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E7_protein
Euk-VirBos_taurus_papillomavirus_12
E7_protein__YP_009175021__Bos_taurus_papillomavirus_12__1070324
Identity
- Accession:
- YP_009175021 ↗
- Protein ID:
- E7_protein
- Kingdom:
- euk
Quality
82.5
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Xipapillomavirus›
Bos_taurus_papillomavirus_12
TaxID: 1070324
Cluster
View cluster (135 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 38-88
Domain cluster:
rep: E7_protein__YP_009507312__Human_papillomavirus_204__1650736__D45-90
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00527.24 best | E7 | 46.8 | 3.70e-12 | 84.3% | 46.7% |
CATH (32)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ewlA00 | 3.30.160.330 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.92 | 78.0 | 7.56e-01 | 92.2% | 83.9% |
| 4kyzA00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.70 | 48.0 | 3.37e-01 | 72.5% | 40.1% |
| 2jl8102 | 3.30.160.850 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.65 | 42.0 | 4.45e-01 | 76.5% | 75.6% |
| 2l48A00 | 3.30.70.2030 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 44.0 | 3.74e-01 | 72.5% | 70.6% |
| 7ejoB01 | 3.30.2260.10 | Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary | 0.63 | 41.0 | 3.57e-01 | 70.6% | 42.2% |
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.62 | 42.0 | 3.50e-01 | 72.5% | 39.1% |
| 3p2aA01 | 2.30.30.380 | Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 | 0.61 | 37.0 | 4.24e-01 | 92.2% | 88.9% |
| 3s8sA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.60 | 42.0 | 3.41e-01 | 76.5% | 64.5% |
| 2jvfA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.60 | 41.0 | 3.42e-01 | 72.5% | 42.6% |
| 5u3fB01 | 3.30.470.10 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain | 0.59 | 43.0 | 3.18e-01 | 78.4% | 42.9% |
| 2gupA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.59 | 40.0 | 3.27e-01 | 70.6% | 40.2% |
| 4lmyA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.58 | 46.0 | 4.60e-01 | 92.2% | 96.3% |
| 2kgfA00 | 1.10.375.10 | Mainly Alpha › Orthogonal Bundle › Human Immunodeficiency Virus Type 1 Capsid Protein › Human Immunodeficiency Virus Type 1 Capsid Protein | 0.58 | 39.0 | 2.94e-01 | 70.6% | 47.1% |
| 2xauA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 41.0 | 2.82e-01 | 74.5% | 77.0% |
| 2uvaG01 | 1.20.1050.120 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 47.0 | 3.63e-01 | 100.0% | 82.4% |
| 4mtnA01 | 3.30.1480.10 | Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain | 0.56 | 42.0 | 3.57e-01 | 86.3% | 96.8% |
| 6eudA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 37.0 | 2.66e-01 | 70.6% | 73.5% |
| 4mtdA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.55 | 45.0 | 4.31e-01 | 98.0% | 88.9% |
| 1l1lA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.55 | 46.0 | 2.70e-01 | 98.0% | 58.7% |
| 2dafA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.54 | 38.0 | 3.42e-01 | 76.5% | 96.1% |
| 5ffiE00 | 3.10.20.30 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain | 0.54 | 36.0 | 2.96e-01 | 76.5% | 35.3% |
| 3w1yB00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.54 | 36.0 | 2.92e-01 | 70.6% | 54.8% |
| 6zwwC01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 38.0 | 2.73e-01 | 78.4% | 74.0% |
| 2hj1A00 | 3.10.20.280 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like | 0.53 | 37.0 | 3.28e-01 | 76.5% | 48.1% |
| 1wmhA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 36.0 | 3.07e-01 | 70.6% | 90.4% |
| 2fe3A02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.53 | 43.0 | 4.21e-01 | 98.0% | 96.5% |
| 5sviB00 | 3.30.40.100 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.52 | 39.0 | 3.93e-01 | 84.3% | 79.2% |
| 1rzmA01 | 3.30.70.1140 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Phospho-2-dehydro-3-deoxyheptonate aldolase; domain 1 | 0.52 | 36.0 | 3.24e-01 | 76.5% | 73.8% |
| 2pe4A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.52 | 44.0 | 2.66e-01 | 100.0% | 79.6% |
| 2m1mA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.52 | 35.0 | 2.79e-01 | 70.6% | 34.6% |
| 2xigA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.51 | 41.0 | 4.04e-01 | 96.1% | 96.4% |
| 2dzmA01 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.50 | 32.0 | 2.94e-01 | 76.5% | 44.4% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8138 | 4123.1.1.1 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 | 0.95 | 82.0 | 8.21e-01 | 92.2% | 90.4% |
| 8137 | 4123.1.1.1 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 | 0.92 | 78.0 | 7.78e-01 | 92.2% | 90.4% |
| 3969006 | 3115.6.1.2 ↗ | a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597 | 0.71 | 46.0 | 4.84e-01 | 74.5% | 75.6% |
| 3935205 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.69 | 51.0 | 3.85e-01 | 74.5% | 31.7% |
| 4928795 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.65 | 43.0 | 4.52e-01 | 92.2% | 77.8% |
| 147620 | 4232.1.1.1 ↗ | few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 | 0.63 | 46.0 | 3.77e-01 | 86.3% | 42.3% |
| 4991835 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.62 | 47.0 | 4.81e-01 | 88.2% | 86.0% |
| 4937773 | 3115.1.1.1 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A | 0.62 | 43.0 | 4.18e-01 | 74.5% | 81.0% |
| 3388225 | 857.1.1.0 ↗ | a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like | 0.60 | 47.0 | 4.32e-01 | 86.3% | 66.2% |
| 5010744 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.59 | 46.0 | 4.36e-01 | 92.2% | 76.9% |
| 3360654 | 376.1.3.57 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf_ULT1 | 0.58 | 45.0 | 4.44e-01 | 88.2% | 90.9% |
| 3285877 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 36.0 | 2.37e-01 | 76.5% | 14.2% |
| 3708825 | 386.1.1.0 ↗ | few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers | 0.58 | 37.0 | 3.94e-01 | 76.5% | 75.6% |
| 4061421 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.57 | 37.0 | 3.24e-01 | 76.5% | 42.5% |
| 4422146 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.56 | 38.0 | 2.62e-01 | 72.5% | 50.2% |
| 4085524 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.55 | 34.0 | 3.73e-01 | 92.2% | 91.4% |
| 3679515 | 3115.1.1.1 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A | 0.53 | 36.0 | 3.72e-01 | 74.5% | 86.7% |
| 3588171 | 101.1.2.25 ↗ | alpha arrays › HTH › HTH › winged helix domain › FUR | 0.53 | 40.0 | 3.04e-01 | 90.2% | 37.2% |
| 3737908 | 221.1.1.94 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › AIP3 | 0.52 | 35.0 | 3.06e-01 | 70.6% | 46.3% |
| 3317451 | 375.10.1.3 ↗ | few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha › zf_DPOE_2 | 0.51 | 36.0 | 3.38e-01 | 92.2% | 60.0% |