←Back to structures
E6
Euk-VirTrichechus_manatus_latirostris_papillomavirus_4
E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317
Identity
- Accession:
- YP_009177725 ↗
- Protein ID:
- E6
- Kingdom:
- euk
Quality
82.8
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Rhopapillomavirus›
Trichechus_manatus_latirostris_papillomavirus_4
TaxID: 2848317
Cluster
View cluster (138 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 98-164
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 38.9 | 1.50e-09 | 100.0% | 60.9% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.88 | 70.0 | 6.74e-01 | 85.1% | 75.0% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.82 | 63.0 | 5.91e-01 | 82.1% | 67.1% |
| 3majA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.59 | 38.0 | 4.02e-01 | 74.6% | 73.3% |
| 1ub9A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 42.0 | 3.69e-01 | 77.6% | 60.0% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 40.0 | 2.93e-01 | 82.1% | 78.3% |
| 4xrfA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 40.0 | 3.12e-01 | 77.6% | 44.4% |
| 3r0aA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 39.0 | 3.20e-01 | 77.6% | 48.3% |
| 1p4xA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 38.0 | 3.11e-01 | 77.6% | 49.6% |
| 2juoA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.51 | 39.0 | 3.61e-01 | 86.6% | 86.5% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.96 | 89.0 | 8.80e-01 | 97.0% | 92.9% |
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.96 | 87.0 | 8.07e-01 | 95.5% | 79.0% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.84 | 66.0 | 6.70e-01 | 83.6% | 87.7% |
| 4802726 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.79 | 60.0 | 6.14e-01 | 80.6% | 84.4% |
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.77 | 63.0 | 6.07e-01 | 88.1% | 77.6% |
| 4935554 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 40.0 | 4.16e-01 | 82.1% | 75.0% |
| 4978401 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.54 | 39.0 | 3.52e-01 | 77.6% | 54.7% |
| 3787187 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.50 | 34.0 | 2.77e-01 | 70.1% | 82.1% |
| 5015075 | 221.12.1.0 ↗ | a+b two layers › beta-Grasp | 0.50 | 36.0 | 3.77e-01 | 82.1% | 100.0% |
| 3213524 | 243.1.1.82 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF26529 | 0.50 | 36.0 | 2.95e-01 | 82.1% | 80.0% |
D2
medium
residues 1-93
Domain cluster:
rep: E6_protein__YP_008519308__Mustela_putorius_papillomavirus_1__2259540__D8-90
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.82 | 56.0 | 5.97e-01 | 79.6% | 79.3% |
| 4a6dA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.57 | 42.0 | 4.26e-01 | 77.4% | 86.2% |
| 1lvaA04 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 35.0 | 4.21e-01 | 71.0% | 100.0% |
| 1y8fA00 | 3.30.60.20 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.53 | 25.0 | 3.23e-01 | 98.9% | 78.4% |
| 2r3sB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 39.0 | 4.18e-01 | 78.5% | 92.6% |
| 2fbhA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 38.0 | 3.33e-01 | 74.2% | 54.0% |
| 1zarA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 39.0 | 4.05e-01 | 79.6% | 89.9% |
| 4hwiB01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.52 | 36.0 | 4.02e-01 | 96.8% | 95.8% |
| 4etsA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 36.0 | 3.76e-01 | 74.2% | 86.2% |
| 3mq0A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 33.0 | 3.63e-01 | 71.0% | 80.5% |
| 2dloA00 | 2.10.110.10 | Mainly Beta › Ribbon › Cysteine Rich Protein › Cysteine Rich Protein | 0.51 | 29.0 | 3.06e-01 | 75.3% | 60.5% |
| 2j3lA03 | 3.90.960.10 | Alpha Beta › Alpha-Beta Complex › YbaK protein › YbaK/aminoacyl-tRNA synthetase-associated domain | 0.51 | 37.0 | 3.23e-01 | 76.3% | 93.2% |
| 3pfiA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 35.0 | 3.85e-01 | 74.2% | 91.8% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.88 | 55.0 | 6.09e-01 | 95.7% | 77.6% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.83 | 52.0 | 6.18e-01 | 95.7% | 90.8% |
| 185477 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.78 | 42.0 | 5.01e-01 | 96.8% | 76.1% |
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.77 | 53.0 | 5.63e-01 | 92.5% | 80.2% |
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.73 | 49.0 | 5.62e-01 | 92.5% | 92.9% |
| 4017767 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 40.0 | 3.92e-01 | 79.6% | 84.0% |
| 3922396 | 386.1.1.3 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-TRAF | 0.53 | 21.0 | 2.88e-01 | 71.0% | 68.9% |
| 4659973 | 101.1.2.162 ↗ | alpha arrays › HTH › HTH › winged helix domain › DprA_WH | 0.53 | 34.0 | 3.65e-01 | 73.1% | 76.2% |
| 3943470 | 101.1.2.110 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_IclR | 0.52 | 35.0 | 3.71e-01 | 71.0% | 75.3% |
| 4929470 | 101.1.2.15 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR | 0.52 | 40.0 | 3.87e-01 | 81.7% | 72.4% |
| 4352411 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.51 | 22.0 | 2.81e-01 | 72.0% | 68.0% |
| 5019931 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 37.0 | 3.25e-01 | 78.5% | 63.3% |