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E7_protein

Euk-Vir

Giraffa_camelopardalis_papillomavirus_1

E7_protein__YP_009508735__Giraffa_camelopardalis_papillomavirus_1__1922325

Identity

Accession:
YP_009508735 ↗
Protein ID:
E7_protein
Kingdom:
euk

Quality

72.1 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Deltapapillomavirus› Giraffa_camelopardalis_papillomavirus_1

TaxID: 1922325

Cluster

View cluster (135 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 52-98
PDB
Domain cluster: rep: transforming_protein_E7__NP_041326__Human_papillomavirus_type_16__333760__D50-96
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00527.24 best E7 34.0 3.70e-08 95.7% 46.7%
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b9dA01 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.91 67.0 7.28e-01 78.7% 94.9%
2ewlA00 3.30.160.330 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.90 80.0 7.58e-01 100.0% 83.9%
5yppA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.74 57.0 4.62e-01 85.1% 76.7%
2jheA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 53.0 4.45e-01 83.0% 79.0%
3h95A02 4.10.80.100 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › 0.70 44.0 4.94e-01 70.2% 100.0%
3msyA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.68 55.0 4.29e-01 95.7% 80.2%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.66 50.0 3.45e-01 83.0% 41.3%
1vwxr00 3.30.390.110 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.66 48.0 3.68e-01 83.0% 35.2%
2dt9A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 48.0 4.14e-01 80.9% 86.1%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.65 47.0 4.32e-01 85.1% 58.5%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.64 48.0 4.18e-01 85.1% 56.6%
2vd3A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 46.0 4.13e-01 85.1% 82.4%
1neiA00 3.30.160.220 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YoaG 0.63 52.0 4.94e-01 100.0% 81.7%
2hj1A00 3.10.20.280 Alpha Beta › Roll › Ubiquitin-like (UB roll) › RnfH-like 0.62 46.0 3.97e-01 85.1% 50.6%
3k0yA02 2.60.40.2370 Mainly Beta › Sandwich › Immunoglobulin-like › NigD-like, C-terminal beta sandwich domain 0.59 42.0 3.14e-01 78.7% 60.2%
8b4hA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 48.0 3.44e-01 100.0% 80.9%
3e0jB00 3.90.1030.20 Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain 0.59 40.0 2.93e-01 74.5% 23.8%
4lmyA02 3.30.1490.190 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Ferric-uptake regulator, C-terminal dimerisarion domain 0.59 48.0 4.66e-01 100.0% 100.0%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.59 43.0 3.52e-01 80.9% 42.6%
6tdxG01 3.40.1380.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit 0.58 40.0 2.62e-01 72.3% 83.2%
2y3aA01 3.10.20.770 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.58 43.0 2.69e-01 100.0% 13.6%
3ulbA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.57 41.0 3.58e-01 80.9% 48.2%
1qxfA00 2.20.25.100 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › Ribosomal protein S27 0.57 39.0 3.70e-01 100.0% 58.6%
1vigA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.57 41.0 3.74e-01 83.0% 95.8%
7bi2A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.56 40.0 3.16e-01 78.7% 76.6%
2xauA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 39.0 2.73e-01 76.6% 76.0%
1ydmB00 3.40.50.10420 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NagB/RpiA/CoA transferase-like 0.56 38.0 2.63e-01 72.3% 22.0%
4efoA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.55 43.0 3.52e-01 87.2% 86.5%
2pe4A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 45.0 2.70e-01 97.9% 79.1%
4mtnA01 3.30.1480.10 Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain 0.54 42.0 3.55e-01 95.7% 100.0%
6zwwC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 38.0 2.62e-01 74.5% 70.5%
1dgsA02 3.30.1490.70 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.54 40.0 3.31e-01 89.4% 41.1%
5axmB00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.53 43.0 2.87e-01 100.0% 87.0%
3t5tB01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.53 38.0 2.43e-01 78.7% 24.4%
1rzmA01 3.30.70.1140 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Phospho-2-dehydro-3-deoxyheptonate aldolase; domain 1 0.52 36.0 3.11e-01 72.3% 100.0%
4hjwA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.52 39.0 2.35e-01 85.1% 86.1%
6cc0A01 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.52 41.0 2.99e-01 100.0% 31.7%
6eudA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 37.0 2.63e-01 78.7% 74.7%
3bzwF00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.52 37.0 2.40e-01 78.7% 36.6%
4cbgD02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 37.0 2.58e-01 76.6% 42.9%
5cm2Z00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 35.0 2.42e-01 72.3% 57.1%
1ln0A00 3.40.1440.10 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease 0.52 40.0 3.46e-01 100.0% 97.8%
5xpcA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.51 39.0 3.30e-01 87.2% 80.0%
3i3lA02 3.30.390.160 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.51 38.0 2.97e-01 89.4% 84.8%
3o2iA00 3.30.70.2710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 36.0 3.17e-01 89.4% 55.9%
3pxpA02 3.30.450.180 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.50 37.0 2.54e-01 83.0% 85.4%
1c9fA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.50 34.0 2.99e-01 78.7% 40.2%
7w3rB01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.50 42.0 2.58e-01 100.0% 79.9%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
8138 4123.1.1.1 ↗ few secondary structure elements › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 C-terminal domain-like › E7 0.92 83.0 8.08e-01 100.0% 90.4%
4153244 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 46.0 4.18e-01 83.0% 94.3%
4995222 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.63 46.0 4.11e-01 83.0% 90.7%
4846323 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.63 47.0 4.25e-01 85.1% 58.6%
3259162 3351.1.1.1 ↗ a/b three-layered sandwiches › Atg7 N-terminal domain-like › N-terminal domain in E1 enzyme Atg7 › N-terminal domain in E1 enzyme Atg7 › ATG7_N 0.63 43.0 3.22e-01 72.3% 34.4%
7739 803.1.1.1 ↗ a+b duplicates or obligate multimers › Hypothetical protein YoaG › Hypothetical protein YoaG › Hypothetical protein YoaG › DUF1869 0.63 52.0 4.94e-01 100.0% 81.7%
5030944 1.1.3.0 ↗ beta barrels › cradle loop barrel › RIFT-related › AbrB 0.62 40.0 4.14e-01 70.2% 68.9%
3679515 3115.1.1.1 ↗ a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A 0.61 49.0 5.01e-01 97.9% 93.3%
5010744 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.61 49.0 4.58e-01 97.9% 75.4%
3182789 376.1.1.21 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 0.61 54.0 4.22e-01 100.0% 62.2%
3273838 2006.1.1.35 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Pex22_HAD-like 0.59 41.0 3.05e-01 74.5% 48.9%
4986717 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.59 49.0 4.51e-01 97.9% 87.7%
3785325 376.1.1.21 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-RING_2 0.59 51.0 4.18e-01 100.0% 60.0%
3650990 274.1.1.44 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits › DUF7804 0.59 43.0 3.29e-01 85.1% 32.3%
3233262 706.1.1.0 ↗ beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE 0.59 40.0 4.33e-01 72.3% 94.3%
3526122 109.3.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 0.58 45.0 2.90e-01 87.2% 36.2%
3907411 5001.1.1.111 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1, 7TM_GPCR_Srw 0.58 47.0 2.95e-01 100.0% 67.3%
3306468 868.1.1.1 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › CYTH 0.57 39.0 2.70e-01 72.3% 80.0%
3988478 857.1.1.1 ↗ a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like › ZapA 0.57 48.0 3.90e-01 100.0% 54.1%
3305241 2003.1.5.153 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT, Methyltransf_25 0.57 40.0 2.73e-01 76.6% 23.3%
3022542 2003.1.9.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.57 40.0 2.72e-01 78.7% 97.5%
5074262 2484.1.1.22 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 0.56 44.0 3.05e-01 97.9% 23.9%
3476221 2498.1.1.14 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M8 0.56 46.0 2.69e-01 100.0% 27.8%
3239822 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.56 41.0 3.14e-01 87.2% 30.8%
5050596 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.56 41.0 3.63e-01 83.0% 52.9%
4422146 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.55 38.0 2.54e-01 72.3% 48.8%
5018200 2004.1.1.220 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2 0.55 40.0 2.34e-01 80.9% 78.4%
4025162 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.55 43.0 3.50e-01 89.4% 77.9%
3880867 2484.1.1.145 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1_7 0.55 45.0 2.74e-01 100.0% 55.8%
3723914 327.11.2.40 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF31052 0.55 40.0 3.63e-01 78.7% 93.8%
3483729 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.55 42.0 3.17e-01 85.1% 79.2%
3710894 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 38.0 3.66e-01 85.1% 63.8%
3480000 5001.1.1.5 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.53 40.0 2.50e-01 85.1% 29.5%
4971999 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.53 40.0 2.94e-01 80.9% 76.8%
3486254 327.11.2.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.53 43.0 3.81e-01 100.0% 97.5%
3970701 560.1.1.0 ↗ few secondary structure elements › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain 0.53 34.0 3.66e-01 85.1% 77.5%
3918540 386.1.1.281 ↗ few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF27082 0.53 36.0 3.73e-01 95.7% 87.5%
3943219 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.52 37.0 2.59e-01 74.5% 72.9%
3254286 221.1.1.44 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Rad60-SLD 0.52 42.0 3.53e-01 95.7% 84.1%
3292891 2003.1.5.121 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF1442 0.52 37.0 2.47e-01 76.6% 26.7%
4024059 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.52 36.0 2.26e-01 74.5% 54.7%
1153578 75.1.1.1 ↗ beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase 0.51 41.0 3.75e-01 100.0% 87.1%
3933447 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.51 36.0 2.99e-01 83.0% 37.1%
3752139 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.51 44.0 3.50e-01 100.0% 96.9%
3810572 2003.1.5.26 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_28 0.51 40.0 2.37e-01 89.4% 19.3%
3824313 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.51 38.0 2.62e-01 87.2% 61.0%
4981949 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.50 41.0 3.53e-01 95.7% 93.8%