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E7

Euk-Vir

Canine_papillomavirus_21

E7__YP_009552034__Canine_papillomavirus_21__2304619

Identity

Accession:
YP_009552034 ↗
Protein ID:
E7
Kingdom:
euk

Quality

77.5 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Taupapillomavirus› Canine_papillomavirus_21

TaxID: 2304619

Cluster

View cluster (135 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 41-87
PDB
Domain cluster: rep: transforming_protein_E7__NP_041326__Human_papillomavirus_type_16__333760__D50-96
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ewlA00 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.93 84.0 7.91e-01 100.0% 82.1%
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.92 65.0 7.05e-01 76.6% 89.7%
1j5yA02 3.30.1340.20 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › 3H domain 0.78 58.0 4.43e-01 80.9% 91.6%
4lvnP00 3.30.70.2380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.76 57.0 4.72e-01 80.9% 85.2%
1ltlA03 2.20.28.10 Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › 0.72 49.0 4.83e-01 95.7% 67.3%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.67 49.0 3.41e-01 80.9% 38.3%
7ejoB01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.66 46.0 3.85e-01 78.7% 42.2%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.63 41.0 3.99e-01 76.6% 56.4%
2i9dA00 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.63 46.0 3.07e-01 83.0% 87.3%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.61 45.0 3.91e-01 83.0% 53.9%
4jn7A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.60 48.0 3.77e-01 97.9% 69.7%
4me3A03 2.20.28.10 Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › 0.60 45.0 4.33e-01 100.0% 70.9%
4lmyA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.60 50.0 4.85e-01 100.0% 96.3%
1pjqA02 3.30.160.110 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Sirohaem synthase, central domain 0.59 41.0 4.39e-01 83.0% 97.2%
3p2aA01 2.30.30.380 Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 0.59 39.0 4.31e-01 97.9% 88.9%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.59 42.0 3.46e-01 80.9% 39.4%
2qsdA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 44.0 3.99e-01 85.1% 58.2%
4pofA03 2.20.28.10 Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › 0.59 40.0 3.95e-01 95.7% 68.0%
3weeA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.58 41.0 2.78e-01 72.3% 63.9%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.58 42.0 3.49e-01 80.9% 41.3%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.56 39.0 3.65e-01 83.0% 56.9%
2fe3A02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.55 44.0 4.29e-01 100.0% 96.5%
4efoA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.55 41.0 3.42e-01 85.1% 84.3%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.54 42.0 3.62e-01 100.0% 100.0%
2xigA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.54 44.0 4.31e-01 100.0% 96.4%
2mqjA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 39.0 3.41e-01 80.9% 92.2%
7ct1A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 41.0 3.40e-01 85.1% 98.8%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.53 45.0 2.61e-01 97.9% 22.5%
5sviB00 3.30.40.100 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.53 42.0 4.11e-01 93.6% 79.2%
2kd0A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 38.0 3.39e-01 78.7% 53.5%
7bi2A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 38.0 2.99e-01 78.7% 73.8%
6kykA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 40.0 3.37e-01 85.1% 98.8%
2lrwA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 38.0 3.31e-01 78.7% 47.4%
2c60A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 39.0 3.33e-01 80.9% 89.9%
7r0kA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.53 38.0 2.70e-01 78.7% 97.6%
7pyvC02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 38.0 3.42e-01 80.9% 98.6%
5ffiE00 3.10.20.30 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain 0.52 38.0 3.05e-01 80.9% 99.0%
1yuzA02 2.20.28.10 Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › 0.52 32.0 3.39e-01 95.7% 68.4%
2mlbA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 39.0 3.36e-01 85.1% 89.9%
6uqjA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 37.0 2.32e-01 80.9% 19.1%
1wmhA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.51 38.0 3.22e-01 80.9% 91.6%
2pvuA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.51 41.0 3.21e-01 100.0% 37.4%
3qa8G02 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.50 38.0 3.27e-01 85.1% 93.7%
4rayA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.50 40.0 3.95e-01 95.7% 96.0%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
8138 4123.1.1.1 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.93 83.0 8.06e-01 100.0% 88.5%
4951473 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.64 48.0 4.37e-01 80.9% 63.5%
4991835 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.64 51.0 5.04e-01 95.7% 84.0%
3308207 5.1.3.22 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › GSDH 0.62 43.0 2.72e-01 74.5% 87.7%
4937773 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.62 46.0 4.33e-01 80.9% 69.0%
3216210 3115.1.1.0 ↗ a+b two layers › GP2-like › RplX-like › RplX-like 0.61 43.0 4.33e-01 85.1% 74.0%
5010744 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.60 50.0 4.61e-01 100.0% 81.5%
3709956 221.1.1.2 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.58 40.0 3.49e-01 85.1% 46.6%
3737908 221.1.1.94 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › AIP3 0.58 40.0 3.37e-01 80.9% 42.5%
3399206 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.58 40.0 3.37e-01 85.1% 41.0%
5067865 3115.1.1.0 ↗ a+b two layers › GP2-like › RplX-like › RplX-like 0.58 43.0 3.84e-01 83.0% 67.1%
3360654 376.1.3.57 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf_ULT1 0.58 46.0 4.52e-01 97.9% 90.9%
5051200 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.57 43.0 3.70e-01 85.1% 98.8%
3251876 221.1.1.56 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › FERM_f0 0.57 42.0 3.55e-01 80.9% 97.5%
4846323 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.57 43.0 3.86e-01 85.1% 57.1%
5079246 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.57 43.0 3.44e-01 83.0% 94.7%
3783322 221.1.1.2 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.57 43.0 3.75e-01 85.1% 96.0%
3252553 221.1.1.2 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.55 42.0 3.66e-01 85.1% 96.0%
3900526 221.1.1.12 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RBD 0.55 41.0 3.52e-01 83.0% 87.5%
3702708 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.55 40.0 3.26e-01 85.1% 40.0%
3266011 221.1.1.44 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Rad60-SLD 0.55 41.0 3.48e-01 85.1% 88.0%
3526122 109.3.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.55 41.0 2.65e-01 85.1% 35.3%
3889364 221.1.1.164 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PF29299 0.54 41.0 3.52e-01 85.1% 97.5%
3486368 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 37.0 3.17e-01 87.2% 41.2%
3882461 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 40.0 3.52e-01 83.0% 93.3%
3704645 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 39.0 3.23e-01 80.9% 96.7%
3583377 386.1.1.1 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2 0.54 38.0 3.47e-01 78.7% 55.4%
3740159 221.1.1.24 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ATG5_UblB 0.54 37.0 3.19e-01 74.5% 43.8%
3252830 221.1.1.2 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.53 40.0 3.36e-01 85.1% 83.5%
4029085 11.16.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › N-terminal domain in A1 cistron-splicing factor AAR2 › N-terminal domain in A1 cistron-splicing factor AAR2 › AAR2_1st 0.53 41.0 3.00e-01 87.2% 60.0%
3259752 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.53 38.0 3.12e-01 78.7% 95.6%
3781912 221.1.1.2 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.53 40.0 3.59e-01 85.1% 97.1%
3895031 221.1.1.94 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › AIP3 0.52 37.0 3.10e-01 76.6% 50.6%
3679515 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.52 37.0 3.72e-01 85.1% 88.9%
4947243 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.52 42.0 3.67e-01 93.6% 96.0%
4929843 4123.1.1.0 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like 0.51 40.0 3.97e-01 95.7% 92.0%
4874840 704.1.1.1 ↗ beta complex topology › Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) › Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) › Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) › CoV_nucleocap 0.51 34.0 2.84e-01 70.2% 87.2%
3259141 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.51 35.0 3.40e-01 85.1% 61.7%
4881180 221.1.1.1 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Fer2 0.50 37.0 2.83e-01 80.9% 94.2%
3897370 3346.1.1.5 ↗ a+b two layers › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › ODR4-like 0.50 42.0 2.85e-01 100.0% 95.6%
3933447 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.50 37.0 2.95e-01 78.7% 41.9%
3533135 2492.1.1.36 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › ODR4-like 0.50 42.0 2.80e-01 100.0% 93.0%