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E7_protein

Euk-Vir

Human_papillomavirus_179

E7_protein__YP_008433327__Human_papillomavirus_179__1472342

Identity

Accession:
YP_008433327 ↗
Protein ID:
E7_protein
Kingdom:
euk

Quality

79.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 41-90
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00527.24 best E7 44.2 2.40e-11 90.0% 47.8%
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.96 68.0 7.65e-01 74.0% 94.9%
2ewlA00 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.93 83.0 8.01e-01 98.0% 87.5%
2joqA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.79 59.0 5.14e-01 80.0% 92.0%
5yppA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.74 55.0 4.54e-01 80.0% 76.7%
2jheA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.72 51.0 4.38e-01 76.0% 79.0%
3buxB03 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.71 49.0 4.12e-01 78.0% 41.9%
1vwxr00 3.30.390.110 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.70 51.0 3.82e-01 78.0% 35.2%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.70 51.0 3.54e-01 78.0% 41.3%
1khmA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.69 50.0 4.17e-01 78.0% 77.5%
1tdjA03 3.40.1020.10 Alpha Beta › 3-Layer(aba) Sandwich › Biosynthetic Threonine Deaminase; domain 3 › Biosynthetic Threonine Deaminase; Domain 3 0.67 58.0 4.05e-01 98.0% 74.5%
3m05B01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 48.0 3.99e-01 78.0% 69.6%
2gdqA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.65 53.0 4.26e-01 96.0% 71.0%
2vd3A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 46.0 4.14e-01 80.0% 82.4%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.64 47.0 4.11e-01 80.0% 65.8%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.62 44.0 4.14e-01 80.0% 60.0%
1j4wA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.62 44.0 3.98e-01 78.0% 94.6%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.61 44.0 3.69e-01 78.0% 43.5%
2v3sA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.61 44.0 3.69e-01 80.0% 41.7%
5xpcA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.61 40.0 3.45e-01 72.0% 41.2%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.60 51.0 4.86e-01 98.0% 90.0%
1qxfA00 2.20.25.100 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › Ribosomal protein S27 0.60 39.0 3.79e-01 100.0% 58.6%
2xauA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 41.0 2.82e-01 72.0% 76.0%
3h4rA00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.60 49.0 3.23e-01 94.0% 51.1%
2xc8A00 2.60.40.2980 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 41.0 3.16e-01 80.0% 30.6%
4d2kB00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 41.0 3.52e-01 76.0% 45.0%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.59 43.0 3.77e-01 80.0% 50.6%
5mu3B00 3.40.50.12050 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 42.0 2.91e-01 76.0% 39.9%
1h0hB01 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 41.0 3.02e-01 76.0% 76.7%
4dzdA02 3.30.70.1210 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 2 0.58 42.0 3.26e-01 80.0% 84.6%
2dhoA00 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.58 43.0 2.84e-01 80.0% 60.0%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.58 41.0 3.48e-01 78.0% 44.7%
1wfyA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.58 42.0 3.80e-01 80.0% 100.0%
3p2aA01 2.30.30.380 Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 0.58 37.0 4.11e-01 96.0% 91.7%
4lmyA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.58 46.0 4.57e-01 96.0% 100.0%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.57 47.0 2.72e-01 94.0% 58.9%
4ad8A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 39.0 2.45e-01 72.0% 68.7%
3h20A01 3.30.1490.240 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain 0.57 39.0 3.69e-01 80.0% 56.1%
1dgsA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.57 41.0 3.37e-01 82.0% 40.0%
8b4hA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.56 42.0 3.16e-01 92.0% 81.5%
6eudA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 38.0 2.70e-01 74.0% 74.7%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.54 41.0 3.48e-01 90.0% 100.0%
3wa1A01 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.54 42.0 2.94e-01 86.0% 35.6%
2qrdE01 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.54 36.0 2.52e-01 72.0% 40.0%
7bi2A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 36.0 2.95e-01 74.0% 75.7%
3t5tB01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.53 37.0 2.36e-01 74.0% 24.0%
4lq0A02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.53 35.0 2.65e-01 70.0% 69.4%
3cjlA00 3.10.20.850 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Protein of unknown function DUF3861 0.53 38.0 3.25e-01 80.0% 60.2%
1xffA00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.52 42.0 2.84e-01 100.0% 82.4%
2fe3A02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.52 42.0 4.07e-01 96.0% 96.5%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.51 40.0 2.71e-01 96.0% 87.0%
2jhnA01 3.30.310.20 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › DNA-3-methyladenine glycosylase AlkA, N-terminal domain 0.51 35.0 2.87e-01 76.0% 72.6%
6cc0A01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.51 39.0 2.94e-01 98.0% 33.5%
4efoA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.51 43.0 3.59e-01 98.0% 88.8%
5r0dB01 2.60.34.20 Mainly Beta › Sandwich › Substrate Binding Domain Of DNAk; Chain A, domain 1 › 0.50 35.0 2.65e-01 78.0% 34.3%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
8138 4123.1.1.1 few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.95 88.0 8.72e-01 98.0% 94.2%
8137 4123.1.1.1 few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.93 83.0 8.24e-01 98.0% 94.2%
146929 3115.3.1.1 a+b two layers › GP2-like › P56 › P56 › UDG-inhib_P56 0.78 54.0 5.19e-01 78.0% 64.3%
4029830 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.70 47.0 3.37e-01 72.0% 24.5%
3935205 382.1.1.0 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.68 51.0 3.91e-01 80.0% 34.2%
4463006 3115.2.1.0 a+b two layers › GP2-like › GP2 › GP2 0.67 46.0 4.84e-01 80.0% 82.2%
3730501 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.65 42.0 4.41e-01 84.0% 75.6%
4002159 1073.1.1.1 alpha arrays › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › Mitochondrial calcium uniporter (MCU) › MCU 0.64 46.0 2.83e-01 76.0% 25.6%
4995222 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.63 45.0 4.03e-01 78.0% 90.7%
3254286 221.1.1.44 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Rad60-SLD 0.62 42.0 3.55e-01 82.0% 40.9%
3352340 375.1.1.210 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › PF30904 0.62 46.0 4.48e-01 80.0% 100.0%
3285401 3986.2.1.0 a+b two layers › GTP-binding protein lepA C-terminal domain-like › Antitoxin Dmd › Antitoxin Dmd 0.61 44.0 3.92e-01 78.0% 53.3%
5010744 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.60 49.0 4.60e-01 98.0% 80.0%
3937781 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.60 44.0 2.94e-01 78.0% 21.0%
4945274 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 43.0 3.33e-01 98.0% 32.0%
7739 803.1.1.1 a+b duplicates or obligate multimers › Hypothetical protein YoaG › Hypothetical protein YoaG › Hypothetical protein YoaG › DUF1869 0.60 51.0 4.86e-01 98.0% 90.0%
4944520 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.60 42.0 2.83e-01 78.0% 40.9%
3704397 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.60 44.0 3.70e-01 82.0% 47.1%
3926235 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.59 40.0 3.54e-01 74.0% 45.0%
3596282 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.59 47.0 3.93e-01 92.0% 91.6%
5012895 3115.1.1.0 a+b two layers › GP2-like › RplX-like › RplX-like 0.59 44.0 4.30e-01 80.0% 85.5%
3679515 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.59 46.0 4.85e-01 98.0% 95.6%
3650990 274.1.1.44 a+b two layers › Pili subunits › Pili subunits › Pili subunits › DUF7804 0.59 43.0 3.25e-01 80.0% 32.3%
4013074 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.58 40.0 3.11e-01 80.0% 30.0%
5050596 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.58 40.0 3.58e-01 76.0% 51.4%
3526122 109.3.1.8 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.57 42.0 2.75e-01 82.0% 36.2%
3369564 130.1.1.39 alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › DUF7086 0.56 48.0 3.55e-01 100.0% 44.3%
3739576 327.11.2.27 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_Vigilin 0.56 36.0 3.59e-01 72.0% 61.8%
4986717 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.56 47.0 4.39e-01 98.0% 89.2%
3239822 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.55 40.0 3.04e-01 82.0% 30.8%
3781912 221.1.1.2 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › ubiquitin 0.55 41.0 3.72e-01 82.0% 100.0%
3349141 375.1.1.182 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DUF7086 0.55 46.0 3.46e-01 100.0% 44.3%
3384326 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.55 40.0 3.54e-01 100.0% 51.2%
4013484 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.55 47.0 3.18e-01 100.0% 66.3%
3292891 2003.1.5.121 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF1442 0.55 37.0 2.49e-01 72.0% 26.7%
3731895 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 37.0 3.48e-01 74.0% 85.5%
4846323 3115.1.1.1 a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.54 39.0 3.62e-01 82.0% 60.0%
3790710 109.3.1.162 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank, Ank_2, Ank_5 0.54 42.0 2.56e-01 100.0% 12.2%
3401531 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.54 42.0 2.53e-01 100.0% 11.7%
3915000 327.11.2.20 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › BICC1_KH 0.54 36.0 3.32e-01 70.0% 85.7%
4422146 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.54 38.0 2.57e-01 74.0% 50.2%
3885274 2004.1.1.364 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C 0.53 37.0 2.22e-01 74.0% 26.4%
3519959 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.53 36.0 3.41e-01 74.0% 93.8%
3918540 386.1.1.281 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF27082 0.53 35.0 3.72e-01 90.0% 87.5%
4085794 226.1.1.6 a+b two layers › POZ domain › POZ domain › POZ domain › SANBR_BTB 0.53 43.0 3.04e-01 100.0% 47.6%
3480000 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.53 37.0 2.39e-01 76.0% 33.2%
3305241 2003.1.5.153 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT, Methyltransf_25 0.53 40.0 2.76e-01 84.0% 38.9%
3935630 3346.1.1.0 a+b two layers › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 › N-terminal domain in ubiquitin-fold modifier 1 specific protease UfSP2 0.52 45.0 3.03e-01 100.0% 92.2%
3933688 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 45.0 2.69e-01 98.0% 28.7%
3649276 887.1.1.0 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e 0.52 38.0 3.04e-01 86.0% 96.7%
5074262 2484.1.1.22 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 0.52 41.0 2.90e-01 100.0% 26.1%
3971390 4033.1.1.6 alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › AidB_N 0.51 36.0 2.64e-01 80.0% 73.1%
4142311 109.4.1.1297 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TIMELESS, PF27570 0.50 40.0 2.25e-01 86.0% 26.8%