold › His-Me finger endonucleases 0.50 39.0 3.56e-01 100.0% 61.7%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4802726 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.98 94.0 9.01e-01 100.0% 89.1%
185477 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.91 68.0 6.42e-01 100.0% 67.2%
3036062 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.88 79.0 7.16e-01 100.0% 75.0%
185478 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.87 79.0 7.54e-01 100.0% 89.2%
1734555 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.86 78.0 6.89e-01 100.0% 70.4%
4802727 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.83 73.0 6.77e-01 96.5% 78.6%
3164830 377.1.1.7 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › zf-dskA_traR 0.71 46.0 5.26e-01 100.0% 95.0%
2755068 376.1.1.12 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING-like 0.69 37.0 3.90e-01 71.9% 58.0%
3796016 376.1.3.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.67 39.0 4.03e-01 75.4% 60.0%
3486059 386.1.1.20 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-met 0.63 40.0 4.34e-01 98.2% 90.0%
3394822 375.1.1.179 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.61 39.0 2.71e-01 82.5% 19.0%
3485267 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.60 37.0 3.27e-01 78.9% 41.2%
5052386 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.60 37.0 4.15e-01 93.0% 90.0%
3550392 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.60 38.0 2.70e-01 82.5% 20.0%
3910824 213.1.1.44 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › ATE_C 0.59 44.0 3.12e-01 100.0% 23.3%
3937568 376.1.1.37 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › SLX1_C 0.59 37.0 3.24e-01 71.9% 42.4%
3938245 375.1.1.179 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.58 37.0 2.56e-01 82.5% 17.3%
3616970 386.1.1.68 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › NOA36 0.58 34.0 3.96e-01 71.9% 82.5%
4055899 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.58 32.0 3.93e-01 91.2% 100.0%
4011434 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.58 36.0 3.11e-01 91.2% 37.9%
3223233 375.1.1.179 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.58 37.0 2.50e-01 82.5% 16.1%
864518 386.1.1.39 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-WRNIP1_ubi 0.58 31.0 3.74e-01 93.0% 85.3%
3882708 386.1.1.48 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf_C2HC_14 0.57 33.0 3.88e-01 82.5% 91.4%
3539459 386.1.1.3 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-TRAF 0.57 34.0 3.56e-01 87.7% 66.0%
3642366 376.1.3.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD 0.56 41.0 4.10e-01 78.9% 75.0%
3237398 376.1.1.20 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX 0.56 39.0 3.22e-01 87.7% 42.0%
3275237 376.1.3.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.55 41.0 4.06e-01 84.2% 83.3%
3396475 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.55 37.0 3.36e-01 71.9% 73.8%
2163511 375.1.1.18 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.54 34.0 3.74e-01 93.0% 85.7%
4021522 376.1.1.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.54 34.0 3.54e-01 78.9% 70.0%
4920017 375.1.1.18 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.54 36.0 4.01e-01 71.9% 95.5%
3250670 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.54 31.0 3.68e-01 89.5% 100.0%
4890082 375.1.1.18 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.54 35.0 3.90e-01 71.9% 92.9%
3947868 2484.1.1.87 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MreB-like_C 0.53 37.0 2.66e-01 82.5% 24.2%
3260450 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.53 34.0 3.32e-01 93.0% 56.9%
4048121 386.1.1.12 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › Sgf11 0.53 33.0 2.91e-01 89.5% 41.2%
1548205 375.1.1.18 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.52 33.0 3.48e-01 82.5% 73.9%
4644171 7571.1.1.1 ↗ a/b three-layered sandwiches › Formyltransferase › Formyltransferase › Formyltransferase › Formyl_trans_N 0.52 35.0 2.47e-01 71.9% 86.0%
4256744 69.1.2.1 ↗ beta complex topology › Hedgehog/intein › Hedgehog/intein › AXH › AXH 0.52 38.0 3.08e-01 86.0% 61.5%
3805701 376.1.1.8 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › U-box 0.52 32.0 2.90e-01 78.9% 40.0%
4650888 2003.1.4.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 0.51 42.0 2.86e-01 98.2% 37.6%
3607216 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.51 36.0 3.90e-01 98.2% 95.6%
3748739 376.1.1.29 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4_4 0.51 32.0 3.16e-01 78.9% 55.4%
1247294 375.1.1.18 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.51 32.0 3.41e-01 94.7% 77.1%
4028586 376.1.1.23 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4_2 0.50 33.0 2.95e-01 78.9% 42.4%
3178296 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.50 30.0 2.89e-01 78.9% 45.7%
D2 high residues 74-137
PDB
Domain cluster: rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 58.6 1.10e-15 96.9% 54.5%