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FEN1-like_nuclease

Euk-Vir

Eastern_grey_kangaroopox_virus

FEN1-like_nuclease__YP_010085352__Eastern_grey_kangaroopox_virus__2042482

Identity

Accession:
YP_010085352 ↗
Protein ID:
FEN1-like_nuclease
Kingdom:
euk

Quality

83.2 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Macropopoxvirus› Eastern_grey_kangaroopox_virus

TaxID: 2042482

Cluster

View cluster (33 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 240-326
PDB
Domain cluster: rep: Hypothetical_protein_YMTVg54R__NP_938309__Yaba_monkey_tumor_virus__38804__D253-335
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04599.18 best Pox_G5 66.7 2.80e-18 100.0% 20.2%
D2 high residues 337-429
PDB
D3 medium residues 1-37_64-74_160-239
PDB
Domain cluster: rep: virion_core_protein__YP_784266__Nile_crocodilepox_virus__1285600__D1-41_162-217
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF04599.18 best Pox_G5 107.5 1.20e-30 70.3% 20.0%
PF04599.18 Pox_G5 28.8 9.10e-07 32.8% 8.9%
D4 medium residues 38-63_75-159
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04599.18 best Pox_G5 83.6 2.20e-23 100.0% 28.5%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3kr9A02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 39.0 5.38e-01 80.2% 100.0%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.71 52.0 5.84e-01 87.4% 93.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 50.0 5.49e-01 88.3% 88.0%
3emlA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.70 49.0 3.57e-01 72.1% 56.9%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.69 39.0 4.39e-01 82.9% 71.8%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.68 57.0 3.94e-01 87.4% 86.2%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 47.0 4.97e-01 88.3% 82.2%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.65 39.0 4.40e-01 79.3% 78.2%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.64 40.0 4.45e-01 90.1% 81.2%
7xxiA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 47.0 3.47e-01 80.2% 88.3%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 44.0 4.58e-01 86.5% 78.3%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 43.0 4.61e-01 84.7% 85.4%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.61 43.0 4.33e-01 84.7% 71.9%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.59 53.0 3.63e-01 100.0% 92.6%
2v0pA00 1.25.40.540 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family 0.59 48.0 3.86e-01 87.4% 66.1%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 48.0 4.67e-01 87.4% 80.0%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.58 46.0 4.14e-01 83.8% 96.7%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.58 46.0 4.11e-01 84.7% 65.4%
2q5zB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.57 40.0 4.26e-01 84.7% 84.0%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.53 41.0 3.84e-01 82.9% 65.7%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 43.0 4.22e-01 87.4% 95.8%
4b7yD00 3.30.40.10 Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) 0.52 39.0 4.16e-01 86.5% 88.7%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 41.0 3.95e-01 87.4% 98.5%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3588519 101.1.2.49 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.70 49.0 4.18e-01 83.8% 47.9%
3409618 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.69 51.0 3.63e-01 76.6% 55.2%
4180833 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.68 49.0 3.73e-01 75.7% 73.5%
3676480 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.68 48.0 5.30e-01 87.4% 91.1%
4015806 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.67 44.0 3.35e-01 83.8% 30.8%
3340833 5086.1.1.109 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Chloroplast_duf 0.67 46.0 5.10e-01 85.6% 87.8%
3462100 604.1.1.102 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF8324 0.66 53.0 5.15e-01 87.4% 77.5%
3741709 261.1.1.1 ↗ a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT 0.66 45.0 2.65e-01 70.3% 19.0%
3512504 192.5.1.0 ↗ alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.65 53.0 4.99e-01 87.4% 96.3%
3978007 3755.3.1.15 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › MscS_porin 0.64 50.0 4.76e-01 83.8% 69.2%
3690673 5050.1.1.1 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.64 43.0 3.65e-01 79.3% 42.9%
3722750 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.64 52.0 3.67e-01 85.6% 38.4%
3212841 5001.1.1.35 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srsx 0.64 50.0 3.68e-01 82.9% 82.1%
3914846 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.63 48.0 4.46e-01 79.3% 65.7%
None — 0.63 49.0 3.65e-01 82.9% 82.1%
4018370 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.61 50.0 4.76e-01 87.4% 80.8%
3783206 630.1.1.2 ↗ a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › PF29521 0.60 47.0 4.44e-01 82.0% 75.4%
5050107 159.1.1.1 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.59 39.0 4.16e-01 83.8% 77.9%
4336172 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.59 49.0 3.54e-01 91.9% 57.9%
4605223 375.1.9.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase 0.57 38.0 4.18e-01 89.2% 83.3%
5047572 5001.1.1.0 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.57 45.0 3.54e-01 82.9% 82.8%
2968353 3758.2.1.2 ↗ alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB 0.55 49.0 3.79e-01 100.0% 100.0%
5009681 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.54 45.0 4.18e-01 92.8% 70.0%
3741656 630.1.1.2 ↗ a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › PF29521 0.54 44.0 4.15e-01 87.4% 100.0%
3449605 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.52 40.0 4.11e-01 82.0% 83.6%
4951260 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.50 39.0 3.62e-01 82.0% 76.4%