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FQ482085.1__CBX44540.1__P88_00290__00029

Bact-Vir

FQ482085.1__CBX44540.1__P88_00290__00029

Identity

Accession:
FQ482085 ↗
Kingdom:
phage

Quality

91.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 385-489
PDB
Domain cluster: representative
CATH (57)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1tjyA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 54.0 4.76e-01 100.0% 92.2%
1v8dC00 3.40.50.10360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein TT1679 0.59 52.0 4.29e-01 97.1% 84.6%
1rz3A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 50.0 4.17e-01 95.2% 100.0%
5l3sB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 48.0 3.81e-01 90.5% 95.7%
3clwA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.57 45.0 3.05e-01 83.8% 52.2%
4n03A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 51.0 4.29e-01 98.1% 77.8%
1npyA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 51.0 4.33e-01 98.1% 95.3%
3gbvA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 51.0 4.57e-01 100.0% 94.0%
1gu7A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 51.0 4.24e-01 100.0% 89.0%
2eihA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 49.0 4.42e-01 95.2% 100.0%
3ksmA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 50.0 4.45e-01 100.0% 98.0%
3busB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 51.0 3.86e-01 100.0% 73.6%
4rxuA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 49.0 4.10e-01 100.0% 91.7%
3slkA02 3.90.180.10 Alpha Beta › Alpha-Beta Complex › Quinone Oxidoreductase; Chain A, domain 1 › Medium-chain alcohol dehydrogenases, catalytic domain 0.56 51.0 3.56e-01 100.0% 61.2%
1ultB01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.56 49.0 3.24e-01 97.1% 27.3%
3kzwA02 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.55 43.0 3.13e-01 85.7% 81.2%
4rv9A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 50.0 4.04e-01 100.0% 87.6%
7aj0A01 3.40.720.10 Alpha Beta › 3-Layer(aba) Sandwich › Alkaline Phosphatase, subunit A › Alkaline Phosphatase, subunit A 0.55 42.0 2.93e-01 82.9% 37.8%
7tlrA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.55 50.0 3.74e-01 100.0% 70.1%
4eexA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 47.0 4.28e-01 93.3% 100.0%
1w5sA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 46.0 3.88e-01 95.2% 97.4%
1mdbA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 48.0 4.22e-01 97.1% 75.3%
1m1zA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 48.0 3.58e-01 99.0% 67.1%
2vsqA04 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 48.0 4.43e-01 98.1% 76.5%
3vtfA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 48.0 3.88e-01 99.0% 78.8%
4r0mB01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.54 48.0 3.17e-01 98.1% 27.4%
4j6fA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 46.0 4.05e-01 94.3% 89.9%
1amuA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 47.0 4.10e-01 98.1% 63.0%
4q9aA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.54 43.0 3.41e-01 86.7% 81.7%
3fpfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 47.0 3.57e-01 99.0% 59.1%
3b85A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 47.0 3.91e-01 98.1% 78.1%
2a5yC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 46.0 3.87e-01 95.2% 87.4%
1gvnD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 42.0 3.16e-01 83.8% 73.3%
2vlbC00 3.40.50.12500 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 47.0 3.68e-01 100.0% 87.3%
3e53A00 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.53 45.0 3.05e-01 97.1% 23.8%
4bjhB02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.53 44.0 4.02e-01 92.4% 88.9%
3te6A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 46.0 3.85e-01 99.0% 88.5%
2yxdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 46.0 3.91e-01 99.0% 95.5%
1zunA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 45.0 3.76e-01 97.1% 87.5%
3b1dA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 46.0 3.58e-01 98.1% 78.7%
7emyA04 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.52 46.0 3.14e-01 100.0% 41.7%
2c81A01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 46.0 3.51e-01 100.0% 60.1%
2yfkA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.52 44.0 3.64e-01 96.2% 99.5%
3etcA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.52 45.0 3.03e-01 100.0% 28.0%
4zocA02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.51 44.0 3.49e-01 100.0% 74.5%
3et4A00 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.51 43.0 3.39e-01 95.2% 78.3%
1o9gA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 46.0 3.71e-01 100.0% 85.9%
1gpjA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 45.0 4.00e-01 98.1% 97.4%
3u48A02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.51 44.0 3.37e-01 100.0% 77.2%
4d4iA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.51 44.0 3.01e-01 98.1% 25.9%
3ivrA00 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.51 45.0 3.09e-01 100.0% 44.7%
1qe5A00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.51 40.0 3.04e-01 85.7% 66.5%
1htwA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 45.0 3.96e-01 100.0% 94.3%
4wd1A01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.51 44.0 3.00e-01 99.0% 30.3%
3kw3A02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.51 43.0 3.48e-01 95.2% 100.0%
4rlqA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 44.0 3.41e-01 98.1% 51.0%
6ulwA01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.50 44.0 3.04e-01 98.1% 31.0%
ECOD (69)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4651784 2007.1.14.3 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Ferrochelatase 0.63 58.0 4.50e-01 100.0% 74.1%
3163715 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.62 46.0 4.36e-01 98.1% 65.6%
5048222 4143.1.1.0 a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like 0.61 52.0 4.69e-01 93.3% 77.9%
5049125 7550.1.1.0 a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain 0.61 35.0 3.03e-01 79.0% 36.3%
3838399 2003.1.5.8 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Ubie_methyltran 0.60 55.0 4.16e-01 100.0% 88.7%
5041206 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.59 53.0 4.34e-01 99.0% 88.2%
3926234 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.58 53.0 4.13e-01 100.0% 71.6%
3932808 101.1.2.163 alpha arrays › HTH › HTH › winged helix domain › PMT2_N 0.58 52.0 4.34e-01 100.0% 94.1%
3435692 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.58 40.0 2.64e-01 73.3% 16.4%
5017780 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.58 52.0 3.73e-01 100.0% 59.3%
5054572 2005.1.1.11 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.58 53.0 3.93e-01 100.0% 92.5%
5080006 2007.1.1.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like 0.57 44.0 3.22e-01 81.0% 76.1%
4424067 2003.1.1.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.57 52.0 4.27e-01 100.0% 80.5%
5062889 2007.1.16.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn 0.57 50.0 5.14e-01 95.2% 100.0%
3832532 4143.1.1.0 a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like 0.57 49.0 4.40e-01 96.2% 73.3%
3281710 323.1.1.20 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding,ACAS_N 0.57 51.0 3.89e-01 100.0% 52.4%
4033946 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.57 49.0 4.30e-01 100.0% 64.5%
4060903 2007.1.14.3 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Ferrochelatase 0.57 51.0 3.62e-01 100.0% 52.3%
4816339 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 44.0 4.01e-01 100.0% 61.6%
4972078 2003.1.1.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.56 50.0 4.23e-01 98.1% 85.1%
3657215 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 50.0 4.02e-01 100.0% 62.4%
3955536 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 49.0 3.82e-01 98.1% 51.5%
3952636 2007.1.14.6 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › CbiX 0.56 50.0 4.53e-01 100.0% 89.0%
3953364 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 49.0 4.07e-01 98.1% 63.7%
1297585 7581.1.1.2 a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › ketoacyl-synt 0.56 48.0 3.62e-01 96.2% 62.8%
1878152 2007.1.2.11 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 0.56 49.0 4.27e-01 99.0% 100.0%
5049643 7590.1.1.1 a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Peptidase_M29 0.56 50.0 4.25e-01 100.0% 95.4%
3800769 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.56 49.0 3.85e-01 98.1% 82.7%
3935753 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 50.0 3.93e-01 100.0% 65.9%
3205506 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 50.0 3.94e-01 100.0% 55.0%
3474700 2007.1.2.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › ANF_receptor 0.56 49.0 3.94e-01 100.0% 82.3%
4582212 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.56 49.0 4.21e-01 98.1% 74.1%
4990136 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.56 49.0 4.09e-01 98.1% 63.2%
3693858 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.55 49.0 3.42e-01 99.0% 97.7%
4320958 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 49.0 4.34e-01 100.0% 67.1%
1721648 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 41.0 3.86e-01 92.4% 64.6%
3720320 2003.1.1.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.55 49.0 4.09e-01 98.1% 86.7%
5024383 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 49.0 4.35e-01 98.1% 70.7%
3801701 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.55 48.0 3.86e-01 97.1% 54.8%
3724934 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 49.0 4.06e-01 100.0% 65.3%
5007221 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.55 48.0 3.99e-01 98.1% 62.6%
3374271 4143.1.1.0 a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like 0.55 47.0 3.72e-01 96.2% 48.0%
3280553 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.55 47.0 4.23e-01 98.1% 67.3%
3435530 2006.1.6.9 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › Copine 0.55 46.0 3.44e-01 94.3% 76.5%
4561544 2003.1.1.29 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › OCD_Mu_crystall 0.55 48.0 3.92e-01 96.2% 85.8%
4429437 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.54 48.0 4.33e-01 100.0% 74.0%
4517610 2003.1.1.5 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ADH_zinc_N 0.54 48.0 4.09e-01 100.0% 86.3%
1298650 2007.5.1.8 a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › Lipase_GDSL_2 0.54 43.0 3.41e-01 86.7% 81.7%
3957365 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 47.0 4.23e-01 98.1% 72.4%
3626720 4143.1.1.0 a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like 0.53 47.0 3.79e-01 97.1% 83.9%
3967841 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 46.0 4.23e-01 98.1% 72.9%
3279992 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.53 47.0 3.97e-01 98.1% 61.1%
1503818 2003.1.5.27 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › NAS 0.53 46.0 3.51e-01 100.0% 59.2%
3929431 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 47.0 3.30e-01 100.0% 95.7%
4990800 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.52 41.0 2.94e-01 85.7% 39.8%
3602740 2002.1.1.120 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.52 42.0 3.00e-01 89.5% 66.8%
3520195 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.52 46.0 4.05e-01 100.0% 82.5%
None 0.52 44.0 3.79e-01 95.2% 87.4%
3584161 4143.1.1.4 a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like › Pus10_N_euk 0.52 45.0 3.65e-01 100.0% 94.9%
3351875 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 46.0 3.88e-01 99.0% 63.4%
4981687 7584.1.1.0 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins 0.51 45.0 3.49e-01 100.0% 63.2%
4875207 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 45.0 3.99e-01 98.1% 68.0%
3641973 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.51 45.0 2.90e-01 100.0% 32.1%
2393001 7584.1.1.0 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins 0.51 45.0 3.81e-01 100.0% 84.4%
3971387 2005.2.1.1 a/b three-layered sandwiches › HUP domain-like › YdcF › YdcF › DUF218 0.51 44.0 3.58e-01 97.1% 58.5%
4929709 2003.1.5.12 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_N4_Mtase 0.51 43.0 3.25e-01 96.2% 61.5%
3959044 7528.1.1.0 a/b three-layered sandwiches › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains 0.51 44.0 4.00e-01 100.0% 78.7%
4355338 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.50 44.0 3.63e-01 98.1% 62.1%
5067568 7584.1.1.1 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding 0.50 44.0 3.13e-01 99.0% 38.2%
D2 medium residues 23-150
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.70 34.0 4.44e-01 90.6% 81.3%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.61 36.0 4.57e-01 96.1% 100.0%
1zp2A01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 31.0 3.27e-01 93.8% 53.0%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 34.0 3.74e-01 79.7% 68.2%
1ukfA00 3.90.70.20 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.58 34.0 2.97e-01 85.9% 38.3%
2zy9A03 1.10.357.20 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain 0.57 37.0 3.36e-01 100.0% 47.7%
4gdxA02 1.10.246.130 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain 0.57 38.0 4.06e-01 100.0% 79.3%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 35.0 3.63e-01 94.5% 66.7%
2z73B01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.55 42.0 3.11e-01 78.9% 84.4%
1qgtB00 1.10.4090.10 Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus 0.54 34.0 3.31e-01 90.6% 55.2%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.53 32.0 3.23e-01 79.7% 57.0%
1nktA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.53 46.0 4.20e-01 97.7% 96.6%
3ddlA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 40.0 3.29e-01 81.2% 90.5%
3er9B01 1.20.1270.320 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Poxvirus poly(A) polymerase, N domain 0.52 35.0 3.72e-01 90.6% 80.2%
4ys0A02 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.52 46.0 4.22e-01 97.7% 95.3%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.52 35.0 3.33e-01 93.8% 57.0%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 33.0 3.39e-01 95.3% 64.8%
4rfsS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.51 39.0 3.45e-01 79.7% 72.2%
5jajA03 1.20.1320.30 Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › 0.50 34.0 3.55e-01 93.0% 75.0%
1ivhA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 36.0 3.50e-01 94.5% 66.7%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 32.0 3.26e-01 94.5% 63.1%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4998103 3352.1.1.15 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › GT87 0.75 69.0 5.04e-01 100.0% 43.6%
4014020 192.29.1.4 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Opi1 0.60 41.0 3.76e-01 95.3% 52.9%
4019756 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.59 45.0 3.54e-01 80.5% 92.2%
3616130 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.58 39.0 3.31e-01 78.9% 42.0%
4871311 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 40.0 4.08e-01 96.9% 74.2%
3386846 5067.1.1.1 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ACR_tran 0.55 38.0 3.23e-01 93.8% 41.9%
3734736 3684.1.1.22 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › Opi1 0.55 39.0 3.71e-01 96.1% 60.0%
3833042 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.55 39.0 3.63e-01 74.2% 92.9%
4353063 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.55 39.0 3.68e-01 74.2% 84.4%
3406162 4006.1.1.13 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › DUF842 0.54 47.0 4.82e-01 96.1% 96.0%
3932144 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.53 41.0 4.30e-01 81.2% 90.4%
3613860 601.1.2.105 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Transmemb_17 0.52 34.0 3.34e-01 95.3% 60.0%
4068279 5045.1.1.1 alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.51 42.0 3.34e-01 88.3% 72.3%
3189791 601.19.1.18 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Mmc1_C 0.50 44.0 3.66e-01 96.9% 66.5%
4676230 5060.1.1.1 alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 0.50 37.0 3.16e-01 78.9% 82.2%
3368549 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.50 45.0 3.74e-01 96.9% 80.0%
D3 medium residues 151-252
PDB
Domain cluster: representative
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ggfA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.72 53.0 4.83e-01 78.4% 57.7%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.68 51.0 5.41e-01 80.4% 89.8%
6f7hA00 1.20.1080.10 Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. 0.68 53.0 3.96e-01 83.3% 87.3%
2qsbA00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.66 37.0 4.00e-01 71.6% 65.9%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.65 48.0 4.28e-01 79.4% 59.1%
7dwqL01 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.64 48.0 4.55e-01 79.4% 92.0%
7tj9A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.63 42.0 4.15e-01 99.0% 64.2%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 53.0 5.35e-01 91.2% 97.0%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 50.0 4.02e-01 87.3% 58.2%
2w2dD01 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.61 54.0 3.62e-01 99.0% 92.6%
3ug9A02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 48.0 3.70e-01 84.3% 48.9%
3bqyA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 51.0 4.51e-01 92.2% 66.0%
2iw3A02 1.20.1390.20 Mainly Alpha › Up-down Bundle › PWI domain › 0.61 38.0 3.98e-01 76.5% 70.0%
6dlzA01 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.60 48.0 3.94e-01 84.3% 91.2%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.60 44.0 4.74e-01 79.4% 91.8%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 46.0 4.65e-01 81.4% 98.0%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.59 45.0 4.34e-01 82.4% 92.4%
4h33A00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 40.0 4.28e-01 85.3% 79.1%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 47.0 4.34e-01 87.3% 83.8%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.58 42.0 4.30e-01 94.1% 77.8%
4tkrA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.58 47.0 3.90e-01 88.2% 52.5%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.57 45.0 3.85e-01 85.3% 81.1%
6ko8A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 46.0 3.77e-01 86.3% 60.0%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 42.0 4.24e-01 78.4% 90.2%
3owaA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.57 46.0 4.22e-01 89.2% 71.0%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.57 44.0 4.07e-01 84.3% 80.0%
2x6hA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.57 43.0 3.60e-01 82.4% 46.2%
3dewA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 45.0 4.12e-01 88.2% 81.4%
1evsA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 45.0 3.80e-01 84.3% 66.3%
8h6rA01 1.20.930.10 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.56 43.0 4.61e-01 97.1% 96.5%
6orkA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 36.0 2.70e-01 96.1% 28.6%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 39.0 3.98e-01 82.4% 93.1%
4dvyP01 1.10.357.130 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.52 41.0 3.43e-01 89.2% 84.3%
3sl9B00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.51 38.0 3.24e-01 78.4% 47.9%
3v9pB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 37.0 3.06e-01 77.5% 44.1%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.50 39.0 4.20e-01 98.0% 97.7%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3254475 109.4.1.266 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › XMAP215_CLASP_TOG 0.69 55.0 4.00e-01 85.3% 55.7%
3644241 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.65 49.0 4.60e-01 79.4% 95.2%
4042547 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.65 55.0 4.53e-01 92.2% 86.4%
3495156 109.58.1.1 alpha superhelices › Repetitive alpha hairpins › DNA repair protein Rev1 C-terminal domain › DNA repair protein Rev1 C-terminal domain › REV1_C 0.65 49.0 5.31e-01 79.4% 98.8%
4955536 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.63 52.0 4.05e-01 88.2% 81.4%
3612915 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 50.0 4.99e-01 84.3% 98.1%
4066169 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.63 55.0 3.39e-01 98.0% 29.2%
3532664 3755.3.1.391 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › USHBP1_PDZ-bd 0.63 38.0 3.41e-01 71.6% 43.6%
3566007 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.61 48.0 4.65e-01 84.3% 89.6%
5029968 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.61 50.0 3.79e-01 91.2% 71.4%
5012345 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.61 51.0 3.80e-01 91.2% 71.8%
3668856 604.5.1.7 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ALMT 0.61 47.0 4.58e-01 83.3% 90.4%
3808 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.60 48.0 4.77e-01 84.3% 96.2%
3282883 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.60 50.0 3.69e-01 91.2% 67.9%
3935032 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.60 46.0 4.64e-01 81.4% 95.2%
3617333 174.1.1.44 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF30976 0.60 46.0 3.71e-01 81.4% 71.5%
3956684 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.60 45.0 3.93e-01 82.4% 82.4%
5044572 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.59 46.0 4.63e-01 83.3% 99.0%
5016617 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.59 49.0 3.63e-01 90.2% 68.0%
4018180 4121.1.1.0 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.59 47.0 3.51e-01 85.3% 44.3%
3470544 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.59 42.0 4.36e-01 74.5% 97.9%
3962012 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.58 46.0 4.72e-01 85.3% 90.5%
4001943 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.58 44.0 4.18e-01 80.4% 82.5%
3442429 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 49.0 4.08e-01 94.1% 80.0%
3987319 604.10.1.1 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA 0.57 46.0 4.51e-01 86.3% 88.1%
3909538 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 44.0 4.46e-01 84.3% 95.2%
3591589 5050.1.1.28 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 0.57 42.0 3.47e-01 80.4% 53.0%
3939816 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 45.0 4.25e-01 85.3% 90.0%
3478959 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.56 45.0 3.72e-01 88.2% 80.0%
5072101 3651.1.1.1 alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B 0.56 43.0 4.18e-01 86.3% 74.8%
4026893 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.55 44.0 3.55e-01 86.3% 82.0%
3806870 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.55 44.0 4.48e-01 99.0% 87.0%
3498125 604.1.1.193 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › HB_ELP1 0.55 44.0 3.73e-01 88.2% 89.4%
3585209 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 45.0 4.10e-01 88.2% 87.4%
3957035 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.55 44.0 3.35e-01 87.3% 88.8%
4588403 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.54 43.0 3.84e-01 86.3% 76.7%
5001354 633.12.1.1 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 0.54 39.0 4.16e-01 75.5% 87.6%
3620867 5048.1.1.1 alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP 0.54 47.0 3.50e-01 99.0% 80.6%
3503307 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.53 41.0 3.61e-01 84.3% 82.5%
4680153 7015.1.1.1 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC 0.52 40.0 3.70e-01 84.3% 87.9%
3513907 109.4.1.46 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › IBN_N 0.52 46.0 3.30e-01 100.0% 38.7%
5068709 633.12.1.0 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.51 38.0 4.07e-01 79.4% 93.3%
3700350 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 46.0 4.29e-01 100.0% 96.0%
3269220 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.50 39.0 3.02e-01 83.3% 86.0%
D4 medium residues 253-353
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fkaG00 1.10.455.10 Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 0.56 46.0 4.31e-01 91.1% 75.0%
1jb0K00 1.20.860.20 Mainly Alpha › Up-down Bundle › Alpha-t-alpha › Photosystem I PsaK, reaction centre 0.56 27.0 3.71e-01 71.3% 100.0%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.55 37.0 3.93e-01 89.1% 81.2%
2o7gA00 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.55 39.0 4.14e-01 96.0% 85.2%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.54 32.0 3.48e-01 90.1% 69.9%
1kyoF00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.54 36.0 3.99e-01 70.3% 93.2%
1sdiA00 1.10.3890.10 Mainly Alpha › Orthogonal Bundle › YcfC-like › HflD-like 0.53 39.0 3.16e-01 78.2% 79.3%
6pmiF01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.53 36.0 3.93e-01 88.1% 87.5%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 43.0 4.29e-01 90.1% 91.3%
6ldiF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 35.0 3.62e-01 89.1% 71.9%
5gl7A01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 40.0 3.44e-01 85.1% 50.0%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.52 40.0 3.76e-01 83.2% 77.3%
2qguA02 1.10.10.640 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › phospholipid-binding protein 0.51 37.0 4.11e-01 91.1% 97.4%
3jz0A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 39.0 3.59e-01 97.0% 63.1%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.51 43.0 4.32e-01 95.0% 95.1%
1z72A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.51 40.0 3.24e-01 88.1% 50.9%
5jazA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.50 36.0 3.74e-01 92.1% 82.4%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3269505 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.63 42.0 4.29e-01 93.1% 69.0%
4944039 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.61 48.0 3.86e-01 85.1% 77.8%
3496942 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.61 48.0 3.62e-01 88.1% 68.0%
3191085 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.60 48.0 3.68e-01 89.1% 66.0%
3689634 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 49.0 3.89e-01 95.0% 80.0%
3736564 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 48.0 3.80e-01 95.0% 69.8%
3293161 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.58 47.0 3.62e-01 87.1% 38.3%
3965343 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.57 43.0 3.56e-01 82.2% 45.1%
5009990 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 46.0 3.86e-01 94.1% 86.7%
3544073 207.1.1.63 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_6,LRR_8 0.56 45.0 2.92e-01 87.1% 76.3%
5079257 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 41.0 3.38e-01 77.2% 76.9%
3804970 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.56 47.0 3.71e-01 97.0% 71.2%
5052372 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.56 45.0 3.62e-01 89.1% 86.7%
3957267 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.56 47.0 3.66e-01 96.0% 72.9%
4102360 601.17.1.1 alpha bundles › Four-helical up-and-down bundle › Group V grass pollen allergen › Group V grass pollen allergen › Pollen_allerg_2 0.55 38.0 3.63e-01 70.3% 71.7%
3301886 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.55 47.0 3.63e-01 97.0% 68.4%
3727453 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 46.0 3.69e-01 96.0% 72.4%
4663875 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.55 37.0 2.81e-01 86.1% 28.3%
3688111 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 40.0 3.45e-01 86.1% 45.9%
3790651 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 45.0 3.60e-01 93.1% 70.2%
5009721 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.55 48.0 3.80e-01 100.0% 85.9%
3730728 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 44.0 3.70e-01 91.1% 81.6%
3687819 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.54 46.0 3.51e-01 95.0% 65.1%
4164998 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.54 34.0 3.49e-01 86.1% 64.0%
3185600 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 45.0 3.50e-01 93.1% 70.2%
4144086 166.1.1.1 alpha superhelices › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › 1-deoxy-D-xylulose-5-phosphate reductoisomerase-C › DXPR_C 0.54 37.0 3.72e-01 92.1% 71.0%
None 0.53 42.0 3.26e-01 100.0% 38.6%
4258677 142.1.1.0 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.53 34.0 2.74e-01 89.1% 28.9%
5034878 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 43.0 3.58e-01 90.1% 84.7%
3625921 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.53 44.0 3.59e-01 94.1% 76.1%
3640113 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 44.0 3.40e-01 93.1% 66.9%
134276 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.53 43.0 4.29e-01 90.1% 91.3%
3469670 1015.1.1.9 alpha complex topology › Insulin-induced gene (Insig) homologs › Insulin-induced gene (Insig) homologs › Insulin-induced gene (Insig) homologs › CPP1-like 0.53 38.0 3.77e-01 76.2% 84.3%
3722700 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 44.0 3.62e-01 97.0% 80.8%
3970629 5050.1.1.60 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 0.52 45.0 3.61e-01 97.0% 78.6%
3172285 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 43.0 3.26e-01 93.1% 63.7%
5080134 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 42.0 3.45e-01 89.1% 46.8%
5054868 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 43.0 3.54e-01 96.0% 78.0%
3733546 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 43.0 3.36e-01 96.0% 67.8%
4010940 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 42.0 3.54e-01 92.1% 83.2%
3630464 5068.1.1.1 alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C 0.51 42.0 4.13e-01 94.1% 89.1%
3632884 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 43.0 3.55e-01 97.0% 81.0%
4953230 3646.1.1.1 alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › CbiQ 0.51 38.0 3.06e-01 83.2% 37.3%
4614029 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.50 41.0 3.39e-01 90.1% 91.1%
3725616 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.50 43.0 3.75e-01 96.0% 71.9%
3396796 601.1.1.43 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Serendipity_A 0.50 37.0 3.56e-01 79.2% 92.5%
3228202 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.50 39.0 3.45e-01 83.2% 84.0%
4876272 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.50 41.0 4.23e-01 100.0% 92.8%