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Eukaryotic_DNA_primase_small_subunit
Euk-VirMollivirus_sibericum_Viruses.
Eukaryotic_DNA_primase_small_subunit__YP_009165398__Mollivirus_sibericum_Viruses.__X
Identity
- Accession:
- YP_009165398 ↗
- Protein ID:
- Eukaryotic_DNA_primase_small_subunit
- Kingdom:
- euk
Quality
52.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 150-221
Domain cluster:
rep: hypothetical_protein_OtV2_070__YP_004063503__Ostreococcus_tauri_virus_2__696472__D1-57
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vk1A02 | 3.30.1760.10 | Alpha Beta › 2-Layer Sandwich › Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, domain 2 › Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, domain 2 | 0.67 | 56.0 | 4.71e-01 | 95.8% | 73.8% |
| 3ly1D01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.64 | 44.0 | 3.61e-01 | 70.8% | 89.9% |
| 1zpwX00 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 46.0 | 4.47e-01 | 100.0% | 73.2% |
| 1earA02 | 3.30.70.790 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain | 0.61 | 39.0 | 4.05e-01 | 93.1% | 69.6% |
| 1s7hA02 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 46.0 | 4.48e-01 | 100.0% | 75.6% |
| 1u8sA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.58 | 48.0 | 4.62e-01 | 98.6% | 80.2% |
| 3pm9A03 | 3.30.70.2190 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 50.0 | 4.26e-01 | 100.0% | 74.4% |
| 4lvnP00 | 3.30.70.2380 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 44.0 | 4.28e-01 | 98.6% | 77.8% |
| 4wxjB01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 46.0 | 3.65e-01 | 88.9% | 74.7% |
| 1iejA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 47.0 | 3.92e-01 | 100.0% | 90.9% |
| 1ibaA00 | 3.30.1360.60 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Glucose permease domain IIB | 0.56 | 39.0 | 3.84e-01 | 90.3% | 67.9% |
| 6a80A01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.55 | 43.0 | 3.72e-01 | 87.5% | 86.8% |
| 4qbuA03 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.55 | 41.0 | 4.29e-01 | 97.2% | 89.4% |
| 7o4xA01 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 47.0 | 4.31e-01 | 100.0% | 77.8% |
| 3s1tA02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.54 | 45.0 | 4.39e-01 | 98.6% | 86.3% |
| 4c0rA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 42.0 | 3.64e-01 | 88.9% | 84.4% |
| 1ffyA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.53 | 41.0 | 2.59e-01 | 84.7% | 89.6% |
| 3nwgA02 | 3.30.70.1710 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain | 0.53 | 43.0 | 4.00e-01 | 100.0% | 70.3% |
| 7zvsA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.52 | 40.0 | 3.09e-01 | 86.1% | 45.8% |
| 2od4B01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 43.0 | 4.11e-01 | 98.6% | 79.8% |
| 4ushA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 43.0 | 3.96e-01 | 100.0% | 69.9% |
| 2rdpA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 38.0 | 3.22e-01 | 86.1% | 72.1% |
| 2hzmG01 | 3.30.310.180 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › | 0.50 | 42.0 | 3.73e-01 | 100.0% | 77.4% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 11004 | 5103.1.1.1 ↗ | a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › DUF5603 | 0.67 | 55.0 | 5.00e-01 | 91.7% | 92.0% |
| 4323104 | 304.22.1.0 ↗ | a+b two layers › Alpha-beta plaits › Urease metallochaperone UreE, C-terminal domain › Urease metallochaperone UreE, C-terminal domain | 0.60 | 42.0 | 4.42e-01 | 91.7% | 88.3% |
| 4990834 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.59 | 35.0 | 3.95e-01 | 94.4% | 84.0% |
| 4219489 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.59 | 52.0 | 3.52e-01 | 100.0% | 28.7% |
| 3248261 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.58 | 43.0 | 4.38e-01 | 100.0% | 84.3% |
| 5059475 | 4961.1.1.0 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit | 0.58 | 48.0 | 4.63e-01 | 97.2% | 89.4% |
| 3840416 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.57 | 48.0 | 4.53e-01 | 98.6% | 76.7% |
| 3277566 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.57 | 44.0 | 4.36e-01 | 100.0% | 84.0% |
| 3411407 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.56 | 45.0 | 3.65e-01 | 88.9% | 65.5% |
| 5048300 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.56 | 45.0 | 4.08e-01 | 100.0% | 63.8% |
| 3741311 | 304.44.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 | 0.56 | 48.0 | 4.14e-01 | 100.0% | 60.8% |
| 4956135 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.55 | 38.0 | 4.12e-01 | 93.1% | 86.7% |
| 5006766 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.55 | 37.0 | 3.96e-01 | 98.6% | 81.7% |
| 5066439 | 304.3.1.14 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › DrrA1-3_C | 0.55 | 40.0 | 4.15e-01 | 95.8% | 89.2% |
| 3613200 | 304.134.1.0 ↗ | a+b two layers › Alpha-beta plaits › MJ1480-like › MJ1480-like | 0.55 | 47.0 | 4.47e-01 | 100.0% | 88.9% |
| 5019480 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.55 | 43.0 | 2.52e-01 | 87.5% | 16.0% |
| 3485628 | 304.1.1.1 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C | 0.54 | 46.0 | 3.67e-01 | 97.2% | 85.2% |
| 3287709 | 304.7.1.0 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors | 0.54 | 38.0 | 3.99e-01 | 97.2% | 86.2% |
| 4983407 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.54 | 39.0 | 4.02e-01 | 94.4% | 87.7% |
| 4487660 | 304.1.1.1 ↗ | a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C | 0.53 | 43.0 | 3.31e-01 | 98.6% | 35.8% |
| 3210164 | 304.44.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 | 0.53 | 46.0 | 3.67e-01 | 100.0% | 48.4% |
| 3594244 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.53 | 45.0 | 4.17e-01 | 100.0% | 79.6% |
| 4927527 | 304.5.1.1 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › P-II | 0.53 | 45.0 | 4.04e-01 | 100.0% | 80.9% |
| 3364276 | 904.1.1.0 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain | 0.53 | 33.0 | 3.67e-01 | 76.4% | 90.0% |
| 5005286 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.53 | 41.0 | 2.74e-01 | 84.7% | 77.0% |
| 3509991 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.53 | 43.0 | 4.18e-01 | 98.6% | 85.0% |
| 3976170 | 101.1.9.26 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain › YfeC-like | 0.52 | 34.0 | 3.49e-01 | 84.7% | 68.6% |
| 3789193 | 109.4.1.560 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mus7 | 0.52 | 43.0 | 2.56e-01 | 91.7% | 13.4% |
| 4973212 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.52 | 39.0 | 4.00e-01 | 97.2% | 92.3% |
| 4828343 | 2002.1.1.45 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd | 0.52 | 44.0 | 3.69e-01 | 98.6% | 87.9% |
| None | — | 0.52 | 44.0 | 2.64e-01 | 100.0% | 28.8% | |
| 4972474 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.51 | 44.0 | 2.58e-01 | 98.6% | 27.7% |
| 5050281 | 304.120.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI | 0.51 | 41.0 | 4.03e-01 | 95.8% | 82.5% |
| 5057564 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.51 | 41.0 | 3.17e-01 | 86.1% | 50.6% |
| 4031686 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.51 | 41.0 | 3.87e-01 | 94.4% | 83.2% |
| 3175163 | 304.9.1.74 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Nab6_mRNP_bdg | 0.51 | 42.0 | 3.80e-01 | 97.2% | 74.3% |
| 3946755 | 605.1.1.26 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF2058 | 0.50 | 39.0 | 3.41e-01 | 86.1% | 75.7% |
| 4384794 | 2002.1.1.45 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_31_2nd | 0.50 | 42.0 | 2.70e-01 | 100.0% | 55.1% |
D2
medium
residues 222-295_377-465_479-507
Domain cluster:
rep: primase__YP_009345453__Noumeavirus__1955558__D12-194
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF23162.2 best | AEP_C962R | 36.1 | 1.10e-08 | 78.6% | 68.7% |
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1b64A00 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.66 | 31.0 | 4.32e-01 | 71.4% | 92.3% |
| 1u8sA02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.64 | 30.0 | 4.33e-01 | 70.3% | 100.0% |
| 4djbA00 | 3.30.70.2870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 | 0.64 | 39.0 | 4.78e-01 | 72.4% | 97.5% |
| 2x3gA00 | 3.30.70.1910 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 34.0 | 4.25e-01 | 94.8% | 84.5% |
| 1l2mA00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.63 | 36.0 | 4.43e-01 | 95.8% | 89.0% |
| 3c19A01 | 3.30.70.1380 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transcriptional regulatory protein pf0864 domain like | 0.63 | 31.0 | 4.05e-01 | 70.8% | 85.9% |
| 2f5gA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.63 | 34.0 | 4.04e-01 | 71.4% | 75.4% |
| 2mq8A00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.63 | 34.0 | 4.29e-01 | 71.4% | 88.4% |
| 2fyxA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.62 | 39.0 | 4.58e-01 | 76.0% | 90.0% |
| 6h8oA00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.60 | 31.0 | 4.25e-01 | 96.9% | 98.9% |
| 3pfoA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 39.0 | 4.69e-01 | 71.4% | 98.4% |
| 1pbuA00 | 3.30.70.1010 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Translation elongation factor EF1B, gamma chain, conserved domain | 0.58 | 37.0 | 4.02e-01 | 97.4% | 75.9% |
| 1r9wA00 | 3.40.1310.10 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.57 | 32.0 | 3.72e-01 | 97.9% | 73.9% |
| 1m55A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.55 | 45.0 | 4.59e-01 | 97.9% | 87.0% |
| 2ausC02 | 3.30.2350.10 | Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › Pseudouridine synthase | 0.54 | 28.0 | 2.89e-01 | 72.4% | 47.9% |
| 1ekrA00 | 3.30.70.640 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Molybdopterin cofactor biosynthesis C (MoaC) domain | 0.54 | 36.0 | 4.13e-01 | 71.4% | 90.2% |
| 1rtzA00 | 3.30.70.560 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK | 0.54 | 41.0 | 4.53e-01 | 93.2% | 99.3% |
| 2hzmG01 | 3.30.310.180 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › | 0.53 | 33.0 | 4.01e-01 | 91.7% | 100.0% |
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.51 | 47.0 | 4.21e-01 | 100.0% | 89.5% |
| 3ih6E00 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.50 | 36.0 | 3.68e-01 | 71.9% | 92.3% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3212681 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.64 | 40.0 | 4.88e-01 | 70.3% | 99.2% |
| 4997627 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.64 | 42.0 | 4.91e-01 | 71.4% | 96.2% |
| 3733238 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.64 | 41.0 | 4.99e-01 | 71.4% | 100.0% |
| 3265794 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.63 | 28.0 | 3.70e-01 | 71.4% | 74.3% |
| 4994778 | 304.55.2.1 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp | 0.63 | 39.0 | 4.61e-01 | 93.8% | 90.0% |
| 3596400 | 304.51.1.0 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related | 0.62 | 39.0 | 4.68e-01 | 74.5% | 95.2% |
| 3628828 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.62 | 36.0 | 4.48e-01 | 71.4% | 93.0% |
| 141279 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.60 | 40.0 | 4.67e-01 | 71.4% | 96.9% |
| 3596967 | 304.46.1.0 ↗ | a+b two layers › Alpha-beta plaits › eEF1-gamma domain › eEF1-gamma domain | 0.58 | 36.0 | 3.95e-01 | 96.9% | 74.7% |
| 4943376 | 304.10.1.3 ↗ | a+b two layers › Alpha-beta plaits › RuBisCO, large subunit, small (N-terminal) domain › RuBisCO, large subunit, small (N-terminal) domain › RuBisCO_large | 0.57 | 33.0 | 4.16e-01 | 70.8% | 93.9% |
| 5075193 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.57 | 38.0 | 4.44e-01 | 70.8% | 98.5% |
| 4997823 | 304.25.1.1 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer | 0.56 | 39.0 | 4.50e-01 | 70.8% | 99.3% |
| 4133039 | 304.8.1.81 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P | 0.56 | 41.0 | 4.40e-01 | 96.9% | 86.7% |
| 4304749 | 304.8.1.81 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P | 0.56 | 40.0 | 3.61e-01 | 97.4% | 53.1% |
| 4094154 | 304.42.1.1 ↗ | a+b two layers › Alpha-beta plaits › Molybdenum cofactor biosynthesis protein C, MoaC › Molybdenum cofactor biosynthesis protein C, MoaC › MoaC | 0.56 | 36.0 | 4.20e-01 | 71.4% | 93.8% |
| 4007464 | 304.55.1.19 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Inovirus_Gp2 | 0.55 | 47.0 | 4.75e-01 | 96.9% | 91.6% |
| 1491756 | 304.55.1.9 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › PV_NSP1 | 0.53 | 49.0 | 4.47e-01 | 97.9% | 85.9% |
| 4447424 | 304.55.1.26 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › RepSA | 0.52 | 47.0 | 4.13e-01 | 96.9% | 84.4% |
| 4944441 | 309.1.2.0 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain | 0.51 | 36.0 | 3.89e-01 | 70.8% | 85.6% |
| 3968511 | 304.45.1.1 ↗ | a+b two layers › Alpha-beta plaits › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › HPPK | 0.51 | 41.0 | 4.28e-01 | 100.0% | 92.6% |
| 2834623 | 304.55.1.7 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_N | 0.51 | 40.0 | 4.25e-01 | 99.5% | 92.5% |
D3
medium
residues 508-580
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vw4L02 | 1.10.246.170 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.72 | 40.0 | 3.84e-01 | 79.5% | 47.1% |
| 2uyyA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.69 | 51.0 | 4.28e-01 | 78.1% | 98.4% |
| 5je8B02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.68 | 50.0 | 4.21e-01 | 79.5% | 96.9% |
| 1vpdA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.68 | 50.0 | 4.16e-01 | 79.5% | 94.7% |
| 3crvA02 | 1.10.275.30 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › | 0.68 | 49.0 | 4.31e-01 | 76.7% | 74.1% |
| 4dllB02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.67 | 50.0 | 4.19e-01 | 80.8% | 95.4% |
| 4ofzA01 | 1.20.58.1800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 46.0 | 4.02e-01 | 72.6% | 52.2% |
| 3w6zA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.66 | 50.0 | 4.25e-01 | 82.2% | 97.5% |
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.66 | 47.0 | 3.95e-01 | 75.3% | 50.8% |
| 7p5hB03 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.65 | 39.0 | 3.69e-01 | 76.7% | 49.4% |
| 3ccgA00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.64 | 45.0 | 3.32e-01 | 72.6% | 85.7% |
| 2o8pA00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.64 | 53.0 | 3.81e-01 | 93.2% | 32.4% |
| 4l9mA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.63 | 47.0 | 3.91e-01 | 80.8% | 64.7% |
| 2iw2A02 | 3.90.230.10 | Alpha Beta › Alpha-Beta Complex › Creatine Amidinohydrolase › Creatinase/methionine aminopeptidase superfamily | 0.63 | 43.0 | 2.87e-01 | 71.2% | 92.3% |
| 6q9jB02 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.62 | 38.0 | 3.60e-01 | 76.7% | 50.0% |
| 1h0hA02 | 3.40.50.740 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.62 | 44.0 | 3.10e-01 | 75.3% | 92.5% |
| 4y97D00 | 1.10.3200.20 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › DNA Polymerase alpha, zinc finger | 0.62 | 46.0 | 3.48e-01 | 78.1% | 83.1% |
| 3g0oA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.61 | 48.0 | 4.07e-01 | 84.9% | 90.1% |
| 4g26A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 45.0 | 2.98e-01 | 79.5% | 44.3% |
| 4f92B10 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.60 | 44.0 | 3.62e-01 | 80.8% | 91.6% |
| 3tm8B00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.59 | 47.0 | 3.13e-01 | 86.3% | 40.4% |
| 16vpA00 | 1.10.1290.10 | Mainly Alpha › Orthogonal Bundle › Conserved core of transcriptional regulatory protein vp16 › Alpha trans-inducing (Alpha-TIF) | 0.58 | 44.0 | 2.91e-01 | 80.8% | 72.0% |
| 5vjcA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.58 | 47.0 | 3.28e-01 | 91.8% | 57.3% |
| 3t9jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 45.0 | 3.68e-01 | 86.3% | 100.0% |
| 5mv9A01 | 1.25.40.530 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain | 0.58 | 41.0 | 3.18e-01 | 76.7% | 41.5% |
| 4ezbA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.57 | 44.0 | 3.82e-01 | 83.6% | 82.9% |
| 3ismC01 | 1.25.40.240 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ku, C-terminal domain | 0.57 | 43.0 | 3.48e-01 | 84.9% | 56.5% |
| 8kcaB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 45.0 | 3.42e-01 | 87.7% | 38.6% |
| 5dllA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.56 | 43.0 | 2.87e-01 | 86.3% | 37.7% |
| 1w6kA03 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.55 | 44.0 | 3.00e-01 | 90.4% | 63.5% |
| 2kkmA01 | 1.20.1440.170 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Translation machinery-associated protein 16-like | 0.54 | 38.0 | 3.31e-01 | 76.7% | 95.2% |
| 4hi8A00 | 1.25.40.20 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ankyrin repeat-containing domain | 0.53 | 38.0 | 2.92e-01 | 75.3% | 37.6% |
| 2c53A00 | 3.40.470.10 | Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain | 0.52 | 37.0 | 2.71e-01 | 75.3% | 67.1% |
| 2xvtC00 | 1.10.150.510 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family | 0.52 | 39.0 | 3.86e-01 | 80.8% | 84.8% |
| 3lpaA00 | 3.40.50.200 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Peptidase S8/S53 domain | 0.50 | 39.0 | 2.59e-01 | 87.7% | 85.0% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3895604 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.74 | 57.0 | 4.38e-01 | 82.2% | 70.0% |
| 3707987 | 109.4.1.917 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_TT21_N | 0.73 | 53.0 | 3.58e-01 | 78.1% | 36.4% |
| 3937129 | 109.4.1.921 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_IF140-IFT172 | 0.69 | 56.0 | 3.55e-01 | 89.0% | 39.7% |
| 3712352 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.69 | 49.0 | 3.54e-01 | 75.3% | 32.0% |
| 3999856 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.68 | 56.0 | 3.59e-01 | 90.4% | 39.2% |
| 4521765 | 604.29.1.1 ↗ | alpha bundles › Spectrin repeat-like › Trehalose-6-phosphate phosphatase N-terminal helical bundle › Trehalose-6-phosphate phosphatase N-terminal helical bundle › T6PP_N | 0.68 | 47.0 | 3.97e-01 | 72.6% | 71.2% |
| 3801763 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.68 | 49.0 | 3.40e-01 | 75.3% | 29.4% |
| 3368995 | 109.4.1.1525 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, DYW_deaminase | 0.68 | 50.0 | 3.29e-01 | 78.1% | 35.2% |
| 3744437 | 109.4.1.335 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SEN1_N | 0.67 | 51.0 | 3.22e-01 | 83.6% | 23.9% |
| 3584345 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.66 | 47.0 | 3.83e-01 | 74.0% | 65.9% |
| 3522803 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 48.0 | 3.46e-01 | 78.1% | 50.7% |
| 3600071 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.66 | 50.0 | 5.23e-01 | 80.8% | 92.3% |
| 4003778 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 46.0 | 3.10e-01 | 72.6% | 33.3% |
| 4989807 | 129.1.1.16 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 | 0.65 | 48.0 | 4.06e-01 | 79.5% | 99.2% |
| 3717149 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.64 | 50.0 | 3.58e-01 | 84.9% | 48.2% |
| 4984350 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.63 | 44.0 | 3.49e-01 | 72.6% | 52.0% |
| 4013890 | 109.2.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid | 0.63 | 54.0 | 3.31e-01 | 91.8% | 41.9% |
| 3668207 | 109.4.1.1258 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2 | 0.63 | 48.0 | 3.56e-01 | 82.2% | 55.8% |
| 3665251 | 109.2.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Glyco_hydro_9 | 0.63 | 53.0 | 3.25e-01 | 98.6% | 47.7% |
| 4946837 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.63 | 50.0 | 4.02e-01 | 87.7% | 62.2% |
| 3596182 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 52.0 | 3.20e-01 | 94.5% | 62.4% |
| 3997797 | 2003.1.5.73 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 | 0.62 | 48.0 | 3.58e-01 | 82.2% | 38.9% |
| 3518149 | 109.4.1.1367 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26723 | 0.62 | 49.0 | 3.62e-01 | 90.4% | 61.4% |
| 3627141 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 52.0 | 3.60e-01 | 94.5% | 58.4% |
| 3936862 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 43.0 | 3.22e-01 | 74.0% | 53.9% |
| 3385164 | 109.4.1.1261 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long | 0.60 | 45.0 | 3.07e-01 | 80.8% | 37.8% |
| 3681867 | 109.4.1.2177 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, E_motif, TPR_24 | 0.60 | 50.0 | 3.12e-01 | 95.9% | 79.1% |
| 3714699 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 47.0 | 3.56e-01 | 86.3% | 67.2% |
| 5019590 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 44.0 | 3.15e-01 | 82.2% | 61.4% |
| 3338362 | 109.4.1.1261 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2, PPR_long | 0.59 | 45.0 | 3.46e-01 | 83.6% | 61.2% |
| 3831817 | 109.4.1.1256 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 | 0.58 | 50.0 | 3.94e-01 | 98.6% | 90.0% |
| 3329960 | 109.4.1.1286 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 | 0.58 | 46.0 | 3.05e-01 | 86.3% | 36.5% |
| 3681153 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.57 | 44.0 | 3.44e-01 | 84.9% | 76.4% |
| 3464051 | 109.4.1.1295 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, TPR_24 | 0.57 | 41.0 | 3.09e-01 | 78.1% | 57.9% |
| 4020083 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.56 | 47.0 | 3.84e-01 | 94.5% | 78.6% |
| 3696425 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 45.0 | 3.52e-01 | 94.5% | 51.4% |
| 4157268 | 6102.1.1.1 ↗ | alpha arrays › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › SMC_ScpA | 0.56 | 47.0 | 3.31e-01 | 91.8% | 33.0% |
| 5068344 | 6102.1.1.1 ↗ | alpha arrays › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › SMC_ScpA | 0.56 | 45.0 | 3.70e-01 | 86.3% | 64.6% |
| 3375012 | 2004.1.1.364 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C | 0.56 | 48.0 | 2.93e-01 | 97.3% | 64.1% |
| 3661674 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 40.0 | 3.35e-01 | 79.5% | 71.4% |
| 3695837 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 45.0 | 3.61e-01 | 95.9% | 72.1% |
| 3810859 | 170.1.1.15 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C › Retrotran_gag_2 | 0.54 | 41.0 | 3.73e-01 | 79.5% | 83.2% |
| 3635498 | 2004.1.1.364 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C | 0.54 | 44.0 | 2.66e-01 | 90.4% | 40.0% |
| 3926415 | 170.1.1.15 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C › Retrotran_gag_2 | 0.53 | 40.0 | 3.87e-01 | 80.8% | 90.6% |
| 3725437 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 39.0 | 3.59e-01 | 86.3% | 96.4% |
| 3728294 | 170.1.1.0 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C | 0.53 | 39.0 | 3.71e-01 | 84.9% | 95.8% |
| 3170562 | 2484.5.1.5 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › TYA | 0.51 | 40.0 | 3.77e-01 | 87.7% | 98.9% |
| 4049000 | 170.1.1.17 ↗ | alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C › TYA | 0.51 | 40.0 | 3.79e-01 | 90.4% | 98.9% |
| 4000306 | 304.9.1.83 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1, RBM39linker | 0.51 | 44.0 | 2.78e-01 | 93.2% | 23.9% |
| 4627550 | 4954.1.1.1 ↗ | a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 | 0.51 | 41.0 | 2.82e-01 | 90.4% | 78.9% |
D4
medium
residues 581-636
D5
medium
residues 637-693
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3hkvA00 | 3.90.228.10 | Alpha Beta › Alpha-Beta Complex › Phosphoenolpyruvate Carboxykinase; domain 3 › | 0.77 | 66.0 | 4.56e-01 | 96.5% | 99.5% |
| 3u1wA01 | 3.10.450.360 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.74 | 61.0 | 4.29e-01 | 100.0% | 29.0% |
| 4hbrA00 | 3.10.450.360 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.72 | 60.0 | 4.55e-01 | 100.0% | 38.6% |
| 3iwcB00 | 3.30.360.110 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › S-adenosylmethionine decarboxylase domain | 0.63 | 40.0 | 3.96e-01 | 77.2% | 59.0% |
| 1kutA02 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.63 | 50.0 | 3.98e-01 | 94.7% | 88.0% |
| 3c8mA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.60 | 43.0 | 3.22e-01 | 77.2% | 65.6% |
| 3n8bA00 | 3.10.450.700 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.60 | 40.0 | 3.69e-01 | 94.7% | 53.3% |
| 4gakA00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.60 | 46.0 | 3.05e-01 | 86.0% | 35.2% |
| 2d42A02 | 3.10.450.380 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.60 | 40.0 | 3.85e-01 | 86.0% | 60.0% |
| 1jnrB02 | 6.20.260.10 | Special › Other non-globular › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Adenylylsulphate reductase, beta subunit, C-terminal domain | 0.59 | 38.0 | 3.39e-01 | 100.0% | 42.2% |
| 5wpjA02 | 3.30.70.420 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain | 0.59 | 44.0 | 3.72e-01 | 86.0% | 49.1% |
| 1wznA02 | 2.20.25.110 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases | 0.59 | 40.0 | 4.07e-01 | 96.5% | 73.2% |
| 4b6uA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.58 | 49.0 | 3.41e-01 | 98.2% | 40.1% |
| 2lmeA00 | 3.30.1300.30 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like | 0.57 | 38.0 | 3.15e-01 | 100.0% | 37.1% |
| 3bxoA02 | 2.20.130.10 | Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › CAC2371-like domains | 0.56 | 39.0 | 3.90e-01 | 98.2% | 69.5% |
| 3ayjA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.55 | 40.0 | 2.51e-01 | 78.9% | 78.9% |
| 1xmxA02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.55 | 40.0 | 3.03e-01 | 78.9% | 85.9% |
| 4ks9B02 | 3.40.630.150 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Malonyl-CoA decarboxylase, catalytic domain | 0.55 | 44.0 | 2.93e-01 | 94.7% | 25.3% |
| 3d7jA00 | 3.30.479.10 | Alpha Beta › 2-Layer Sandwich › Tetrahydropterin Synthase; Chain A › 6-pyruvoyl tetrahydropterin synthase/QueD | 0.55 | 46.0 | 3.58e-01 | 98.2% | 91.0% |
| 2aj4B01 | 3.30.230.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › | 0.55 | 44.0 | 3.01e-01 | 96.5% | 64.9% |
| 1hw7A01 | 3.55.30.10 | Alpha Beta › 3-Layer(bab) Sandwich › Hsp33 domain › Hsp33 domain | 0.54 | 38.0 | 2.80e-01 | 75.4% | 42.8% |
| 1vq0A01 | 3.55.30.10 | Alpha Beta › 3-Layer(bab) Sandwich › Hsp33 domain › Hsp33 domain | 0.54 | 43.0 | 2.92e-01 | 91.2% | 40.8% |
| 3cinA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.53 | 37.0 | 3.13e-01 | 75.4% | 81.7% |
| 6k96B02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.53 | 37.0 | 3.15e-01 | 73.7% | 76.3% |
| 2cc6A00 | 3.30.1660.10 | Alpha Beta › 2-Layer Sandwich › Dodecin subunit-like › Flavin-binding protein dodecin | 0.52 | 37.0 | 3.63e-01 | 78.9% | 73.4% |
| 1gr0A02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.52 | 36.0 | 3.25e-01 | 75.4% | 75.0% |
| 2r76A00 | 3.30.160.150 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain | 0.51 | 37.0 | 2.92e-01 | 78.9% | 86.4% |
| 7ctpA01 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.50 | 41.0 | 3.20e-01 | 96.5% | 42.5% |
| 1tkkA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.50 | 38.0 | 3.20e-01 | 98.2% | 44.3% |
| 1ryp200 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.50 | 38.0 | 2.56e-01 | 84.2% | 34.8% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3324343 | 237.1.1.1 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › PARP | 0.79 | 64.0 | 4.41e-01 | 89.5% | 100.0% |
| 3862949 | 237.1.1.1 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation › PARP | 0.78 | 68.0 | 4.67e-01 | 100.0% | 97.0% |
| 3597511 | 237.1.1.0 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation | 0.77 | 63.0 | 4.35e-01 | 93.0% | 99.5% |
| 3711853 | 237.1.1.0 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation | 0.76 | 65.0 | 4.55e-01 | 100.0% | 95.3% |
| 3798872 | 237.1.1.0 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation | 0.75 | 67.0 | 4.42e-01 | 100.0% | 92.6% |
| 3353724 | 237.1.1.0 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation | 0.74 | 63.0 | 4.39e-01 | 96.5% | 98.9% |
| 3508384 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.74 | 64.0 | 5.02e-01 | 96.5% | 56.7% |
| 3814112 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.74 | 63.0 | 4.35e-01 | 98.2% | 99.5% |
| 3577125 | 809.2.1.4 ↗ | a+b two layers › BLIP-like › BT0923-like › BT0923-like › Herpes_UL52 | 0.73 | 62.0 | 5.01e-01 | 94.7% | 50.9% |
| 3997265 | 237.1.1.0 ↗ | a+b complex topology › ADP-ribosylation › ADP-ribosylation › ADP-ribosylation | 0.73 | 61.0 | 4.21e-01 | 96.5% | 98.1% |
| 3519076 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.72 | 61.0 | 4.56e-01 | 96.5% | 62.8% |
| 4255814 | 3781.1.1.0 ↗ | a+b two layers › Ribosomal protein L11/L12e N-terminal domain-like › Ribosomal protein L11/L12e N-terminal domain › Ribosomal protein L11/L12e N-terminal domain | 0.67 | 58.0 | 5.42e-01 | 94.7% | 100.0% |
| 3585192 | 387.1.5.0 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › Scorpion toxin-like | 0.67 | 52.0 | 5.49e-01 | 89.5% | 100.0% |
| 3674091 | 9.23.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Hypothetical protein BT_0869 › Hypothetical protein BT_0869 › PAP_fibrillin | 0.63 | 53.0 | 3.63e-01 | 94.7% | 26.6% |
| 3954005 | 256.1.1.0 ↗ | a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like | 0.62 | 41.0 | 4.12e-01 | 78.9% | 65.0% |
| 3402405 | 4.1.1.326 ↗ | beta barrels › SH3 › SH3 › SH3 › Chitin_bind_4 | 0.62 | 40.0 | 3.92e-01 | 98.2% | 60.3% |
| 3265716 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.61 | 51.0 | 4.47e-01 | 96.5% | 67.8% |
| 3408795 | 12.1.1.60 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Chitin_bind_4 | 0.61 | 39.0 | 3.84e-01 | 96.5% | 60.7% |
| 4957051 | 243.6.1.0 ↗ | a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain | 0.60 | 50.0 | 3.67e-01 | 96.5% | 49.7% |
| 4276539 | 4194.1.1.2 ↗ | a+b duplicates or obligate multimers › Prenyltransferase-like › Prenyltransferase-like › Prenyltransferase-like › Trp_DMAT | 0.59 | 48.0 | 2.97e-01 | 100.0% | 18.6% |
| 3414586 | 11.1.1.824 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Chitin_bind_4 | 0.59 | 38.0 | 3.32e-01 | 98.2% | 40.9% |
| 5000908 | 304.6.1.1 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C | 0.58 | 49.0 | 3.22e-01 | 98.2% | 57.0% |
| 3591987 | 2003.1.5.24 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Met_10 | 0.58 | 49.0 | 3.08e-01 | 100.0% | 89.0% |
| 4558948 | 256.1.1.0 ↗ | a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like | 0.57 | 38.0 | 3.83e-01 | 77.2% | 66.7% |
| 4558605 | 220.5.1.1 ↗ | beta barrels › PH domain-like › NucS N-terminal domain › NucS N-terminal domain › NucS_N | 0.57 | 50.0 | 3.92e-01 | 98.2% | 62.5% |
| 4030444 | 330.1.1.0 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like | 0.56 | 47.0 | 3.85e-01 | 94.7% | 52.7% |
| 3961113 | 206.1.1.12 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › SelO | 0.55 | 47.0 | 3.23e-01 | 96.5% | 71.4% |
| 3474976 | 331.9.1.0 ↗ | a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain | 0.55 | 40.0 | 3.09e-01 | 96.5% | 34.6% |
| 3205676 | 4020.1.1.0 ↗ | a+b two layers › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes | 0.54 | 44.0 | 3.66e-01 | 96.5% | 93.0% |
| 4007831 | 304.6.1.1 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C | 0.54 | 44.0 | 3.01e-01 | 98.2% | 58.8% |
| 3277250 | 2485.1.1.107 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › PF30536 | 0.53 | 40.0 | 3.42e-01 | 80.7% | 66.3% |
| 4030677 | 1116.1.1.0 ↗ | a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain | 0.53 | 39.0 | 2.90e-01 | 100.0% | 29.3% |
| 2589713 | 283.2.1.1 ↗ | a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GPW_gp25 | 0.53 | 39.0 | 3.12e-01 | 86.0% | 37.6% |
| 5009342 | 298.1.1.3 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Inos-1-P_synth | 0.52 | 38.0 | 3.23e-01 | 80.7% | 72.4% |
| 3165355 | 206.1.1.17 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Kdo | 0.52 | 44.0 | 2.93e-01 | 94.7% | 52.5% |
| 5042918 | 3153.1.1.0 ↗ | a+b two layers › PipX › PipX › PipX | 0.51 | 45.0 | 3.72e-01 | 100.0% | 56.0% |
| 4950024 | 298.1.1.3 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Inos-1-P_synth | 0.50 | 40.0 | 3.33e-01 | 89.5% | 53.6% |
| 4971967 | 298.1.1.3 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Inos-1-P_synth | 0.50 | 39.0 | 3.35e-01 | 91.2% | 54.3% |
D6
medium
residues 694-777