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E75
Euk-VirMurid_betaherpesvirus_8
E75__YP_007016473__Murid_betaherpesvirus_8__1261657
Identity
- Accession:
- YP_007016473 ↗
- Protein ID:
- E75
- Kingdom:
- euk
Quality
76.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Muromegalovirus›
Murid_betaherpesvirus_8
TaxID: 1261657
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 167-330
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02489.22 best | Herpes_glycop_H | 70.6 | 1.50e-19 | 95.1% | 28.7% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2xqyA01 | 3.30.500.50 | Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › | 0.71 | 60.0 | 5.85e-01 | 98.8% | 80.9% |
| 4exrA01 | 3.10.450.40 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.67 | 26.0 | 3.62e-01 | 92.1% | 70.4% |
| 1vmgA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.67 | 30.0 | 4.24e-01 | 93.3% | 85.4% |
| 2bs6A01 | 2.40.128.190 | Mainly Beta › Beta Barrel › Lipocalin › | 0.58 | 27.0 | 3.60e-01 | 91.5% | 83.3% |
| 3rbyA02 | 2.40.128.310 | Mainly Beta › Beta Barrel › Lipocalin › Protein HRI1, C-terminal domain | 0.55 | 32.0 | 3.96e-01 | 86.6% | 94.7% |
| 3w9kA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 36.0 | 3.93e-01 | 94.5% | 85.2% |
| 3ge2A00 | 2.40.128.50 | Mainly Beta › Beta Barrel › Lipocalin › | 0.52 | 27.0 | 3.51e-01 | 84.8% | 88.8% |
| 1wqsA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.52 | 24.0 | 3.44e-01 | 73.8% | 98.6% |
| 1nkgA01 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.51 | 43.0 | 3.71e-01 | 89.0% | 83.3% |
| 3dxpA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.51 | 28.0 | 3.50e-01 | 77.4% | 90.3% |
| 4wovA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.51 | 24.0 | 3.33e-01 | 78.7% | 88.1% |
| 2qziA00 | 3.40.1720.10 | Alpha Beta › 3-Layer(aba) Sandwich › Streptococcus thermophilus LMG 18311 protein like › Streptococcus thermophilus LMG 18311 protein like | 0.51 | 26.0 | 3.33e-01 | 90.9% | 81.2% |
| 1i36A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 27.0 | 3.35e-01 | 75.6% | 82.8% |
| 1wzaA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.50 | 25.0 | 3.54e-01 | 86.6% | 100.0% |
| 2w4oA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.50 | 24.0 | 3.30e-01 | 88.4% | 93.5% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2095503 | 3146.1.1.1 ↗ | a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H | 0.88 | 85.0 | 5.68e-01 | 100.0% | 31.4% |
| 3267978 | 331.3.1.4 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › IP_trans | 0.59 | 45.0 | 3.80e-01 | 79.3% | 91.6% |
| 3596085 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.53 | 27.0 | 3.76e-01 | 81.7% | 100.0% |
| 5019195 | 12.3.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich | 0.53 | 44.0 | 3.87e-01 | 87.8% | 77.1% |
| 3584281 | 12.3.1.13 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C | 0.52 | 41.0 | 3.35e-01 | 82.3% | 80.7% |
| 3733356 | 298.1.1.25 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › ox_reductase_C | 0.52 | 32.0 | 3.24e-01 | 85.4% | 61.2% |
| 2027 | 12.3.1.17 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › RhgB_N | 0.51 | 43.0 | 3.72e-01 | 89.0% | 83.6% |
| 3223040 | 12.3.1.13 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C | 0.51 | 41.0 | 3.48e-01 | 82.9% | 88.2% |
| 4008120 | 5.1.5.139 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DUF1481 | 0.51 | 34.0 | 3.93e-01 | 87.2% | 92.5% |
D2
high
residues 550-681
Domain cluster:
rep: envelope_glycoprotein_H__NP_077452__Cercopithecine_alphaherpesvirus_9__35246__D674-695_717-808
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17488.8 best | Herpes_glycoH_C | 119.2 | 1.60e-34 | 99.2% | 90.1% |
D3
medium
residues 47-108
D4
medium
residues 113-145_375-402
D5
medium
residues 403-469
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02489.22 best | Herpes_glycop_H | 29.9 | 3.30e-07 | 100.0% | 14.0% |
CATH (52)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7qocA01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.76 | 67.0 | 4.89e-01 | 100.0% | 43.3% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 64.0 | 5.95e-01 | 98.5% | 97.6% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.74 | 63.0 | 5.67e-01 | 97.0% | 95.8% |
| 4ga0A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.73 | 53.0 | 4.16e-01 | 94.0% | 36.4% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.73 | 62.0 | 5.25e-01 | 97.0% | 68.1% |
| 4agsB04 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.73 | 62.0 | 5.00e-01 | 97.0% | 61.7% |
| 5o5jT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.72 | 61.0 | 5.70e-01 | 95.5% | 81.2% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 51.0 | 5.03e-01 | 74.6% | 76.1% |
| 2v0cA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.71 | 60.0 | 4.55e-01 | 94.0% | 44.0% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.71 | 59.0 | 5.07e-01 | 95.5% | 75.9% |
| 2ntxA01 | 1.20.58.2010 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 | 0.71 | 61.0 | 4.35e-01 | 98.5% | 50.5% |
| 3kflA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.71 | 60.0 | 4.42e-01 | 94.0% | 48.0% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 56.0 | 4.93e-01 | 89.6% | 84.2% |
| 5hb0D01 | 1.20.120.1880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleoporin, helical C-terminal domain | 0.70 | 58.0 | 3.94e-01 | 94.0% | 27.5% |
| 8amzP01 | 1.25.40.570 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.69 | 54.0 | 3.42e-01 | 88.1% | 16.3% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.69 | 59.0 | 5.11e-01 | 98.5% | 71.7% |
| 4qreA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.69 | 58.0 | 4.31e-01 | 94.0% | 49.7% |
| 2wzkA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.68 | 56.0 | 4.56e-01 | 91.0% | 92.1% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 46.0 | 4.87e-01 | 71.6% | 86.2% |
| 3iqtA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.68 | 59.0 | 4.95e-01 | 98.5% | 72.8% |
| 3teqB00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 48.0 | 4.24e-01 | 76.1% | 97.0% |
| 4epzA00 | 1.25.40.810 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ | 0.67 | 55.0 | 4.29e-01 | 92.5% | 64.9% |
| 1rqgA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.67 | 56.0 | 4.32e-01 | 94.0% | 56.3% |
| 2au3A04 | 1.20.50.30 | Mainly Alpha › Up-down Bundle › Pheromone ER-1 › | 0.67 | 44.0 | 4.74e-01 | 80.6% | 83.6% |
| 2pftA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.67 | 57.0 | 3.41e-01 | 100.0% | 17.0% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 52.0 | 4.42e-01 | 86.6% | 67.3% |
| 3au4A01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.66 | 54.0 | 3.91e-01 | 94.0% | 31.1% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 53.0 | 5.18e-01 | 92.5% | 90.7% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.66 | 46.0 | 4.48e-01 | 74.6% | 77.6% |
| 1e52A00 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.65 | 42.0 | 4.49e-01 | 70.1% | 80.4% |
| 3nb2A02 | 1.25.40.300 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Putative secreted effector protein | 0.65 | 54.0 | 4.16e-01 | 100.0% | 40.6% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.64 | 53.0 | 4.49e-01 | 95.5% | 64.5% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.64 | 54.0 | 5.03e-01 | 95.5% | 75.3% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 45.0 | 3.74e-01 | 74.6% | 46.8% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 50.0 | 4.90e-01 | 88.1% | 97.3% |
| 2yb5F01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.64 | 54.0 | 5.06e-01 | 97.0% | 76.7% |
| 4hkaA02 | 1.10.287.3810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 41.0 | 4.51e-01 | 71.6% | 86.3% |
| 6axgA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.63 | 52.0 | 4.79e-01 | 94.0% | 73.0% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 50.0 | 4.93e-01 | 94.0% | 89.3% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 51.0 | 4.62e-01 | 94.0% | 75.3% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 50.0 | 4.83e-01 | 92.5% | 85.7% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 49.0 | 4.23e-01 | 89.6% | 73.7% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.62 | 42.0 | 4.20e-01 | 70.1% | 95.6% |
| 3m9vA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 48.0 | 3.73e-01 | 86.6% | 58.6% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.61 | 47.0 | 4.31e-01 | 88.1% | 71.0% |
| 2a9uA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 50.0 | 4.23e-01 | 100.0% | 58.7% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.59 | 49.0 | 4.48e-01 | 98.5% | 89.7% |
| 2zt5A02 | 3.30.40.230 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.57 | 38.0 | 3.63e-01 | 70.1% | 63.1% |
| 3r2cA00 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.57 | 46.0 | 3.69e-01 | 92.5% | 44.2% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 41.0 | 4.41e-01 | 83.6% | 98.2% |
| 2oxlA00 | 1.20.5.5260 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.54 | 38.0 | 3.99e-01 | 79.1% | 83.9% |
| 4aidA02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.51 | 41.0 | 3.91e-01 | 92.5% | 97.6% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4983683 | 604.12.1.140 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF447_C | 0.79 | 63.0 | 6.40e-01 | 86.6% | 98.5% |
| 3185558 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.79 | 65.0 | 4.92e-01 | 100.0% | 38.1% |
| 3498465 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.78 | 65.0 | 5.35e-01 | 94.0% | 68.8% |
| 3581264 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.76 | 67.0 | 5.54e-01 | 100.0% | 78.3% |
| 3224585 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.75 | 62.0 | 5.33e-01 | 94.0% | 82.7% |
| None | — | 0.74 | 59.0 | 3.54e-01 | 88.1% | 12.4% | |
| 3677603 | 109.4.1.359 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C | 0.74 | 64.0 | 3.77e-01 | 97.0% | 12.8% |
| 5068187 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.74 | 49.0 | 4.77e-01 | 71.6% | 62.2% |
| 3740089 | 1134.1.1.7 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 | 0.74 | 57.0 | 5.76e-01 | 89.6% | 86.2% |
| 3184710 | 1134.1.1.7 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 | 0.73 | 64.0 | 6.31e-01 | 95.5% | 91.4% |
| 3416415 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 64.0 | 4.76e-01 | 100.0% | 40.6% |
| 4436109 | 140.1.1.14 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e | 0.73 | 61.0 | 4.59e-01 | 94.0% | 41.8% |
| 3781595 | 1134.1.1.7 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 | 0.69 | 58.0 | 5.82e-01 | 95.5% | 92.9% |
| 3988781 | 604.6.1.63 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF3169 | 0.69 | 56.0 | 4.58e-01 | 94.0% | 80.0% |
| 3384514 | 604.15.1.0 ↗ | alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like | 0.69 | 55.0 | 5.36e-01 | 92.5% | 80.0% |
| 3415464 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.69 | 47.0 | 3.74e-01 | 71.6% | 67.9% |
| 3592737 | 1134.1.1.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain | 0.69 | 57.0 | 5.80e-01 | 95.5% | 95.4% |
| 4012164 | 1134.1.1.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain | 0.69 | 52.0 | 5.33e-01 | 89.6% | 87.7% |
| 3265664 | 4336.1.1.0 ↗ | alpha duplicates or obligate multimers › YheA/YmcA-like › YheA/YmcA-like › YheA/YmcA-like | 0.69 | 47.0 | 4.34e-01 | 73.1% | 68.9% |
| 3321310 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.68 | 58.0 | 4.87e-01 | 98.5% | 81.7% |
| 4872582 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 50.0 | 5.27e-01 | 88.1% | 100.0% |
| 3615321 | 109.4.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 | 0.66 | 56.0 | 3.75e-01 | 100.0% | 47.9% |
| 3614864 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 54.0 | 4.09e-01 | 97.0% | 36.6% |
| 3621994 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 54.0 | 4.42e-01 | 97.0% | 51.9% |
| 4034377 | 4982.1.1.2 ↗ | alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain › RsbU_N | 0.65 | 57.0 | 5.19e-01 | 98.5% | 88.9% |
| 3960659 | 150.8.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE | 0.65 | 44.0 | 3.72e-01 | 71.6% | 62.5% |
| 3879987 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.65 | 46.0 | 4.71e-01 | 92.5% | 78.5% |
| 3903825 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.65 | 50.0 | 4.72e-01 | 92.5% | 68.2% |
| 3909630 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.63 | 46.0 | 4.51e-01 | 91.0% | 70.7% |
| 5083908 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.63 | 51.0 | 4.36e-01 | 95.5% | 61.7% |
| 3409567 | 3755.3.1.324 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 | 0.63 | 43.0 | 3.26e-01 | 71.6% | 31.5% |
| 3504474 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.63 | 45.0 | 4.01e-01 | 77.6% | 89.0% |
| 4326689 | 558.1.1.0 ↗ | alpha duplicates or obligate multimers › Lis-homology dimerization domain › Lis-homology dimerization domain › Lis-homology dimerization domain | 0.61 | 48.0 | 4.20e-01 | 91.0% | 54.5% |
| 3530124 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.61 | 48.0 | 4.60e-01 | 94.0% | 75.0% |
| 3588595 | 101.35.1.4 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 | 0.56 | 42.0 | 4.57e-01 | 86.6% | 100.0% |
| 4850960 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.55 | 46.0 | 3.61e-01 | 97.0% | 76.9% |
D6
medium
residues 470-536
Domain cluster:
rep: UL75__YP_009137470__Papio_ursinus_cytomegalovirus__1667587__D473-538
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02489.22 best | Herpes_glycop_H | 35.6 | 6.20e-09 | 98.5% | 13.8% |
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2es9A00 | 1.20.1290.30 | Mainly Alpha › Up-down Bundle › AhpD-like › | 0.67 | 58.0 | 5.09e-01 | 98.5% | 68.0% |
| 4z7xB00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.65 | 46.0 | 3.24e-01 | 74.6% | 69.7% |
| 4c0eA01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.65 | 53.0 | 3.58e-01 | 95.5% | 30.7% |
| 2w7nA00 | 1.10.10.2690 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.59 | 40.0 | 3.59e-01 | 70.1% | 54.3% |
| 2p0tA02 | 1.10.60.30 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › PSPTO4464-like domains | 0.58 | 38.0 | 3.74e-01 | 98.5% | 62.5% |
| 2kt0A01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.58 | 38.0 | 4.19e-01 | 94.0% | 95.7% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 46.0 | 4.07e-01 | 89.6% | 79.4% |
| 2gh1A02 | 1.10.150.350 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.57 | 45.0 | 3.83e-01 | 85.1% | 75.0% |
| 3dtoA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.57 | 48.0 | 4.41e-01 | 94.0% | 92.0% |
| 1f5qB02 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.56 | 37.0 | 3.04e-01 | 70.1% | 34.1% |
| 3onqA03 | 1.10.10.2840 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain | 0.55 | 43.0 | 3.50e-01 | 85.1% | 76.3% |
| 3d1lA02 | 1.10.1040.20 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › ProC-like, C-terminal domain | 0.55 | 42.0 | 3.74e-01 | 83.6% | 80.8% |
| 3bm1A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.55 | 37.0 | 2.81e-01 | 71.6% | 44.6% |
| 1h1oA02 | 1.10.760.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain | 0.55 | 42.0 | 3.96e-01 | 85.1% | 92.9% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.54 | 46.0 | 4.43e-01 | 95.5% | 89.9% |
| 1oxjA01 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.54 | 41.0 | 4.24e-01 | 88.1% | 88.5% |
| 2blfB01 | 1.10.760.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain | 0.54 | 42.0 | 4.30e-01 | 86.6% | 92.1% |
| 4yyfA00 | 3.20.20.300 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycoside hydrolase, family 3, N-terminal domain | 0.54 | 46.0 | 3.01e-01 | 100.0% | 76.7% |
| 1kblA04 | 3.20.20.60 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains | 0.53 | 44.0 | 2.90e-01 | 100.0% | 37.7% |
| 3gzsA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 44.0 | 2.69e-01 | 100.0% | 22.8% |
| 2r0bA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.52 | 42.0 | 3.46e-01 | 100.0% | 96.0% |
| 3m1tA00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.52 | 42.0 | 2.89e-01 | 94.0% | 58.0% |
| 4e69A00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.51 | 44.0 | 2.91e-01 | 100.0% | 68.7% |
| 3dboB00 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.51 | 39.0 | 3.27e-01 | 98.5% | 45.2% |
| 2ew2A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 43.0 | 3.56e-01 | 100.0% | 93.3% |
| 1z1vA00 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.51 | 44.0 | 4.42e-01 | 98.5% | 94.3% |
| 3hwrA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 42.0 | 3.54e-01 | 98.5% | 92.2% |
| 1kw4A00 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.51 | 42.0 | 4.17e-01 | 92.5% | 87.1% |
| 3tacB03 | 1.10.150.50 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 | 0.50 | 42.0 | 4.00e-01 | 100.0% | 85.9% |
| 3kp9A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.50 | 42.0 | 3.21e-01 | 94.0% | 51.2% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3986875 | 4254.1.1.1 ↗ | alpha arrays › YoaC-like › YoaC-like › YoaC-like › DUF1889 | 0.69 | 59.0 | 5.79e-01 | 95.5% | 89.0% |
| 314012 | 4254.1.1.1 ↗ | alpha arrays › YoaC-like › YoaC-like › YoaC-like › DUF1889 | 0.66 | 57.0 | 4.92e-01 | 98.5% | 65.7% |
| 4486212 | 7014.1.1.1 ↗ | alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA | 0.65 | 50.0 | 4.38e-01 | 85.1% | 91.4% |
| 4530493 | 3455.1.1.0 ↗ | alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors | 0.64 | 48.0 | 4.79e-01 | 91.0% | 80.0% |
| 4167084 | 323.1.1.7 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase | 0.62 | 47.0 | 3.03e-01 | 80.6% | 47.8% |
| 4662973 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.61 | 40.0 | 4.00e-01 | 97.0% | 64.3% |
| 3721780 | 608.1.1.0 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like | 0.60 | 51.0 | 4.69e-01 | 97.0% | 90.0% |
| 3740077 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 53.0 | 3.86e-01 | 100.0% | 36.8% |
| 3289370 | 101.1.1.300 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_30 | 0.60 | 41.0 | 3.64e-01 | 71.6% | 74.0% |
| 5042947 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.60 | 42.0 | 4.74e-01 | 83.6% | 100.0% |
| 3798329 | 3919.1.1.0 ↗ | alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 | 0.60 | 51.0 | 4.45e-01 | 100.0% | 100.0% |
| 3283604 | 101.1.3.4 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 | 0.60 | 41.0 | 3.63e-01 | 71.6% | 74.0% |
| 3626320 | 3919.1.1.2 ↗ | alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMM_HN | 0.59 | 50.0 | 4.38e-01 | 100.0% | 100.0% |
| 3291575 | 101.1.3.4 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 | 0.59 | 39.0 | 3.54e-01 | 70.1% | 70.0% |
| 5059586 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.59 | 48.0 | 4.59e-01 | 91.0% | 87.3% |
| 3550609 | 3919.1.1.2 ↗ | alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMM_HN | 0.59 | 48.0 | 4.13e-01 | 94.0% | 91.3% |
| 4559208 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.58 | 44.0 | 3.26e-01 | 89.6% | 30.7% |
| 4394277 | 563.1.1.1 ↗ | alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP | 0.57 | 43.0 | 3.21e-01 | 91.0% | 31.4% |
| 4987595 | 2004.1.1.208 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_33 | 0.57 | 48.0 | 3.65e-01 | 100.0% | 72.5% |
| 3955106 | 101.1.3.4 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 | 0.57 | 39.0 | 3.59e-01 | 73.1% | 63.3% |
| 3299470 | 1117.1.1.1 ↗ | alpha arrays › Enhancer of polycomb-like protein 1 (Epl1) N-terminal domain › Enhancer of polycomb-like protein 1 (Epl1) N-terminal domain › Enhancer of polycomb-like protein 1 (Epl1) N-terminal domain › EPL1 | 0.55 | 48.0 | 3.56e-01 | 98.5% | 53.9% |
| 3291647 | 101.1.3.4 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 | 0.55 | 38.0 | 3.44e-01 | 71.6% | 76.8% |
| 4963273 | 622.1.1.37 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › PF25926 | 0.55 | 42.0 | 3.61e-01 | 85.1% | 82.6% |
| 3282047 | 101.1.3.4 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 | 0.55 | 38.0 | 3.40e-01 | 73.1% | 61.0% |
| 3603382 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.55 | 39.0 | 2.93e-01 | 77.6% | 51.9% |
| 5038092 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 44.0 | 4.10e-01 | 92.5% | 95.3% |
| 4969568 | 316.1.1.18 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › AbiEii | 0.53 | 43.0 | 2.93e-01 | 98.5% | 33.2% |
| 4940746 | 3457.1.1.1 ↗ | alpha bundles › GxGD membrane protease › GxGD membrane protease › GxGD membrane protease › Peptidase_A24 | 0.51 | 37.0 | 2.82e-01 | 80.6% | 90.6% |
| 3743538 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.51 | 43.0 | 3.90e-01 | 97.0% | 86.0% |