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Filtrate_w_scaffold_3_prodigal-single.1__X__X__00385
Bact-VirFiltrate_w_scaffold_3_prodigal-single.1__X__X__00385
Identity
- Kingdom:
- phage
Quality
92.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-29_85-120
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02146.24 best | SIR2 | 40.6 | 3.70e-10 | 98.5% | 22.2% |
CATH (72)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u31A01 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.94 | 86.0 | 6.17e-01 | 96.9% | 40.2% |
| 1q14A01 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.88 | 83.0 | 5.75e-01 | 100.0% | 36.6% |
| 5ahkA02 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.75 | 65.0 | 4.62e-01 | 100.0% | 33.7% |
| 2c31A02 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.74 | 65.0 | 4.90e-01 | 100.0% | 40.3% |
| 3wdmD00 | 3.40.50.12640 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphopantoate/pantothenate synthetase | 0.74 | 66.0 | 4.37e-01 | 100.0% | 29.4% |
| 1v5eA02 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.73 | 60.0 | 4.55e-01 | 100.0% | 37.0% |
| 2nxwA02 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.72 | 62.0 | 4.70e-01 | 100.0% | 40.4% |
| 7yosA01 | 3.90.1640.30 | Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › | 0.70 | 51.0 | 3.63e-01 | 76.9% | 41.4% |
| 1zpdA02 | 3.40.50.1220 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain | 0.69 | 59.0 | 4.48e-01 | 100.0% | 39.3% |
| 3geeA03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.69 | 56.0 | 4.49e-01 | 90.8% | 51.1% |
| 1h0hA03 | 3.40.228.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2 | 0.69 | 60.0 | 3.89e-01 | 95.4% | 52.4% |
| 2p6pB01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.68 | 49.0 | 3.45e-01 | 76.9% | 23.8% |
| 1wyzA02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.67 | 48.0 | 4.08e-01 | 76.9% | 84.5% |
| 3hv8A00 | 3.20.20.450 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain | 0.67 | 54.0 | 3.78e-01 | 95.4% | 29.3% |
| 2csuA02 | 3.40.50.261 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains | 0.67 | 56.0 | 4.41e-01 | 95.4% | 47.5% |
| 1vjtA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.67 | 48.0 | 4.00e-01 | 76.9% | 56.9% |
| 1xi3A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.66 | 54.0 | 3.93e-01 | 95.4% | 32.2% |
| 3nzpB02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.66 | 56.0 | 3.73e-01 | 96.9% | 34.5% |
| 6se1A01 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.66 | 56.0 | 3.85e-01 | 100.0% | 46.0% |
| 4beqA02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.66 | 57.0 | 4.02e-01 | 100.0% | 31.3% |
| 7uuim01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.65 | 57.0 | 4.31e-01 | 98.5% | 47.5% |
| 4gj1A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.65 | 54.0 | 3.82e-01 | 96.9% | 32.3% |
| 4wqmA03 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.65 | 52.0 | 4.18e-01 | 89.2% | 48.1% |
| 3oy2A02 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.65 | 52.0 | 3.62e-01 | 96.9% | 25.4% |
| 4ldaB00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.65 | 53.0 | 4.38e-01 | 95.4% | 54.3% |
| 4u63A01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.65 | 47.0 | 3.49e-01 | 78.5% | 51.7% |
| 3knzA02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.64 | 48.0 | 3.82e-01 | 98.5% | 37.0% |
| 3otgA02 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.64 | 47.0 | 3.50e-01 | 78.5% | 32.9% |
| 2j0aA00 | 3.90.550.50 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › | 0.64 | 48.0 | 3.27e-01 | 81.5% | 21.8% |
| 4g2tA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.64 | 45.0 | 3.28e-01 | 76.9% | 24.9% |
| 4impA02 | 3.40.50.11460 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.64 | 53.0 | 3.78e-01 | 95.4% | 51.7% |
| 2yr1A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.64 | 53.0 | 3.60e-01 | 95.4% | 44.4% |
| 3tb6A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.64 | 48.0 | 3.83e-01 | 95.4% | 39.1% |
| 2qxyA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.63 | 53.0 | 4.40e-01 | 95.4% | 54.6% |
| 7bsqA01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.63 | 52.0 | 3.76e-01 | 98.5% | 66.1% |
| 4s1wB01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.63 | 49.0 | 3.56e-01 | 93.8% | 28.9% |
| 5x4kA01 | 3.90.1640.30 | Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › | 0.63 | 49.0 | 3.51e-01 | 93.8% | 29.1% |
| 4mm1C00 | 3.20.20.390 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › FMN-linked oxidoreductases | 0.62 | 51.0 | 3.60e-01 | 95.4% | 41.9% |
| 1q74B00 | 3.40.50.10320 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › LmbE-like | 0.62 | 45.0 | 3.00e-01 | 78.5% | 29.2% |
| 3oo2A02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.62 | 51.0 | 3.66e-01 | 95.4% | 31.4% |
| 3co8A02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.62 | 50.0 | 3.60e-01 | 93.8% | 31.1% |
| 4maaA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.62 | 50.0 | 3.82e-01 | 95.4% | 43.5% |
| 2amlB01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.61 | 50.0 | 3.56e-01 | 93.8% | 29.6% |
| 2gt1A01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.61 | 43.0 | 3.32e-01 | 76.9% | 33.1% |
| 4pevA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.60 | 44.0 | 3.61e-01 | 80.0% | 67.9% |
| 3tmgB01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.60 | 41.0 | 3.14e-01 | 70.8% | 85.3% |
| 3jvdB01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.60 | 43.0 | 3.54e-01 | 76.9% | 59.0% |
| 2eggB01 | 3.40.50.10860 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 | 0.60 | 44.0 | 3.42e-01 | 80.0% | 65.3% |
| 3lopA02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.59 | 48.0 | 3.86e-01 | 95.4% | 52.1% |
| 1p5hA01 | 3.40.50.10540 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Crotonobetainyl-coa:carnitine coa-transferase; domain 1 | 0.58 | 51.0 | 3.27e-01 | 100.0% | 37.0% |
| 2qu7A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 41.0 | 3.44e-01 | 78.5% | 62.8% |
| 3g85A02 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.58 | 48.0 | 3.95e-01 | 95.4% | 50.0% |
| 2ihtA03 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.57 | 44.0 | 3.19e-01 | 89.2% | 50.9% |
| 3fbtA01 | 3.40.50.10860 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 | 0.57 | 41.0 | 3.37e-01 | 81.5% | 72.1% |
| 1pdaA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 40.0 | 3.44e-01 | 76.9% | 82.6% |
| 3hs3A01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.56 | 40.0 | 3.33e-01 | 78.5% | 63.5% |
| 1zwkA00 | 3.40.50.360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain | 0.55 | 47.0 | 3.49e-01 | 95.4% | 58.0% |
| 3egcA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 39.0 | 3.24e-01 | 78.5% | 63.9% |
| 6k6wC01 | 3.40.50.10710 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Metallo-hydrolase/oxidoreductase | 0.55 | 43.0 | 3.50e-01 | 95.4% | 67.8% |
| 4wpgA02 | 3.90.25.10 | Alpha Beta › Alpha-Beta Complex › UDP-galactose 4-epimerase; domain 1 › UDP-galactose 4-epimerase, domain 1 | 0.54 | 38.0 | 3.61e-01 | 73.8% | 64.1% |
| 3uhjC01 | 3.40.50.1970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 45.0 | 3.60e-01 | 100.0% | 53.3% |
| 1zbsA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 37.0 | 3.40e-01 | 75.4% | 95.8% |
| 3jyoA01 | 3.40.50.10860 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 | 0.54 | 38.0 | 3.11e-01 | 78.5% | 74.1% |
| 2xdqA02 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.52 | 42.0 | 3.43e-01 | 93.8% | 50.0% |
| 5f4bA00 | 3.40.50.360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain | 0.52 | 41.0 | 3.23e-01 | 95.4% | 44.5% |
| 5f7vA00 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.52 | 36.0 | 2.30e-01 | 73.8% | 69.6% |
| 5bxrA01 | 3.30.379.10 | Alpha Beta › 2-Layer Sandwich › Chitobiase; domain 2 › Chitobiase/beta-hexosaminidase domain 2-like | 0.52 | 36.0 | 2.96e-01 | 78.5% | 35.8% |
| 1ixcA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.51 | 37.0 | 3.21e-01 | 76.9% | 74.0% |
| 5b3kA00 | 3.40.50.360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain | 0.51 | 40.0 | 3.24e-01 | 93.8% | 52.0% |
| 1utbB01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.51 | 37.0 | 3.01e-01 | 78.5% | 63.3% |
| 4gqoA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.50 | 43.0 | 3.13e-01 | 100.0% | 94.5% |
| 1ydgA00 | 3.40.50.360 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain | 0.50 | 41.0 | 3.07e-01 | 100.0% | 52.7% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4259946 | 2003.1.4.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 | 0.98 | 73.0 | 4.74e-01 | 76.9% | 42.6% |
| 3840042 | 2003.1.4.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 | 0.96 | 72.0 | 4.94e-01 | 78.5% | 52.6% |
| 4505851 | 375.1.1.18 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 | 0.91 | 88.0 | 5.71e-01 | 100.0% | 48.0% |
| 4936380 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.75 | 65.0 | 4.30e-01 | 95.4% | 84.8% |
| 3386810 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.74 | 63.0 | 4.17e-01 | 95.4% | 89.3% |
| 5082334 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.74 | 63.0 | 4.24e-01 | 93.8% | 91.0% |
| 3963487 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.74 | 63.0 | 4.02e-01 | 95.4% | 79.7% |
| 4301424 | 2003.1.4.8 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › CO_dh | 0.73 | 62.0 | 4.62e-01 | 96.9% | 36.9% |
| 4930548 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.72 | 62.0 | 4.20e-01 | 95.4% | 93.2% |
| 5062913 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.72 | 62.0 | 4.18e-01 | 95.4% | 91.7% |
| 4969471 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.72 | 62.0 | 4.09e-01 | 95.4% | 92.1% |
| 5007629 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.72 | 61.0 | 4.22e-01 | 95.4% | 92.9% |
| 4949240 | 2006.1.2.6 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHHA1 | 0.72 | 61.0 | 3.83e-01 | 95.4% | 63.6% |
| 5038545 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.72 | 61.0 | 4.17e-01 | 95.4% | 91.7% |
| 4940397 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.72 | 62.0 | 4.25e-01 | 96.9% | 93.3% |
| 3835401 | 2007.9.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR | 0.71 | 64.0 | 4.90e-01 | 100.0% | 52.4% |
| 4938183 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.71 | 60.0 | 4.05e-01 | 93.8% | 92.5% |
| 5010101 | 2003.1.4.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M | 0.70 | 58.0 | 4.51e-01 | 100.0% | 41.3% |
| 4034025 | 7512.1.1.8 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Epimerase_2 | 0.70 | 51.0 | 3.59e-01 | 78.5% | 26.8% |
| 3456173 | 7512.1.1.0 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase | 0.70 | 51.0 | 3.56e-01 | 80.0% | 27.1% |
| 4414950 | 2002.1.1.36 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Pterin_bind | 0.69 | 59.0 | 3.84e-01 | 98.5% | 35.2% |
| 5025765 | 2003.1.4.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M | 0.69 | 60.0 | 4.58e-01 | 100.0% | 40.6% |
| 4246433 | 2002.1.1.97 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TMP-TENI | 0.67 | 55.0 | 3.92e-01 | 95.4% | 30.4% |
| 4956242 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.67 | 56.0 | 3.88e-01 | 95.4% | 88.3% |
| 3594590 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.67 | 59.0 | 3.69e-01 | 100.0% | 21.5% |
| 4983146 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.66 | 54.0 | 3.73e-01 | 93.8% | 92.4% |
| 3231459 | 2006.1.2.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › CDC45 | 0.66 | 54.0 | 3.43e-01 | 92.3% | 91.9% |
| 5059458 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.66 | 53.0 | 3.65e-01 | 93.8% | 87.8% |
| 3744374 | 2006.1.2.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › CDC45 | 0.66 | 54.0 | 3.45e-01 | 93.8% | 94.2% |
| 3665664 | 2003.1.8.10 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › NmrA | 0.66 | 46.0 | 4.68e-01 | 75.4% | 76.9% |
| 4367083 | 7574.1.1.5 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › TPP_enzyme_C | 0.65 | 52.0 | 3.72e-01 | 89.2% | 53.2% |
| 4932675 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.65 | 52.0 | 3.63e-01 | 93.8% | 91.8% |
| 3674449 | 2003.1.2.164 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › NmrA | 0.65 | 45.0 | 4.20e-01 | 75.4% | 56.5% |
| 4572529 | 2006.1.1.2 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.65 | 54.0 | 3.92e-01 | 100.0% | 35.5% |
| 2066961 | 2002.1.1.43 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › His_biosynth | 0.65 | 54.0 | 4.50e-01 | 96.9% | 60.3% |
| 1087540 | 2007.1.3.9 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › TadZ_N | 0.65 | 53.0 | 4.37e-01 | 95.4% | 53.9% |
| 5084041 | 2002.1.1.60 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 | 0.65 | 52.0 | 3.78e-01 | 92.3% | 45.1% |
| None | — | 0.64 | 53.0 | 3.69e-01 | 95.4% | 38.3% | |
| 3949185 | 2007.1.2.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_1 | 0.64 | 47.0 | 3.79e-01 | 100.0% | 37.9% |
| 4049043 | 2002.1.1.43 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › His_biosynth | 0.64 | 53.0 | 3.66e-01 | 96.9% | 29.6% |
| 5048881 | 2004.1.1.19 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras | 0.64 | 54.0 | 4.14e-01 | 98.5% | 49.4% |
| 4928568 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.64 | 53.0 | 3.62e-01 | 95.4% | 92.2% |
| 5078492 | 2006.1.2.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases | 0.64 | 53.0 | 3.89e-01 | 95.4% | 92.4% |
| 4012072 | 7512.1.1.0 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase | 0.64 | 46.0 | 3.11e-01 | 80.0% | 19.6% |
| 5050146 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.64 | 52.0 | 3.55e-01 | 93.8% | 92.5% |
| 3476816 | 2006.1.1.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase | 0.63 | 52.0 | 3.85e-01 | 96.9% | 55.3% |
| 3175891 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.63 | 52.0 | 4.24e-01 | 95.4% | 59.2% |
| 4942298 | 2007.1.16.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 › Diphthamide_syn | 0.63 | 46.0 | 4.06e-01 | 80.0% | 52.6% |
| 3980278 | 7512.1.1.51 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_4_2 | 0.63 | 45.0 | 3.25e-01 | 76.9% | 27.2% |
| 3910192 | 2006.1.2.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › CDC45 | 0.63 | 50.0 | 3.20e-01 | 90.8% | 94.2% |
| 3231322 | 2006.1.6.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like | 0.62 | 51.0 | 3.70e-01 | 95.4% | 55.6% |
| 3631208 | 2006.1.1.2 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.62 | 52.0 | 3.80e-01 | 100.0% | 37.5% |
| 5032111 | 2006.1.2.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH | 0.61 | 49.0 | 3.44e-01 | 96.9% | 90.0% |
| 5030434 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.61 | 51.0 | 3.88e-01 | 96.9% | 49.7% |
| 165362 | 2007.1.3.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg | 0.61 | 50.0 | 4.21e-01 | 95.4% | 55.1% |
| 3940849 | 7516.1.1.12 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Fringe | 0.61 | 44.0 | 2.96e-01 | 78.5% | 18.5% |
| 4947102 | 2006.1.2.8 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH_CID | 0.61 | 48.0 | 3.38e-01 | 95.4% | 89.2% |
| 5060484 | 2007.1.5.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like | 0.60 | 43.0 | 3.33e-01 | 76.9% | 60.0% |
| 3396851 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.60 | 50.0 | 3.71e-01 | 98.5% | 40.0% |
| 4438574 | 7512.1.1.10 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_28 | 0.60 | 51.0 | 3.73e-01 | 100.0% | 43.7% |
| 4952090 | 7512.1.1.3 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 | 0.59 | 51.0 | 3.79e-01 | 100.0% | 80.0% |
| 5055504 | 7512.1.1.3 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 | 0.59 | 49.0 | 3.57e-01 | 98.5% | 40.0% |
| 3263272 | 2484.1.1.66 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 | 0.59 | 42.0 | 3.34e-01 | 76.9% | 45.0% |
| 11185 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.58 | 40.0 | 3.51e-01 | 73.8% | 86.0% |
| 3971172 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.58 | 46.0 | 3.43e-01 | 95.4% | 31.5% |
| 3170000 | 2004.1.1.103 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Sua5_C | 0.58 | 41.0 | 3.30e-01 | 75.4% | 37.8% |
| 3822531 | 7579.1.1.16 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Palm_thioest | 0.57 | 46.0 | 3.19e-01 | 100.0% | 68.9% |
| 5055004 | 2007.1.7.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › Fe-ADH | 0.56 | 46.0 | 3.49e-01 | 95.4% | 61.7% |
| 5047031 | 7512.1.1.3 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 | 0.56 | 46.0 | 3.41e-01 | 98.5% | 45.6% |
| 5049241 | 7514.1.1.1 ↗ | a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 | 0.55 | 46.0 | 3.73e-01 | 95.4% | 54.8% |
| 3224227 | 2007.1.2.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I | 0.55 | 45.0 | 3.07e-01 | 95.4% | 23.8% |
| 3587108 | 2005.1.1.72 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › PF30635 | 0.55 | 40.0 | 3.31e-01 | 83.1% | 70.7% |
| 5046011 | 7581.1.1.15 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_C_1 | 0.55 | 41.0 | 2.58e-01 | 80.0% | 15.2% |
| 3277978 | 2498.2.1.1 ↗ | mixed a+b and a/b › Zincin-like › beta-N-acetylhexosaminidase-like domain › beta-N-acetylhexosaminidase-like domain › Glyco_hydro_20b | 0.52 | 35.0 | 2.95e-01 | 80.0% | 35.4% |
| 3280738 | 2007.1.4.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain | 0.52 | 40.0 | 3.71e-01 | 100.0% | 64.2% |
| 3951052 | 7523.1.1.8 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_1 | 0.51 | 42.0 | 3.05e-01 | 95.4% | 64.4% |
| 4525578 | 2007.2.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 | 0.51 | 41.0 | 3.11e-01 | 100.0% | 51.0% |
| 3966388 | 2007.2.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins | 0.51 | 40.0 | 3.23e-01 | 93.8% | 56.0% |
D2
medium
residues 30-84
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02146.24 best | SIR2 | 40.3 | 4.80e-10 | 100.0% | 28.3% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1q1aA02 | 3.30.1600.10 | Alpha Beta › 2-Layer Sandwich › SIR2/SIRT2 'Small Domain' › SIR2/SIRT2 'Small Domain' | 0.83 | 73.0 | 5.77e-01 | 100.0% | 48.6% |
| 2d27A02 | 3.30.300.160 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Type II secretion system, protein E, N-terminal domain | 0.57 | 43.0 | 3.71e-01 | 81.8% | 62.4% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4505851 | 375.1.1.18 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SIR2 | 0.92 | 78.0 | 4.96e-01 | 100.0% | 21.4% |
| 4174345 | 2003.1.4.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 | 0.90 | 81.0 | 5.19e-01 | 100.0% | 23.6% |
| 4034215 | 2003.1.4.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 | 0.88 | 79.0 | 5.01e-01 | 100.0% | 21.8% |
| 3707610 | 2003.1.4.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 | 0.82 | 75.0 | 4.57e-01 | 100.0% | 18.4% |
| 4946013 | 2003.1.4.5 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2 | 0.66 | 55.0 | 3.69e-01 | 94.5% | 39.7% |