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E6

Euk-Vir

Rousettus_aegyptiacus_papillomavirus_1

E6__YP_717907__Rousettus_aegyptiacus_papillomavirus_1__369584

Identity

Accession:
YP_717907 ↗
Protein ID:
E6
Kingdom:
euk

Quality

92.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-65
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 37.7 3.40e-09 69.5% 35.4%
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ljxA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.86 76.0 6.82e-01 100.0% 70.7%
2m3lA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.84 76.0 6.96e-01 100.0% 78.9%
2gviA03 3.30.60.20 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.69 40.0 4.96e-01 79.7% 100.0%
3vd6C01 3.30.50.10 Alpha Beta › 2-Layer Sandwich › Erythroid Transcription Factor GATA-1; Chain A › Erythroid Transcription Factor GATA-1, subunit A 0.69 38.0 4.41e-01 74.6% 78.0%
2zetC00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.68 42.0 3.20e-01 83.1% 26.2%
2gatA00 3.30.50.10 Alpha Beta › 2-Layer Sandwich › Erythroid Transcription Factor GATA-1; Chain A › Erythroid Transcription Factor GATA-1, subunit A 0.67 40.0 3.88e-01 81.4% 53.0%
5d0iB00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.65 36.0 3.87e-01 72.9% 60.8%
3lrqB00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.64 38.0 3.48e-01 76.3% 43.8%
4n4fA02 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.64 39.0 4.57e-01 74.6% 90.0%
4uf0A03 2.10.110.20 Mainly Beta › Ribbon › Cysteine Rich Protein › 0.63 46.0 4.50e-01 98.3% 70.8%
1y8fA00 3.30.60.20 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.62 40.0 4.27e-01 83.1% 76.5%
1rfhA01 3.30.60.20 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.62 40.0 4.43e-01 98.3% 92.7%
2xzmZ00 3.30.1230.20 Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › Ribosomal protein S21 0.57 42.0 3.56e-01 79.7% 54.6%
2epcA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.57 30.0 3.47e-01 76.3% 78.8%
3vhtB02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.55 32.0 3.69e-01 93.2% 94.1%
2luyA01 3.30.60.210 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Stc1 domain 0.55 41.0 4.22e-01 83.1% 93.0%
2nutB02 2.30.30.380 Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 0.55 34.0 3.39e-01 76.3% 58.1%
3hcsA02 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.55 33.0 3.51e-01 88.1% 69.2%
2fclA00 3.30.460.40 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.54 42.0 3.22e-01 89.8% 84.6%
1lnwF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 40.0 3.08e-01 78.0% 37.1%
2ewlA00 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 42.0 4.30e-01 86.4% 87.5%
3goxA03 3.40.1800.10 Alpha Beta › 3-Layer(aba) Sandwich › His-Me finger endonuclease fold › His-Me finger endonucleases 0.54 42.0 3.87e-01 100.0% 64.2%
4r24B00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.54 45.0 4.02e-01 94.9% 72.9%
3szpA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.42e-01 78.0% 83.1%
2l02A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 38.0 3.42e-01 78.0% 58.5%
2cklB01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.51 33.0 3.13e-01 79.7% 50.7%
5hkxA04 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.51 31.0 3.46e-01 74.6% 81.8%
2innB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.51 37.0 2.20e-01 78.0% 9.7%
2esnA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 36.0 3.23e-01 78.0% 58.4%
5dahA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.51 40.0 3.06e-01 91.5% 51.9%
5z4zC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.50 37.0 3.26e-01 79.7% 61.4%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4802726 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.96 89.0 8.66e-01 98.3% 90.6%
185477 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.92 70.0 6.66e-01 100.0% 70.1%
1734555 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.90 83.0 7.39e-01 100.0% 72.8%
3036062 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.87 79.0 7.26e-01 100.0% 77.6%
4802727 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.86 74.0 6.95e-01 93.2% 78.6%
185478 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.86 78.0 7.61e-01 100.0% 90.8%
2755068 376.1.1.12 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING-like 0.74 39.0 4.28e-01 72.9% 62.0%
3638393 376.1.1.27 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_5 0.72 50.0 4.63e-01 100.0% 57.3%
3796016 376.1.3.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.71 42.0 4.35e-01 76.3% 63.6%
3268019 376.1.1.21 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 0.68 42.0 4.09e-01 78.0% 56.9%
3275027 376.1.1.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.68 39.0 3.10e-01 76.3% 29.6%
4021522 376.1.1.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.67 38.0 4.06e-01 74.6% 64.0%
3355343 376.1.1.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.66 38.0 4.09e-01 100.0% 66.0%
3414074 376.1.1.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.66 36.0 3.83e-01 71.2% 60.0%
3366410 376.1.1.21 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 0.64 42.0 3.36e-01 100.0% 33.9%
3518157 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.63 39.0 4.13e-01 81.4% 72.0%
3486059 386.1.1.20 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-met 0.63 41.0 4.52e-01 98.3% 100.0%
4011434 376.1.1.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.61 38.0 3.34e-01 91.5% 40.0%
3394822 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.60 38.0 2.64e-01 76.3% 19.0%
3743391 376.1.3.56 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PF30811 0.59 44.0 3.89e-01 79.7% 55.3%
3468275 376.1.3.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.59 38.0 3.19e-01 76.3% 37.9%
3550392 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 37.0 2.65e-01 79.7% 20.5%
4966035 376.1.3.98 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › DUF7562 0.58 42.0 4.17e-01 76.3% 75.0%
5049661 376.1.2.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain 0.55 34.0 3.71e-01 79.7% 77.8%
3642366 376.1.3.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD 0.55 39.0 3.92e-01 79.7% 75.0%
3485267 376.1.1.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.55 34.0 3.10e-01 79.7% 43.5%
3380148 377.1.1.4 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › GATA 0.54 29.0 3.43e-01 76.3% 80.0%
3517305 376.1.1.23 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4_2 0.54 34.0 2.91e-01 76.3% 38.9%
3275237 376.1.3.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.54 40.0 3.99e-01 83.1% 85.0%
3478140 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.53 29.0 3.05e-01 78.0% 56.0%
3840903 386.1.1.1 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2 0.53 29.0 2.49e-01 78.0% 27.0%
3938245 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.52 37.0 2.55e-01 76.3% 24.8%
4004083 376.1.1.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.52 34.0 2.85e-01 79.7% 37.9%
3223233 375.1.1.179 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.52 37.0 2.50e-01 76.3% 22.6%
3397207 386.1.1.1 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2 0.52 33.0 2.53e-01 91.5% 26.2%
3926105 376.1.3.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD 0.51 40.0 3.66e-01 84.7% 67.5%
3376798 376.1.1.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4 0.51 33.0 3.29e-01 76.3% 63.3%
1247294 375.1.1.18 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.51 32.0 3.39e-01 88.1% 77.1%
3751549 375.1.1.18 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.51 38.0 3.55e-01 96.6% 64.0%
4920017 375.1.1.18 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.50 34.0 3.81e-01 71.2% 95.5%
3634792 376.1.3.27 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf-PHD-like 0.50 42.0 3.82e-01 96.6% 92.9%
D2 high residues 72-131
PDB
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2m3lA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.91 80.0 7.35e-01 96.7% 75.0%
2ljxA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.85 72.0 6.36e-01 91.7% 65.9%
3hhdA01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.56 39.0 2.37e-01 73.3% 66.9%
4bbqA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.56 37.0 3.57e-01 71.7% 58.6%
2gexA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 45.0 3.51e-01 95.0% 78.8%
1yelA00 2.40.330.10 Mainly Beta › Beta Barrel › At1g16640 B3 domain › DNA-binding pseudobarrel domain 0.54 45.0 3.90e-01 98.3% 89.2%
1m32A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.54 42.0 2.89e-01 90.0% 96.3%
1sqhA02 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.54 43.0 3.41e-01 98.3% 42.0%
4orlA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 41.0 3.50e-01 88.3% 90.9%
4i1kA00 2.40.330.10 Mainly Beta › Beta Barrel › At1g16640 B3 domain › DNA-binding pseudobarrel domain 0.53 41.0 3.50e-01 95.0% 78.8%
2k54A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 42.0 3.44e-01 93.3% 83.7%
3f40A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 37.0 3.25e-01 81.7% 83.8%
2r4iA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 37.0 3.07e-01 80.0% 88.6%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 35.0 3.12e-01 73.3% 51.1%
3iwgA01 3.40.630.80 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › 0.51 40.0 3.23e-01 96.7% 42.3%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1734555 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.92 83.0 7.41e-01 100.0% 71.6%
185478 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.91 81.0 7.87e-01 95.0% 87.7%
4802727 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.87 80.0 7.54e-01 100.0% 88.6%
4802726 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.83 69.0 6.75e-01 91.7% 84.4%
3036062 4255.1.1.1 few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.78 70.0 6.41e-01 100.0% 77.6%
3164830 377.1.1.7 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › zf-dskA_traR 0.66 36.0 4.20e-01 83.3% 77.5%
3239460 376.1.3.1 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD 0.58 35.0 3.66e-01 70.0% 65.5%
3346108 1.1.11.0 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain 0.58 48.0 3.93e-01 100.0% 73.6%
3418697 1.1.11.1 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 0.53 42.0 3.70e-01 93.3% 94.9%
5015075 221.12.1.0 a+b two layers › beta-Grasp 0.53 42.0 4.29e-01 91.7% 100.0%
3417387 1.1.11.1 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 0.53 41.0 3.56e-01 91.7% 82.9%
2117616 376.1.3.0 few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger 0.51 35.0 3.52e-01 86.7% 74.6%
3586667 102.1.1.150 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › Plectin 0.50 37.0 3.40e-01 83.3% 84.7%