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E7

Euk-Vir

Leptonychotes_weddellii_papillomavirus_2

E7__YP_009465989__Leptonychotes_weddellii_papillomavirus_2__2077303

Identity

Accession:
YP_009465989 ↗
Protein ID:
E7
Kingdom:
euk

Quality

81.5 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Leptonychotes_weddellii_papillomavirus_2

TaxID: 2077303

Cluster

View cluster (135 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 43-90
PDB
Domain cluster: rep: transforming_protein_E7__NP_041326__Human_papillomavirus_type_16__333760__D50-96
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00527.24 best E7 48.3 1.20e-12 91.7% 47.8%
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.97 70.0 7.69e-01 75.0% 92.3%
2ewlA00 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.94 86.0 8.18e-01 100.0% 85.7%
1j5yA02 3.30.1340.20 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › 3H domain 0.71 52.0 4.08e-01 79.2% 93.5%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.71 52.0 3.58e-01 79.2% 40.7%
2jl8102 3.30.160.850 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 47.0 4.80e-01 85.4% 77.8%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.66 43.0 4.13e-01 75.0% 56.4%
1pc6A00 1.10.3790.10 Mainly Alpha › Orthogonal Bundle › NinB fold › NinB 0.65 47.0 3.36e-01 77.1% 57.4%
1fx2A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.64 46.0 3.02e-01 79.2% 32.3%
2vd3A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 46.0 4.11e-01 81.2% 81.1%
7ejoB01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.63 44.0 3.76e-01 77.1% 43.4%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.62 45.0 3.71e-01 79.2% 43.5%
2xauA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 42.0 2.89e-01 75.0% 76.0%
5yvxA00 3.30.40.100 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.60 48.0 4.47e-01 89.6% 71.7%
7ocxC01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 41.0 3.68e-01 77.1% 94.7%
2kgfA00 1.10.375.10 Mainly Alpha › Orthogonal Bundle › Human Immunodeficiency Virus Type 1 Capsid Protein › Human Immunodeficiency Virus Type 1 Capsid Protein 0.59 42.0 3.03e-01 77.1% 85.7%
4lmyA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.58 47.0 4.62e-01 97.9% 98.1%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.58 42.0 3.49e-01 79.2% 44.7%
3p2aA01 2.30.30.380 Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 0.58 38.0 4.29e-01 91.7% 91.7%
1vigA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.58 40.0 3.71e-01 77.1% 94.4%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.58 48.0 4.53e-01 100.0% 88.3%
5eyaF00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.58 36.0 3.11e-01 91.7% 40.8%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.57 41.0 3.59e-01 83.3% 49.4%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.56 47.0 2.70e-01 95.8% 59.1%
3eytB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.56 40.0 2.83e-01 77.1% 23.4%
6eudA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 39.0 2.77e-01 77.1% 74.7%
1yguA02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.55 39.0 2.49e-01 77.1% 89.1%
7r0kA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.55 40.0 2.82e-01 79.2% 34.3%
4hjwA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.54 40.0 2.40e-01 81.2% 15.5%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.54 40.0 3.40e-01 89.6% 94.7%
4l8nA03 3.30.160.670 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 42.0 3.05e-01 95.8% 32.9%
2fe3A02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.53 43.0 4.18e-01 97.9% 94.7%
6zwwC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 39.0 2.77e-01 83.3% 74.0%
1ln0A00 3.40.1440.10 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease 0.53 43.0 3.62e-01 95.8% 96.7%
5sviB00 3.30.40.100 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.53 39.0 3.89e-01 89.6% 77.4%
2pe4A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 45.0 2.69e-01 100.0% 82.0%
6uqjA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 36.0 2.24e-01 75.0% 18.6%
1v6eA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 38.0 3.35e-01 83.3% 100.0%
2xigA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.52 41.0 4.05e-01 97.9% 96.4%
1wmhA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 37.0 3.16e-01 77.1% 92.8%
5ffiE00 3.10.20.30 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain 0.52 36.0 2.95e-01 81.2% 35.3%
2dafA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 42.0 3.71e-01 93.8% 98.7%
2z86D02 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.51 41.0 2.70e-01 97.9% 84.6%
3i3lA02 3.30.390.160 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.51 40.0 3.04e-01 91.7% 85.6%
ECOD (40)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
8138 4123.1.1.1 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.95 89.0 8.64e-01 100.0% 92.3%
8137 4123.1.1.1 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.94 86.0 8.43e-01 100.0% 92.3%
3337279 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.79 54.0 6.05e-01 97.9% 100.0%
4928795 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.69 48.0 4.95e-01 93.8% 77.8%
3649366 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.65 43.0 3.61e-01 75.0% 38.8%
3238459 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.63 42.0 3.92e-01 79.2% 52.3%
3498497 301.7.1.0 ↗ a+b three layers › Bacillus chorismate mutase-like › YjgF-like › YjgF-like 0.62 44.0 2.85e-01 75.0% 34.2%
3512976 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.62 42.0 2.60e-01 70.8% 48.1%
4294893 375.1.1.240 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Zn_ribbon_Brz 0.62 52.0 4.82e-01 93.8% 88.3%
4991835 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.61 49.0 4.90e-01 95.8% 88.0%
4016025 2485.1.1.39 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › GST_N_2 0.60 39.0 2.96e-01 75.0% 24.8%
3308207 5.1.3.22 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › GSDH 0.60 42.0 2.66e-01 75.0% 88.1%
5010744 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.60 49.0 4.58e-01 100.0% 80.0%
2793102 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.60 39.0 4.32e-01 93.8% 94.1%
3360654 376.1.3.57 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf_ULT1 0.59 46.0 4.55e-01 95.8% 92.7%
4061421 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.58 39.0 3.39e-01 83.3% 43.8%
5050610 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.58 44.0 3.97e-01 87.5% 68.6%
3258276 4081.1.1.2 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › VIT 0.57 40.0 2.63e-01 81.2% 15.6%
3233262 706.1.1.0 ↗ beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE 0.57 37.0 4.07e-01 77.1% 88.6%
3369564 130.1.1.39 ↗ alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › DUF7086 0.57 49.0 3.60e-01 100.0% 42.9%
3737908 221.1.1.94 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › AIP3 0.57 40.0 3.43e-01 93.8% 45.0%
3285877 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 37.0 2.43e-01 83.3% 14.7%
4422146 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.56 40.0 2.71e-01 77.1% 72.2%
4507143 219.1.1.111 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core, Rad4 0.56 44.0 2.73e-01 87.5% 85.7%
3988478 857.1.1.1 ↗ a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.55 46.0 3.77e-01 100.0% 50.0%
3203770 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 37.0 3.60e-01 83.3% 63.6%
3596419 375.1.1.77 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DUF4379 0.54 40.0 4.25e-01 95.8% 97.5%
4472395 7512.1.1.6 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 0.54 44.0 2.79e-01 95.8% 88.7%
4890114 109.4.1.3608 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_10, TPR_16, TPR_19, ARM_TT21_4th 0.53 36.0 1.99e-01 70.8% 4.7%
4026560 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.53 37.0 2.85e-01 72.9% 92.0%
3918540 386.1.1.281 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF27082 0.52 35.0 3.69e-01 91.7% 87.5%
4929347 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.52 39.0 3.90e-01 93.8% 81.8%
3933447 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.52 36.0 2.96e-01 85.4% 36.2%
3610148 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.52 37.0 2.62e-01 79.2% 82.2%
4930302 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.52 35.0 3.88e-01 72.9% 97.1%
3798928 59.1.4.2 ↗ beta complex topology › triple barrel › triple barrel › TFIID subunits TAF1-TAF7 › DUF3591 0.52 35.0 2.03e-01 70.8% 26.7%
3464487 221.1.1.2 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.51 43.0 3.80e-01 100.0% 100.0%
3839446 2002.1.1.52 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Peptidase_U32 0.50 42.0 2.63e-01 100.0% 92.0%
4929843 4123.1.1.0 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like 0.50 39.0 3.90e-01 91.7% 88.0%
4944397 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.50 34.0 3.39e-01 83.3% 66.0%