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E6
Euk-VirCanis_familiaris_papillomavirus_8
E6__YP_004857842__Canis_familiaris_papillomavirus_8__1081055
Identity
- Accession:
- YP_004857842 ↗
- Protein ID:
- E6
- Kingdom:
- euk
Quality
91.8
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Chipapillomavirus›
Canis_familiaris_papillomavirus_8
TaxID: 1081055
Cluster
View cluster (138 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 9-66
Domain cluster:
rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 31.0 | 4.20e-07 | 58.6% | 30.9% |
D2
high
residues 72-136
Domain cluster:
rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 38.3 | 2.20e-09 | 100.0% | 57.3% |
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.78 | 62.0 | 5.91e-01 | 86.2% | 75.0% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.70 | 54.0 | 5.01e-01 | 83.1% | 67.1% |
| 1kgqA02 | 2.160.10.10 | Mainly Beta › 3 Solenoid › UDP N-Acetylglucosamine Acyltransferase; domain 1 › Hexapeptide repeat proteins | 0.60 | 43.0 | 3.20e-01 | 76.9% | 41.8% |
| 3ke7B00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.57 | 42.0 | 3.48e-01 | 83.1% | 78.9% |
| 3mg1B02 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.56 | 41.0 | 3.45e-01 | 83.1% | 84.8% |
| 2napA03 | 3.40.228.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2 | 0.55 | 43.0 | 3.04e-01 | 89.2% | 98.7% |
| 3en8A01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 41.0 | 3.54e-01 | 83.1% | 87.5% |
| 3fkaB00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 40.0 | 3.40e-01 | 81.5% | 85.8% |
| 4orlA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 39.0 | 3.41e-01 | 83.1% | 91.8% |
| 3f40A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 39.0 | 3.39e-01 | 83.1% | 85.6% |
| 5tgnA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.53 | 39.0 | 3.39e-01 | 83.1% | 89.0% |
| 4h3uA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 38.0 | 3.19e-01 | 83.1% | 81.5% |
| 4i4kA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 37.0 | 3.08e-01 | 81.5% | 81.9% |
| 1r89A01 | 1.10.1410.30 | Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › CCA tRNA nucleotidyltransferase, domain 2 | 0.51 | 38.0 | 3.11e-01 | 81.5% | 55.7% |
| 3a76A01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 37.0 | 3.02e-01 | 81.5% | 82.7% |
| 2f86B00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.50 | 36.0 | 3.03e-01 | 80.0% | 86.8% |
| 3nybA01 | 1.10.1410.10 | Mainly Alpha › Orthogonal Bundle › Poly(a)-polymerase, middle domain › | 0.50 | 37.0 | 2.69e-01 | 81.5% | 84.5% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.91 | 84.0 | 8.16e-01 | 98.5% | 92.9% |
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.86 | 77.0 | 7.12e-01 | 98.5% | 79.0% |
| 4802726 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.75 | 58.0 | 5.85e-01 | 81.5% | 85.9% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.75 | 60.0 | 6.07e-01 | 89.2% | 87.7% |
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.66 | 54.0 | 5.14e-01 | 89.2% | 77.6% |
| 4238159 | 208.1.1.4 ↗ | beta duplicates or obligate multimers › Single-stranded left-handed beta-helix › Trimeric LpxA-like enzymes › Trimeric LpxA-like enzymes › Hexapep,Hexapep_2 | 0.62 | 44.0 | 3.17e-01 | 76.9% | 39.0% |
| 3219337 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.59 | 46.0 | 4.04e-01 | 86.2% | 79.0% |
| 4050622 | 208.1.1.6 ↗ | beta duplicates or obligate multimers › Single-stranded left-handed beta-helix › Trimeric LpxA-like enzymes › Trimeric LpxA-like enzymes › Hexapep_2 | 0.59 | 42.0 | 3.06e-01 | 75.4% | 36.8% |
| 2886759 | 243.1.1.2 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 | 0.59 | 44.0 | 3.53e-01 | 83.1% | 76.3% |
| 3960172 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.59 | 42.0 | 3.55e-01 | 78.5% | 89.8% |
| 3679413 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.58 | 43.0 | 3.23e-01 | 83.1% | 61.7% |
| 3213524 | 243.1.1.82 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF26529 | 0.58 | 42.0 | 3.33e-01 | 81.5% | 77.4% |
| 3957839 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.56 | 41.0 | 3.44e-01 | 83.1% | 80.8% |
| 6395 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.55 | 41.0 | 3.42e-01 | 83.1% | 77.2% |
| 5072383 | 243.1.1.26 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_4 | 0.55 | 41.0 | 3.26e-01 | 83.1% | 78.6% |
| 1146735 | 243.1.1.29 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF4783 | 0.53 | 39.0 | 3.41e-01 | 83.1% | 91.8% |
| 3536326 | 1073.1.1.0 ↗ | alpha arrays › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) | 0.53 | 38.0 | 3.53e-01 | 78.5% | 94.4% |
| 3970325 | 243.1.1.10 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL | 0.53 | 39.0 | 3.17e-01 | 83.1% | 81.4% |
| 2605238 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.51 | 37.0 | 3.33e-01 | 83.1% | 95.3% |
| 3234788 | 243.9.1.2 ↗ | a+b two layers › Cystatin-like › Nuclease A inhibitor (NuiA)-related › Nuclease A inhibitor (NuiA)-related › Maf1 | 0.51 | 44.0 | 3.28e-01 | 100.0% | 67.8% |
| 3721221 | 211.1.1.1 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase | 0.51 | 43.0 | 3.94e-01 | 96.9% | 73.3% |
| 3320752 | 243.1.1.49 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF2358 | 0.51 | 37.0 | 2.99e-01 | 81.5% | 74.5% |
| 5432 | 304.111.1.1 ↗ | a+b two layers › Alpha-beta plaits › PurM C-terminal domain-like › PurM C-terminal domain-like › AIRS_C | 0.51 | 41.0 | 3.19e-01 | 95.4% | 61.3% |