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GIY-YIG_endonuclease_superfamily_protein

Euk-Vir

Chrysochromulina_ericina_virus

GIY-YIG_endonuclease_superfamily_protein__YP_009173403__Chrysochromulina_ericina_virus__455364

Identity

Accession:
YP_009173403 ↗
Protein ID:
GIY-YIG_endonuclease_superfamily_protein
Kingdom:
euk

Quality

76.4 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Algavirales› Phycodnaviridae› Chrysochromulina_ericina_virus

TaxID: 455364

Cluster

View cluster (28 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-59
PDB
Domain cluster: rep: H2c1_full_idba_ud_scaffold_88_prodigal-single.1__X__X__00452__D3-76
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01541.31 best GIY-YIG 43.3 5.00e-11 100.0% 65.4%
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7bjkA02 3.55.40.20 Alpha Beta › 3-Layer(bab) Sandwich › minor pseudopilin epsh fold › Iron/manganese superoxide dismutase, C-terminal domain 0.72 47.0 3.74e-01 100.0% 34.5%
2pstX00 3.90.820.10 Alpha Beta › Alpha-Beta Complex › Rubredoxin-like › Structural Genomics, Unknown Function 30-nov-00 1gh9 Mol_id 0.71 42.0 4.22e-01 96.6% 57.4%
5fljA00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.71 46.0 3.17e-01 100.0% 21.4%
4gi3C00 3.30.60.30 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › 0.70 45.0 4.64e-01 93.2% 68.4%
3ir9A02 3.30.1330.30 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 0.67 50.0 3.99e-01 100.0% 40.0%
3zoqC00 6.20.250.30 Special › Other non-globular › Double Stranded RNA Binding Domain › 0.66 50.0 5.22e-01 100.0% 92.5%
3l5iA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 45.0 4.05e-01 100.0% 52.3%
1ywlA00 3.40.1440.10 Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease 0.63 53.0 4.55e-01 100.0% 58.3%
2cuhA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 45.0 4.05e-01 100.0% 52.3%
5mj6A03 2.60.40.1910 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 46.0 4.20e-01 100.0% 58.7%
3pjyA00 2.60.120.1140 Mainly Beta › Sandwich › Jelly Rolls › Protein of unknown function DUF192 0.62 51.0 4.04e-01 93.2% 96.9%
3fl7A05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 43.0 3.91e-01 100.0% 51.2%
6m3yA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 47.0 3.78e-01 100.0% 41.7%
3i6sA03 3.50.30.30 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › 0.62 53.0 4.16e-01 98.3% 100.0%
3rj2X00 2.60.120.1150 Mainly Beta › Sandwich › Jelly Rolls › 0.62 46.0 3.51e-01 100.0% 35.3%
2ovsA00 2.40.128.380 Mainly Beta › Beta Barrel › Lipocalin › T3SS negative regulator GrlR 0.62 54.0 4.36e-01 100.0% 87.3%
7y8sB03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 44.0 4.03e-01 100.0% 56.0%
6gszA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 48.0 4.09e-01 100.0% 51.0%
1nc7A00 2.60.290.11 Mainly Beta › Sandwich › Hypothetical Protein Tm1070; Chain: A › TM1070-like 0.61 46.0 3.76e-01 100.0% 43.1%
1cyyA02 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.60 52.0 4.15e-01 100.0% 95.2%
3mfiA04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.60 52.0 4.19e-01 100.0% 54.6%
4u7cB04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.59 52.0 4.27e-01 100.0% 56.9%
3h20A01 3.30.1490.240 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain 0.59 44.0 4.35e-01 100.0% 75.8%
1i7dA03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.59 51.0 3.93e-01 100.0% 92.9%
1ylnA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.58 51.0 4.10e-01 100.0% 50.9%
3loiA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.57 42.0 3.10e-01 100.0% 29.4%
4iajA00 3.30.1490.390 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Protein of unknown function DUF4649 0.57 44.0 4.04e-01 100.0% 64.5%
2f4nB02 2.40.30.90 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Bacterial fluorinating enzyme like 0.57 48.0 4.17e-01 94.9% 70.2%
4bq2D01 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.57 47.0 3.42e-01 98.3% 47.6%
1unnC00 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.57 46.0 3.88e-01 100.0% 51.4%
7ejoB01 3.30.2260.10 Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary 0.57 48.0 4.35e-01 96.6% 74.7%
1xvsA00 2.60.40.1470 Mainly Beta › Sandwich › Immunoglobulin-like › ApaG domain 0.56 48.0 3.78e-01 100.0% 45.5%
4kncA02 2.60.120.1380 Mainly Beta › Sandwich › Jelly Rolls › C-terminal carbohydrate-binding module 0.56 47.0 3.80e-01 98.3% 47.9%
2fr5A00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.56 47.0 3.64e-01 100.0% 41.2%
6julA02 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.56 47.0 4.06e-01 100.0% 59.4%
5z6pA01 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.56 45.0 3.38e-01 98.3% 49.4%
3f6zB01 2.40.128.200 Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor 0.55 45.0 4.10e-01 89.8% 97.5%
1jx4A04 3.30.1490.100 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain 0.55 46.0 4.00e-01 100.0% 59.2%
3dshA01 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.55 47.0 3.33e-01 100.0% 86.6%
1vl7A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.55 45.0 3.51e-01 100.0% 40.7%
1xe7A00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.54 41.0 2.93e-01 98.3% 26.3%
2yvsA01 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.54 42.0 3.41e-01 100.0% 44.7%
1qysA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.53 40.0 3.58e-01 100.0% 55.4%
3h8hA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.53 44.0 3.87e-01 94.9% 95.7%
6z9cA01 2.60.40.1470 Mainly Beta › Sandwich › Immunoglobulin-like › ApaG domain 0.53 46.0 3.63e-01 100.0% 47.5%
2i51B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.53 44.0 3.16e-01 100.0% 30.4%
4nx9A02 2.60.40.4390 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 45.0 3.64e-01 100.0% 65.3%
2pwyA01 3.10.330.20 Alpha Beta › Roll › Vcp-like ATPase; Chain A, domain 2 › 0.52 42.0 4.33e-01 89.8% 100.0%
7bysA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.52 43.0 3.46e-01 98.3% 45.9%
5x7qA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.52 43.0 3.42e-01 98.3% 44.1%
2f1eA00 2.60.40.1470 Mainly Beta › Sandwich › Immunoglobulin-like › ApaG domain 0.51 44.0 3.54e-01 100.0% 49.1%
4avaA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.51 37.0 2.90e-01 100.0% 32.6%
1u3eM02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 44.0 4.20e-01 100.0% 82.4%
2lc1A00 2.60.200.20 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.51 42.0 3.70e-01 100.0% 94.0%
3a21A03 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.51 43.0 3.69e-01 100.0% 77.2%
2wq4A01 2.60.120.760 Mainly Beta › Sandwich › Jelly Rolls › 0.51 43.0 3.39e-01 96.6% 74.4%
2v5mA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 39.0 3.34e-01 93.2% 50.0%
2jz6A01 2.30.170.40 Mainly Beta › Roll › Ribosomal Protein L24e; Chain: T; › Ribosomal protein L28/L24 0.51 32.0 3.43e-01 98.3% 74.0%
4wiwA02 3.10.50.10 Alpha Beta › Roll › Chitinase A; domain 3 › 0.50 40.0 3.83e-01 89.8% 100.0%
1et9A01 3.10.20.120 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.50 42.0 3.53e-01 100.0% 88.2%
ECOD (54)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4623707 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.86 71.0 5.94e-01 100.0% 54.7%
4158495 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.85 70.0 5.96e-01 98.3% 57.8%
3942510 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.84 70.0 5.87e-01 100.0% 55.8%
4997210 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.81 68.0 5.81e-01 100.0% 58.9%
4397568 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.81 68.0 5.81e-01 100.0% 58.9%
5046850 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.81 69.0 5.94e-01 100.0% 61.1%
4557537 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.81 67.0 5.76e-01 100.0% 58.9%
3971569 821.1.1.0 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease 0.81 67.0 5.87e-01 100.0% 62.4%
4669741 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.80 67.0 5.63e-01 100.0% 55.8%
5065792 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.78 63.0 4.57e-01 100.0% 33.5%
3624434 821.1.1.8 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › ANKLE2_3rd 0.73 62.0 4.30e-01 100.0% 29.7%
3968122 3115.6.1.2 ↗ a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597 0.72 51.0 5.75e-01 100.0% 97.8%
5034902 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.71 57.0 4.22e-01 100.0% 35.2%
3969006 3115.6.1.2 ↗ a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597 0.70 51.0 5.66e-01 100.0% 100.0%
4004704 3115.6.1.2 ↗ a+b two layers › GP2-like › Bacterial RNA polymerase subunit epsilon › Bacterial RNA polymerase subunit epsilon › PF28597 0.69 50.0 5.56e-01 100.0% 100.0%
3861730 11.1.1.2 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.69 47.0 4.19e-01 100.0% 47.8%
5028854 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.69 53.0 4.02e-01 100.0% 35.3%
1568615 11.1.1.315 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › MalQ_N 0.69 47.0 4.21e-01 98.3% 50.0%
4463006 3115.2.1.0 ↗ a+b two layers › GP2-like › GP2 › GP2 0.67 48.0 5.29e-01 94.9% 97.8%
3561485 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.67 45.0 4.07e-01 100.0% 49.4%
3512155 560.1.1.3 ↗ few secondary structure elements › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain › H-NS histone-like proteins, C-terminal domain › DUF5648 0.64 44.0 3.74e-01 100.0% 44.2%
1003912 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.63 53.0 4.55e-01 100.0% 58.3%
5015713 3115.1.1.0 ↗ a+b two layers › GP2-like › RplX-like › RplX-like 0.63 55.0 5.47e-01 96.6% 98.3%
3403086 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 47.0 3.95e-01 100.0% 48.0%
3888326 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 43.0 3.77e-01 100.0% 45.0%
3573883 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.62 55.0 4.32e-01 100.0% 49.6%
3680204 228.1.1.1 ↗ a+b three layers › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Sod_Fe_C 0.61 52.0 4.04e-01 100.0% 44.1%
3933380 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.61 54.0 4.35e-01 100.0% 51.3%
3590261 822.3.1.1 ↗ a+b two layers › GYF/BRK domain-like › conserved domain protein SP_1775 › conserved domain protein SP_1775 › DUF4649 0.60 46.0 4.41e-01 98.3% 72.1%
3365003 11.1.4.55 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › Self-incomp_S1 0.60 45.0 3.80e-01 100.0% 46.7%
3905386 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 41.0 3.98e-01 100.0% 62.9%
4644368 11.1.4.120 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › PF30318 0.60 42.0 3.57e-01 100.0% 42.9%
3812151 11.1.4.55 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › Self-incomp_S1 0.59 43.0 3.59e-01 98.3% 42.7%
3194295 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.59 52.0 4.09e-01 100.0% 48.0%
3478944 821.1.1.0 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease 0.59 50.0 4.23e-01 98.3% 70.5%
3987692 822.3.1.1 ↗ a+b two layers › GYF/BRK domain-like › conserved domain protein SP_1775 › conserved domain protein SP_1775 › DUF4649 0.58 43.0 4.10e-01 100.0% 68.6%
3221194 10.32.1.68 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Glce_b_sandwich 0.57 50.0 3.52e-01 100.0% 59.0%
5075125 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 42.0 3.56e-01 98.3% 48.0%
4011217 304.57.1.0 ↗ a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.56 49.0 3.97e-01 100.0% 87.8%
4083103 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.55 47.0 3.78e-01 100.0% 47.2%
4229796 11.1.1.67 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF525 0.55 46.0 3.64e-01 100.0% 44.8%
4450183 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.55 46.0 3.79e-01 100.0% 50.4%
3965278 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.54 45.0 3.79e-01 100.0% 53.6%
4204424 302.1.1.1 ↗ a+b two layers › Reverse ferredoxin › Lesion bypass DNA polymerase (Y-family), little finger domain › Lesion bypass DNA polymerase (Y-family), little finger domain › IMS_C 0.53 45.0 3.78e-01 100.0% 55.2%
5019286 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.53 45.0 3.83e-01 98.3% 71.0%
3404656 11.1.1.884 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Metallopep 0.52 42.0 3.61e-01 98.3% 54.0%
3603549 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.52 43.0 4.06e-01 100.0% 78.2%
3881492 109.4.1.411 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TTC3_DZIP3_dom 0.52 43.0 2.79e-01 96.6% 19.0%
3972526 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.52 41.0 4.01e-01 98.3% 97.1%
3615149 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 42.0 2.78e-01 100.0% 31.4%
4025385 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.51 43.0 3.10e-01 94.9% 36.1%
3567698 11.1.1.127 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › IL6Ra-bind 0.51 39.0 3.36e-01 100.0% 49.5%
4932670 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.51 42.0 3.67e-01 98.3% 58.9%
4870707 4121.1.1.2 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › MRS2-like 0.51 45.0 2.94e-01 96.6% 30.6%
D2 medium residues 60-125
PDB
Domain cluster: representative
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1j78A05 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.85 56.0 5.89e-01 71.2% 75.0%
1n5uA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.82 54.0 4.57e-01 75.8% 43.7%
5oklA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.80 54.0 4.60e-01 75.8% 45.5%
2x4hA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.78 55.0 4.30e-01 72.7% 45.0%
1cvuA02 1.10.640.10 Mainly Alpha › Orthogonal Bundle › Myeloperoxidase, subunit C › Haem peroxidase domain superfamily, animal type 0.77 64.0 3.71e-01 87.9% 35.8%
3b0cW00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.74 53.0 5.11e-01 80.3% 67.1%
3d5lA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.74 50.0 5.53e-01 98.5% 90.4%
1uyvB02 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.73 52.0 3.35e-01 74.2% 21.3%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.73 62.0 4.69e-01 90.9% 47.6%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.73 61.0 4.66e-01 90.9% 56.2%
3ermB00 1.10.10.710 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like 0.71 50.0 5.11e-01 74.2% 78.1%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.70 48.0 4.47e-01 72.7% 58.1%
4ixjA01 3.30.1300.80 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.69 58.0 5.47e-01 97.0% 76.6%
6fakA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.69 45.0 4.00e-01 75.8% 46.3%
1ad6A00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.67 58.0 4.29e-01 100.0% 48.6%
1sg7A00 1.10.1740.70 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › ChaB 0.66 51.0 4.92e-01 90.9% 74.7%
2no4A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.66 54.0 5.23e-01 100.0% 80.0%
2pusA05 1.10.1740.80 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.66 43.0 4.06e-01 89.4% 55.0%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.65 53.0 3.50e-01 89.4% 92.0%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.64 49.0 4.63e-01 86.4% 69.2%
2j82A00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.64 55.0 3.87e-01 100.0% 54.3%
153lA00 1.10.530.10 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.64 59.0 4.15e-01 100.0% 38.9%
3g36B00 1.20.890.10 Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 0.62 43.0 4.69e-01 74.2% 98.0%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.60 47.0 3.44e-01 84.8% 31.8%
3vm9A02 6.10.140.2110 Special › Helix non-globular › Helix Hairpins › 0.60 43.0 4.57e-01 84.8% 89.5%
1hwyA01 1.10.287.140 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 40.0 4.39e-01 80.3% 94.1%
4mi2A02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.58 39.0 4.15e-01 83.3% 81.0%
3oqiA00 3.40.50.11710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cyclodipeptide synthase 0.57 52.0 3.58e-01 100.0% 53.6%
1d2mA03 6.10.140.240 Special › Helix non-globular › Helix Hairpins › 0.57 41.0 4.14e-01 77.3% 97.0%
4mouC02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.57 36.0 3.83e-01 86.4% 73.7%
3k9dA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.54 37.0 2.58e-01 72.7% 39.1%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 46.0 3.84e-01 100.0% 93.2%
1jxzC02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.52 34.0 3.58e-01 89.4% 75.0%
1gpeA03 3.30.560.10 Alpha Beta › 2-Layer Sandwich › Glucose Oxidase; domain 3 › Glucose Oxidase, domain 3 0.52 45.0 2.97e-01 100.0% 51.7%
4c3sA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.52 43.0 3.03e-01 100.0% 79.1%
3qqaA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 44.0 3.47e-01 98.5% 76.6%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3973819 191.1.1.21 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_18 0.85 65.0 4.83e-01 81.8% 35.9%
3970206 857.1.1.0 ↗ a+b duplicates or obligate multimers › Cell division protein ZapA-like › Cell division protein ZapA-like › Cell division protein ZapA-like 0.83 58.0 5.89e-01 75.8% 73.8%
3426642 375.1.1.96 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › YABBY 0.81 53.0 6.00e-01 77.3% 90.0%
4931613 140.1.1.11 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.80 57.0 3.99e-01 74.2% 29.6%
4956069 3646.1.1.0 ↗ alpha complex topology › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters › T-component of energy-coupling factor (ECF) transporters 0.80 61.0 4.12e-01 86.4% 24.1%
4339297 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 63.0 4.42e-01 84.8% 77.9%
3231907 2006.1.4.39 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › C_tripleX 0.77 51.0 5.83e-01 80.3% 100.0%
3648830 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.77 58.0 5.31e-01 83.3% 62.4%
3705890 190.1.1.1 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.76 51.0 4.47e-01 74.2% 47.4%
4929712 140.1.1.11 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.76 55.0 3.77e-01 77.3% 28.6%
4447919 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.75 63.0 4.61e-01 90.9% 50.9%
3930859 190.1.1.1 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.74 52.0 5.01e-01 75.8% 65.3%
4517192 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 57.0 4.09e-01 84.8% 74.2%
4600245 3640.1.1.1 ↗ alpha duplicates or obligate multimers › Minor ampullate fibroin 1 C-terminal domain › Minor ampullate fibroin 1 C-terminal domain › Minor ampullate fibroin 1 C-terminal domain › Spidroin_MaSp 0.72 61.0 5.71e-01 89.4% 79.7%
3284564 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.72 52.0 4.06e-01 75.8% 39.6%
3518379 3502.1.1.1 ↗ alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG 0.71 50.0 5.38e-01 74.2% 90.9%
4027661 592.1.1.1 ↗ alpha arrays › PWI domain-like › PWI domain › PWI domain › PWI 0.71 52.0 4.23e-01 77.3% 65.8%
3673805 148.1.3.285 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Cyclin_C 0.70 52.0 4.78e-01 80.3% 61.2%
4376234 4070.1.1.2 ↗ alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 0.70 55.0 3.73e-01 86.4% 28.6%
3497163 190.1.1.0 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box 0.70 49.0 4.64e-01 78.8% 61.3%
3503648 190.1.1.1 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.70 51.0 5.33e-01 77.3% 86.7%
3243101 6026.1.1.0 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain 0.69 53.0 4.42e-01 83.3% 47.8%
3974778 191.1.1.11 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_7 0.69 53.0 4.20e-01 84.8% 45.7%
4913800 101.11.1.1 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.68 55.0 5.19e-01 87.9% 75.9%
5051427 4070.1.1.2 ↗ alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 0.68 53.0 3.69e-01 86.4% 30.4%
3248213 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.68 62.0 4.04e-01 98.5% 27.7%
4858006 191.1.1.11 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_7 0.68 54.0 5.12e-01 86.4% 81.8%
3588902 223.1.1.0 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains 0.67 61.0 4.70e-01 100.0% 48.6%
3893243 190.1.1.9 ↗ alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_WDHD1 0.66 44.0 4.75e-01 72.7% 83.6%
3967043 142.1.1.3 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.66 51.0 4.51e-01 83.3% 57.9%
3628258 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 56.0 4.16e-01 92.4% 45.1%
3575 4084.1.1.1 ↗ alpha bundles › ChaB-like › ChaB-like › ChaB-like › ChaB 0.66 51.0 4.92e-01 90.9% 74.7%
3925598 2484.1.1.9 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › rve 0.64 54.0 3.96e-01 92.4% 72.0%
3884688 235.1.1.31 ↗ a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like › PF31087 0.64 60.0 4.25e-01 100.0% 41.1%
4976420 1074.1.1.0 ↗ alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases 0.64 44.0 3.83e-01 72.7% 70.5%
3207585 142.3.1.1 ↗ alpha complex topology › Sigma2 domain-like › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Mitochondrial morphogenesis protein Sld7 C-terminal domain › Sld7_C 0.62 45.0 4.32e-01 80.3% 67.5%
4026018 6026.1.1.1 ↗ alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain › cwf21 0.61 45.0 3.88e-01 83.3% 47.8%
3727148 7523.1.1.19 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › NMT1 0.60 48.0 3.52e-01 92.4% 78.5%
5065174 627.1.1.0 ↗ alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain 0.60 38.0 4.16e-01 84.8% 78.2%
2438944 129.1.1.8 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › HMD 0.59 52.0 3.93e-01 100.0% 73.3%
185221 3502.1.1.1 ↗ alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein › YebG 0.58 50.0 5.06e-01 97.0% 98.5%
4039240 4025.1.1.1 ↗ alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › Complex1_49kDa 0.57 48.0 3.45e-01 100.0% 85.9%
4028428 186.1.1.0 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.54 47.0 4.17e-01 100.0% 70.0%
4978899 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.54 38.0 3.57e-01 97.0% 60.0%