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Formamidopyrimidine-DNA_glycosylase
Euk-VirAcanthamoeba_polyphaga_moumouvirus
Formamidopyrimidine-DNA_glycosylase__YP_007354485__Acanthamoeba_polyphaga_moumouvirus__1269028
Identity
- Accession:
- YP_007354485 ↗
- Protein ID:
- Formamidopyrimidine-DNA_glycosylase
- Kingdom:
- euk
Quality
79.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Moumouvirus›
Acanthamoeba_polyphaga_moumouvirus
TaxID: 1269028
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-131
Domain cluster:
rep: S2_005_003_R2_scaffold_7_prodigal-single.1__X__X__00412__D4-111
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01149.30 best | Fapy_DNA_glyco | 47.6 | 3.50e-12 | 88.4% | 97.4% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3a46A01 | 3.20.190.10 | Alpha Beta › Alpha-Beta Barrel › N-terminal domain of MutM-like DNA repair proteins › MutM-like, N-terminal | 0.86 | 83.0 | 8.13e-01 | 100.0% | 97.1% |
| 3twlA01 | 3.20.190.10 | Alpha Beta › Alpha-Beta Barrel › N-terminal domain of MutM-like DNA repair proteins › MutM-like, N-terminal | 0.77 | 71.0 | 7.20e-01 | 100.0% | 99.2% |
| 1nnjA01 | 3.20.190.10 | Alpha Beta › Alpha-Beta Barrel › N-terminal domain of MutM-like DNA repair proteins › MutM-like, N-terminal | 0.75 | 71.0 | 7.07e-01 | 100.0% | 97.7% |
| 4mb7A01 | 3.20.190.10 | Alpha Beta › Alpha-Beta Barrel › N-terminal domain of MutM-like DNA repair proteins › MutM-like, N-terminal | 0.73 | 65.0 | 6.59e-01 | 100.0% | 96.0% |
| 3eb8B01 | 3.10.450.460 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › EspG protein, N-terminal domain | 0.71 | 28.0 | 4.05e-01 | 85.3% | 77.0% |
| 3w0fA01 | 3.20.190.10 | Alpha Beta › Alpha-Beta Barrel › N-terminal domain of MutM-like DNA repair proteins › MutM-like, N-terminal | 0.71 | 62.0 | 6.45e-01 | 98.4% | 99.2% |
| 4r80A00 | 3.10.450.630 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.63 | 36.0 | 4.61e-01 | 92.2% | 96.1% |
| 2xepB01 | 3.10.450.280 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.60 | 45.0 | 4.83e-01 | 89.9% | 89.5% |
| 3ovcA01 | 3.30.200.150 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › | 0.59 | 33.0 | 4.24e-01 | 88.4% | 98.6% |
| 3u1wA01 | 3.10.450.360 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.59 | 35.0 | 3.14e-01 | 96.1% | 42.1% |
| 2kd2A01 | 2.40.128.180 | Mainly Beta › Beta Barrel › Lipocalin › | 0.58 | 35.0 | 4.26e-01 | 76.7% | 92.9% |
| 5cfvA01 | 3.30.700.10 | Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › Glycoprotein, Type 4 Pilin | 0.56 | 33.0 | 3.63e-01 | 93.8% | 70.1% |
| 6hpvA01 | 3.10.450.10 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 35.0 | 4.25e-01 | 88.4% | 98.8% |
| 8ainB01 | 3.10.450.250 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › S. aureus uracil DNA glycosylase inhibitor | 0.54 | 37.0 | 4.03e-01 | 100.0% | 84.8% |
| 2p4bB02 | 3.30.200.100 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › MucB/RseB, C-terminal domain | 0.54 | 34.0 | 3.86e-01 | 85.3% | 83.7% |
| 4aghA00 | 2.30.31.10 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A | 0.53 | 29.0 | 3.55e-01 | 93.0% | 83.7% |
| 6w0pB01 | 2.70.98.40 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain | 0.53 | 42.0 | 3.28e-01 | 84.5% | 65.4% |
| 3mswA00 | 2.40.128.720 | Mainly Beta › Beta Barrel › Lipocalin › | 0.52 | 33.0 | 3.22e-01 | 93.8% | 58.3% |
| 2wb8A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.52 | 36.0 | 3.39e-01 | 71.3% | 91.9% |
| 3w9kA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 35.0 | 3.46e-01 | 92.2% | 65.2% |
| 3fo5B00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.51 | 37.0 | 3.03e-01 | 73.6% | 79.0% |
| 5gv0A00 | 2.40.160.110 | Mainly Beta › Beta Barrel › Porin › | 0.51 | 36.0 | 3.39e-01 | 92.2% | 58.6% |
| 2bhzA04 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.50 | 28.0 | 3.78e-01 | 78.3% | 100.0% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 145646 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.86 | 83.0 | 8.19e-01 | 100.0% | 99.2% |
| 4033403 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.78 | 74.0 | 6.98e-01 | 100.0% | 99.3% |
| 3789023 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.78 | 74.0 | 6.88e-01 | 100.0% | 98.7% |
| 3856809 | 4099.1.1.0 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like | 0.77 | 40.0 | 4.76e-01 | 92.2% | 73.3% |
| 4291331 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.76 | 72.0 | 7.10e-01 | 100.0% | 97.0% |
| 4945708 | 3504.2.1.2 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › H2TH | 0.76 | 72.0 | 7.10e-01 | 100.0% | 98.5% |
| 4350188 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.76 | 71.0 | 6.52e-01 | 100.0% | 98.8% |
| 4422963 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.75 | 71.0 | 6.61e-01 | 100.0% | 99.4% |
| 4186554 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.75 | 70.0 | 6.96e-01 | 100.0% | 98.5% |
| 4202644 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.75 | 70.0 | 7.06e-01 | 100.0% | 99.2% |
| 5074040 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.75 | 70.0 | 7.00e-01 | 100.0% | 98.5% |
| 4071792 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.75 | 70.0 | 6.93e-01 | 100.0% | 97.8% |
| 4457982 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.75 | 69.0 | 6.91e-01 | 97.7% | 99.2% |
| 4424253 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.74 | 69.0 | 6.66e-01 | 100.0% | 99.3% |
| 4978702 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.74 | 70.0 | 6.98e-01 | 100.0% | 100.0% |
| 4958140 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.74 | 69.0 | 6.97e-01 | 100.0% | 99.2% |
| 4544218 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.73 | 67.0 | 6.70e-01 | 97.7% | 100.0% |
| 5050803 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.73 | 68.0 | 6.82e-01 | 100.0% | 99.2% |
| 5032907 | 3504.2.1.0 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins | 0.73 | 68.0 | 6.78e-01 | 99.2% | 98.5% |
| 3885183 | 3504.2.1.1 ↗ | beta barrels › MutM N-terminal domain-like › N-terminal domain of MutM-like DNA repair proteins › N-terminal domain of MutM-like DNA repair proteins › Fapy_DNA_glyco | 0.70 | 64.0 | 6.43e-01 | 100.0% | 96.9% |
| 3962450 | 9.27.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › LpqH › LpqH | 0.67 | 32.0 | 3.58e-01 | 78.3% | 57.1% |
| 5014253 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.67 | 34.0 | 4.51e-01 | 89.9% | 90.0% |
| 4228206 | 708.1.1.0 ↗ | beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain | 0.66 | 34.0 | 4.18e-01 | 87.6% | 77.5% |
| 5014686 | 809.2.1.0 ↗ | a+b two layers › BLIP-like › BT0923-like › BT0923-like | 0.66 | 29.0 | 4.31e-01 | 87.6% | 98.2% |
| 4028363 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.60 | 39.0 | 4.51e-01 | 93.0% | 93.3% |
| 3956703 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.60 | 45.0 | 4.81e-01 | 92.2% | 91.8% |
| 3725227 | 519.1.1.1 ↗ | a+b two layers › mRNA decapping enzyme DcpS N-terminal domain › mRNA decapping enzyme DcpS N-terminal domain › mRNA decapping enzyme DcpS N-terminal domain › DcpS | 0.57 | 35.0 | 4.26e-01 | 72.9% | 100.0% |
| 3979569 | 9.1.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins | 0.56 | 29.0 | 3.18e-01 | 89.9% | 57.3% |
| 5004871 | 331.4.1.0 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 | 0.55 | 30.0 | 3.51e-01 | 72.9% | 75.6% |
| 3619927 | 9.2.1.6 ↗ | beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › DUF7042 | 0.55 | 40.0 | 4.23e-01 | 87.6% | 84.3% |
| 4970968 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.55 | 33.0 | 3.51e-01 | 72.9% | 68.1% |
| 3417002 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.54 | 39.0 | 4.12e-01 | 94.6% | 80.8% |
| 5040587 | 331.3.1.11 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 | 0.54 | 39.0 | 3.72e-01 | 92.2% | 63.2% |
| 4001579 | 9.1.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins | 0.53 | 40.0 | 4.18e-01 | 86.8% | 86.1% |
| 3969438 | 9.1.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins | 0.53 | 35.0 | 3.95e-01 | 77.5% | 86.0% |
| 3802399 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.53 | 38.0 | 3.93e-01 | 92.2% | 77.6% |
| 3940934 | 4023.1.1.0 ↗ | a+b two layers › N-terminal a+b domain in DNA primase core › N-terminal a+b domain in DNA primase core › N-terminal a+b domain in DNA primase core | 0.52 | 28.0 | 3.27e-01 | 89.9% | 70.5% |
| 3957060 | 325.1.6.2 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Duplicated hybrid motif › Peptidase_M23 | 0.51 | 38.0 | 3.68e-01 | 78.3% | 80.0% |
| 3742937 | 519.1.1.1 ↗ | a+b two layers › mRNA decapping enzyme DcpS N-terminal domain › mRNA decapping enzyme DcpS N-terminal domain › mRNA decapping enzyme DcpS N-terminal domain › DcpS | 0.50 | 35.0 | 3.86e-01 | 72.1% | 100.0% |
D2
high
residues 145-215_239-278
Domain cluster:
rep: AB605730.1__BAK52944.1__X__00132__D130-268
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06831.20 best | H2TH | 46.0 | 6.00e-12 | 70.3% | 69.9% |
| PF21025.3 | Fapy_DNA_glyco_C | 89.5 | 1.40e-25 | 38.7% | 83.7% |