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EF057797.1__AAS38507.1__X__00060

Bact-Vir

EF057797.1__AAS38507.1__X__00060

Identity

Accession:
EF057797 ↗
Kingdom:
phage

Quality

88.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 3-100
PDB
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xcjA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.76 50.0 5.35e-01 96.9% 78.6%
2auwB02 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.74 43.0 4.97e-01 85.7% 80.0%
7xi5A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.73 39.0 5.06e-01 82.7% 100.0%
2kpjA01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.73 47.0 5.44e-01 94.9% 92.9%
4jcyA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.70 50.0 5.16e-01 98.0% 78.3%
3iylB02 1.10.2050.10 Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 0.66 54.0 4.84e-01 87.8% 73.1%
3hyuA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 55.0 4.95e-01 96.9% 90.1%
1gcvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 55.0 4.95e-01 96.9% 89.3%
7jveC01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.60 41.0 3.09e-01 100.0% 27.8%
1w36F02 1.10.10.160 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.60 46.0 4.67e-01 82.7% 99.0%
6dewA01 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 41.0 3.33e-01 72.4% 44.2%
4zqeA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.59 33.0 3.42e-01 86.7% 56.2%
1ichA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.56 45.0 4.78e-01 96.9% 100.0%
2a5yB01 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.56 48.0 4.65e-01 99.0% 88.1%
2bg1A01 3.90.1310.40 Alpha Beta › Alpha-Beta Complex › Penicillin-binding protein 2a (Domain 2) › 0.55 39.0 4.27e-01 73.5% 100.0%
1ymgA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.55 45.0 3.51e-01 91.8% 75.1%
2aj6A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 46.0 4.37e-01 93.9% 95.0%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 37.0 3.21e-01 71.4% 98.7%
4gx0A01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 35.0 3.51e-01 100.0% 65.0%
2nsfA01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.52 40.0 3.44e-01 81.6% 87.4%
1cqxA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 44.0 3.91e-01 96.9% 89.3%
4dhiB02 1.20.1300.20 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 0.51 41.0 3.68e-01 89.8% 96.6%
6n8eA04 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 42.0 3.29e-01 100.0% 38.8%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 36.0 3.25e-01 75.5% 70.1%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4649431 3524.1.1.2 alpha arrays › Uncharacterized protein encoded by cryptic prophage › Uncharacterized protein encoded by cryptic prophage › Uncharacterized protein encoded by cryptic prophage › PF29794 0.84 78.0 7.79e-01 96.9% 98.0%
5010377 101.1.4.3 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › HTH_3 0.78 51.0 5.78e-01 95.9% 92.9%
3587663 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.62 43.0 4.63e-01 99.0% 87.5%
3237659 524.1.1.1 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.60 41.0 3.57e-01 70.4% 94.7%
3278365 191.1.1.33 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_31 0.59 41.0 3.93e-01 72.4% 66.1%
4999162 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.58 34.0 4.02e-01 73.5% 86.2%
3442088 5059.1.1.3 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT 0.56 39.0 3.09e-01 70.4% 42.4%
3187484 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.56 38.0 2.87e-01 70.4% 58.0%
3499937 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.55 39.0 4.03e-01 73.5% 100.0%
4588387 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.55 42.0 4.20e-01 82.7% 100.0%
4125256 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.53 46.0 3.17e-01 98.0% 78.1%
4976855 142.1.1.52 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Rce1-like 0.53 34.0 3.94e-01 72.4% 91.4%
4009481 5050.1.1.10 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_2 0.52 38.0 2.95e-01 76.5% 68.7%
5060007 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.51 36.0 3.26e-01 74.5% 73.3%
3179160 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 35.0 2.83e-01 73.5% 83.9%
D2 medium residues 123-193
PDB
Domain cluster: representative
CATH (57)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.88 66.0 6.79e-01 83.1% 82.1%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.81 54.0 5.50e-01 83.1% 69.0%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.81 55.0 5.76e-01 76.1% 75.8%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 59.0 6.07e-01 76.1% 91.0%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.80 62.0 4.07e-01 81.7% 33.1%
3t9oB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.79 59.0 4.84e-01 77.5% 45.8%
1zkeA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 64.0 6.09e-01 85.9% 90.1%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 62.0 4.11e-01 81.7% 31.0%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.78 61.0 5.63e-01 81.7% 73.9%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.77 51.0 5.46e-01 83.1% 78.7%
2r40D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.77 67.0 4.63e-01 95.8% 49.4%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.74 67.0 4.80e-01 100.0% 80.0%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.74 65.0 5.60e-01 95.8% 70.9%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.74 57.0 4.15e-01 81.7% 32.2%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.74 47.0 4.45e-01 80.3% 54.1%
2ksfA00 1.20.120.620 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd, 0.73 53.0 4.60e-01 80.3% 50.5%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.73 61.0 5.14e-01 91.5% 59.3%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 55.0 4.46e-01 81.7% 43.8%
2np9A01 1.20.58.1300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 63.0 4.99e-01 93.0% 86.6%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.72 62.0 4.43e-01 94.4% 33.7%
7ae2A01 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.72 61.0 4.93e-01 94.4% 63.5%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.72 59.0 5.92e-01 88.7% 87.3%
1vp7A00 1.10.287.1040 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Exonuclease VII, small subunit 0.72 54.0 5.59e-01 80.3% 83.8%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.72 55.0 3.54e-01 81.7% 20.1%
6vq6G02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.70 53.0 3.90e-01 81.7% 32.6%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.70 61.0 4.84e-01 94.4% 49.6%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.70 61.0 4.69e-01 95.8% 60.9%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 51.0 3.46e-01 81.7% 21.9%
1ykhA00 6.10.140.200 Special › Helix non-globular › Helix Hairpins › 0.68 53.0 4.80e-01 83.1% 62.1%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.68 58.0 4.57e-01 95.8% 76.0%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.68 57.0 4.52e-01 95.8% 48.3%
5tprA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.67 51.0 3.64e-01 83.1% 28.7%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.66 45.0 4.84e-01 73.2% 86.4%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 50.0 4.21e-01 81.7% 50.8%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.66 49.0 4.79e-01 81.7% 71.6%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.65 46.0 4.84e-01 78.9% 88.3%
4adzA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.65 58.0 5.38e-01 98.6% 86.7%
4mt4A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.65 51.0 3.14e-01 85.9% 15.7%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 48.0 4.17e-01 83.1% 49.2%
2ktmA00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.63 41.0 4.21e-01 78.9% 69.1%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.63 53.0 5.10e-01 98.6% 92.9%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 46.0 4.17e-01 80.3% 64.4%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.62 50.0 4.13e-01 88.7% 49.2%
1u5eA01 6.10.250.220 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 41.0 4.46e-01 76.1% 94.3%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 44.0 4.10e-01 76.1% 62.1%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 48.0 4.16e-01 90.1% 83.9%
6g94A00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.59 51.0 3.94e-01 100.0% 52.3%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 50.0 3.91e-01 100.0% 44.2%
4am6A03 3.30.420.580 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.58 41.0 2.80e-01 77.5% 20.5%
1yq1A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 48.0 4.17e-01 95.8% 80.4%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 47.0 3.77e-01 94.4% 53.5%
3ic9A02 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.55 41.0 4.21e-01 80.3% 94.3%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.55 42.0 3.49e-01 83.1% 46.8%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 44.0 3.80e-01 94.4% 76.1%
1k90B03 1.20.140.60 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.51 45.0 3.88e-01 100.0% 64.3%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 42.0 3.42e-01 94.4% 57.2%
4gf0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 41.0 3.63e-01 94.4% 82.3%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3232990 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.87 61.0 5.99e-01 81.7% 68.0%
3601853 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.83 65.0 4.97e-01 81.7% 42.8%
4987684 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.82 64.0 5.08e-01 81.7% 44.6%
4541195 3755.3.1.470 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB 0.81 64.0 5.04e-01 81.7% 55.4%
3493417 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.81 59.0 4.44e-01 81.7% 33.8%
4581983 5086.1.1.13 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › T3SSipB 0.81 63.0 4.90e-01 81.7% 51.4%
3631429 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.81 61.0 4.55e-01 83.1% 35.0%
3968997 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.81 63.0 5.00e-01 81.7% 50.0%
3633320 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.80 62.0 4.06e-01 81.7% 24.1%
3970512 5086.1.1.189 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CzcB 0.80 58.0 5.75e-01 76.1% 81.3%
4109644 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 61.0 4.78e-01 84.5% 40.7%
3698165 192.15.1.77 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › OST3_OST6 0.77 58.0 4.92e-01 95.8% 49.6%
3880178 192.8.1.92 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CUPID 0.77 63.0 6.06e-01 85.9% 76.2%
4258322 5086.1.1.189 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CzcB 0.77 59.0 6.01e-01 80.3% 88.6%
2526360 109.62.1.1 alpha superhelices › Repetitive alpha hairpins › AFF4 C-terminal homology domain › AFF4 C-terminal homology domain › AFF4_CHD 0.75 57.0 4.50e-01 87.3% 40.1%
5000698 604.38.1.0 alpha bundles › Spectrin repeat-like › Legionella effector SdeA 3-helical bundle › Legionella effector SdeA 3-helical bundle 0.75 58.0 5.03e-01 81.7% 55.2%
3664301 5069.1.3.60 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › OST3_OST6 0.75 56.0 4.73e-01 84.5% 48.7%
3809145 5076.2.1.10 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 0.75 66.0 4.25e-01 94.4% 37.3%
3485540 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.74 58.0 4.29e-01 83.1% 34.9%
4279523 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.74 57.0 3.94e-01 81.7% 26.8%
3191400 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.74 57.0 4.59e-01 81.7% 44.6%
3891493 5054.1.1.61 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO 0.74 55.0 3.64e-01 78.9% 21.9%
3607086 4992.1.1.0 extended segments › RelB-like › RelB-like › RelB-like 0.73 53.0 5.10e-01 81.7% 67.5%
3368498 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.72 47.0 4.16e-01 83.1% 45.7%
3988454 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.72 56.0 5.65e-01 81.7% 88.6%
3702706 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.72 54.0 5.23e-01 81.7% 71.2%
3699463 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 54.0 3.83e-01 81.7% 26.5%
3967983 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.72 56.0 5.38e-01 83.1% 75.0%
3665862 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.72 61.0 5.09e-01 95.8% 55.0%
4013672 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.72 56.0 4.98e-01 83.1% 59.0%
3695102 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 59.0 3.57e-01 90.1% 20.7%
3482907 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.70 54.0 4.51e-01 80.3% 49.6%
3820220 109.4.1.585 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF627 0.70 56.0 4.18e-01 100.0% 35.4%
3965957 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.70 52.0 5.14e-01 81.7% 76.0%
4176828 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 50.0 5.04e-01 80.3% 75.7%
3277563 603.2.1.2 alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.69 56.0 4.56e-01 90.1% 47.7%
3473984 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.69 58.0 3.93e-01 91.5% 69.8%
3969814 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.69 52.0 5.11e-01 81.7% 76.0%
3463944 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.68 59.0 4.95e-01 95.8% 59.2%
3380124 109.4.1.1266 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm, ARM_PUB 0.67 57.0 3.63e-01 100.0% 18.4%
3971349 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.67 47.0 4.96e-01 74.6% 86.7%
4276261 604.12.1.67 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › eIF-3c_N 0.67 45.0 3.65e-01 70.4% 37.1%
3279013 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.67 50.0 3.28e-01 81.7% 56.0%
3359325 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.67 48.0 4.00e-01 77.5% 43.2%
3471120 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.67 49.0 5.19e-01 80.3% 84.6%
3608012 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.67 52.0 4.88e-01 83.1% 71.8%
4985493 3834.1.1.0 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain 0.66 50.0 3.39e-01 80.3% 23.1%
5059281 141.1.1.0 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases 0.66 57.0 3.89e-01 94.4% 30.6%
3697868 4207.1.1.65 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › DUF2985 0.66 52.0 3.72e-01 87.3% 31.4%
3455464 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.65 55.0 4.39e-01 97.2% 57.4%
4521994 5085.1.1.1 a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP 0.65 50.0 3.17e-01 84.5% 17.7%
4014485 5044.1.1.0 extended segments › PsbZ-like › PsbZ-like › PsbZ-like 0.65 50.0 4.52e-01 81.7% 74.7%
4951505 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.65 54.0 4.43e-01 90.1% 80.0%
3813837 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.65 48.0 4.78e-01 80.3% 76.0%
1388665 5085.1.1.1 a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP 0.64 51.0 3.13e-01 85.9% 15.6%
3531403 3914.1.1.0 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain 0.64 41.0 4.64e-01 74.6% 92.0%
4941353 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.64 57.0 4.78e-01 100.0% 59.1%
3901129 605.1.1.111 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › TMEM72 0.64 54.0 5.28e-01 100.0% 87.5%
3584009 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.63 48.0 3.34e-01 83.1% 24.1%
3974346 5085.1.1.1 a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP 0.63 53.0 3.20e-01 91.5% 17.6%
3098420 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.62 47.0 4.15e-01 83.1% 61.5%
3246139 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.62 55.0 3.58e-01 100.0% 70.1%
3757282 3352.1.1.25 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PIG-U 0.61 50.0 3.08e-01 88.7% 44.5%
3392851 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.61 52.0 3.76e-01 94.4% 71.5%
3601807 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 48.0 2.84e-01 94.4% 72.5%
3356998 109.4.1.81 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF-3c_N 0.56 50.0 2.95e-01 98.6% 36.6%