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E6
Euk-VirHuman_papillomavirus_127
E6__YP_003858573__Human_papillomavirus_127__746832
Identity
- Accession:
- YP_003858573 ↗
- Protein ID:
- E6
- Kingdom:
- euk
Quality
95.5
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Gammapapillomavirus›
Human_papillomavirus_127
TaxID: 746832
Cluster
View cluster (138 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 9-66
Domain cluster:
rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 34.9 | 2.60e-08 | 69.0% | 35.4% |
D2
high
residues 69-131
Domain cluster:
rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 51.7 | 1.50e-13 | 100.0% | 56.4% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.88 | 74.0 | 6.91e-01 | 90.5% | 75.0% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.79 | 64.0 | 5.84e-01 | 87.3% | 67.1% |
| 1y8fA00 | 3.30.60.20 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.53 | 34.0 | 3.59e-01 | 88.9% | 78.4% |
| 3en8A01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 39.0 | 3.40e-01 | 85.7% | 87.5% |
| 4ht4A00 | 3.30.930.30 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › | 0.51 | 40.0 | 2.97e-01 | 92.1% | 68.0% |
| 3f14A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 38.0 | 3.29e-01 | 85.7% | 88.4% |
| 3ke7B00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 38.0 | 3.11e-01 | 84.1% | 78.2% |
| 3dmcA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.50 | 38.0 | 3.11e-01 | 87.3% | 82.8% |
| 3f8xB00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.50 | 38.0 | 3.12e-01 | 87.3% | 76.5% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.97 | 93.0 | 8.92e-01 | 100.0% | 90.0% |
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.97 | 93.0 | 8.36e-01 | 100.0% | 77.8% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.85 | 70.0 | 6.95e-01 | 88.9% | 87.7% |
| 4802726 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.81 | 64.0 | 6.41e-01 | 85.7% | 84.4% |
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.74 | 63.0 | 5.92e-01 | 93.7% | 77.6% |
| 3219090 | 243.1.1.47 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF5390 | 0.56 | 40.0 | 3.29e-01 | 77.8% | 89.4% |
| 3290683 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.53 | 39.0 | 3.26e-01 | 85.7% | 81.2% |
| 3960172 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.52 | 39.0 | 3.32e-01 | 85.7% | 89.8% |
| 3185449 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.51 | 37.0 | 2.98e-01 | 79.4% | 79.0% |
| 2605238 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.51 | 41.0 | 3.57e-01 | 93.7% | 97.2% |
| 5015075 | 221.12.1.0 ↗ | a+b two layers › beta-Grasp | 0.51 | 38.0 | 3.86e-01 | 87.3% | 100.0% |
| 4021528 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.50 | 36.0 | 2.87e-01 | 77.8% | 83.3% |