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E6_protein
Euk-VirMesocricetus_auratus_papillomavirus_1
E6_protein__YP_008720071__Mesocricetus_auratus_papillomavirus_1__1408129
Identity
- Accession:
- YP_008720071 ↗
- Protein ID:
- E6_protein
- Kingdom:
- euk
Quality
92.5
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Pipapillomavirus›
Mesocricetus_auratus_papillomavirus_1
TaxID: 1408129
Cluster
View cluster (138 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-58
Domain cluster:
rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.85 | 75.0 | 6.73e-01 | 100.0% | 71.1% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.84 | 74.0 | 6.48e-01 | 100.0% | 65.9% |
| 4n4fA02 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.61 | 36.0 | 3.98e-01 | 74.1% | 77.5% |
| 1x1aA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 42.0 | 2.94e-01 | 90.7% | 24.9% |
| 1lnwF01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 42.0 | 3.22e-01 | 88.9% | 37.9% |
| 4ru1A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.52 | 36.0 | 2.76e-01 | 98.1% | 27.7% |
| 1y0uA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 39.0 | 3.30e-01 | 88.9% | 49.4% |
| 4qf3A00 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.52 | 31.0 | 3.07e-01 | 83.3% | 52.6% |
| 3vhtB02 | 3.30.160.60 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger | 0.51 | 28.0 | 3.25e-01 | 77.8% | 70.6% |
| 3ke7B00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 39.0 | 3.16e-01 | 94.4% | 75.9% |
| 4nwbA02 | 3.90.105.20 | Alpha Beta › Alpha-Beta Complex › Molybdopterin biosynthesis moea protein, domain 2 › Ribosomal protein L10, N-terminal fragment, domain II | 0.51 | 34.0 | 2.97e-01 | 70.4% | 76.7% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.93 | 86.0 | 7.35e-01 | 100.0% | 66.7% |
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.89 | 81.0 | 7.37e-01 | 100.0% | 77.1% |
| 4802726 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.85 | 75.0 | 7.10e-01 | 100.0% | 84.4% |
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.84 | 75.0 | 6.66e-01 | 100.0% | 71.1% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.81 | 72.0 | 6.79e-01 | 100.0% | 84.6% |
| 185477 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.78 | 61.0 | 5.67e-01 | 98.1% | 67.2% |
| 4983247 | 242.2.1.2 ↗ | a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N | 0.64 | 45.0 | 3.71e-01 | 75.9% | 77.0% |
| 3486059 | 386.1.1.20 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-met | 0.62 | 37.0 | 4.00e-01 | 94.4% | 77.5% |
| 3509728 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.60 | 43.0 | 4.37e-01 | 100.0% | 76.4% |
| 3602143 | 3755.3.1.305 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook | 0.59 | 36.0 | 2.38e-01 | 75.9% | 13.8% |
| 3428038 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.58 | 38.0 | 3.81e-01 | 74.1% | 65.5% |
| 5064397 | 5086.1.1.231 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook | 0.57 | 36.0 | 2.50e-01 | 74.1% | 17.4% |
| 5014330 | 148.1.3.402 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Rad50_zn_hook | 0.56 | 37.0 | 2.98e-01 | 75.9% | 34.5% |
| 3251626 | 376.1.1.22 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-C3HC4_3 | 0.55 | 31.0 | 2.80e-01 | 70.4% | 37.3% |
| 5047150 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 37.0 | 2.55e-01 | 75.9% | 19.5% |
| 3539459 | 386.1.1.3 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-TRAF | 0.53 | 30.0 | 3.15e-01 | 83.3% | 54.0% |
| 4988993 | 5086.1.1.231 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook | 0.53 | 36.0 | 2.64e-01 | 75.9% | 25.3% |
| 3960172 | 243.1.1.18 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 | 0.53 | 41.0 | 3.34e-01 | 92.6% | 93.2% |
| 4352411 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.52 | 30.0 | 3.13e-01 | 88.9% | 58.0% |
| 3348294 | 386.1.1.3 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-TRAF | 0.51 | 31.0 | 3.19e-01 | 85.2% | 62.0% |
| 3796016 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.51 | 34.0 | 3.47e-01 | 74.1% | 69.1% |
| 3922396 | 386.1.1.3 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-TRAF | 0.51 | 29.0 | 3.17e-01 | 88.9% | 64.4% |
| 3568338 | 386.1.1.44 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf_UBZ | 0.51 | 25.0 | 3.28e-01 | 74.1% | 88.0% |
| 3468275 | 376.1.3.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger | 0.51 | 34.0 | 2.84e-01 | 72.2% | 36.9% |
| 3926652 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.50 | 39.0 | 3.42e-01 | 94.4% | 70.5% |
D2
high
residues 66-129
Domain cluster:
rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 42.7 | 9.80e-11 | 100.0% | 56.4% |