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Filtrate_w_scaffold_1_prodigal-single.1__X__X__00443

Bact-Vir

Filtrate_w_scaffold_1_prodigal-single.1__X__X__00443

Identity

Kingdom:
phage

Quality

89.6 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-104
PDB
Domain cluster: representative
CATH (88)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.93 58.0 6.70e-01 100.0% 84.4%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.91 60.0 6.30e-01 92.2% 73.9%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.91 51.0 6.81e-01 80.4% 100.0%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.91 58.0 6.64e-01 94.1% 85.7%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.89 66.0 5.69e-01 89.2% 53.1%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.88 55.0 5.99e-01 97.1% 75.6%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.86 68.0 6.59e-01 90.2% 74.1%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.86 67.0 6.59e-01 90.2% 76.6%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.85 66.0 6.02e-01 100.0% 62.4%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.84 51.0 5.45e-01 93.1% 70.0%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.83 74.0 5.57e-01 100.0% 42.3%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.83 73.0 4.96e-01 100.0% 28.6%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 80.0 5.99e-01 100.0% 76.7%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.83 65.0 6.79e-01 100.0% 89.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 78.0 5.75e-01 100.0% 44.9%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.81 77.0 5.76e-01 100.0% 58.7%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 58.0 5.82e-01 85.3% 72.4%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.81 74.0 5.03e-01 100.0% 31.4%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.81 75.0 5.91e-01 100.0% 61.4%
4cgkA01 6.10.250.3150 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.80 75.0 5.77e-01 100.0% 65.4%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 72.0 7.15e-01 99.0% 90.6%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.80 50.0 4.54e-01 78.4% 49.2%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 55.0 5.45e-01 93.1% 67.3%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.80 65.0 6.57e-01 93.1% 86.1%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.80 58.0 6.18e-01 100.0% 85.6%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 75.0 5.61e-01 100.0% 50.2%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.79 45.0 5.02e-01 77.5% 71.2%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 68.0 6.87e-01 99.0% 90.3%
3ofnY00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.79 73.0 7.02e-01 97.1% 97.4%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 75.0 5.95e-01 100.0% 55.3%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.79 70.0 5.39e-01 99.0% 45.1%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.79 48.0 5.03e-01 87.3% 66.7%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.79 49.0 4.34e-01 95.1% 44.8%
3smtA02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.78 58.0 4.84e-01 76.5% 60.4%
4wpcA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 73.0 5.17e-01 100.0% 36.0%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.78 73.0 5.44e-01 100.0% 50.6%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.78 73.0 7.17e-01 99.0% 99.1%
7zdtD01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.78 65.0 4.48e-01 89.2% 69.9%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.77 72.0 6.31e-01 100.0% 91.1%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.77 59.0 6.52e-01 95.1% 100.0%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 51.0 5.32e-01 87.3% 71.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.77 61.0 6.56e-01 88.2% 96.6%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.77 50.0 4.99e-01 88.2% 63.6%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.77 57.0 5.28e-01 93.1% 62.2%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 71.0 5.12e-01 100.0% 38.7%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 64.0 6.71e-01 93.1% 94.7%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 71.0 5.13e-01 100.0% 39.3%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.76 48.0 4.22e-01 91.2% 44.8%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.76 53.0 5.17e-01 97.1% 66.4%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 61.0 6.12e-01 92.2% 83.5%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.76 70.0 5.89e-01 99.0% 85.7%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 68.0 4.97e-01 100.0% 38.7%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.75 67.0 6.94e-01 94.1% 100.0%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 54.0 6.23e-01 73.5% 100.0%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 48.0 5.84e-01 71.6% 100.0%
3errA01 1.20.920.60 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.75 63.0 4.90e-01 89.2% 94.7%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.75 61.0 6.49e-01 91.2% 100.0%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 57.0 5.75e-01 96.1% 81.4%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 69.0 5.86e-01 100.0% 69.2%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 69.0 4.92e-01 100.0% 41.8%
1mabG00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.74 67.0 6.30e-01 99.0% 91.1%
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.74 61.0 6.40e-01 99.0% 100.0%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 65.0 6.60e-01 98.0% 97.0%
1zvuA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.73 58.0 5.15e-01 82.4% 81.4%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.73 67.0 6.11e-01 100.0% 84.3%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.73 68.0 4.87e-01 100.0% 38.0%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.72 65.0 4.55e-01 100.0% 70.5%
4dylA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 62.0 4.66e-01 100.0% 38.4%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.72 64.0 6.03e-01 93.1% 82.4%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.72 65.0 4.61e-01 100.0% 33.7%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 66.0 4.92e-01 100.0% 42.9%
3u0cA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.72 63.0 5.54e-01 100.0% 65.6%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.71 66.0 4.57e-01 100.0% 97.5%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.71 65.0 4.87e-01 100.0% 42.0%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 66.0 5.58e-01 100.0% 67.7%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.71 57.0 4.99e-01 93.1% 58.5%
7zd5C01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.71 63.0 4.39e-01 100.0% 31.2%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.71 51.0 4.65e-01 94.1% 57.0%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.71 47.0 5.32e-01 100.0% 89.7%
1ek9A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.69 55.0 3.57e-01 85.3% 20.3%
4mycA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.68 59.0 4.19e-01 98.0% 68.9%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.66 60.0 4.02e-01 100.0% 27.4%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.65 55.0 5.62e-01 97.1% 93.9%
5ziyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.65 60.0 4.78e-01 100.0% 88.1%
6bl6B01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.64 59.0 4.10e-01 100.0% 59.5%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.62 50.0 4.56e-01 85.3% 79.4%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 51.0 4.01e-01 100.0% 44.8%
1f45B00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 45.0 4.10e-01 88.2% 68.4%
ECOD (89)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3423402 604.7.1.1 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA 0.89 66.0 7.27e-01 98.0% 92.9%
3620978 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.87 75.0 5.05e-01 100.0% 28.4%
4446057 192.8.1.345 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › PF30463 0.86 77.0 5.85e-01 100.0% 44.6%
3385717 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 81.0 6.56e-01 100.0% 58.2%
3976632 3291.1.1.4 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.86 76.0 6.55e-01 100.0% 63.3%
3402974 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 77.0 6.48e-01 100.0% 61.3%
3840064 192.24.1.0 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain 0.85 74.0 7.65e-01 90.2% 96.8%
3294656 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 81.0 5.25e-01 100.0% 41.4%
3972622 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.84 67.0 6.78e-01 100.0% 85.0%
3207569 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 80.0 6.21e-01 100.0% 51.5%
4321938 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.84 81.0 6.64e-01 100.0% 68.5%
3763261 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 81.0 6.01e-01 100.0% 81.4%
3612941 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 73.0 6.51e-01 100.0% 67.9%
3962991 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 80.0 6.20e-01 100.0% 61.5%
4571188 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 78.0 7.13e-01 100.0% 83.8%
3696958 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 79.0 5.00e-01 100.0% 80.7%
4479398 3755.1.1.8 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ 0.83 73.0 6.39e-01 100.0% 65.5%
3870915 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 78.0 6.04e-01 99.0% 75.0%
4972577 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.82 78.0 5.56e-01 100.0% 38.5%
3699463 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.82 77.0 5.85e-01 100.0% 54.9%
5006401 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.81 78.0 6.74e-01 100.0% 94.5%
4516566 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.81 76.0 6.07e-01 100.0% 66.8%
3187793 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.81 77.0 5.91e-01 100.0% 58.6%
4395939 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.81 76.0 5.54e-01 100.0% 87.1%
4501248 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.81 77.0 6.32e-01 100.0% 73.5%
3443143 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 77.0 6.26e-01 100.0% 59.4%
3711596 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.81 76.0 6.40e-01 100.0% 70.6%
4950970 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 74.0 4.94e-01 100.0% 78.9%
3657504 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.81 76.0 6.77e-01 98.0% 74.1%
4932148 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.80 76.0 7.04e-01 100.0% 90.4%
4821107 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.80 65.0 4.46e-01 98.0% 27.2%
4024074 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 76.0 6.18e-01 100.0% 58.3%
4022306 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.80 75.0 6.50e-01 100.0% 68.0%
3167394 874.1.1.0 a+b duplicates or obligate multimers › Smc hinge domain › Smc hinge domain › Smc hinge domain 0.80 76.0 5.44e-01 100.0% 41.9%
3193556 2004.1.1.481 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 0.80 75.0 4.37e-01 100.0% 18.3%
4581983 5086.1.1.13 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › T3SSipB 0.80 67.0 5.96e-01 100.0% 65.0%
4541195 3755.3.1.470 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB 0.80 67.0 6.11e-01 100.0% 70.0%
3935140 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.79 75.0 6.04e-01 100.0% 76.7%
5036054 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.79 74.0 4.71e-01 100.0% 40.1%
5008718 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.79 74.0 4.69e-01 100.0% 22.2%
3699458 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 74.0 5.23e-01 100.0% 35.8%
3178900 192.2.1.30 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Uds1 0.79 72.0 6.33e-01 100.0% 68.3%
5012473 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.79 72.0 6.97e-01 95.1% 90.9%
4360632 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.79 74.0 6.40e-01 100.0% 68.0%
3932987 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.79 74.0 5.32e-01 100.0% 39.6%
5069236 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 74.0 6.03e-01 100.0% 65.7%
3861313 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 63.0 6.01e-01 83.3% 89.6%
3249317 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 74.0 6.21e-01 100.0% 72.5%
4295915 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 73.0 6.64e-01 100.0% 89.2%
3975632 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.78 71.0 5.71e-01 100.0% 53.5%
3973283 325.1.7.27 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_AprE 0.78 71.0 5.61e-01 99.0% 50.8%
3594672 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.78 72.0 5.33e-01 100.0% 43.3%
3935064 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 72.0 5.07e-01 100.0% 78.3%
3858356 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.77 70.0 6.21e-01 100.0% 69.0%
3936021 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.77 71.0 5.53e-01 100.0% 53.8%
3421052 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 60.0 4.48e-01 98.0% 35.3%
3690657 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.77 65.0 5.77e-01 92.2% 65.0%
5049284 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.77 68.0 6.46e-01 100.0% 82.5%
4136919 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.76 70.0 5.70e-01 100.0% 55.7%
3921243 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.76 72.0 4.22e-01 100.0% 15.1%
4523639 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.76 69.0 5.51e-01 99.0% 52.1%
3872357 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.76 69.0 4.06e-01 100.0% 61.1%
4576949 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.76 71.0 6.06e-01 100.0% 68.4%
4246573 3755.1.1.8 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ 0.75 68.0 5.94e-01 100.0% 67.3%
4986986 3633.1.1.0 alpha duplicates or obligate multimers › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor 0.75 69.0 5.39e-01 100.0% 60.5%
3852269 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 69.0 6.04e-01 100.0% 70.3%
3615972 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 70.0 5.59e-01 100.0% 55.1%
3521699 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.74 68.0 4.68e-01 100.0% 37.9%
3586751 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.74 67.0 5.54e-01 100.0% 57.8%
3598167 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.74 68.0 5.91e-01 100.0% 72.7%
4116038 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.73 65.0 5.70e-01 100.0% 69.0%
3263540 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 66.0 4.25e-01 99.0% 51.9%
3235287 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 66.0 4.76e-01 100.0% 36.4%
3715936 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 65.0 5.41e-01 99.0% 84.6%
3972236 3755.3.1.42 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CheZ 0.72 65.0 5.35e-01 99.0% 66.7%
5070736 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.71 65.0 5.18e-01 100.0% 73.0%
3943772 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.71 63.0 5.10e-01 98.0% 52.1%
3717903 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.69 63.0 4.12e-01 100.0% 78.8%
4642325 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.69 62.0 5.77e-01 100.0% 92.3%
None 0.69 59.0 4.63e-01 94.1% 46.4%
3842667 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 62.0 5.19e-01 100.0% 58.9%
3470751 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.69 62.0 5.30e-01 99.0% 73.8%
3911717 192.29.1.25 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CA109-like 0.69 63.0 5.00e-01 100.0% 55.0%
3968781 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.68 60.0 5.41e-01 99.0% 73.8%
5056868 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.68 63.0 4.15e-01 100.0% 42.6%
3971049 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.67 62.0 4.36e-01 100.0% 42.4%
3636338 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.65 57.0 5.39e-01 98.0% 82.4%
3205695 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 57.0 4.30e-01 100.0% 40.4%
3584894 605.1.1.238 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › CNNM 0.63 48.0 5.13e-01 99.0% 88.9%
D2 medium residues 107-174
PDB
Domain cluster: representative
CATH (46)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.82 48.0 4.81e-01 100.0% 58.8%
2avuB00 1.10.4000.10 Mainly Alpha › Orthogonal Bundle › Flagellar transcriptional activator fold › Flagellar transcriptional activator FlhD 0.76 64.0 5.44e-01 95.6% 58.7%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.75 58.0 5.79e-01 91.2% 78.9%
3mhsB00 1.10.246.140 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1 0.74 40.0 3.61e-01 100.0% 39.6%
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 52.0 4.99e-01 83.8% 64.9%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.73 58.0 4.48e-01 92.6% 39.7%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.70 62.0 5.58e-01 100.0% 71.7%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.70 60.0 5.05e-01 97.1% 57.1%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 60.0 5.13e-01 97.1% 60.7%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.69 57.0 4.84e-01 91.2% 99.1%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 55.0 5.33e-01 100.0% 78.4%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.68 59.0 4.99e-01 97.1% 58.7%
7dluA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 58.0 4.94e-01 100.0% 59.0%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.68 49.0 5.20e-01 83.8% 86.7%
2qe7G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.68 59.0 5.27e-01 97.1% 92.8%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.67 56.0 5.68e-01 97.1% 92.4%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 57.0 5.41e-01 91.2% 87.2%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 55.0 4.34e-01 100.0% 44.9%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.66 53.0 4.65e-01 98.5% 57.5%
3udcA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 56.0 4.68e-01 100.0% 55.7%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 54.0 4.66e-01 97.1% 57.1%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 55.0 4.81e-01 98.5% 62.7%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.65 51.0 5.43e-01 89.7% 96.7%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.65 50.0 3.95e-01 89.7% 40.4%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.65 47.0 4.00e-01 88.2% 47.3%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 55.0 3.91e-01 92.6% 71.6%
2wapA00 3.90.1300.10 Alpha Beta › Alpha-Beta Complex › Amidase signature (AS) enzymes › Amidase signature (AS) domain 0.64 59.0 3.43e-01 100.0% 31.6%
2uxwA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 57.0 4.19e-01 100.0% 72.6%
2q1kA00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.64 46.0 5.09e-01 85.3% 100.0%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.63 50.0 5.16e-01 100.0% 92.3%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.63 52.0 5.25e-01 100.0% 91.2%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.62 57.0 5.26e-01 100.0% 81.2%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 52.0 4.49e-01 100.0% 58.9%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.62 49.0 5.00e-01 95.6% 92.2%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.61 56.0 4.45e-01 100.0% 59.4%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 48.0 4.07e-01 97.1% 50.8%
3r6nB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 52.0 3.66e-01 98.5% 59.4%
3h1nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 47.0 3.94e-01 86.8% 92.5%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.60 49.0 4.34e-01 91.2% 63.6%
2uuzB00 1.10.10.2020 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Host-nuclease inhibitor protein Gam 0.59 55.0 5.06e-01 100.0% 83.5%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.58 50.0 3.92e-01 94.1% 55.3%
6w0pB01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.58 48.0 3.19e-01 94.1% 98.3%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.57 47.0 3.80e-01 95.6% 47.0%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.57 48.0 4.73e-01 100.0% 87.8%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.51 36.0 3.09e-01 88.2% 47.2%
3of4A00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.50 45.0 3.17e-01 100.0% 60.9%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3709611 5073.1.1.7 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › PhoLip_ATPase_C 0.76 64.0 4.03e-01 100.0% 17.6%
5018194 4307.1.1.41 alpha duplicates or obligate multimers › EB1 dimerisation domain-like › EB1 dimerisation domain-like › EB1 dimerisation domain-like › DUF1016_N 0.75 63.0 4.92e-01 91.2% 64.3%
5056476 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.74 67.0 6.50e-01 98.5% 89.3%
4950709 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.72 60.0 6.19e-01 97.1% 95.4%
3202557 605.1.1.124 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Brr6_like_C_C 0.72 62.0 5.41e-01 100.0% 64.0%
3774851 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.72 57.0 3.95e-01 97.1% 27.0%
3610875 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.72 65.0 5.28e-01 100.0% 54.4%
3686025 604.7.1.10 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › Tmemb_170 0.71 64.0 4.85e-01 100.0% 43.9%
5050536 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 51.0 5.08e-01 91.2% 74.3%
5060846 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.68 51.0 4.91e-01 89.7% 70.7%
4238947 304.8.1.65 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT, PF27446 0.68 40.0 2.65e-01 98.5% 15.7%
4936497 150.1.1.14 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like 0.68 56.0 5.17e-01 95.6% 69.3%
3823703 212.1.1.22 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Topo-VIb_trans 0.68 58.0 4.04e-01 100.0% 28.7%
5050301 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 58.0 5.42e-01 95.6% 86.9%
5035200 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.67 56.0 5.43e-01 97.1% 84.0%
4951992 5041.1.1.55 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › DUF1622 0.67 54.0 4.71e-01 97.1% 59.0%
4828003 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.67 57.0 4.71e-01 100.0% 52.9%
4937584 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.66 56.0 5.43e-01 98.5% 84.0%
4957808 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.66 54.0 4.66e-01 100.0% 58.1%
3278248 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.66 58.0 5.51e-01 97.1% 83.7%
1252012 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.65 56.0 4.91e-01 100.0% 64.6%
5044927 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.65 51.0 5.33e-01 95.6% 98.3%
3241303 632.7.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.64 55.0 5.19e-01 95.6% 80.0%
4026843 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.64 54.0 5.44e-01 98.5% 90.0%
3175481 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.64 57.0 4.15e-01 98.5% 47.2%
3339474 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.64 55.0 4.46e-01 100.0% 51.2%
3590755 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.63 49.0 5.19e-01 92.6% 98.3%
3602948 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.63 57.0 5.51e-01 100.0% 92.0%
5012522 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.63 53.0 4.83e-01 95.6% 68.9%
3968647 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.63 49.0 4.98e-01 91.2% 89.2%
3723174 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.63 55.0 5.35e-01 98.5% 89.3%
3701892 604.39.1.0 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters 0.62 53.0 3.92e-01 100.0% 37.6%
3785340 7581.1.1.3 a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › ketoacyl-synt,Ketoacyl-synt_C 0.62 56.0 3.15e-01 100.0% 8.9%
4024699 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.62 49.0 3.84e-01 100.0% 40.7%
3610233 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 53.0 4.36e-01 97.1% 52.8%
3441963 605.1.1.222 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF4220 0.61 53.0 4.41e-01 95.6% 57.4%
4016091 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.61 54.0 5.04e-01 100.0% 81.2%
5048328 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.61 49.0 4.67e-01 100.0% 77.5%
3575045 267.1.1.3 a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase 0.60 56.0 3.49e-01 100.0% 20.3%
5034312 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.59 51.0 4.36e-01 100.0% 61.7%
4958384 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.57 48.0 4.44e-01 100.0% 72.2%
3270180 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.57 50.0 4.55e-01 97.1% 73.3%
3331225 5042.1.1.0 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region 0.54 44.0 4.45e-01 100.0% 88.6%
1566346 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.53 44.0 4.40e-01 97.1% 93.0%
3323416 3831.1.1.7 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › DUF842 0.52 46.0 3.98e-01 98.5% 76.2%
D3 medium residues 175-242
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2i52B00 3.30.1300.20 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 7,8-dihydroneopterin aldolase (MptD) 0.63 50.0 4.25e-01 88.2% 87.1%
1wnhA01 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.63 56.0 4.92e-01 100.0% 81.0%
1a8dA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.62 42.0 2.84e-01 82.4% 19.1%
1jhnA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.61 44.0 3.10e-01 79.4% 27.6%
6lofA00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.60 41.0 3.15e-01 72.1% 71.6%
2ciuA00 3.10.450.320 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Mitochondrial import inner membrane translocase subunit Tim21 0.59 50.0 4.26e-01 100.0% 80.5%
2zzjA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.59 46.0 3.15e-01 83.8% 25.6%
3q90B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 52.0 4.23e-01 100.0% 84.6%
4n6tA00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 52.0 4.95e-01 100.0% 89.9%
3lydA01 3.40.1000.10 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich 0.59 50.0 4.05e-01 100.0% 47.9%
2je6A01 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.59 45.0 3.03e-01 82.4% 42.5%
7wa9A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.58 50.0 4.04e-01 100.0% 62.4%
3k1lA01 3.30.457.40 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › 0.58 40.0 3.68e-01 76.5% 54.3%
2l4vA00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 50.0 4.06e-01 100.0% 70.4%
4k17B01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 44.0 3.75e-01 100.0% 52.3%
1v9kA00 3.30.2350.10 Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › Pseudouridine synthase 0.56 39.0 2.80e-01 75.0% 72.7%
3jr1A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 48.0 4.30e-01 100.0% 96.0%
3ci0J01 3.10.610.10 Alpha Beta › Roll › Pili subunits › GSPII I/J protein-like 0.55 47.0 4.16e-01 100.0% 76.9%
2v73A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.55 42.0 3.07e-01 82.4% 38.3%
3i1aA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.54 46.0 4.14e-01 100.0% 93.2%
1h2iA01 3.30.390.80 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › DNA repair protein Rad52/59/22 0.54 43.0 3.49e-01 92.6% 60.1%
4aghA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.53 36.0 3.50e-01 100.0% 62.5%
2kdyA01 2.60.40.1980 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 44.0 3.56e-01 100.0% 53.8%
3uiuA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 43.0 3.90e-01 100.0% 94.8%
3k8aB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.51 41.0 3.61e-01 89.7% 82.5%
2retA00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.50 41.0 3.85e-01 89.7% 72.6%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3492622 3338.1.1.0 a+b two layers › Fragilysin-3 prodomain-like › Fragilysin-3 prodomain › Fragilysin-3 prodomain 0.62 57.0 4.59e-01 100.0% 95.1%
3962603 881.1.1.0 a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.62 51.0 4.45e-01 100.0% 59.1%
3836347 243.3.1.26 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › protein_MS5 0.61 53.0 4.42e-01 100.0% 71.2%
4226938 331.10.1.2 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase › AdoMet_dc 0.60 50.0 3.59e-01 100.0% 29.8%
3430469 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.60 53.0 4.69e-01 100.0% 75.8%
3973638 331.10.1.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › S-adenosylmethionine decarboxylase 0.59 48.0 3.45e-01 100.0% 28.8%
4415556 331.10.2.1 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase › AdoMet_dc 0.59 47.0 3.53e-01 100.0% 31.4%
3192871 220.1.1.194 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_2nd_LRR 0.59 50.0 3.82e-01 100.0% 50.9%
383967 216.1.1.7 a+b two layers › UBC-like › UBC-like › UBC-like › FANCL_d1 0.58 40.0 3.71e-01 76.5% 55.6%
3238125 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 50.0 3.01e-01 100.0% 19.6%
3556738 220.1.1.40 beta barrels › PH domain-like › PH domain-like › PH domain-like › OCRL_clath_bd 0.56 41.0 3.38e-01 94.1% 42.4%
3614586 214.1.1.0 a+b two layers › SH2 › SH2 › SH2 0.56 40.0 3.29e-01 76.5% 43.2%
3710585 881.1.1.0 a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.55 45.0 3.93e-01 100.0% 72.5%
3517402 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.54 47.0 4.08e-01 100.0% 70.9%
4960428 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.54 46.0 3.24e-01 100.0% 89.6%
4960364 243.1.1.23 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF3887 0.54 46.0 4.07e-01 100.0% 94.3%
5072644 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.53 40.0 3.38e-01 85.3% 87.7%
4019606 220.1.1.63 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_NF1 0.53 40.0 3.50e-01 86.8% 50.4%
3478795 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 41.0 3.05e-01 83.8% 45.1%
3240661 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 41.0 3.07e-01 92.6% 97.7%
3581025 376.1.2.15 few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › SOS1_NGEF_PH 0.53 41.0 3.23e-01 88.2% 38.1%
3939474 9.1.1.0 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.53 43.0 3.53e-01 97.1% 51.7%
3342587 243.3.1.12 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › SQAPI 0.53 44.0 3.99e-01 100.0% 72.0%
3245468 9.1.1.0 beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.52 44.0 3.76e-01 100.0% 59.2%
4572902 5.1.4.169 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RSE1_2nd 0.52 45.0 2.83e-01 100.0% 24.4%
3494609 220.1.1.115 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_19 0.52 40.0 2.99e-01 83.8% 45.1%
3263391 220.1.1.66 beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH 0.52 44.0 3.79e-01 97.1% 63.6%
3492201 295.1.1.1 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PC4 0.51 36.0 3.51e-01 76.5% 66.7%
4263663 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.51 43.0 3.40e-01 100.0% 48.8%
3246329 59.1.2.0 beta complex topology › triple barrel › triple barrel › RNase H2 subunits B and C 0.51 45.0 4.48e-01 100.0% 95.7%
4587403 3321.1.1.1 a+b two layers › Meander beta sheet domain in fatty acid synthase subunit beta › Meander beta sheet domain in fatty acid synthase subunit beta › Meander beta sheet domain in fatty acid synthase subunit beta › FAS_meander 0.51 42.0 3.39e-01 100.0% 60.0%
3511457 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.50 34.0 2.83e-01 72.1% 70.4%
4969244 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.50 40.0 2.69e-01 100.0% 34.1%
3473585 220.1.1.66 beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH 0.50 39.0 3.14e-01 86.8% 43.6%
3645476 295.1.1.1 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PC4 0.50 35.0 3.17e-01 100.0% 51.0%