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E70
Euk-VirMurid_betaherpesvirus_8
E70__YP_007016467__Murid_betaherpesvirus_8__1261657
Identity
- Accession:
- YP_007016467 ↗
- Protein ID:
- E70
- Kingdom:
- euk
Quality
88.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Muromegalovirus›
Murid_betaherpesvirus_8
TaxID: 1261657
Cluster
View cluster (58 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 479-550_567-702
Domain cluster:
rep: primase__YP_009345453__Noumeavirus__1955558__D12-194
D2
high
residues 728-738_762-877
Domain cluster:
rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03121.21 best | Herpes_UL52 | 74.2 | 8.60e-21 | 60.6% | 96.0% |
D3
medium
residues 1-135
D4
medium
residues 136-217
Domain cluster:
rep: helicase_primase_complex__NP_050224__Human_betaherpesvirus_6B__32604__D142-241
D5
medium
residues 218-274
Domain cluster:
representative
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.74 | 64.0 | 5.54e-01 | 100.0% | 63.0% |
| 3dd9D02 | 6.10.140.2060 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 49.0 | 5.29e-01 | 78.9% | 100.0% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 53.0 | 4.14e-01 | 84.2% | 43.4% |
| 3zdmB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.67 | 43.0 | 4.58e-01 | 70.2% | 76.0% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.66 | 49.0 | 3.61e-01 | 78.9% | 32.7% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.65 | 49.0 | 4.82e-01 | 80.7% | 77.0% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.65 | 49.0 | 3.99e-01 | 82.5% | 43.1% |
| 4ofzA01 | 1.20.58.1800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 46.0 | 3.81e-01 | 87.7% | 40.7% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.63 | 43.0 | 2.98e-01 | 71.9% | 21.6% |
| 4jfcA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.62 | 47.0 | 4.81e-01 | 82.5% | 96.4% |
| 1s5jA04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.62 | 42.0 | 4.17e-01 | 71.9% | 65.6% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 51.0 | 3.92e-01 | 96.5% | 37.4% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.62 | 49.0 | 4.56e-01 | 96.5% | 67.6% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 49.0 | 4.56e-01 | 89.5% | 82.2% |
| 2ptfB02 | 1.20.58.290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. | 0.61 | 41.0 | 4.13e-01 | 75.4% | 68.4% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.61 | 48.0 | 4.28e-01 | 89.5% | 65.9% |
| 2vx2G02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.60 | 47.0 | 4.81e-01 | 87.7% | 100.0% |
| 1q2lA04 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.60 | 48.0 | 3.32e-01 | 94.7% | 49.1% |
| 1zkdA03 | 6.10.250.3300 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.60 | 38.0 | 4.16e-01 | 70.2% | 86.0% |
| 4gouA01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.59 | 42.0 | 3.17e-01 | 75.4% | 29.7% |
| 3rx6A00 | 1.20.58.1090 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer | 0.59 | 48.0 | 3.39e-01 | 91.2% | 29.9% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.59 | 48.0 | 3.99e-01 | 91.2% | 54.9% |
| 4fzwA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.59 | 45.0 | 4.56e-01 | 87.7% | 96.6% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.58 | 49.0 | 4.69e-01 | 96.5% | 82.4% |
| 4nv0A02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.57 | 46.0 | 4.11e-01 | 89.5% | 72.0% |
| 3qxzA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.57 | 49.0 | 4.87e-01 | 98.2% | 96.7% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.57 | 39.0 | 3.97e-01 | 73.7% | 98.2% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 3.83e-01 | 87.7% | 60.9% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.55 | 46.0 | 4.61e-01 | 96.5% | 91.4% |
| 5c9gA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.53 | 41.0 | 4.12e-01 | 87.7% | 87.7% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 44.0 | 3.74e-01 | 100.0% | 58.8% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3715873 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.82 | 61.0 | 6.06e-01 | 86.0% | 76.7% |
| 4541657 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.75 | 66.0 | 5.90e-01 | 100.0% | 75.0% |
| 2593949 | 3833.1.1.0 ↗ | alpha complex topology › TcA alpha-helical shell domain › TcA alpha-helical shell domain › TcA alpha-helical shell domain | 0.72 | 48.0 | 4.98e-01 | 78.9% | 76.5% |
| 4097490 | 3755.1.1.23 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › CemA | 0.70 | 58.0 | 4.72e-01 | 96.5% | 47.8% |
| 4140524 | 604.11.1.1 ↗ | alpha bundles › Spectrin repeat-like › XseB-like › XseB-like › Exonuc_VII_S | 0.70 | 50.0 | 4.98e-01 | 77.2% | 78.3% |
| 4396464 | 605.1.1.305 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Exonuc_VII_S | 0.69 | 50.0 | 4.98e-01 | 77.2% | 75.0% |
| 4354962 | 3390.1.1.0 ↗ | extended segments › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT › Photosystem II reaction center protein T, PsbT | 0.69 | 49.0 | 5.16e-01 | 73.7% | 86.0% |
| 4346136 | 605.1.1.108 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › GrpE | 0.68 | 58.0 | 5.57e-01 | 96.5% | 86.2% |
| 4972595 | 102.1.1.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like | 0.65 | 49.0 | 4.18e-01 | 87.7% | 49.5% |
| 3714091 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.64 | 47.0 | 4.33e-01 | 78.9% | 89.3% |
| 3222941 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.64 | 55.0 | 3.90e-01 | 100.0% | 50.8% |
| 3957419 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.59 | 45.0 | 4.16e-01 | 84.2% | 66.7% |
| 4588595 | 244.1.1.9 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › GMC_oxred_C | 0.57 | 42.0 | 2.92e-01 | 84.2% | 85.8% |
| 5047797 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.55 | 43.0 | 4.02e-01 | 86.0% | 74.7% |
| 3945531 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.53 | 45.0 | 4.29e-01 | 98.2% | 81.4% |
D6
medium
residues 331-478