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EP1242L
Euk-VirAfrican_swine_fever_virus
EP1242L__YP_009703109__African_swine_fever_virus__10497
Identity
- Accession:
- YP_009703109 ↗
- Protein ID:
- EP1242L
- Kingdom:
- euk
Quality
70.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Asfuvirales›
Asfarviridae›
Asfivirus›
African_swine_fever_virus
TaxID: 10497
Cluster
View cluster (58 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 37-63_182-197_419-529
D2
medium
residues 64-181
Domain cluster:
rep: hypothetical_protein_MIV009R__YP_654581__Invertebrate_iridescent_virus_3__345201__D59-139
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04563.21 best | RNA_pol_Rpb2_1 | 37.1 | 3.60e-09 | 99.2% | 41.9% |
D3
medium
residues 198-275
D4
medium
residues 276-407
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1twfB04 | 3.90.1110.10 | Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 | 0.85 | 69.0 | 6.13e-01 | 100.0% | 62.1% |
| 4qiwB04 | 3.90.1110.10 | Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 | 0.83 | 64.0 | 5.91e-01 | 100.0% | 65.0% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4927221 | 4041.1.1.1 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 | 0.87 | 68.0 | 6.09e-01 | 100.0% | 60.6% |
| 3712713 | 4041.1.1.1 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 | 0.86 | 70.0 | 6.06e-01 | 100.0% | 58.4% |
| 4942210 | 4041.1.1.1 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 | 0.86 | 67.0 | 6.04e-01 | 100.0% | 62.4% |
| 4946073 | 4041.1.1.1 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 | 0.85 | 67.0 | 5.98e-01 | 100.0% | 61.1% |
| 4933430 | 4041.1.1.1 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 | 0.85 | 66.0 | 5.92e-01 | 100.0% | 60.6% |
| 4937698 | 4041.1.1.1 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 | 0.84 | 62.0 | 5.67e-01 | 100.0% | 60.6% |
| 4979468 | 4041.1.1.0 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase | 0.82 | 68.0 | 6.00e-01 | 100.0% | 62.8% |
| 5000298 | 4041.1.1.0 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase | 0.82 | 72.0 | 6.22e-01 | 100.0% | 62.6% |
| 4980641 | 4041.1.1.0 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase | 0.81 | 67.0 | 5.92e-01 | 100.0% | 61.6% |
| 4956725 | 4041.1.1.1 ↗ | a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 | 0.81 | 68.0 | 5.97e-01 | 100.0% | 62.2% |
| 4427252 | 3831.1.1.1 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI | 0.52 | 34.0 | 3.74e-01 | 87.1% | 83.8% |
| 5082892 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.51 | 34.0 | 3.20e-01 | 99.2% | 52.9% |
| 3926897 | 170.1.1.0 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C | 0.50 | 32.0 | 3.55e-01 | 75.0% | 81.0% |
D5
medium
residues 583-596_620-667
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04566.19 best | RNA_pol_Rpb2_4 | 33.2 | 6.40e-08 | 77.4% | 75.8% |
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1twfB05 | 3.90.1070.20 | Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › | 0.85 | 75.0 | 6.83e-01 | 96.8% | 96.3% |
| 4mt1A07 | 3.30.70.1440 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain | 0.65 | 50.0 | 4.33e-01 | 85.5% | 72.5% |
| 2b30A02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.63 | 55.0 | 4.61e-01 | 100.0% | 94.5% |
| 3jcmH04 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.60 | 46.0 | 4.35e-01 | 87.1% | 76.6% |
| 4c1sA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.60 | 43.0 | 2.66e-01 | 75.8% | 21.1% |
| 1fx2A00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.60 | 47.0 | 3.31e-01 | 93.5% | 57.9% |
| 2xmjA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 38.0 | 3.87e-01 | 74.2% | 69.8% |
| 4mtnA01 | 3.30.1480.10 | Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain | 0.57 | 38.0 | 3.41e-01 | 71.0% | 65.3% |
| 2kt2A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 43.0 | 4.20e-01 | 90.3% | 79.7% |
| 1c4zA01 | 3.90.1750.10 | Alpha Beta › Alpha-Beta Complex › Hect, E3 ligase catalytic domain fold › Hect, E3 ligase catalytic domains | 0.54 | 44.0 | 3.26e-01 | 88.7% | 61.3% |
| 4l8nA03 | 3.30.160.670 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.54 | 32.0 | 2.38e-01 | 95.2% | 22.0% |
| 4dpoB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 42.0 | 3.65e-01 | 98.4% | 54.5% |
| 7sk7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 41.0 | 2.86e-01 | 91.9% | 59.3% |
| 4akgA08 | 1.10.472.130 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain | 0.52 | 40.0 | 3.14e-01 | 100.0% | 35.3% |
| 5upiA01 | 2.70.98.30 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 | 0.52 | 43.0 | 3.20e-01 | 100.0% | 85.6% |
| 3p9aF00 | 1.10.132.80 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.52 | 43.0 | 3.44e-01 | 96.8% | 87.3% |
| 1k0rA01 | 3.30.1480.10 | Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain | 0.52 | 35.0 | 3.10e-01 | 72.6% | 69.7% |
| 5axmB00 | 3.30.70.3000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) | 0.51 | 45.0 | 3.06e-01 | 100.0% | 94.1% |
| 3lmmA03 | 3.30.565.60 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › | 0.51 | 42.0 | 3.22e-01 | 98.4% | 76.6% |
| 7lt2A01 | 3.30.460.90 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › | 0.51 | 38.0 | 2.71e-01 | 87.1% | 84.9% |
| 2itmB02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.51 | 43.0 | 2.93e-01 | 95.2% | 70.1% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 41.0 | 2.83e-01 | 100.0% | 81.2% |
| 1td6A02 | 3.30.1790.10 | Alpha Beta › 2-Layer Sandwich › hypothetical protein mp506/mpn330, domain 2 › hypothetical protein mp506/mpn330, domain 2 | 0.50 | 37.0 | 3.41e-01 | 95.2% | 57.6% |
| 2c7yA00 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.50 | 41.0 | 2.62e-01 | 100.0% | 88.7% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4937778 | 4961.1.1.1 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 | 0.90 | 70.0 | 7.42e-01 | 93.5% | 90.9% |
| 4942023 | 4961.1.1.1 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 | 0.90 | 67.0 | 7.11e-01 | 90.3% | 87.3% |
| 5073048 | 4961.1.1.1 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 | 0.90 | 84.0 | 7.28e-01 | 100.0% | 90.0% |
| 5027955 | 4961.1.1.1 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 | 0.89 | 69.0 | 7.30e-01 | 93.5% | 90.9% |
| 1511443 | 4961.1.1.1 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 | 0.88 | 80.0 | 6.98e-01 | 98.4% | 89.9% |
| 3891314 | 593.1.1.1 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 | 0.62 | 48.0 | 3.23e-01 | 85.5% | 28.7% |
| 4025741 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.60 | 51.0 | 3.78e-01 | 100.0% | 43.3% |
| 3789605 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.59 | 49.0 | 3.41e-01 | 98.4% | 58.4% |
| 3419693 | 109.4.1.1254 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, E_motif | 0.58 | 44.0 | 3.12e-01 | 83.9% | 26.2% |
| 4253201 | 109.3.1.136 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF2254 | 0.58 | 44.0 | 3.15e-01 | 85.5% | 30.2% |
| 5013701 | 3572.1.1.2 ↗ | a+b complex topology › Cascade subunit Csa5 › Cascade subunit Csa5 › Cascade subunit Csa5 › Cas_Csa5 | 0.57 | 45.0 | 3.84e-01 | 88.7% | 85.7% |
| 4837035 | 205.1.1.49 ↗ | a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_6, Fer4_7 | 0.56 | 40.0 | 4.46e-01 | 90.3% | 100.0% |
| 3929748 | 109.4.1.1303 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_PRP39_N, HAT_PRP39_C | 0.54 | 43.0 | 2.67e-01 | 88.7% | 57.6% |
| 4011647 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.54 | 41.0 | 2.77e-01 | 83.9% | 70.2% |
| 4329039 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.54 | 40.0 | 3.97e-01 | 85.5% | 81.4% |
| 3515089 | 304.3.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA | 0.53 | 40.0 | 3.94e-01 | 87.1% | 91.2% |
| 3634139 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 41.0 | 2.82e-01 | 90.3% | 26.7% |
| 3591105 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 41.0 | 2.85e-01 | 90.3% | 65.2% |
| 4971607 | 109.4.1.207 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_2 | 0.51 | 41.0 | 2.50e-01 | 91.9% | 15.9% |
| 3993316 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.51 | 42.0 | 2.71e-01 | 95.2% | 29.8% |
| 3180101 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 40.0 | 2.81e-01 | 91.9% | 61.1% |
| 3610777 | 109.4.1.1474 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_6, TPR_16 | 0.51 | 41.0 | 2.89e-01 | 91.9% | 65.7% |
| 3212403 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.50 | 41.0 | 2.77e-01 | 95.2% | 53.7% |
| 5049696 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.50 | 41.0 | 2.93e-01 | 98.4% | 83.1% |
| 3857827 | 109.4.1.2045 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_6 | 0.50 | 40.0 | 2.91e-01 | 91.9% | 51.5% |
D6
medium
residues 668-777
Domain cluster:
rep: EP1242L__YP_009704005__African_swine_fever_virus_Georgia_2007_1__874269__D673-773
D7
medium
residues 778-851
D8
medium
residues 891-966