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E6_protein
Euk-VirMustela_putorius_papillomavirus_1
E6_protein__YP_008519308__Mustela_putorius_papillomavirus_1__2259540
Identity
- Accession:
- YP_008519308 ↗
- Protein ID:
- E6_protein
- Kingdom:
- euk
Quality
84.6
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Taupapillomavirus›
Mustela_putorius_papillomavirus_1
TaxID: 2259540
Cluster
View cluster (138 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 8-90
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 31.6 | 2.70e-07 | 41.0% | 30.9% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.80 | 57.0 | 5.93e-01 | 100.0% | 80.3% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.80 | 59.0 | 5.95e-01 | 98.8% | 78.0% |
| 4n4fA02 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.60 | 28.0 | 3.54e-01 | 94.0% | 82.5% |
| 2byvE05 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.56 | 41.0 | 4.16e-01 | 96.4% | 81.0% |
| 2ylmA03 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.54 | 45.0 | 4.34e-01 | 96.4% | 85.6% |
| 1s6lA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 33.0 | 3.96e-01 | 91.6% | 98.1% |
| 2j3lA03 | 3.90.960.10 | Alpha Beta › Alpha-Beta Complex › YbaK protein › YbaK/aminoacyl-tRNA synthetase-associated domain | 0.52 | 43.0 | 3.58e-01 | 90.4% | 97.3% |
| 1ltlA03 | 2.20.28.10 | Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › | 0.51 | 30.0 | 3.69e-01 | 94.0% | 98.0% |
| 5kc8A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.51 | 43.0 | 3.15e-01 | 95.2% | 60.2% |
| 4chkB00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.50 | 41.0 | 3.99e-01 | 95.2% | 82.4% |
| 1wh2A01 | 3.30.1490.40 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › GYF domain | 0.50 | 31.0 | 3.49e-01 | 80.7% | 85.2% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3607227 | 4012.3.1.0 ↗ | a+b two layers › SSHS domain › SSHS domain in CRISPR-associated endonuclease Cas9 › SSHS domain in CRISPR-associated endonuclease Cas9 | 0.62 | 36.0 | 4.32e-01 | 92.8% | 94.0% |
| 3517465 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.54 | 43.0 | 4.40e-01 | 94.0% | 93.8% |
| 3216855 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.53 | 44.0 | 4.02e-01 | 96.4% | 77.5% |
| 2759971 | 376.1.1.37 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › SLX1_C | 0.52 | 28.0 | 2.78e-01 | 83.1% | 44.0% |
| 5010420 | 2492.1.1.0 ↗ | a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like | 0.52 | 37.0 | 3.50e-01 | 78.3% | 82.4% |
D2
high
residues 98-169
Domain cluster:
rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 39.6 | 8.80e-10 | 94.4% | 51.8% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.91 | 78.0 | 7.63e-01 | 90.3% | 86.8% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.82 | 67.0 | 6.38e-01 | 87.5% | 76.8% |
| 2juoA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 42.0 | 4.00e-01 | 90.3% | 100.0% |
| 1c48A00 | 2.40.50.70 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.53 | 41.0 | 4.22e-01 | 86.1% | 98.6% |
| 2darA01 | 2.10.110.10 | Mainly Beta › Ribbon › Cysteine Rich Protein › Cysteine Rich Protein | 0.53 | 40.0 | 4.01e-01 | 81.9% | 97.2% |
| 3en8A01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.52 | 37.0 | 3.31e-01 | 77.8% | 88.4% |
| 4orlA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 37.0 | 3.28e-01 | 77.8% | 90.0% |
| 5x2bD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 38.0 | 2.64e-01 | 83.3% | 83.3% |
| 7jw2A01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.51 | 34.0 | 2.54e-01 | 70.8% | 54.3% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.95 | 86.0 | 8.79e-01 | 95.8% | 98.6% |
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.94 | 89.0 | 8.52e-01 | 100.0% | 88.9% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.87 | 73.0 | 7.72e-01 | 93.1% | 100.0% |
| 4802726 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.86 | 70.0 | 7.36e-01 | 86.1% | 96.9% |
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.80 | 69.0 | 6.83e-01 | 93.1% | 88.2% |
| 185477 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.70 | 54.0 | 5.57e-01 | 98.6% | 86.6% |
| 3763621 | 221.1.1.42 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › GABP-alpha | 0.54 | 42.0 | 4.00e-01 | 87.5% | 90.0% |
| 5015075 | 221.12.1.0 ↗ | a+b two layers › beta-Grasp | 0.51 | 36.0 | 3.78e-01 | 76.4% | 100.0% |
| 2605238 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.50 | 43.0 | 3.82e-01 | 97.2% | 99.1% |