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FAD-dependent_thymidylate_synthase

Euk-Vir

Heterosigma_akashiwo_virus_01

FAD-dependent_thymidylate_synthase__YP_009507550__Heterosigma_akashiwo_virus_01__97195

Identity

Accession:
YP_009507550 ↗
Protein ID:
FAD-dependent_thymidylate_synthase
Kingdom:
euk

Quality

84.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-99_179-233
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02511.21 best Thy1 87.6 1.30e-24 57.7% 45.0%
PF02511.21 Thy1 46.5 5.00e-12 31.5% 23.6%
D2 high residues 114-173
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kq4A00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.87 65.0 4.35e-01 100.0% 23.2%
4p5aC00 3.30.1360.170 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.84 74.0 4.90e-01 100.0% 26.0%
3k4iC02 1.20.5.3070 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.83 51.0 6.22e-01 100.0% 100.0%
4lctB00 1.25.40.570 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.74 58.0 3.56e-01 85.0% 30.2%
3v9rB00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.70 63.0 5.90e-01 100.0% 81.9%
1s2gB00 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 41.0 2.94e-01 86.7% 83.8%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5069296 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.87 53.0 3.35e-01 96.7% 14.5%
1716752 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.84 74.0 4.91e-01 100.0% 25.7%
4930198 605.1.1.2 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim 0.80 52.0 5.22e-01 98.3% 66.7%
5015585 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.79 59.0 4.70e-01 93.3% 41.6%
4987757 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.79 59.0 4.91e-01 95.0% 46.2%
5013251 3291.1.1.195 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › H-kinase_dim 0.76 53.0 3.99e-01 76.7% 30.8%
3166522 109.4.1.152 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RPN7 0.76 59.0 3.66e-01 85.0% 33.0%
4667663 148.1.1.96 alpha arrays › Histone-like › Histone-related › Histone › Bromo_TP_like 0.72 65.0 5.62e-01 100.0% 65.6%
4857394 5054.1.1.6 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH 0.71 63.0 4.88e-01 96.7% 48.4%
3565991 109.4.1.1415 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BCD_RFX 0.66 54.0 3.38e-01 88.3% 62.6%
3373588 3887.2.1.1 a+b two layers › Yeast killer toxin-like › Antifungal protein ginkbilobin-2 › Antifungal protein ginkbilobin-2 › Stress-antifung 0.64 52.0 4.19e-01 91.7% 80.0%
D3 medium residues 241-276
PDB