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E6

Euk-Vir

Erethizon_dorsatum_papillomavirus_1

E6__YP_224221__Erethizon_dorsatum_papillomavirus_1__291590

Identity

Accession:
YP_224221 ↗
Protein ID:
E6
Kingdom:
euk

Quality

88.6 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Sigmapapillomavirus› Erethizon_dorsatum_papillomavirus_1

TaxID: 291590

Cluster

View cluster (138 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 28-82
PDB
Domain cluster: rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 33.0 9.80e-08 67.3% 33.6%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ljxA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.88 79.0 6.88e-01 100.0% 67.1%
2m3lA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.81 72.0 6.46e-01 100.0% 72.4%
3nw0A03 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.64 34.0 3.39e-01 70.9% 46.6%
4n4fA02 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.62 39.0 4.35e-01 76.4% 85.0%
2nutB02 2.30.30.380 Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 0.60 34.0 3.28e-01 72.7% 45.2%
1rfhA01 3.30.60.20 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.60 38.0 4.16e-01 100.0% 85.4%
2lo3A01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.58 29.0 3.60e-01 74.5% 86.2%
1g2rA00 3.30.1230.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › YlxR-like 0.57 43.0 3.63e-01 81.8% 55.3%
5hvqC02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 39.0 3.26e-01 72.7% 51.0%
2drpA02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.55 27.0 3.43e-01 70.9% 75.9%
3vhtB02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.54 30.0 3.55e-01 80.0% 79.4%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 36.0 3.14e-01 72.7% 46.8%
2epcA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.53 28.0 3.29e-01 74.5% 75.8%
3uk2A02 3.30.1300.10 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › Pantoate-beta-alanine ligase, C-terminal domain 0.53 41.0 3.42e-01 87.3% 69.9%
2e6xA00 3.10.20.570 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Protein of unknown function DUF3248 0.53 37.0 3.47e-01 74.5% 97.1%
1lnwF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 39.0 3.04e-01 85.5% 36.3%
8a7dC01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.52 39.0 2.70e-01 83.6% 81.5%
2pjpA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 35.0 3.42e-01 72.7% 65.6%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4802726 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.93 87.0 8.22e-01 100.0% 85.9%
185477 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.93 69.0 6.41e-01 100.0% 64.2%
3036062 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.90 82.0 7.29e-01 100.0% 72.4%
185478 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.86 76.0 7.26e-01 100.0% 86.2%
1734555 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.84 75.0 6.57e-01 100.0% 67.9%
4802727 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.81 71.0 6.62e-01 100.0% 78.6%
3313010 376.1.3.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.66 39.0 4.12e-01 74.5% 66.0%
4021522 376.1.1.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.60 33.0 3.46e-01 72.7% 56.0%
5071927 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.59 37.0 3.76e-01 74.5% 63.6%
3642366 376.1.3.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD 0.57 40.0 3.93e-01 76.4% 66.7%
3428038 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.57 39.0 3.98e-01 87.3% 72.7%
3469416 101.19.1.1 ↗ alpha arrays › HTH › C-terminal subdomain in oxygen-independent coproporphyrinogen III oxidase HemN › C-terminal subdomain in oxygen-independent coproporphyrinogen III oxidase HemN › HemN_C 0.57 44.0 3.57e-01 92.7% 43.8%
3486059 386.1.1.20 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-met 0.57 36.0 3.87e-01 98.2% 87.5%
4055899 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.57 31.0 3.70e-01 90.9% 93.3%
3223233 375.1.1.179 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.57 36.0 2.43e-01 83.6% 15.7%
3764172 386.1.1.250 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PRP21_like_P 0.57 29.0 3.54e-01 76.4% 83.3%
3780237 101.1.2.265 ↗ alpha arrays › HTH › HTH › winged helix domain › Stork_head 0.55 38.0 2.67e-01 72.7% 27.6%
4024651 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.54 33.0 3.23e-01 74.5% 53.3%
864518 386.1.1.39 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-WRNIP1_ubi 0.54 30.0 3.55e-01 80.0% 79.4%
3343296 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 38.0 3.60e-01 89.1% 61.4%
3845634 574.1.1.4 ↗ alpha bundles › Surp module (SWAP domain) › Surp module (SWAP domain) › Surp module (SWAP domain) › PRP21_like_P 0.53 27.0 3.31e-01 74.5% 82.8%
3468275 376.1.3.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.53 35.0 2.92e-01 74.5% 36.9%
3921366 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.52 32.0 2.89e-01 85.5% 42.7%
3594538 2003.1.4.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain 0.52 38.0 2.54e-01 85.5% 35.9%
3688307 108.1.1.98 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_5, EF-hand_7 0.52 41.0 3.00e-01 94.5% 70.1%
3963491 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.51 31.0 3.52e-01 76.4% 85.0%
3816531 376.1.2.2 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › C1_2 0.51 44.0 3.39e-01 100.0% 86.2%
3709137 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.51 28.0 3.02e-01 83.6% 60.0%
2163511 375.1.1.18 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.50 32.0 3.42e-01 94.5% 83.3%
D2 high residues 88-157
PDB
Domain cluster: rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 37.2 4.70e-09 97.1% 60.9%
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2m3lA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.85 72.0 7.06e-01 91.4% 86.8%
2ljxA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.79 65.0 6.17e-01 88.6% 75.6%
2darA01 2.10.110.10 Mainly Beta › Ribbon › Cysteine Rich Protein › Cysteine Rich Protein 0.52 40.0 4.00e-01 84.3% 97.2%
1yt3A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.50 34.0 2.52e-01 70.0% 48.5%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4802727 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.94 86.0 8.63e-01 97.1% 97.1%
1734555 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.91 84.0 7.99e-01 100.0% 86.4%
185478 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.81 67.0 6.99e-01 94.3% 98.5%
3036062 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.77 67.0 6.57e-01 94.3% 86.8%
4802726 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.77 62.0 6.44e-01 87.1% 95.3%
185477 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.68 52.0 5.37e-01 100.0% 85.1%
3763621 221.1.1.42 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › GABP-alpha 0.56 44.0 4.12e-01 87.1% 91.1%
3418697 1.1.11.1 ↗ beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 0.55 43.0 3.92e-01 87.1% 99.0%
4253107 840.1.1.1 ↗ a+b two layers › RPB5-like RNA polymerase subunit › RPB5-like RNA polymerase subunit › RPB5-like RNA polymerase subunit › RNA_pol_Rpb5_C 0.50 42.0 4.18e-01 95.7% 100.0%