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E7

Euk-Vir

Eidolon_helvum_papillomavirus_2

E7__YP_009345078__Eidolon_helvum_papillomavirus_2__1335476

Identity

Accession:
YP_009345078 ↗
Protein ID:
E7
Kingdom:
euk

Quality

62.2 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Psipapillomavirus› Eidolon_helvum_papillomavirus_2

TaxID: 1335476

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 32-42_116-166
PDB
Domain cluster: rep: transforming_protein_E7__NP_041326__Human_papillomavirus_type_16__333760__D50-96
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00527.24 best E7 40.3 3.90e-10 90.3% 52.2%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ewlA00 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.89 71.0 7.42e-01 85.5% 92.9%
1x67A01 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.66 48.0 3.81e-01 79.0% 81.2%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.64 49.0 3.99e-01 85.5% 62.4%
4p2iA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.61 47.0 3.95e-01 87.1% 96.6%
2hqlA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 44.0 3.96e-01 80.6% 61.5%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.60 46.0 4.69e-01 83.9% 93.3%
3ulbA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 42.0 3.90e-01 79.0% 59.0%
2crfA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 39.0 3.23e-01 71.0% 52.8%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.57 44.0 4.17e-01 87.1% 84.8%
2ar5A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.57 45.0 3.72e-01 87.1% 93.2%
4i0kA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 43.0 3.77e-01 82.3% 78.9%
3oyyA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.57 41.0 4.10e-01 79.0% 83.3%
1v1qA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 44.0 3.75e-01 87.1% 62.7%
8b4hA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.56 44.0 3.38e-01 91.9% 99.4%
1uebA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.56 41.0 4.09e-01 79.0% 87.3%
1iz6A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.55 43.0 4.18e-01 83.9% 81.2%
3ebwA01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.55 39.0 3.12e-01 79.0% 66.9%
3ecrB03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.54 41.0 3.65e-01 88.7% 72.5%
3cpfA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.54 42.0 4.16e-01 83.9% 81.5%
4by6B00 2.30.30.1020 Mainly Beta › Roll › SH3 type barrels. › CCR4-NOT complex subunit 2/3/5, C-terminal domain 0.54 36.0 2.78e-01 71.0% 50.0%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 44.0 4.22e-01 95.2% 90.5%
7r97A02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 40.0 3.95e-01 88.7% 75.0%
4q9cA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 39.0 3.44e-01 83.9% 82.9%
1y7uA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.53 42.0 3.26e-01 95.2% 89.6%
2giaB00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.53 43.0 3.40e-01 96.8% 72.6%
4c0fC00 2.30.30.1020 Mainly Beta › Roll › SH3 type barrels. › CCR4-NOT complex subunit 2/3/5, C-terminal domain 0.52 38.0 3.23e-01 80.6% 60.7%
2nlkA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.52 39.0 2.64e-01 82.3% 57.3%
2o0aA00 3.40.850.20 Alpha Beta › 3-Layer(aba) Sandwich › Kinesin › 0.52 39.0 2.60e-01 82.3% 93.7%
3io5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 38.0 2.59e-01 83.9% 19.6%
4c0dB00 2.30.30.1020 Mainly Beta › Roll › SH3 type barrels. › CCR4-NOT complex subunit 2/3/5, C-terminal domain 0.52 35.0 2.62e-01 72.6% 46.1%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.51 41.0 3.62e-01 91.9% 100.0%
1q48A00 3.90.1010.10 Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › 0.51 39.0 3.16e-01 87.1% 49.3%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.51 39.0 2.71e-01 87.1% 38.9%
5mu3B00 3.40.50.12050 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 43.0 3.28e-01 100.0% 62.6%
3u2sC00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.50 38.0 3.42e-01 83.9% 75.6%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
8138 4123.1.1.1 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.94 74.0 8.07e-01 82.3% 98.1%
None — 0.72 50.0 3.07e-01 74.2% 27.3%
2971782 2484.1.1.39 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Fumble 0.71 52.0 4.30e-01 80.6% 43.0%
3940677 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.71 49.0 3.47e-01 72.6% 29.7%
3608102 330.1.1.0 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.67 49.0 4.79e-01 80.6% 85.7%
5072662 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.66 51.0 3.99e-01 83.9% 96.3%
3723171 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.66 48.0 3.61e-01 77.4% 34.0%
4316603 4263.2.1.0 ↗ a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain 0.65 46.0 4.39e-01 75.8% 68.0%
4139587 896.1.1.0 ↗ a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.64 46.0 4.18e-01 77.4% 68.2%
3587376 386.1.1.344 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › Arm-DNA-bind_4 0.64 45.0 4.76e-01 75.8% 98.2%
4932637 330.2.1.0 ↗ a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) 0.63 48.0 4.33e-01 85.5% 76.7%
3284948 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.63 52.0 4.79e-01 95.2% 84.7%
5023443 330.4.1.0 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.63 48.0 4.80e-01 85.5% 89.2%
3264336 277.1.1.0 ↗ a+b two layers › PX domain › PX domain › PX domain 0.63 45.0 4.07e-01 79.0% 92.2%
3740379 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.62 43.0 4.43e-01 74.2% 80.0%
3588192 4325.1.1.7 ↗ mixed a+b and a/b › YegP-like › YegP-like › YegP-like › Arm-DNA-bind_4 0.62 42.0 4.56e-01 72.6% 100.0%
4947833 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.62 44.0 3.59e-01 77.4% 53.6%
4965501 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.62 47.0 4.24e-01 85.5% 70.0%
4024738 220.1.1.243 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PF30062 0.61 45.0 3.83e-01 79.0% 51.4%
3660107 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.61 47.0 3.74e-01 87.1% 87.1%
4135153 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.60 49.0 4.68e-01 93.5% 88.0%
3472467 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.60 45.0 4.24e-01 80.6% 82.7%
3483729 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.60 46.0 3.79e-01 85.5% 93.3%
4937952 206.1.3.3 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › PPDK_N 0.59 44.0 2.92e-01 79.0% 85.4%
3935357 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 41.0 3.45e-01 75.8% 43.3%
3251342 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.59 44.0 3.63e-01 82.3% 86.7%
3249076 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 44.0 3.39e-01 82.3% 86.9%
4029815 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 41.0 3.37e-01 77.4% 39.2%
5009939 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 42.0 3.65e-01 79.0% 48.6%
3927710 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.59 42.0 3.20e-01 79.0% 69.1%
4048220 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.58 46.0 4.27e-01 88.7% 75.0%
3693249 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.58 43.0 3.46e-01 80.6% 85.4%
3900401 277.1.1.0 ↗ a+b two layers › PX domain › PX domain › PX domain 0.58 44.0 3.62e-01 85.5% 87.2%
3173646 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.58 44.0 3.33e-01 85.5% 72.1%
3266842 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.58 43.0 3.59e-01 85.5% 88.8%
3236475 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.57 43.0 3.44e-01 83.9% 86.7%
4967370 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.57 43.0 3.90e-01 85.5% 65.6%
3948387 1104.1.1.1 ↗ a+b complex topology › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › Helicase Cch N-terminal domain › DUF927 0.57 47.0 3.65e-01 96.8% 92.7%
5036880 330.1.1.35 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › LeuA_dimer 0.56 46.0 4.46e-01 91.9% 84.3%
3784232 277.1.1.0 ↗ a+b two layers › PX domain › PX domain › PX domain 0.56 44.0 3.50e-01 90.3% 77.2%
3785325 376.1.1.21 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 0.56 48.0 4.29e-01 98.4% 81.1%
3608162 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.56 40.0 3.10e-01 80.6% 72.7%
4054729 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.55 42.0 4.06e-01 87.1% 85.3%
3265334 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.55 41.0 3.53e-01 83.9% 73.6%
5068126 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 46.0 3.89e-01 95.2% 81.8%
3598064 277.1.1.0 ↗ a+b two layers › PX domain › PX domain › PX domain 0.54 44.0 3.60e-01 95.2% 87.2%
3389979 319.1.1.1 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.53 39.0 3.25e-01 82.3% 50.0%
3414096 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.53 44.0 3.58e-01 96.8% 91.5%
3275610 304.112.1.1 ↗ a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain › ArgoL1 0.53 37.0 2.80e-01 75.8% 83.0%
3782183 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.53 40.0 2.41e-01 83.9% 45.4%
4524129 330.4.1.1 ↗ a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.52 43.0 3.81e-01 95.2% 87.4%
1108449 4.1.1.41 ↗ beta barrels › SH3 › SH3 › SH3 › NOT2_3_5_C 0.52 35.0 2.62e-01 72.6% 46.1%
5078623 868.1.1.1 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.51 36.0 3.00e-01 79.0% 48.5%
3223243 6165.1.1.1 ↗ beta sandwiches › Piezo CTL2 domain › Piezo CTL2 domain › Piezo CTL2 domain › Piezo_RRas_bdg 0.51 41.0 2.79e-01 96.8% 65.5%
3590584 264.2.1.0 ↗ beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain 0.50 37.0 3.07e-01 85.5% 85.2%
4141218 4099.1.1.6 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Ctf19_RWD2 0.50 38.0 3.58e-01 83.9% 76.2%