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E7_protein

Euk-Vir

Human_papillomavirus_204

E7_protein__YP_009507312__Human_papillomavirus_204__1650736

Identity

Accession:
YP_009507312 ↗
Protein ID:
E7_protein
Kingdom:
euk

Quality

79.8 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Mupapillomavirus› Human_papillomavirus_204

TaxID: 1650736

Cluster

View cluster (135 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 45-90
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00527.24 best E7 28.7 1.70e-06 93.5% 47.8%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.90 66.0 7.04e-01 78.3% 92.3%
2ewlA00 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.89 78.0 7.35e-01 100.0% 83.9%
3buxB03 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.72 51.0 4.21e-01 82.6% 40.7%
2jl8102 3.30.160.850 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.71 47.0 4.78e-01 89.1% 71.1%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.69 50.0 4.16e-01 80.4% 76.5%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.66 48.0 3.88e-01 80.4% 40.2%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.64 47.0 3.25e-01 80.4% 22.2%
3i3lA02 3.30.390.160 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.62 41.0 2.99e-01 71.7% 24.8%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.62 53.0 4.91e-01 100.0% 81.7%
2uvaG01 1.20.1050.120 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 51.0 3.78e-01 100.0% 78.7%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.62 44.0 3.65e-01 80.4% 39.4%
1k8rB00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.61 44.0 3.60e-01 76.1% 48.8%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.61 41.0 3.97e-01 78.3% 58.2%
3eytB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.61 45.0 3.19e-01 84.8% 24.0%
2gupA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 44.0 3.58e-01 80.4% 42.3%
5yvxA00 3.30.40.100 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.60 49.0 4.58e-01 93.5% 71.7%
1fx2A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.60 42.0 2.78e-01 80.4% 31.1%
4lmyA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.60 49.0 4.74e-01 100.0% 98.1%
3p2aA01 2.30.30.380 Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24 0.58 39.0 4.29e-01 93.5% 91.7%
2czrA02 3.90.79.30 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › TBP-interacting protein, C-terminal domain 0.58 35.0 2.63e-01 76.1% 20.0%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.57 43.0 3.63e-01 91.3% 96.8%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.57 42.0 3.62e-01 84.8% 49.4%
5sviB00 3.30.40.100 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › 0.56 45.0 4.35e-01 93.5% 77.4%
3fdfA02 6.10.140.550 Special › Helix non-globular › Helix Hairpins › 0.56 37.0 3.57e-01 80.4% 57.1%
4mtdA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.56 45.0 4.16e-01 97.8% 84.1%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.56 45.0 2.62e-01 95.7% 22.7%
5ffiE00 3.10.20.30 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain 0.55 39.0 3.12e-01 82.6% 35.3%
2fe3A02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.55 44.0 4.23e-01 97.8% 93.0%
6uqjA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.55 40.0 2.46e-01 82.6% 69.9%
2pe4A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 45.0 2.67e-01 100.0% 76.0%
1wghA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 39.0 3.29e-01 84.8% 44.6%
6eudA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 39.0 2.70e-01 78.3% 74.7%
7dvrA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 44.0 3.18e-01 95.7% 54.6%
1wmhA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 40.0 3.34e-01 82.6% 100.0%
2xigA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.53 42.0 4.08e-01 97.8% 96.4%
2pw9C02 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.53 37.0 3.53e-01 84.8% 60.3%
6bq9A02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.52 37.0 3.19e-01 82.6% 77.7%
4ehoB03 3.30.450.270 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PHY domain 0.52 39.0 2.72e-01 87.0% 31.8%
1mhyD00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.51 45.0 2.52e-01 100.0% 8.8%
4rayA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.50 40.0 3.96e-01 95.7% 96.0%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
8138 4123.1.1.1 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.91 82.0 7.90e-01 100.0% 90.4%
3337279 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.79 56.0 6.18e-01 100.0% 100.0%
4928795 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.67 48.0 4.84e-01 95.7% 77.8%
3649366 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.65 43.0 3.60e-01 78.3% 37.6%
4991835 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.62 51.0 5.02e-01 97.8% 88.0%
4294893 375.1.1.240 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Zn_ribbon_Brz 0.61 51.0 4.74e-01 95.7% 88.3%
3360654 376.1.3.57 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › zf_ULT1 0.61 49.0 4.77e-01 97.8% 92.7%
5010744 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.59 48.0 4.45e-01 100.0% 83.1%
2793102 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.59 39.0 4.25e-01 95.7% 94.1%
4580635 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.59 42.0 2.61e-01 76.1% 50.7%
3498497 301.7.1.0 ↗ a+b three layers › Bacillus chorismate mutase-like › YjgF-like › YjgF-like 0.59 41.0 2.70e-01 76.1% 30.7%
3308207 5.1.3.22 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › GSDH 0.58 41.0 2.60e-01 76.1% 88.1%
3709652 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.57 42.0 3.71e-01 80.4% 94.3%
3233262 706.1.1.0 ↗ beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE 0.57 38.0 4.16e-01 71.7% 91.4%
3798829 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.57 40.0 2.63e-01 76.1% 44.4%
3253565 386.1.1.0 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.56 38.0 4.16e-01 97.8% 94.3%
3596419 375.1.1.77 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › DUF4379 0.56 38.0 3.99e-01 82.6% 82.5%
3285877 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 38.0 2.48e-01 84.8% 14.7%
3739576 327.11.2.27 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_Vigilin 0.56 40.0 3.80e-01 80.4% 63.6%
3723914 327.11.2.40 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF31052 0.55 41.0 3.68e-01 80.4% 92.3%
3610148 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 40.0 2.70e-01 80.4% 26.1%
3649913 5050.1.1.58 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C 0.54 41.0 2.79e-01 82.6% 76.5%
3839446 2002.1.1.52 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Peptidase_U32 0.54 44.0 2.72e-01 97.8% 92.0%
4083451 192.2.1.20 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ASNSD1-SEP 0.54 35.0 2.91e-01 80.4% 36.3%
3988478 857.1.1.1 ↗ a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.54 42.0 3.45e-01 95.7% 51.0%
3588171 101.1.2.25 ↗ alpha arrays › HTH › HTH › winged helix domain › FUR 0.53 43.0 3.20e-01 100.0% 38.6%
4929843 4123.1.1.0 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like 0.53 42.0 4.16e-01 93.5% 88.0%
3918540 386.1.1.281 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF27082 0.53 36.0 3.75e-01 95.7% 87.5%
3933447 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.52 38.0 3.02e-01 80.4% 41.9%
3587660 857.1.1.1 ↗ a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.51 42.0 3.11e-01 97.8% 37.1%
3970701 560.1.1.0 ↗ few secondary structure elements › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain 0.51 33.0 3.52e-01 78.3% 72.5%
4016025 2485.1.1.39 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › GST_N_2 0.51 35.0 2.73e-01 76.1% 29.6%
4944397 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.51 34.0 3.36e-01 82.6% 64.0%