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E7
Euk-VirMacaca_fascicularis_papillomavirus_2
E7__YP_004646332__Macaca_fascicularis_papillomavirus_2__915424
Identity
- Accession:
- YP_004646332 ↗
- Protein ID:
- E7
- Kingdom:
- euk
Quality
84.1
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Betapapillomavirus›
Macaca_fascicularis_papillomavirus_2
TaxID: 915424
Cluster
View cluster (135 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 42-104
Domain cluster:
rep: transforming_protein_E7__NP_041326__Human_papillomavirus_type_16__333760__D50-96
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00527.24 best | E7 | 43.9 | 3.10e-11 | 73.0% | 47.8% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bqgA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.68 | 48.0 | 3.77e-01 | 76.2% | 58.7% |
| 3msyA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.66 | 46.0 | 3.83e-01 | 73.0% | 80.2% |
| 2gdqA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.59 | 42.0 | 3.60e-01 | 81.0% | 44.9% |
| 6muwN00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.58 | 40.0 | 2.78e-01 | 73.0% | 50.4% |
| 2bpsA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.56 | 37.0 | 3.46e-01 | 81.0% | 53.1% |
| 2v1yA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.56 | 39.0 | 3.52e-01 | 85.7% | 52.8% |
| 4ikbA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.56 | 42.0 | 3.42e-01 | 82.5% | 90.7% |
| 6tdxG01 | 3.40.1380.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit | 0.55 | 44.0 | 3.05e-01 | 87.3% | 96.7% |
| 8adnN01 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.53 | 36.0 | 2.67e-01 | 73.0% | 45.0% |
| 6cc0A01 | 3.30.450.80 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain | 0.52 | 37.0 | 2.86e-01 | 77.8% | 45.1% |
| 2wyqA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.52 | 34.0 | 3.20e-01 | 85.7% | 54.5% |
| 2dhoA00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.52 | 40.0 | 2.81e-01 | 85.7% | 61.9% |
| 1stzA03 | 3.30.390.60 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Heat-inducible transcription repressor hrca homolog; domain 3 | 0.51 | 38.0 | 3.50e-01 | 90.5% | 59.6% |
| 5jtwA06 | 6.20.50.160 | Special › Other non-globular › N-terminal domain of TfIIb › | 0.51 | 30.0 | 3.03e-01 | 79.4% | 53.2% |
| 4esbA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 40.0 | 3.42e-01 | 87.3% | 92.2% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8138 | 4123.1.1.1 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 | 0.92 | 67.0 | 7.34e-01 | 77.8% | 92.3% |
| 3686997 | 304.9.1.6 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Smg4_UPF3 | 0.60 | 43.0 | 4.21e-01 | 81.0% | 68.6% |
| 5052968 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.59 | 47.0 | 2.91e-01 | 85.7% | 69.3% |
| 3591691 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.57 | 39.0 | 3.48e-01 | 71.4% | 100.0% |
| 3453248 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.57 | 38.0 | 4.02e-01 | 90.5% | 78.2% |
| 3653569 | 221.1.1.2 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin | 0.57 | 35.0 | 3.69e-01 | 79.4% | 70.9% |
| 3442112 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.56 | 35.0 | 3.69e-01 | 79.4% | 70.9% |
| 1834407 | 3218.1.1.1 ↗ | a+b duplicates or obligate multimers › small terminase oligomerization domain › small terminase oligomerization domain › small terminase oligomerization domain › Terminase_2 | 0.56 | 33.0 | 3.06e-01 | 77.8% | 47.4% |
| 3535009 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 48.0 | 3.07e-01 | 96.8% | 62.2% |
| 3479321 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.55 | 43.0 | 2.68e-01 | 85.7% | 88.1% |
| 3218266 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.54 | 42.0 | 2.68e-01 | 87.3% | 84.8% |
| 3700547 | 109.4.1.22 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N | 0.53 | 43.0 | 2.47e-01 | 88.9% | 20.5% |
| 3517620 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.53 | 42.0 | 2.76e-01 | 90.5% | 61.9% |
| 5027341 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.53 | 40.0 | 3.01e-01 | 81.0% | 69.4% |
| 3798928 | 59.1.4.2 ↗ | beta complex topology › triple barrel › triple barrel › TFIID subunits TAF1-TAF7 › DUF3591 | 0.52 | 40.0 | 2.45e-01 | 85.7% | 26.7% |
| 3500824 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.52 | 43.0 | 2.75e-01 | 95.2% | 71.7% |
| 3470076 | 861.1.1.0 ↗ | a+b two layers › Mago nashi protein › Mago nashi protein › Mago nashi protein | 0.52 | 41.0 | 3.20e-01 | 87.3% | 57.1% |
| 3577144 | 3957.1.1.0 ↗ | a+b two layers › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 | 0.52 | 35.0 | 3.78e-01 | 73.0% | 90.0% |
| 3224634 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.51 | 37.0 | 2.42e-01 | 82.5% | 78.1% |
| 3423947 | 7512.1.1.6 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 | 0.51 | 39.0 | 2.69e-01 | 88.9% | 90.6% |
| 2556077 | 7519.1.1.1 ↗ | a/b three-layered sandwiches › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP-synt | 0.51 | 39.0 | 2.57e-01 | 87.3% | 40.3% |
| 3753029 | 221.15.1.0 ↗ | a+b two layers › beta-Grasp › beta-grasp fold domain in leucine-tRNA ligase › beta-grasp fold domain in leucine-tRNA ligase | 0.50 | 32.0 | 3.53e-01 | 84.1% | 100.0% |
| 3931288 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.50 | 40.0 | 2.80e-01 | 90.5% | 89.2% |
| 4949578 | 3957.1.1.0 ↗ | a+b two layers › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 › EKC/KEOPS complex subunit GON7 | 0.50 | 35.0 | 3.65e-01 | 77.8% | 80.0% |