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E6_protein
Euk-VirSus_scrofa_papillomavirus_2
E6_protein__YP_009408610__Sus_scrofa_papillomavirus_2__2025338
Identity
- Accession:
- YP_009408610 ↗
- Protein ID:
- E6_protein
- Kingdom:
- euk
Quality
94.5
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Sus_scrofa_papillomavirus_2
TaxID: 2025338
Cluster
View cluster (138 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-62
Domain cluster:
rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 31.0 | 4.00e-07 | 67.9% | 35.4% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2m3lA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.84 | 75.0 | 6.78e-01 | 100.0% | 77.6% |
| 2ljxA00 | 3.30.240.40 | Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein | 0.84 | 75.0 | 6.59e-01 | 100.0% | 69.5% |
| 2ds5A00 | 6.20.220.10 | Special › Other non-globular › Erythroid Transcription Factor GATA-1; Chain A › ClpX chaperone, C4-type zinc finger domain | 0.66 | 40.0 | 4.37e-01 | 76.8% | 76.7% |
| 2d8yA01 | 2.10.110.10 | Mainly Beta › Ribbon › Cysteine Rich Protein › Cysteine Rich Protein | 0.64 | 44.0 | 4.07e-01 | 100.0% | 55.6% |
| 3vd6C01 | 3.30.50.10 | Alpha Beta › 2-Layer Sandwich › Erythroid Transcription Factor GATA-1; Chain A › Erythroid Transcription Factor GATA-1, subunit A | 0.60 | 35.0 | 3.91e-01 | 73.2% | 75.6% |
| 1x4wA00 | 4.10.1110.10 | Few Secondary Structures › Irregular › Zf-an1 domain › AN1-like Zinc finger | 0.59 | 37.0 | 3.53e-01 | 75.0% | 50.7% |
| 1y8fA00 | 3.30.60.20 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › | 0.59 | 39.0 | 4.12e-01 | 100.0% | 76.5% |
| 2luyA01 | 3.30.60.210 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Stc1 domain | 0.59 | 44.0 | 4.45e-01 | 83.9% | 91.2% |
| 2nutB02 | 2.30.30.380 | Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 | 0.58 | 36.0 | 3.51e-01 | 76.8% | 56.5% |
| 2xzmZ00 | 3.30.1230.20 | Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › Ribosomal protein S21 | 0.56 | 41.0 | 3.42e-01 | 78.6% | 51.5% |
| 1lnwF01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 42.0 | 3.17e-01 | 80.4% | 36.3% |
| 7bqjA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 39.0 | 3.47e-01 | 80.4% | 54.3% |
| 1in4A02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 40.0 | 3.65e-01 | 80.4% | 63.0% |
| 5tdrA00 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.53 | 33.0 | 3.11e-01 | 94.6% | 47.1% |
| 1bjaA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 38.0 | 3.22e-01 | 80.4% | 48.4% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4802726 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.96 | 91.0 | 8.64e-01 | 100.0% | 89.1% |
| 1734555 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.88 | 80.0 | 7.04e-01 | 100.0% | 70.4% |
| 185477 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.87 | 66.0 | 6.20e-01 | 100.0% | 67.2% |
| 3036062 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.87 | 79.0 | 7.07e-01 | 100.0% | 75.0% |
| 185478 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.86 | 78.0 | 7.41e-01 | 100.0% | 89.2% |
| 4802727 | 4255.1.1.1 ↗ | few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 | 0.83 | 72.0 | 6.68e-01 | 96.4% | 78.6% |
| 2755068 | 376.1.1.12 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING-like | 0.71 | 38.0 | 4.00e-01 | 71.4% | 58.0% |
| 3244851 | 376.1.1.20 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_UBOX | 0.64 | 37.0 | 3.06e-01 | 75.0% | 33.7% |
| 3743391 | 376.1.3.56 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PF30811 | 0.61 | 45.0 | 3.88e-01 | 78.6% | 51.8% |
| 3642366 | 376.1.3.1 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD | 0.59 | 43.0 | 4.24e-01 | 78.6% | 75.0% |
| 3483078 | 226.1.1.1 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain › BTB | 0.57 | 41.0 | 3.45e-01 | 78.6% | 74.0% |
| 3889001 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.56 | 38.0 | 4.18e-01 | 71.4% | 100.0% |
| 3736936 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.55 | 38.0 | 3.38e-01 | 76.8% | 76.8% |
| None | — | 0.55 | 46.0 | 4.11e-01 | 98.2% | 74.1% | |
| 4018018 | 376.1.1.21 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 | 0.54 | 47.0 | 3.87e-01 | 100.0% | 62.1% |
D2
high
residues 67-127
Domain cluster:
rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00518.23 best | E6 | 35.3 | 1.90e-08 | 98.4% | 44.5% |