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E6
Euk-VirCervus_papillomavirus_2
E6__YP_009252391__Cervus_papillomavirus_2__1434070
Identity
- Accession:
- YP_009252391 ↗
- Protein ID:
- E6
- Kingdom:
- euk
Quality
84.7
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Epsilonpapillomavirus›
Cervus_papillomavirus_2
TaxID: 1434070
Cluster
View cluster (138 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 18-56
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 27.0 | 7.10e-06 | 94.9% | 33.6% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.88 | 77.0 | 6.19e-01 | 100.0% | 52.6% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.87 | 76.0 | 5.92e-01 | 100.0% | 47.6% |
| 3mwmA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.60 | 38.0 | 3.46e-01 | 76.9% | 48.1% |
| 5i41B00 | 1.10.1660.10 | Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › | 0.59 | 44.0 | 3.92e-01 | 89.7% | 71.6% |
| 4fbdA01 | 3.30.2310.50 | Alpha Beta › 2-Layer Sandwich › YaeB-like fold › Protein of unknown function (DUF3228), domain 1 | 0.57 | 45.0 | 3.41e-01 | 100.0% | 53.5% |
| 3cr8C02 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.57 | 46.0 | 2.99e-01 | 94.9% | 58.1% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.56 | 37.0 | 2.41e-01 | 74.4% | 13.1% |
| 3e59B02 | 3.30.60.140 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.56 | 45.0 | 4.55e-01 | 89.7% | 92.1% |
| 3l86A00 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.56 | 44.0 | 2.83e-01 | 94.9% | 94.7% |
| 5c68A00 | 3.10.180.10 | Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 | 0.55 | 40.0 | 2.97e-01 | 79.5% | 95.4% |
| 6wqbA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.50 | 39.0 | 2.73e-01 | 89.7% | 58.8% |
| 2xfvA00 | 3.10.260.30 | Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › | 0.50 | 38.0 | 2.90e-01 | 82.1% | 47.2% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185477 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 1.00 | 94.0 | 7.59e-01 | 100.0% | 58.2% |
| 4802726 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.96 | 87.0 | 7.26e-01 | 100.0% | 60.9% |
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.93 | 83.0 | 6.44e-01 | 100.0% | 48.1% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.91 | 80.0 | 6.77e-01 | 100.0% | 61.5% |
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.91 | 80.0 | 6.39e-01 | 100.0% | 51.3% |
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.89 | 78.0 | 6.42e-01 | 100.0% | 55.7% |
| 3233807 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.69 | 49.0 | 4.07e-01 | 100.0% | 42.9% |
| 4450939 | 7531.1.1.1 ↗ | a/b three-layered sandwiches › Carbamate kinase-like › Carbamate kinase-like › Carbamate kinase-like › AA_kinase | 0.57 | 43.0 | 2.78e-01 | 94.9% | 90.0% |
| 3164257 | 2002.1.1.111 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HpcH_HpaI | 0.56 | 39.0 | 2.37e-01 | 71.8% | 42.1% |
| 3462716 | 387.1.5.0 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like | 0.55 | 38.0 | 4.20e-01 | 74.4% | 90.0% |
| 4001675 | 376.1.1.20 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX | 0.54 | 41.0 | 3.63e-01 | 97.4% | 55.0% |
| 3396475 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.54 | 45.0 | 3.66e-01 | 100.0% | 71.2% |
| 4092544 | 102.2.1.4 ↗ | alpha arrays › HhH/H2TH › H2TH › H2TH › H2TH | 0.53 | 35.0 | 2.75e-01 | 71.8% | 44.0% |
| 5001086 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.53 | 38.0 | 2.47e-01 | 79.5% | 31.3% |
| 4623982 | 7531.1.1.1 ↗ | a/b three-layered sandwiches › Carbamate kinase-like › Carbamate kinase-like › Carbamate kinase-like › AA_kinase | 0.52 | 40.0 | 2.53e-01 | 92.3% | 91.9% |
| 3947868 | 2484.1.1.87 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MreB-like_C | 0.52 | 40.0 | 2.66e-01 | 87.2% | 20.0% |
| 4509560 | 2002.1.1.111 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HpcH_HpaI | 0.51 | 36.0 | 2.26e-01 | 79.5% | 64.3% |
| 4825021 | 4.1.1.294 ↗ | beta barrels › SH3 › SH3 › SH3 › Myosin_head | 0.51 | 38.0 | 3.72e-01 | 79.5% | 80.0% |
| 4050184 | 7531.1.1.1 ↗ | a/b three-layered sandwiches › Carbamate kinase-like › Carbamate kinase-like › Carbamate kinase-like › AA_kinase | 0.51 | 39.0 | 2.48e-01 | 92.3% | 88.3% |
| 3731014 | 2002.1.1.111 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HpcH_HpaI | 0.51 | 39.0 | 2.32e-01 | 82.1% | 23.9% |
D2
high
residues 62-132
Domain cluster:
rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 55.7 | 8.60e-15 | 95.8% | 60.9% |