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E6

Euk-Vir

Camelus_dromedarius_papillomavirus_1

E6__YP_004306465__Camelus_dromedarius_papillomavirus_1__996650

Identity

Accession:
YP_004306465 ↗
Protein ID:
E6
Kingdom:
euk

Quality

87.6 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Deltapapillomavirus› Camelus_dromedarius_papillomavirus_1

TaxID: 996650

Cluster

View cluster (138 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-57
PDB
Domain cluster: rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 32.4 1.60e-07 84.6% 38.2%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2m3lA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.78 65.0 5.73e-01 92.3% 78.9%
2ljxA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.75 63.0 5.48e-01 96.2% 70.7%
4nwbA02 3.90.105.20 Alpha Beta › Alpha-Beta Complex › Molybdopterin biosynthesis moea protein, domain 2 › Ribosomal protein L10, N-terminal fragment, domain II 0.63 46.0 3.84e-01 76.9% 100.0%
1mukA02 3.90.1850.10 Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 0.57 38.0 2.22e-01 71.2% 42.9%
2f1rA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 41.0 3.12e-01 84.6% 100.0%
3d8kD00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.56 40.0 2.49e-01 78.8% 51.4%
5ttjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 40.0 2.68e-01 76.9% 24.9%
4uyiA00 3.30.710.10 Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A 0.56 43.0 3.36e-01 90.4% 41.7%
2fclA00 3.30.460.40 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.55 44.0 3.29e-01 98.1% 82.7%
1i27A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 40.0 3.63e-01 78.8% 68.5%
2l02A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 40.0 3.55e-01 84.6% 65.9%
2cklB01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.54 35.0 3.21e-01 88.5% 47.9%
3cuoD00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 39.0 3.38e-01 84.6% 62.8%
1ac5A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 38.0 2.30e-01 82.7% 22.4%
6j0eB01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.07e-01 80.8% 47.9%
2rdpA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 40.0 3.03e-01 84.6% 40.7%
1ybtB00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.53 38.0 2.83e-01 84.6% 89.0%
2qh5B00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.52 39.0 2.59e-01 84.6% 85.5%
4rs8A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 38.0 3.39e-01 82.7% 69.0%
4hw0C00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 36.0 3.12e-01 76.9% 57.0%
1earA02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.52 36.0 3.35e-01 75.0% 62.3%
5zyrA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 39.0 2.87e-01 84.6% 37.7%
2yvwA02 3.65.10.10 Alpha Beta › Alpha-beta prism › UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain › Enolpyruvate transferase domain 0.52 40.0 2.76e-01 90.4% 61.2%
2xfvA00 3.10.260.30 Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › 0.51 38.0 3.12e-01 84.6% 63.0%
5dahA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.51 36.0 2.71e-01 78.8% 57.8%
1tbxB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 37.0 3.25e-01 82.7% 68.9%
1k3xA02 1.10.8.50 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 41.0 3.16e-01 92.3% 45.7%
3cuqB03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 34.0 3.22e-01 73.1% 71.0%
1sd4A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 36.0 3.45e-01 80.8% 84.4%
4gyiA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 36.0 3.15e-01 82.7% 68.8%
ECOD (43)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
185477 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.97 88.0 7.92e-01 96.2% 74.6%
4802726 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.90 78.0 7.23e-01 92.3% 90.6%
1734555 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.84 72.0 6.13e-01 94.2% 72.8%
3036062 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.83 75.0 6.56e-01 100.0% 81.6%
4977157 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.65 47.0 4.95e-01 92.3% 88.9%
5055105 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.57 43.0 4.01e-01 86.5% 64.3%
5061454 316.1.1.0 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.57 44.0 3.29e-01 92.3% 90.9%
3921910 376.1.3.11 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf-HC5HC2H_2 0.56 43.0 3.27e-01 88.5% 75.0%
5081465 101.1.2.14 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.56 43.0 3.48e-01 82.7% 53.0%
3244217 101.1.2.506 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_NWD1 0.56 42.0 3.27e-01 84.6% 65.6%
5083603 101.1.2.78 ↗ alpha arrays › HTH › HTH › winged helix domain › AlkZ-like 0.55 38.0 2.83e-01 73.1% 35.7%
5064906 101.1.9.17 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › MerR_1 0.55 39.0 3.85e-01 76.9% 85.5%
3279133 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.55 41.0 3.45e-01 84.6% 70.5%
5067549 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.55 41.0 3.88e-01 84.6% 86.2%
3533128 101.1.2.506 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_NWD1 0.54 41.0 3.31e-01 84.6% 72.7%
None — 0.54 40.0 3.53e-01 84.6% 74.1%
5049209 101.1.2.46 ↗ alpha arrays › HTH › HTH › winged helix domain › HrcA_DNA-bdg 0.54 40.0 3.49e-01 82.7% 65.9%
3922802 101.1.2.506 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_NWD1 0.54 40.0 3.20e-01 84.6% 70.0%
4980135 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 39.0 3.23e-01 82.7% 61.1%
4968035 101.1.2.141 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_24 0.54 40.0 3.36e-01 84.6% 79.6%
3520018 376.1.3.11 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf-HC5HC2H_2 0.54 41.0 3.42e-01 94.2% 75.7%
4946048 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.54 39.0 3.48e-01 80.8% 81.2%
4977549 101.1.2.78 ↗ alpha arrays › HTH › HTH › winged helix domain › AlkZ-like 0.53 39.0 3.56e-01 78.8% 65.7%
4946906 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 39.0 3.29e-01 84.6% 64.0%
3958566 101.1.2.136 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.53 36.0 3.16e-01 75.0% 62.2%
None — 0.53 39.0 3.51e-01 84.6% 80.0%
3642367 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.53 41.0 4.42e-01 88.5% 100.0%
5053841 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.52 37.0 3.43e-01 80.8% 70.7%
5061883 101.1.2.141 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_24 0.52 37.0 3.38e-01 82.7% 66.3%
4968841 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 43.0 2.68e-01 94.2% 24.0%
3281207 101.1.2.136 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_20 0.52 38.0 3.26e-01 82.7% 65.6%
139679 101.1.9.21 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › Swi6_N 0.51 38.0 3.12e-01 84.6% 63.0%
2066836 101.1.2.78 ↗ alpha arrays › HTH › HTH › winged helix domain › AlkZ-like 0.51 37.0 3.30e-01 78.8% 62.8%
4973555 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.51 37.0 2.72e-01 82.7% 37.1%
4929094 101.1.2.150 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_45 0.51 37.0 3.23e-01 82.7% 66.7%
4174817 327.16.1.17 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system › PF27474 0.51 37.0 3.78e-01 78.8% 81.6%
4961224 101.1.2.78 ↗ alpha arrays › HTH › HTH › winged helix domain › AlkZ-like 0.51 36.0 3.37e-01 78.8% 75.7%
4995459 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.51 37.0 2.97e-01 82.7% 55.0%
4983405 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.51 37.0 2.73e-01 82.7% 39.9%
3738415 304.7.1.0 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.51 37.0 3.17e-01 78.8% 55.3%
3909408 101.1.2.68 ↗ alpha arrays › HTH › HTH › winged helix domain › RNA_pol_Rpc34 0.51 37.0 3.35e-01 80.8% 64.0%
3554511 101.1.2.206 ↗ alpha arrays › HTH › HTH › winged helix domain › SAMD1_WH 0.51 36.0 3.26e-01 80.8% 77.5%
5035255 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.50 36.0 3.12e-01 82.7% 58.9%
D2 high residues 61-119
PDB
Domain cluster: rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 41.0 3.20e-10 89.8% 42.7%