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Filtrate_w_scaffold_3_prodigal-single.1__X__X__00423
Bact-VirFiltrate_w_scaffold_3_prodigal-single.1__X__X__00423
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 54-132_207-315
D2
medium
residues 133-206
D3
medium
residues 316-334_390-438
D4
medium
residues 500-590_608-628_774-824
Domain cluster:
representative
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.75 | 36.0 | 4.34e-01 | 95.1% | 66.4% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.74 | 36.0 | 4.25e-01 | 95.1% | 64.4% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.69 | 36.0 | 3.96e-01 | 95.1% | 60.2% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 40.0 | 4.45e-01 | 98.2% | 70.9% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.66 | 34.0 | 3.97e-01 | 93.3% | 68.4% |
| 2uxwA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 38.0 | 4.19e-01 | 94.5% | 73.8% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 35.0 | 3.95e-01 | 94.5% | 69.5% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 39.0 | 3.84e-01 | 83.4% | 59.5% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.57 | 40.0 | 3.82e-01 | 94.5% | 61.8% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 40.0 | 4.10e-01 | 77.3% | 73.0% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 38.0 | 4.04e-01 | 76.1% | 79.1% |
| 4im0A04 | 1.20.1270.420 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 42.0 | 3.72e-01 | 77.9% | 76.1% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.56 | 42.0 | 3.99e-01 | 79.1% | 65.1% |
| 1qu7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.55 | 41.0 | 3.68e-01 | 76.7% | 67.0% |
| 3kkdA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 34.0 | 3.25e-01 | 83.4% | 50.0% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 39.0 | 3.51e-01 | 76.7% | 49.8% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 39.0 | 3.92e-01 | 79.1% | 72.0% |
| 1yc9A01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.55 | 44.0 | 3.54e-01 | 86.5% | 42.8% |
| 2m6bA00 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.54 | 34.0 | 3.56e-01 | 100.0% | 66.7% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.54 | 43.0 | 3.91e-01 | 84.7% | 97.7% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.54 | 40.0 | 3.29e-01 | 77.3% | 42.1% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 38.0 | 3.41e-01 | 74.2% | 51.7% |
| 2hydA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.53 | 40.0 | 3.27e-01 | 99.4% | 39.9% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 37.0 | 3.38e-01 | 79.8% | 55.3% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.51 | 38.0 | 4.06e-01 | 99.4% | 87.4% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.51 | 35.0 | 3.73e-01 | 81.0% | 78.1% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 46.0 | 4.09e-01 | 99.4% | 75.9% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.50 | 37.0 | 3.80e-01 | 76.7% | 81.4% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.50 | 40.0 | 3.18e-01 | 98.2% | 41.8% |
ECOD (43)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3766796 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.64 | 38.0 | 4.14e-01 | 97.5% | 67.9% |
| 4025710 | 3871.1.1.0 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST | 0.61 | 38.0 | 4.21e-01 | 90.8% | 79.2% |
| 4980098 | 3834.1.1.0 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain | 0.60 | 44.0 | 3.81e-01 | 77.3% | 89.4% |
| 3562523 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.56 | 40.0 | 3.94e-01 | 79.1% | 67.6% |
| 4775818 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 40.0 | 3.81e-01 | 73.6% | 64.2% |
| 3289986 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.55 | 39.0 | 4.09e-01 | 76.7% | 79.3% |
| 3239791 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 36.0 | 3.55e-01 | 84.0% | 60.0% |
| 3699472 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 48.0 | 3.42e-01 | 96.3% | 47.1% |
| 3368865 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 40.0 | 3.84e-01 | 74.8% | 74.5% |
| 4520297 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.54 | 43.0 | 3.82e-01 | 85.3% | 86.9% |
| 3346133 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 39.0 | 3.59e-01 | 74.2% | 73.0% |
| 3942242 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.54 | 42.0 | 4.48e-01 | 81.6% | 99.3% |
| 3369676 | 603.2.1.13 ↗ | alpha bundles › STAT-like › STAT › STAT › NET2A_C | 0.54 | 41.0 | 4.04e-01 | 81.6% | 71.7% |
| 3770066 | 3291.1.1.169 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF21A_4th | 0.54 | 37.0 | 3.55e-01 | 74.2% | 58.5% |
| 3987659 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 35.0 | 3.23e-01 | 73.0% | 48.8% |
| 4992667 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 38.0 | 3.21e-01 | 77.9% | 42.2% |
| 5002102 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 39.0 | 3.94e-01 | 78.5% | 73.5% |
| 3182497 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.53 | 31.0 | 2.30e-01 | 98.8% | 20.9% |
| 3696555 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.53 | 40.0 | 3.84e-01 | 82.8% | 68.6% |
| 3838987 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 36.0 | 3.42e-01 | 75.5% | 56.0% |
| 4944766 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 38.0 | 3.60e-01 | 84.7% | 60.0% |
| 4021462 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 41.0 | 2.89e-01 | 82.2% | 84.2% |
| 3381175 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.53 | 38.0 | 3.38e-01 | 74.2% | 77.1% |
| 3377464 | 3755.3.1.285 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A | 0.53 | 37.0 | 3.79e-01 | 71.8% | 98.1% |
| 3611166 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 38.0 | 3.60e-01 | 78.5% | 61.0% |
| 4984240 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.52 | 38.0 | 2.62e-01 | 77.9% | 21.1% |
| 5020818 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 38.0 | 2.77e-01 | 76.7% | 25.6% |
| 3889547 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 38.0 | 3.63e-01 | 77.9% | 63.7% |
| 4031283 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 36.0 | 3.80e-01 | 77.9% | 77.3% |
| 5054860 | 3755.3.1.305 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook | 0.52 | 38.0 | 3.71e-01 | 82.2% | 67.0% |
| 3574610 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.52 | 41.0 | 3.84e-01 | 82.8% | 85.5% |
| 3908132 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 39.0 | 3.39e-01 | 77.3% | 87.8% |
| 4456477 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 39.0 | 3.80e-01 | 100.0% | 72.0% |
| 5054861 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.52 | 39.0 | 2.83e-01 | 77.3% | 79.1% |
| 3239971 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.52 | 38.0 | 3.39e-01 | 74.8% | 73.9% |
| 5025381 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.51 | 36.0 | 2.90e-01 | 79.8% | 35.8% |
| 3268736 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.51 | 38.0 | 2.69e-01 | 75.5% | 77.8% |
| 5002671 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.51 | 37.0 | 3.73e-01 | 77.9% | 75.0% |
| 3675237 | 4177.2.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain | 0.50 | 39.0 | 3.37e-01 | 81.6% | 80.8% |
| 4001186 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.50 | 38.0 | 3.69e-01 | 80.4% | 80.5% |
| 4400687 | 2004.1.1.782 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23, AAA_29, SbcC_Walker_B | 0.50 | 35.0 | 2.59e-01 | 82.8% | 25.9% |
| 3592441 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.50 | 37.0 | 3.74e-01 | 100.0% | 77.5% |
| 5024408 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.50 | 38.0 | 3.69e-01 | 79.8% | 86.5% |
D5
medium
residues 591-607_825-902
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7f16R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 47.0 | 3.34e-01 | 72.6% | 83.0% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4940986 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.71 | 51.0 | 5.17e-01 | 74.7% | 88.4% |
| 3720522 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.60 | 45.0 | 3.25e-01 | 78.9% | 61.9% |
| 3723668 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 38.0 | 3.32e-01 | 77.9% | 50.3% |
D6
medium
residues 629-773
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2p0tA02 | 1.10.60.30 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › PSPTO4464-like domains | 0.52 | 21.0 | 2.74e-01 | 84.8% | 63.9% |