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E6_protein

Euk-Vir

Rodent_papillomavirus

E6_protein__YP_009552130__Rodent_papillomavirus__2050020

Identity

Accession:
YP_009552130 ↗
Protein ID:
E6_protein
Kingdom:
euk

Quality

93.4 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Rodent_papillomavirus

TaxID: 2050020

Cluster

View cluster (138 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-60
PDB
Domain cluster: rep: putative_E6_protein__YP_008574810__Felis_catus_papillomavirus_4__1398507__D7-59
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ljxA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.85 76.0 6.65e-01 100.0% 67.1%
2m3lA00 3.30.240.40 Alpha Beta › 2-Layer Sandwich › CRO Repressor › E6 early regulatory protein 0.82 73.0 6.54e-01 100.0% 72.4%
2w0tA00 3.30.60.160 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.64 37.0 4.02e-01 89.1% 69.8%
2gviA03 3.30.60.20 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.62 34.0 4.06e-01 74.5% 85.3%
4n4fA02 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.60 36.0 3.97e-01 74.5% 80.0%
4bbqA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.58 43.0 4.09e-01 89.1% 65.7%
3purA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.58 40.0 3.68e-01 87.3% 54.1%
1wdvA00 3.90.960.10 Alpha Beta › Alpha-Beta Complex › YbaK protein › YbaK/aminoacyl-tRNA synthetase-associated domain 0.57 51.0 3.70e-01 100.0% 84.7%
6oinA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 42.0 3.96e-01 89.1% 65.7%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 40.0 3.40e-01 76.4% 51.1%
1zavA01 3.30.70.1730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain 0.56 37.0 2.95e-01 70.9% 67.4%
3hcsA02 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.56 33.0 3.38e-01 85.5% 59.6%
3vhtB02 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.55 28.0 3.31e-01 89.1% 67.6%
1wevA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.54 37.0 3.55e-01 80.0% 62.5%
2c60A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 41.0 3.74e-01 87.3% 98.7%
3goxA03 3.40.1800.10 Alpha Beta › 3-Layer(aba) Sandwich › His-Me finger endonuclease fold › His-Me finger endonucleases 0.53 39.0 3.44e-01 100.0% 53.1%
2qh5B00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.52 41.0 2.70e-01 89.1% 19.1%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.52 35.0 2.85e-01 74.5% 36.9%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 35.0 2.99e-01 76.4% 37.6%
4ru1A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 35.0 2.72e-01 96.4% 27.7%
5dahA01 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.52 37.0 2.90e-01 85.5% 92.2%
1stzA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 35.0 3.15e-01 74.5% 78.8%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 34.0 2.91e-01 76.4% 37.7%
4r24B00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.50 37.0 3.18e-01 90.9% 50.6%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1734555 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.88 79.0 6.93e-01 100.0% 67.9%
4802726 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.86 77.0 7.32e-01 100.0% 85.9%
3036062 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.86 76.0 6.86e-01 100.0% 72.4%
4802727 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.84 75.0 6.90e-01 100.0% 78.6%
185477 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.81 65.0 6.00e-01 98.2% 68.7%
185478 4255.1.1.1 ↗ few secondary structure elements › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 C-terminal domain-like › E6 0.79 69.0 6.60e-01 100.0% 86.2%
3164830 377.1.1.7 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like › zf-dskA_traR 0.64 40.0 4.38e-01 94.5% 85.0%
3882708 386.1.1.48 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf_C2HC_14 0.64 31.0 3.74e-01 78.2% 68.6%
3955689 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.63 44.0 3.72e-01 74.5% 83.0%
3509728 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.62 44.0 4.41e-01 100.0% 74.5%
4983247 242.2.1.2 ↗ a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.61 42.0 3.50e-01 74.5% 77.0%
4298719 376.1.1.37 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › SLX1_C 0.60 39.0 3.22e-01 83.6% 36.0%
3486059 386.1.1.20 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-met 0.60 36.0 3.95e-01 94.5% 80.0%
3609869 1189.1.1.1 ↗ alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop 0.59 40.0 2.55e-01 74.5% 80.9%
4003986 375.1.1.186 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › NOA36 0.58 35.0 3.88e-01 78.2% 79.1%
4996914 242.2.1.2 ↗ a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.56 39.0 3.37e-01 74.5% 85.6%
3469416 101.19.1.1 ↗ alpha arrays › HTH › C-terminal subdomain in oxygen-independent coproporphyrinogen III oxidase HemN › C-terminal subdomain in oxygen-independent coproporphyrinogen III oxidase HemN › HemN_C 0.56 45.0 3.75e-01 94.5% 48.6%
5065972 242.2.1.2 ↗ a+b two layers › Homing endonucleases-like › tRNA-intron endonuclease N-terminal domain-like › tRNA-intron endonuclease N-terminal domain-like › tRNA_int_endo_N 0.56 39.0 3.56e-01 74.5% 90.7%
864518 386.1.1.39 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-WRNIP1_ubi 0.55 28.0 3.31e-01 89.1% 67.6%
3938245 375.1.1.179 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha 0.55 43.0 2.88e-01 85.5% 27.1%
3239460 376.1.3.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD 0.55 36.0 3.69e-01 80.0% 70.9%
4352411 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.55 31.0 3.25e-01 83.6% 58.0%
4300868 865.1.1.0 ↗ beta complex topology › PheT/TilS domain › PheT/TilS domain › PheT/TilS domain 0.54 37.0 2.69e-01 76.4% 64.1%
3882461 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.53 43.0 3.97e-01 92.7% 73.3%
3348295 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.53 26.0 3.19e-01 74.5% 70.0%
3270487 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.53 35.0 2.96e-01 76.4% 35.5%
3922396 386.1.1.3 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-TRAF 0.53 31.0 3.32e-01 83.6% 66.7%
4679870 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.52 40.0 3.40e-01 89.1% 50.5%
3751549 375.1.1.18 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 0.52 37.0 3.51e-01 100.0% 61.3%
3843654 386.1.1.112 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2HC_2 0.51 26.0 2.78e-01 74.5% 50.0%
5041978 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.51 35.0 3.65e-01 74.5% 93.3%
4013317 101.1.2.359 ↗ alpha arrays › HTH › HTH › winged helix domain › GPIID_WHD 0.50 39.0 2.88e-01 89.1% 66.9%
3586667 102.1.1.150 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › Plectin 0.50 38.0 3.45e-01 90.9% 80.0%
D2 high residues 68-130
PDB
Domain cluster: rep: E6__YP_009177725__Trichechus_manatus_latirostris_papillomavirus_4__2848317__D98-164
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00518.23 best E6 34.7 2.90e-08 98.4% 51.8%