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FO818745.1__CDN90869.1__EC725RCS47_p0117__00129
Bact-VirFO818745.1__CDN90869.1__EC725RCS47_p0117__00129
Identity
- Accession:
- FO818745 ↗
- Kingdom:
- phage
Quality
93.5
mean pLDDT
Taxonomy
TaxID: 1590550
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-129
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04976.18 best | DmsC | 80.9 | 1.50e-22 | 100.0% | 46.2% |
CATH (55)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.78 | 62.0 | 6.57e-01 | 100.0% | 93.8% |
| 2vpzC00 | 1.20.1630.10 | Mainly Alpha › Up-down Bundle › Formate dehydrogenase/DMSO reductase fold › Formate dehydrogenase/DMSO reductase domain | 0.77 | 70.0 | 5.52e-01 | 100.0% | 49.2% |
| 1kqfC00 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.76 | 70.0 | 5.83e-01 | 100.0% | 88.0% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.72 | 60.0 | 5.24e-01 | 100.0% | 60.9% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.71 | 60.0 | 6.21e-01 | 100.0% | 96.6% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.70 | 63.0 | 6.19e-01 | 100.0% | 89.1% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.69 | 56.0 | 4.60e-01 | 85.7% | 88.3% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.69 | 59.0 | 5.39e-01 | 100.0% | 70.5% |
| 1st6A02 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.68 | 54.0 | 4.44e-01 | 100.0% | 46.2% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.68 | 55.0 | 5.59e-01 | 100.0% | 88.0% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 60.0 | 6.02e-01 | 100.0% | 96.1% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.67 | 58.0 | 5.74e-01 | 100.0% | 90.2% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 53.0 | 5.49e-01 | 97.6% | 90.0% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.67 | 55.0 | 5.55e-01 | 100.0% | 89.4% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.66 | 49.0 | 4.50e-01 | 77.0% | 82.6% |
| 4c91A03 | 1.20.58.2150 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 48.0 | 4.31e-01 | 81.0% | 54.2% |
| 1q16C01 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.65 | 59.0 | 4.98e-01 | 100.0% | 72.9% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.65 | 47.0 | 5.10e-01 | 81.0% | 91.2% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.64 | 58.0 | 5.47e-01 | 100.0% | 84.3% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.64 | 51.0 | 5.31e-01 | 97.6% | 94.7% |
| 4rm7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 47.0 | 4.57e-01 | 77.0% | 71.2% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.63 | 58.0 | 4.26e-01 | 100.0% | 84.6% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.63 | 57.0 | 4.87e-01 | 98.4% | 98.0% |
| 8hk0C01 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 47.0 | 4.45e-01 | 77.8% | 68.7% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 56.0 | 5.67e-01 | 100.0% | 100.0% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.63 | 57.0 | 4.96e-01 | 100.0% | 76.0% |
| 3i1aA03 | 1.20.58.840 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 44.0 | 4.54e-01 | 77.0% | 78.4% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 44.0 | 4.23e-01 | 79.4% | 63.6% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 48.0 | 4.91e-01 | 81.0% | 94.3% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 43.0 | 4.67e-01 | 77.0% | 84.1% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 55.0 | 5.46e-01 | 97.6% | 100.0% |
| 5u1aL00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 52.0 | 4.75e-01 | 90.5% | 98.2% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 44.0 | 3.72e-01 | 76.2% | 75.2% |
| 8bb6A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.60 | 56.0 | 3.73e-01 | 100.0% | 29.2% |
| 7cj3A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 53.0 | 4.28e-01 | 100.0% | 98.8% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 42.0 | 3.98e-01 | 81.7% | 60.4% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.59 | 51.0 | 5.26e-01 | 96.8% | 100.0% |
| 3m71A00 | 1.50.10.150 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Voltage-dependent anion channel | 0.58 | 51.0 | 3.85e-01 | 96.0% | 82.8% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 45.0 | 4.07e-01 | 82.5% | 75.1% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.57 | 49.0 | 4.28e-01 | 100.0% | 61.3% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 46.0 | 3.84e-01 | 85.7% | 83.8% |
| 4cbeA00 | 1.20.120.1640 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 51.0 | 4.36e-01 | 100.0% | 68.9% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 45.0 | 4.61e-01 | 84.1% | 93.3% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 42.0 | 3.75e-01 | 77.0% | 89.0% |
| 2uuiA00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.57 | 42.0 | 3.93e-01 | 77.0% | 63.2% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 39.0 | 3.86e-01 | 70.6% | 74.2% |
| 3kkdA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 43.0 | 3.79e-01 | 83.3% | 72.7% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 43.0 | 3.37e-01 | 82.5% | 85.5% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.55 | 42.0 | 3.35e-01 | 79.4% | 83.7% |
| 1w9cA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.55 | 43.0 | 3.22e-01 | 83.3% | 38.0% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 43.0 | 4.29e-01 | 96.8% | 80.8% |
| 2q7rB00 | 1.20.120.550 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain | 0.54 | 39.0 | 3.80e-01 | 77.0% | 67.3% |
| 1jr3C02 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.53 | 43.0 | 4.45e-01 | 88.1% | 93.4% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 46.0 | 4.40e-01 | 95.2% | 93.8% |
| 2yinA03 | 1.20.58.740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C | 0.52 | 45.0 | 4.54e-01 | 94.4% | 100.0% |
ECOD (75)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3981701 | 5069.1.1.28 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DmsC | 1.00 | 97.0 | 8.62e-01 | 100.0% | 75.8% |
| 3981425 | 5069.1.1.28 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DmsC | 0.92 | 89.0 | 7.94e-01 | 100.0% | 76.4% |
| 3982145 | 5069.1.1.28 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DmsC | 0.91 | 88.0 | 7.67e-01 | 100.0% | 73.7% |
| 3978470 | 5069.1.1.28 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DmsC | 0.89 | 79.0 | 7.38e-01 | 100.0% | 77.3% |
| 4076972 | 5069.1.1.28 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DmsC | 0.88 | 84.0 | 7.22e-01 | 100.0% | 76.8% |
| 5009665 | 5069.1.1.26 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › NrfD | 0.88 | 83.0 | 7.30e-01 | 100.0% | 73.7% |
| 3929785 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.85 | 80.0 | 6.49e-01 | 100.0% | 67.3% |
| 3981781 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.84 | 79.0 | 6.26e-01 | 100.0% | 57.9% |
| 3195245 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.81 | 77.0 | 6.55e-01 | 100.0% | 66.8% |
| 184932 | 5069.1.1.8 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › NrfD_2 | 0.77 | 70.0 | 6.77e-01 | 100.0% | 87.9% |
| 4016004 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.77 | 71.0 | 6.26e-01 | 100.0% | 70.0% |
| 3980115 | 5069.1.1.15 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm | 0.76 | 71.0 | 6.83e-01 | 100.0% | 96.5% |
| 4022969 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.76 | 68.0 | 5.91e-01 | 100.0% | 65.4% |
| 3212004 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.75 | 70.0 | 6.25e-01 | 100.0% | 77.6% |
| 3217635 | 3684.1.1.30 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF29678 | 0.75 | 67.0 | 6.00e-01 | 100.0% | 70.6% |
| 4946349 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.73 | 54.0 | 5.21e-01 | 76.2% | 87.9% |
| 3253939 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.72 | 63.0 | 6.46e-01 | 100.0% | 99.2% |
| 3965345 | 5069.1.1.15 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm | 0.72 | 67.0 | 6.44e-01 | 100.0% | 93.6% |
| 3203851 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 66.0 | 6.00e-01 | 100.0% | 86.7% |
| 3419853 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.71 | 62.0 | 5.95e-01 | 100.0% | 81.4% |
| 3823532 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.71 | 62.0 | 5.92e-01 | 100.0% | 81.4% |
| 3459287 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.71 | 65.0 | 5.95e-01 | 100.0% | 87.3% |
| 3217606 | 192.29.1.172 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 | 0.70 | 63.0 | 5.55e-01 | 100.0% | 67.8% |
| 3920506 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.70 | 63.0 | 5.91e-01 | 99.2% | 96.1% |
| 3391109 | 3684.1.1.21 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › TMEM138 | 0.70 | 64.0 | 6.21e-01 | 100.0% | 100.0% |
| 3605561 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 64.0 | 5.84e-01 | 100.0% | 88.5% |
| 4631215 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.69 | 61.0 | 6.26e-01 | 95.2% | 99.2% |
| 3948656 | 601.4.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT | 0.69 | 59.0 | 5.56e-01 | 100.0% | 75.5% |
| 3536637 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.69 | 53.0 | 5.07e-01 | 79.4% | 71.3% |
| 3171851 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.69 | 63.0 | 5.84e-01 | 100.0% | 78.8% |
| 4587229 | 5000.4.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain | 0.69 | 63.0 | 5.29e-01 | 100.0% | 96.7% |
| 3840081 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.68 | 62.0 | 5.94e-01 | 100.0% | 86.7% |
| 3656892 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.68 | 47.0 | 4.70e-01 | 77.0% | 68.5% |
| 3724867 | 192.15.1.1 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28 | 0.68 | 44.0 | 4.91e-01 | 91.3% | 82.0% |
| 3229987 | 5001.1.1.25 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sru | 0.68 | 62.0 | 4.63e-01 | 100.0% | 80.0% |
| 3752923 | 601.4.1.42 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TMEM138 | 0.68 | 62.0 | 5.79e-01 | 100.0% | 87.1% |
| 3218065 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.68 | 59.0 | 5.72e-01 | 100.0% | 85.0% |
| 3551795 | 192.15.1.1 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28 | 0.67 | 46.0 | 4.97e-01 | 81.0% | 80.9% |
| 3466941 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.67 | 61.0 | 5.09e-01 | 100.0% | 81.2% |
| 3184336 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 50.0 | 4.65e-01 | 77.8% | 67.1% |
| 3952765 | 192.29.1.179 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF26307 | 0.67 | 60.0 | 5.76e-01 | 100.0% | 95.9% |
| 4223050 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.67 | 62.0 | 5.50e-01 | 100.0% | 80.3% |
| 3247154 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 55.0 | 5.06e-01 | 100.0% | 69.1% |
| 3239357 | 192.29.1.51 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM138 | 0.66 | 61.0 | 5.87e-01 | 100.0% | 92.9% |
| 3583915 | 192.29.1.51 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM138 | 0.66 | 60.0 | 5.85e-01 | 100.0% | 98.6% |
| 3547281 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.66 | 50.0 | 3.96e-01 | 82.5% | 40.0% |
| 3579350 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.66 | 59.0 | 4.78e-01 | 100.0% | 82.0% |
| 3212811 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.65 | 58.0 | 5.83e-01 | 96.8% | 95.4% |
| 3281928 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.65 | 57.0 | 5.44e-01 | 100.0% | 80.5% |
| 4567743 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.65 | 59.0 | 5.21e-01 | 100.0% | 69.4% |
| 3242617 | 5001.1.1.33 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srh | 0.65 | 58.0 | 4.36e-01 | 100.0% | 80.6% |
| 4098111 | 601.25.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical | 0.65 | 59.0 | 5.41e-01 | 100.0% | 84.2% |
| 5078219 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.65 | 56.0 | 4.96e-01 | 92.1% | 85.1% |
| 3907213 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 48.0 | 5.36e-01 | 81.7% | 99.0% |
| 3213348 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.64 | 49.0 | 4.82e-01 | 79.4% | 77.0% |
| 3273336 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 58.0 | 4.68e-01 | 100.0% | 90.2% |
| 3250233 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 58.0 | 5.06e-01 | 98.4% | 66.5% |
| 3739436 | 601.4.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B | 0.64 | 56.0 | 5.49e-01 | 100.0% | 87.4% |
| 3178113 | 604.5.1.68 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TMEM33_Pom33 | 0.63 | 53.0 | 4.73e-01 | 99.2% | 63.9% |
| 3619883 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.63 | 48.0 | 4.62e-01 | 79.4% | 75.0% |
| 3433667 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.60 | 44.0 | 4.22e-01 | 77.8% | 72.0% |
| 3236786 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.59 | 45.0 | 4.36e-01 | 81.7% | 70.7% |
| 3576407 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.59 | 45.0 | 4.68e-01 | 79.4% | 97.4% |
| 3255633 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 53.0 | 4.42e-01 | 100.0% | 57.7% |
| 3227690 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.59 | 53.0 | 4.27e-01 | 100.0% | 52.3% |
| 3406894 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.59 | 55.0 | 4.66e-01 | 100.0% | 73.8% |
| 3234830 | 5001.1.1.66 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg | 0.58 | 53.0 | 3.99e-01 | 100.0% | 53.5% |
| 3366153 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.57 | 45.0 | 4.10e-01 | 84.1% | 94.7% |
| 5053834 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.56 | 52.0 | 4.67e-01 | 100.0% | 74.1% |
| 5036521 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.56 | 50.0 | 4.70e-01 | 100.0% | 81.7% |
| 3613774 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 49.0 | 4.68e-01 | 96.8% | 98.0% |
| 3729610 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.55 | 37.0 | 3.63e-01 | 73.8% | 62.1% |
| 3246395 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.55 | 47.0 | 3.99e-01 | 91.3% | 84.9% |
| 5045646 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 49.0 | 4.70e-01 | 100.0% | 97.9% |
| 3263522 | 5050.1.1.11 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › UNC-93 | 0.54 | 50.0 | 4.21e-01 | 100.0% | 61.5% |
D2
high
residues 136-252
Domain cluster:
representative
CATH (55)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1nzeA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.84 | 71.0 | 7.27e-01 | 96.6% | 93.8% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.82 | 70.0 | 7.17e-01 | 100.0% | 93.8% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.81 | 73.0 | 6.82e-01 | 100.0% | 79.7% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.81 | 74.0 | 6.40e-01 | 100.0% | 73.6% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.79 | 73.0 | 6.43e-01 | 100.0% | 71.4% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.79 | 71.0 | 5.73e-01 | 98.3% | 61.8% |
| 2p0nA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.78 | 70.0 | 6.27e-01 | 97.4% | 80.7% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.78 | 71.0 | 6.79e-01 | 98.3% | 86.5% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.77 | 71.0 | 6.71e-01 | 100.0% | 87.6% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.77 | 53.0 | 5.40e-01 | 73.5% | 72.8% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.76 | 70.0 | 6.33e-01 | 100.0% | 81.9% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.76 | 66.0 | 6.37e-01 | 98.3% | 83.5% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.76 | 65.0 | 6.31e-01 | 100.0% | 83.2% |
| 2p61A00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.76 | 65.0 | 6.62e-01 | 97.4% | 94.7% |
| 3ieeA02 | 1.20.58.820 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 | 0.76 | 62.0 | 6.59e-01 | 95.7% | 100.0% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.76 | 62.0 | 6.25e-01 | 92.3% | 86.3% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 55.0 | 5.46e-01 | 76.1% | 73.8% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.74 | 57.0 | 5.07e-01 | 79.5% | 82.6% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 65.0 | 6.44e-01 | 97.4% | 92.6% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.73 | 66.0 | 6.15e-01 | 100.0% | 85.6% |
| 2hz8A00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.73 | 64.0 | 6.48e-01 | 100.0% | 98.3% |
| 4jvsA01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.73 | 61.0 | 6.02e-01 | 90.6% | 88.9% |
| 3e0sA00 | 1.40.20.10 | Mainly Alpha › Alpha solenoid › CHAD domain › CHAD domain | 0.73 | 66.0 | 4.90e-01 | 100.0% | 48.0% |
| 1a7vA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.72 | 64.0 | 6.32e-01 | 97.4% | 96.0% |
| 4yjwA00 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.70 | 63.0 | 5.80e-01 | 100.0% | 86.9% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.70 | 53.0 | 5.38e-01 | 81.2% | 91.5% |
| 1s05A00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.70 | 62.0 | 6.02e-01 | 97.4% | 95.3% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.69 | 52.0 | 5.74e-01 | 79.5% | 100.0% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 52.0 | 5.63e-01 | 79.5% | 96.9% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.69 | 44.0 | 4.43e-01 | 77.8% | 62.9% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.69 | 49.0 | 4.20e-01 | 72.6% | 80.6% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.68 | 47.0 | 4.02e-01 | 70.9% | 55.3% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.68 | 62.0 | 5.10e-01 | 100.0% | 96.6% |
| 1xwjA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 59.0 | 5.76e-01 | 94.0% | 90.8% |
| 7q37A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.68 | 62.0 | 5.08e-01 | 100.0% | 82.7% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.66 | 48.0 | 4.21e-01 | 76.1% | 60.8% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.64 | 48.0 | 4.94e-01 | 78.6% | 100.0% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 48.0 | 5.10e-01 | 79.5% | 99.0% |
| 1sxjC03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.63 | 46.0 | 5.00e-01 | 94.0% | 93.7% |
| 3vkgB06 | 1.20.920.20 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.63 | 48.0 | 3.73e-01 | 80.3% | 71.4% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 56.0 | 4.79e-01 | 100.0% | 83.9% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 58.0 | 5.17e-01 | 100.0% | 98.7% |
| 2r9rH02 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.62 | 55.0 | 5.09e-01 | 100.0% | 92.1% |
| 3m71A00 | 1.50.10.150 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Voltage-dependent anion channel | 0.61 | 50.0 | 3.65e-01 | 87.2% | 83.4% |
| 4fzsA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 46.0 | 3.81e-01 | 78.6% | 90.9% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.60 | 51.0 | 4.66e-01 | 96.6% | 69.5% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 45.0 | 4.55e-01 | 80.3% | 100.0% |
| 2pmsC00 | 6.10.140.920 | Special › Helix non-globular › Helix Hairpins › | 0.57 | 48.0 | 5.04e-01 | 92.3% | 98.2% |
| 2w53B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 48.0 | 4.27e-01 | 96.6% | 70.5% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.55 | 47.0 | 4.33e-01 | 94.9% | 85.9% |
| 7fhyB01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.54 | 47.0 | 3.56e-01 | 95.7% | 96.9% |
| 1ek9A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.52 | 47.0 | 3.20e-01 | 100.0% | 91.1% |
| 2oyoA02 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.52 | 36.0 | 3.60e-01 | 72.6% | 88.8% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 43.0 | 4.04e-01 | 95.7% | 82.4% |
| 2icwG01 | 1.20.120.390 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hla class ii histocompatibility antigen, dr alpha chain. Chain D, domain 1 | 0.51 | 45.0 | 4.48e-01 | 100.0% | 96.8% |
ECOD (73)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4034204 | 5069.1.1.5 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_II | 0.84 | 78.0 | 6.67e-01 | 97.4% | 67.4% |
| 4118682 | 601.18.1.22 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › FTR1 | 0.84 | 59.0 | 6.86e-01 | 96.6% | 100.0% |
| 4048397 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.83 | 61.0 | 6.59e-01 | 94.9% | 89.0% |
| 3454282 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.82 | 76.0 | 6.60e-01 | 100.0% | 94.3% |
| 3994851 | 601.1.2.63 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R | 0.82 | 73.0 | 6.62e-01 | 100.0% | 73.3% |
| 3488339 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.82 | 57.0 | 6.61e-01 | 73.5% | 98.8% |
| 4942306 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.81 | 70.0 | 7.27e-01 | 93.2% | 98.2% |
| 4963908 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.81 | 75.0 | 6.98e-01 | 100.0% | 93.7% |
| 4441744 | 601.4.1.78 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DAHL | 0.81 | 75.0 | 7.28e-01 | 100.0% | 94.6% |
| 3251836 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.81 | 73.0 | 7.04e-01 | 97.4% | 93.8% |
| 4102845 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.81 | 71.0 | 7.10e-01 | 100.0% | 92.5% |
| 5025071 | 5069.1.1.3 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I | 0.81 | 73.0 | 6.35e-01 | 98.3% | 81.1% |
| 3730903 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.81 | 73.0 | 6.71e-01 | 98.3% | 76.7% |
| 3200741 | 601.1.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C | 0.80 | 74.0 | 6.89e-01 | 100.0% | 89.7% |
| 3249523 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.80 | 71.0 | 7.06e-01 | 94.9% | 97.5% |
| 3511483 | 601.1.3.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B | 0.80 | 74.0 | 6.72e-01 | 100.0% | 76.1% |
| 3496091 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.79 | 70.0 | 6.71e-01 | 95.7% | 95.6% |
| 3255240 | 601.1.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS | 0.79 | 73.0 | 6.43e-01 | 100.0% | 71.5% |
| 3272619 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.79 | 70.0 | 7.01e-01 | 96.6% | 95.8% |
| 4399455 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.78 | 72.0 | 6.54e-01 | 100.0% | 89.7% |
| 3517672 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.78 | 72.0 | 6.62e-01 | 100.0% | 78.7% |
| 4489112 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.78 | 72.0 | 6.30e-01 | 99.1% | 81.2% |
| 3391109 | 3684.1.1.21 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › TMEM138 | 0.78 | 72.0 | 6.76e-01 | 100.0% | 99.3% |
| 4387704 | 601.1.2.5 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › TLN1-like_RS | 0.78 | 72.0 | 6.24e-01 | 100.0% | 69.1% |
| 5066789 | 601.13.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS | 0.78 | 53.0 | 6.07e-01 | 91.5% | 95.3% |
| 3768053 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.78 | 73.0 | 6.55e-01 | 100.0% | 87.7% |
| 3948656 | 601.4.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT | 0.78 | 72.0 | 6.48e-01 | 100.0% | 75.5% |
| 4184794 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.78 | 71.0 | 6.53e-01 | 100.0% | 78.7% |
| 151123 | 601.1.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS | 0.77 | 71.0 | 6.20e-01 | 100.0% | 70.0% |
| 5023098 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.77 | 58.0 | 5.70e-01 | 78.6% | 84.0% |
| 3250121 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.77 | 57.0 | 4.41e-01 | 77.8% | 37.6% |
| 3253934 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.76 | 67.0 | 6.68e-01 | 94.9% | 100.0% |
| 3416724 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.76 | 70.0 | 6.42e-01 | 100.0% | 82.7% |
| 5020411 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.76 | 69.0 | 6.38e-01 | 100.0% | 78.7% |
| 3945101 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 65.0 | 6.68e-01 | 97.4% | 97.3% |
| 5041256 | 601.4.1.91 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF30769 | 0.76 | 61.0 | 6.40e-01 | 100.0% | 95.2% |
| 4993965 | 5069.1.1.15 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm | 0.75 | 69.0 | 6.34e-01 | 100.0% | 92.0% |
| 3980116 | 601.18.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 | 0.75 | 65.0 | 6.67e-01 | 97.4% | 97.3% |
| 3398787 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.75 | 56.0 | 5.00e-01 | 77.8% | 70.6% |
| 3989674 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.75 | 64.0 | 6.37e-01 | 100.0% | 90.8% |
| 4647093 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.75 | 68.0 | 6.51e-01 | 100.0% | 89.6% |
| 3234038 | 5001.1.1.69 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd | 0.74 | 67.0 | 4.89e-01 | 100.0% | 81.2% |
| 5032992 | 192.29.1.305 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4386 | 0.74 | 67.0 | 5.47e-01 | 100.0% | 65.6% |
| 3790952 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.74 | 68.0 | 6.32e-01 | 100.0% | 85.5% |
| 3380500 | 192.29.1.34 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF677 | 0.74 | 67.0 | 5.50e-01 | 100.0% | 99.5% |
| 3332592 | 5069.1.1.62 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Chloroplast_duf | 0.73 | 63.0 | 6.52e-01 | 98.3% | 99.1% |
| 3797265 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.73 | 65.0 | 6.44e-01 | 99.1% | 97.6% |
| 5059402 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.73 | 66.0 | 6.18e-01 | 100.0% | 90.3% |
| 3513656 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.73 | 65.0 | 5.46e-01 | 97.4% | 59.0% |
| 3224746 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.72 | 65.0 | 6.45e-01 | 100.0% | 96.8% |
| 3746208 | 601.18.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 | 0.72 | 64.0 | 5.85e-01 | 100.0% | 72.7% |
| 3717915 | 601.18.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 | 0.72 | 64.0 | 6.18e-01 | 100.0% | 85.4% |
| 3607990 | 601.18.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 | 0.72 | 64.0 | 6.16e-01 | 100.0% | 86.2% |
| 4325832 | 129.1.1.5 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Ferric_reduct | 0.71 | 63.0 | 5.07e-01 | 95.7% | 57.3% |
| 3247352 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.71 | 53.0 | 5.25e-01 | 78.6% | 73.6% |
| 5009461 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.71 | 62.0 | 5.79e-01 | 100.0% | 77.2% |
| 4998695 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.70 | 63.0 | 6.33e-01 | 100.0% | 96.7% |
| 3741615 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.70 | 64.0 | 3.61e-01 | 100.0% | 8.9% |
| 3547336 | 5069.1.1.51 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Got1 | 0.69 | 61.0 | 5.85e-01 | 100.0% | 83.7% |
| 3348566 | 3291.1.1.106 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Chloroplast_duf | 0.69 | 51.0 | 4.88e-01 | 78.6% | 98.6% |
| 3235128 | 601.18.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 | 0.69 | 60.0 | 5.95e-01 | 100.0% | 89.6% |
| 3923952 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.69 | 59.0 | 5.75e-01 | 93.2% | 90.0% |
| 3953703 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.68 | 60.0 | 5.79e-01 | 96.6% | 95.5% |
| 3589541 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.68 | 59.0 | 5.04e-01 | 96.6% | 84.7% |
| 3656892 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.65 | 51.0 | 4.95e-01 | 82.9% | 77.7% |
| 3984078 | 5085.1.1.1 ↗ | a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP | 0.65 | 49.0 | 3.64e-01 | 78.6% | 82.7% |
| 3709562 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 47.0 | 4.35e-01 | 75.2% | 100.0% |
| 3455183 | 611.7.1.11 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › DUF7032 | 0.64 | 49.0 | 4.56e-01 | 85.5% | 65.5% |
| 4069307 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.61 | 47.0 | 3.72e-01 | 80.3% | 95.0% |
| 3733426 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 55.0 | 4.56e-01 | 97.4% | 59.5% |
| 3454885 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.61 | 47.0 | 4.54e-01 | 82.9% | 88.1% |
| 3677659 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.60 | 51.0 | 3.23e-01 | 95.7% | 35.3% |
| 4999398 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.53 | 46.0 | 3.61e-01 | 97.4% | 54.9% |