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E7_protein
Euk-VirBos_taurus_papillomavirus_20
E7_protein__YP_009272607__Bos_taurus_papillomavirus_20__1887218
Identity
- Accession:
- YP_009272607 ↗
- Protein ID:
- E7_protein
- Kingdom:
- euk
Quality
83.0
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Bos_taurus_papillomavirus_20
TaxID: 1887218
Cluster
View cluster (135 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 41-91
Domain cluster:
rep: transforming_protein_E7__NP_041326__Human_papillomavirus_type_16__333760__D50-96
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00527.24 best | E7 | 39.5 | 7.00e-10 | 84.3% | 46.7% |
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ewlA00 | 3.30.160.330 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.92 | 78.0 | 7.56e-01 | 92.2% | 83.9% |
| 5yppA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.72 | 50.0 | 4.20e-01 | 74.5% | 74.4% |
| 4kyzA00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.69 | 48.0 | 3.33e-01 | 72.5% | 40.1% |
| 2jheA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.67 | 47.0 | 4.11e-01 | 74.5% | 77.8% |
| 7ejoB01 | 3.30.2260.10 | Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary | 0.67 | 43.0 | 3.68e-01 | 70.6% | 41.0% |
| 1fx2A00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.66 | 45.0 | 2.96e-01 | 72.5% | 31.5% |
| 2jl8102 | 3.30.160.850 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.65 | 44.0 | 4.60e-01 | 86.3% | 80.0% |
| 2l48A00 | 3.30.70.2030 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 43.0 | 3.70e-01 | 72.5% | 70.6% |
| 2jxtA01 | 3.10.20.10 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.62 | 43.0 | 3.79e-01 | 74.5% | 53.9% |
| 3eytB00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.62 | 40.0 | 2.84e-01 | 72.5% | 22.1% |
| 1vwxH02 | 3.90.930.12 | Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 | 0.61 | 42.0 | 3.40e-01 | 72.5% | 87.4% |
| 2xauA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 41.0 | 2.81e-01 | 70.6% | 76.0% |
| 3s8sA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.60 | 43.0 | 3.44e-01 | 76.5% | 63.6% |
| 5u3fB01 | 3.30.470.10 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain | 0.59 | 43.0 | 3.16e-01 | 78.4% | 42.9% |
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.59 | 39.0 | 3.35e-01 | 72.5% | 39.1% |
| 4lmyA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.58 | 46.0 | 4.55e-01 | 90.2% | 96.3% |
| 2jvfA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.58 | 40.0 | 3.34e-01 | 72.5% | 41.5% |
| 4llgM00 | 3.10.20.510 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › RNA polymerase inhibitor | 0.58 | 40.0 | 4.03e-01 | 74.5% | 74.0% |
| 2uvaG01 | 1.20.1050.120 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 48.0 | 3.67e-01 | 100.0% | 83.1% |
| 3p2aA01 | 2.30.30.380 | Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 | 0.58 | 36.0 | 4.13e-01 | 86.3% | 91.7% |
| 2kgfA00 | 1.10.375.10 | Mainly Alpha › Orthogonal Bundle › Human Immunodeficiency Virus Type 1 Capsid Protein › Human Immunodeficiency Virus Type 1 Capsid Protein | 0.57 | 38.0 | 2.88e-01 | 70.6% | 47.1% |
| 4e1pA00 | 3.30.60.230 | Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain | 0.55 | 42.0 | 4.13e-01 | 96.1% | 76.4% |
| 4mtdA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.55 | 45.0 | 4.28e-01 | 98.0% | 88.9% |
| 2hj1A00 | 3.10.20.280 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like | 0.55 | 38.0 | 3.35e-01 | 76.5% | 48.1% |
| 1l1lA01 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.54 | 46.0 | 2.67e-01 | 98.0% | 68.9% |
| 3h20A01 | 3.30.1490.240 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain | 0.54 | 36.0 | 3.38e-01 | 74.5% | 53.0% |
| 2fe3A02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.54 | 43.0 | 4.26e-01 | 96.1% | 96.5% |
| 2bm0A03 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.54 | 34.0 | 3.47e-01 | 72.5% | 64.7% |
| 2hiyA01 | 3.30.70.1280 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › SP0830-like domains | 0.54 | 36.0 | 3.18e-01 | 72.5% | 72.7% |
| 4pofA03 | 2.20.28.10 | Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › | 0.54 | 36.0 | 3.64e-01 | 92.2% | 72.0% |
| 5sviB00 | 3.30.40.100 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › | 0.53 | 39.0 | 3.95e-01 | 84.3% | 79.2% |
| 1wmhA00 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.53 | 36.0 | 3.08e-01 | 72.5% | 92.8% |
| 5r0dB01 | 2.60.34.20 | Mainly Beta › Sandwich › Substrate Binding Domain Of DNAk; Chain A, domain 1 › | 0.52 | 35.0 | 2.61e-01 | 72.5% | 69.9% |
| 1rzmA01 | 3.30.70.1140 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Phospho-2-dehydro-3-deoxyheptonate aldolase; domain 1 | 0.51 | 35.0 | 3.17e-01 | 74.5% | 73.8% |
| 4mtnA01 | 3.30.1480.10 | Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain | 0.51 | 39.0 | 3.41e-01 | 94.1% | 98.9% |
| 5ffiE00 | 3.10.20.30 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain | 0.51 | 35.0 | 2.88e-01 | 72.5% | 99.0% |
| 1ln0A00 | 3.40.1440.10 | Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease | 0.51 | 39.0 | 3.32e-01 | 88.2% | 94.6% |
| 2xigA02 | 3.30.1490.190 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain | 0.51 | 40.0 | 3.98e-01 | 96.1% | 96.4% |
| 2z73B01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 44.0 | 2.66e-01 | 100.0% | 33.2% |
| 2pe4A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.50 | 43.0 | 2.60e-01 | 100.0% | 79.6% |
| 4wiwA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.50 | 34.0 | 3.21e-01 | 72.5% | 91.3% |
| 6uqjA02 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.50 | 34.0 | 2.12e-01 | 70.6% | 18.6% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8138 | 4123.1.1.1 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 | 0.92 | 79.0 | 7.94e-01 | 92.2% | 90.4% |
| 8137 | 4123.1.1.1 ↗ | few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 | 0.92 | 78.0 | 7.78e-01 | 92.2% | 90.4% |
| 4004704 | 3115.6.1.2 ↗ | a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597 | 0.70 | 46.0 | 4.80e-01 | 74.5% | 75.6% |
| 4937773 | 3115.1.1.1 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A | 0.62 | 44.0 | 4.24e-01 | 74.5% | 81.0% |
| 4991835 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.62 | 47.0 | 4.83e-01 | 88.2% | 86.0% |
| 3271498 | 304.121.1.1 ↗ | a+b two layers › Alpha-beta plaits › SP0830-like › SP0830-like › DUF1697 | 0.61 | 43.0 | 3.64e-01 | 76.5% | 73.3% |
| 3258276 | 4081.1.1.2 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › VIT | 0.61 | 39.0 | 2.62e-01 | 74.5% | 15.1% |
| 3739283 | 3322.1.1.1 ↗ | alpha bundles › N-terminal domain in fatty acid synthase subunit beta › N-terminal domain in fatty acid synthase subunit beta › N-terminal domain in fatty acid synthase subunit beta › FAS_N | 0.60 | 51.0 | 3.86e-01 | 100.0% | 86.9% |
| 5010744 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.58 | 45.0 | 4.32e-01 | 92.2% | 78.5% |
| 5016960 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.58 | 38.0 | 4.01e-01 | 92.2% | 77.8% |
| 3816922 | 4081.1.1.0 ↗ | beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related | 0.58 | 39.0 | 2.48e-01 | 70.6% | 63.9% |
| 3360654 | 376.1.3.57 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf_ULT1 | 0.58 | 44.0 | 4.36e-01 | 88.2% | 90.9% |
| 5067865 | 3115.1.1.0 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like | 0.58 | 42.0 | 3.80e-01 | 86.3% | 57.1% |
| 3679515 | 3115.1.1.1 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A | 0.57 | 43.0 | 4.50e-01 | 92.2% | 91.1% |
| 3369564 | 130.1.1.39 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › DUF7086 | 0.56 | 45.0 | 3.38e-01 | 92.2% | 42.9% |
| None | — | 0.55 | 44.0 | 2.82e-01 | 100.0% | 68.1% | |
| 3242889 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.52 | 35.0 | 3.07e-01 | 76.5% | 41.2% |
| 3637444 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.52 | 44.0 | 2.86e-01 | 100.0% | 87.8% |
| 5074262 | 2484.1.1.22 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 | 0.51 | 39.0 | 2.76e-01 | 94.1% | 25.0% |