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E7
Euk-VirMacaca_mulatta_papillomavirus_4
E7__YP_009551987__Macaca_mulatta_papillomavirus_4__2294152
Identity
- Accession:
- YP_009551987 ↗
- Protein ID:
- E7
- Kingdom:
- euk
Quality
80.4
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Macaca_mulatta_papillomavirus_4
TaxID: 2294152
Cluster
View cluster (135 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 41-88
Domain cluster:
rep: transforming_protein_E7__NP_041326__Human_papillomavirus_type_16__333760__D50-96
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00527.24 best | E7 | 43.7 | 3.40e-11 | 91.7% | 46.7% |
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b9dA01 | 3.30.160.330 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.94 | 67.0 | 7.40e-01 | 75.0% | 92.3% |
| 2ewlA00 | 3.30.160.330 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.94 | 86.0 | 8.16e-01 | 100.0% | 85.7% |
| 5yppA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.75 | 56.0 | 4.56e-01 | 81.2% | 75.6% |
| 1j5yA02 | 3.30.1340.20 | Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › 3H domain | 0.72 | 53.0 | 4.14e-01 | 79.2% | 93.5% |
| 4kyzA00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.71 | 52.0 | 3.59e-01 | 79.2% | 40.7% |
| 1fx2A00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.66 | 48.0 | 3.09e-01 | 79.2% | 32.3% |
| 7ejoB01 | 3.30.2260.10 | Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary | 0.66 | 46.0 | 3.88e-01 | 77.1% | 43.4% |
| 2vd3A03 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 45.0 | 4.06e-01 | 81.2% | 81.1% |
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.62 | 44.0 | 3.68e-01 | 79.2% | 41.3% |
| 2jvfA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.60 | 43.0 | 3.58e-01 | 79.2% | 44.7% |
| 7ocxC01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.60 | 42.0 | 3.73e-01 | 77.1% | 94.7% |
| 1nh8A03 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 43.0 | 3.97e-01 | 81.2% | 88.1% |
| 4llgM00 | 3.10.20.510 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › RNA polymerase inhibitor | 0.60 | 44.0 | 4.39e-01 | 83.3% | 78.0% |
| 2jxtA01 | 3.10.20.10 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.59 | 43.0 | 3.80e-01 | 81.2% | 55.3% |
| 4lmyA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.58 | 47.0 | 4.63e-01 | 97.9% | 98.1% |
| 1neiA00 | 3.30.160.220 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG | 0.58 | 49.0 | 4.64e-01 | 100.0% | 88.3% |
| 4efoA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.58 | 44.0 | 3.61e-01 | 83.3% | 85.4% |
| 1l1lA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.57 | 48.0 | 2.76e-01 | 95.8% | 59.1% |
| 6eudA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 41.0 | 2.84e-01 | 77.1% | 74.7% |
| 6zwwC01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 41.0 | 2.88e-01 | 81.2% | 74.0% |
| 4cbgD02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 40.0 | 2.77e-01 | 75.0% | 73.9% |
| 3p2aA01 | 2.30.30.380 | Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 | 0.55 | 38.0 | 4.25e-01 | 97.9% | 100.0% |
| 2gffA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 38.0 | 3.22e-01 | 79.2% | 77.1% |
| 4mtdA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.54 | 44.0 | 4.15e-01 | 97.9% | 85.7% |
| 1rzmA01 | 3.30.70.1140 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Phospho-2-dehydro-3-deoxyheptonate aldolase; domain 1 | 0.54 | 38.0 | 3.36e-01 | 79.2% | 73.8% |
| 4mtnA01 | 3.30.1480.10 | Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain | 0.54 | 42.0 | 3.56e-01 | 95.8% | 100.0% |
| 2kd0A01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.54 | 39.0 | 3.48e-01 | 79.2% | 53.5% |
| 1wmhA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 38.0 | 3.22e-01 | 77.1% | 92.8% |
| 5ffiE00 | 3.10.20.30 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain | 0.53 | 37.0 | 2.99e-01 | 81.2% | 35.3% |
| 5sviB00 | 3.30.40.100 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.53 | 41.0 | 4.06e-01 | 91.7% | 79.2% |
| 4djhA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 37.0 | 2.40e-01 | 79.2% | 38.0% |
| 6uqjA02 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.53 | 36.0 | 2.26e-01 | 75.0% | 18.6% |
| 1yguA02 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.53 | 37.0 | 2.40e-01 | 77.1% | 57.6% |
| 2xigA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.52 | 41.0 | 4.05e-01 | 97.9% | 96.4% |
| 2pe4A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.52 | 45.0 | 2.67e-01 | 100.0% | 82.0% |
| 2fe3A02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.52 | 42.0 | 4.03e-01 | 97.9% | 94.7% |
| 3t7aA02 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.52 | 37.0 | 2.51e-01 | 79.2% | 37.6% |
| 5r0dB01 | 2.60.34.20 | Mainly Beta › Sandwich › Substrate Binding Domain Of DNAk; Chain A, domain 1 › | 0.51 | 37.0 | 2.71e-01 | 77.1% | 69.9% |
| 7bi2A01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.51 | 37.0 | 2.98e-01 | 81.2% | 73.8% |
| 1v6eA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.51 | 37.0 | 3.28e-01 | 83.3% | 100.0% |
| 1ln0A00 | 3.40.1440.10 | Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease | 0.50 | 39.0 | 3.37e-01 | 95.8% | 97.8% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8137 | 4123.1.1.1 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 | 0.94 | 86.0 | 8.40e-01 | 100.0% | 92.3% |
| 8138 | 4123.1.1.1 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 | 0.92 | 85.0 | 8.29e-01 | 100.0% | 92.3% |
| 4029830 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.70 | 48.0 | 3.37e-01 | 72.9% | 23.9% |
| 4928795 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.69 | 49.0 | 5.03e-01 | 95.8% | 80.0% |
| 3935205 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.69 | 52.0 | 3.93e-01 | 81.2% | 32.5% |
| 3649366 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.64 | 42.0 | 3.55e-01 | 75.0% | 38.8% |
| 4991835 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.62 | 50.0 | 4.98e-01 | 93.8% | 88.0% |
| 5010744 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.60 | 50.0 | 4.64e-01 | 100.0% | 80.0% |
| 3983569 | 101.1.2.25 ↗ | alpha arrays › HTH › HTH › winged helix domain › FUR | 0.60 | 44.0 | 3.09e-01 | 79.2% | 70.6% |
| 3258276 | 4081.1.1.2 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › VIT | 0.60 | 41.0 | 2.71e-01 | 81.2% | 15.6% |
| 3308207 | 5.1.3.22 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › GSDH | 0.60 | 41.0 | 2.63e-01 | 75.0% | 88.1% |
| 3360654 | 376.1.3.57 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf_ULT1 | 0.59 | 47.0 | 4.58e-01 | 95.8% | 92.7% |
| 4422146 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.58 | 41.0 | 2.77e-01 | 77.1% | 72.2% |
| 4061421 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.58 | 40.0 | 3.41e-01 | 83.3% | 43.8% |
| 4126322 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.55 | 39.0 | 3.57e-01 | 75.0% | 86.2% |
| 4016025 | 2485.1.1.39 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › GST_N_2 | 0.55 | 37.0 | 2.83e-01 | 75.0% | 26.4% |
| 3285877 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 37.0 | 2.49e-01 | 72.9% | 21.8% |
| 3242889 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.55 | 38.0 | 3.28e-01 | 83.3% | 42.4% |
| 5063119 | 2008.1.1.59 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 | 0.55 | 44.0 | 2.83e-01 | 89.6% | 37.8% |
| 3889364 | 221.1.1.164 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PF29299 | 0.54 | 40.0 | 3.45e-01 | 83.3% | 98.8% |
| 4929347 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.53 | 41.0 | 4.00e-01 | 93.8% | 81.8% |
| 4930302 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.53 | 36.0 | 4.01e-01 | 72.9% | 97.1% |
| 3918540 | 386.1.1.281 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF27082 | 0.52 | 35.0 | 3.72e-01 | 91.7% | 87.5% |
| 3588171 | 101.1.2.25 ↗ | alpha arrays › HTH › HTH › winged helix domain › FUR | 0.52 | 41.0 | 3.07e-01 | 95.8% | 37.2% |
| 4944397 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.52 | 35.0 | 3.49e-01 | 83.3% | 66.0% |
| 3464487 | 221.1.1.2 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin | 0.51 | 43.0 | 3.81e-01 | 100.0% | 100.0% |
| 4987387 | 219.1.1.76 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF553 | 0.51 | 35.0 | 2.50e-01 | 79.2% | 87.9% |
| 4929843 | 4123.1.1.0 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like | 0.50 | 39.0 | 3.88e-01 | 91.7% | 88.0% |