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GOV_bin_1711_contig-70_0_prodigal-single.1__X__X__00411

Bact-Vir

GOV_bin_1711_contig-70_0_prodigal-single.1__X__X__00411

Identity

Kingdom:
phage

Quality

90.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 456-603
PDB
Domain cluster: representative
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bdp002 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.88 60.0 7.00e-01 96.6% 94.5%
6vddA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.85 61.0 6.91e-01 96.6% 94.8%
7r0kA01 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.74 53.0 6.14e-01 79.1% 100.0%
3ay8A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 30.0 3.12e-01 87.8% 47.1%
2iazA00 1.20.1500.10 Mainly Alpha › Up-down Bundle › YheA-like fold › YheA/YmcA-like 0.62 40.0 4.62e-01 88.5% 88.0%
4k84A00 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.60 41.0 3.71e-01 91.9% 50.0%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.60 27.0 3.31e-01 86.5% 63.9%
2pihA00 1.20.1500.10 Mainly Alpha › Up-down Bundle › YheA-like fold › YheA/YmcA-like 0.58 40.0 4.33e-01 90.5% 84.6%
2yevB01 1.10.287.90 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 28.0 3.38e-01 93.2% 77.4%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.51 34.0 3.15e-01 91.9% 54.6%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4622747 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.90 64.0 4.72e-01 100.0% 31.3%
4339694 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.90 68.0 4.57e-01 100.0% 24.5%
4061480 2484.1.1.58 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Taq-exonuc 0.89 68.0 5.08e-01 100.0% 35.2%
3163747 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.89 68.0 4.51e-01 100.0% 23.5%
1391185 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.88 66.0 6.08e-01 100.0% 61.6%
4319500 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.88 68.0 4.54e-01 100.0% 24.4%
3964115 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.88 63.0 6.70e-01 93.9% 83.1%
3580212 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.85 53.0 6.60e-01 82.4% 97.9%
4995739 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.79 68.0 6.54e-01 100.0% 80.6%
4027632 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.76 56.0 6.23e-01 94.6% 94.2%
3277346 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.75 61.0 5.73e-01 100.0% 70.9%
3622196 604.1.1.63 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 0.69 36.0 3.97e-01 91.9% 61.7%
3991028 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.65 37.0 3.38e-01 94.6% 42.1%
3576126 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.63 28.0 3.00e-01 93.2% 46.4%
4182665 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.60 33.0 3.23e-01 95.9% 46.9%
4400266 4336.1.1.1 alpha duplicates or obligate multimers › YheA/YmcA-like › YheA/YmcA-like › YheA/YmcA-like › Com_YlbF 0.57 38.0 4.33e-01 87.2% 90.0%
4021783 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.54 46.0 4.70e-01 93.2% 93.1%
4117026 5069.1.1.56 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF27518 0.53 46.0 3.95e-01 91.9% 93.0%
4654104 150.3.1.5 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL2 0.52 37.0 3.75e-01 85.8% 72.0%
3939274 604.3.1.11 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF155 0.52 29.0 3.00e-01 75.7% 55.9%
3570611 626.1.1.1 alpha complex topology › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › FH2 0.52 38.0 2.85e-01 91.9% 28.5%
3713367 568.1.1.0 few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related 0.52 34.0 3.18e-01 83.8% 51.9%
5083443 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.51 38.0 3.54e-01 94.6% 62.0%
D2 medium residues 41-81_111-136_168-202
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ui0A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.92 88.0 6.85e-01 99.0% 80.2%
6ajpA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.92 87.0 6.66e-01 99.0% 80.6%
3nt7A00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.72 65.0 5.05e-01 98.0% 65.0%
3ikbA00 3.40.470.10 Alpha Beta › 3-Layer(aba) Sandwich › Uracil-DNA Glycosylase, subunit E › Uracil-DNA glycosylase-like domain 0.71 63.0 5.08e-01 98.0% 81.1%
2jbwA02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 55.0 4.12e-01 100.0% 84.4%
3mfqA02 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.57 49.0 4.53e-01 96.1% 90.4%
4cqbA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.55 47.0 3.41e-01 96.1% 99.0%
1lp1A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.51 26.0 3.38e-01 73.5% 89.1%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3386994 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.92 85.0 6.92e-01 97.1% 81.7%
5021506 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.92 87.0 6.90e-01 99.0% 78.4%
3057088 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.92 87.0 6.56e-01 99.0% 77.2%
4962559 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.92 87.0 6.87e-01 99.0% 82.2%
4968429 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.91 86.0 6.76e-01 99.0% 81.6%
4937539 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.89 84.0 6.65e-01 99.0% 80.5%
3590878 7569.1.1.1 a/b three-layered sandwiches › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › Uracil-DNA glycosylase-like › UDG 0.88 82.0 6.27e-01 99.0% 86.2%
3260351 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.51 42.0 4.16e-01 100.0% 84.5%
D3 medium residues 203-347_428-452
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01612.27 best DNA_pol_A_exo1 33.2 6.20e-08 82.9% 65.9%
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1d8yA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 74.0 6.75e-01 92.4% 99.5%
7r0kB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 71.0 6.11e-01 92.9% 100.0%
2d5rA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.78 66.0 5.67e-01 88.2% 100.0%
2e6mA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.77 57.0 5.57e-01 85.3% 69.4%
7jw6A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.77 64.0 5.84e-01 86.5% 99.5%
7jw2A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.74 59.0 5.49e-01 83.5% 100.0%
4nlcA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 66.0 5.61e-01 96.5% 77.5%
3safB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.72 66.0 5.47e-01 96.5% 74.3%
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 50.0 4.26e-01 72.9% 89.7%
3cymA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 66.0 6.09e-01 98.8% 100.0%
2xriA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.70 50.0 4.64e-01 72.4% 93.2%
7pbkA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.69 64.0 5.75e-01 96.5% 99.5%
1vk0A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.68 57.0 5.36e-01 87.1% 94.0%
6g62A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.52 35.0 4.09e-01 82.4% 98.3%
4ddnA00 2.100.10.30 Mainly Beta › Aligned Prism › Vitelline Membrane Outer Layer Protein I, subunit A › Jacalin-like lectin domain 0.51 31.0 3.24e-01 88.2% 64.3%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4037090 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.85 81.0 7.30e-01 99.4% 100.0%
4995738 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 77.0 6.97e-01 95.3% 100.0%
3266621 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 65.0 6.61e-01 78.8% 90.3%
3388110 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.82 77.0 5.99e-01 97.6% 66.7%
3407164 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.82 72.0 6.52e-01 91.8% 100.0%
3676005 4970.1.1.2 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_A 0.82 72.0 5.29e-01 91.8% 56.5%
4165451 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.81 78.0 6.72e-01 100.0% 93.9%
3961715 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.81 59.0 5.79e-01 85.3% 70.6%
160349 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 57.0 5.41e-01 81.2% 66.0%
3274022 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 69.0 5.95e-01 94.7% 87.8%
3313728 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.77 46.0 5.83e-01 84.7% 100.0%
3283743 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.76 73.0 5.66e-01 100.0% 64.2%
3705325 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 71.0 5.90e-01 97.6% 84.0%
3730951 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.76 67.0 5.67e-01 92.9% 82.6%
3412738 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.75 67.0 5.91e-01 94.7% 95.8%
4025342 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.75 66.0 5.82e-01 92.9% 100.0%
3555725 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.74 65.0 4.77e-01 92.4% 92.5%
3766382 2484.1.1.82 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_P_Exo 0.74 64.0 5.49e-01 91.2% 95.7%
3317395 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.73 67.0 5.82e-01 97.1% 89.6%
3936953 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 63.0 5.14e-01 91.2% 90.0%
3798192 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.72 65.0 5.86e-01 96.5% 99.6%
3578004 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 64.0 5.47e-01 94.7% 91.7%
2117499 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 55.0 5.23e-01 83.5% 67.5%
3937354 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 65.0 5.86e-01 96.5% 100.0%
3510945 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.72 56.0 5.17e-01 80.6% 71.0%
3997031 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.71 65.0 5.84e-01 95.9% 100.0%
3236261 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.71 65.0 5.64e-01 97.1% 94.4%
3817801 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.71 62.0 5.33e-01 92.9% 100.0%
3908305 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.71 58.0 5.45e-01 85.9% 90.7%
4603831 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.70 58.0 5.05e-01 85.3% 80.0%
3360497 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.70 59.0 5.60e-01 88.2% 99.5%
3528675 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.70 61.0 5.39e-01 91.2% 96.6%
3661219 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.70 59.0 5.32e-01 88.8% 87.6%
3937660 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.69 61.0 5.16e-01 93.5% 94.3%
3368406 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.68 57.0 5.41e-01 86.5% 98.5%
3435062 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.68 60.0 5.50e-01 94.1% 95.5%
3830378 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.67 55.0 5.26e-01 85.9% 98.5%
3818775 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.67 61.0 5.52e-01 96.5% 96.4%
3515806 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.66 47.0 5.25e-01 86.5% 92.6%
3234793 2484.1.1.20 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 0.60 49.0 5.00e-01 85.9% 99.4%
5748 4272.1.1.1 a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa 0.57 39.0 3.78e-01 94.1% 61.8%
3453547 2484.1.1.110 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MULE 0.54 42.0 3.61e-01 81.2% 81.1%
3881028 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 37.0 3.48e-01 77.6% 60.1%
3223923 7579.1.1.5 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10 0.51 46.0 2.61e-01 100.0% 34.9%
D4 medium residues 348-427
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ozbB01 1.10.287.4070 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 52.0 4.38e-01 76.2% 83.2%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.70 44.0 5.05e-01 75.0% 87.9%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.66 47.0 4.45e-01 76.2% 85.9%
4i0xH00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 49.0 5.05e-01 78.8% 82.9%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.65 45.0 4.80e-01 81.2% 81.7%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 47.0 4.93e-01 77.5% 87.3%
1vs5O00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.63 44.0 4.33e-01 73.8% 71.6%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.62 45.0 4.05e-01 78.8% 54.4%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.62 44.0 4.31e-01 80.0% 68.2%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 42.0 4.25e-01 73.8% 71.8%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 43.0 4.06e-01 75.0% 65.3%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.60 37.0 3.95e-01 88.7% 72.1%
1zhcA00 6.10.280.50 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 48.0 4.96e-01 91.3% 97.4%
4lwsB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 44.0 4.32e-01 80.0% 73.9%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 43.0 4.36e-01 76.2% 79.7%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.58 43.0 4.01e-01 78.8% 65.7%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.57 40.0 4.14e-01 72.5% 83.8%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.52 43.0 2.98e-01 88.7% 27.5%
3vkgA11 1.20.920.20 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.51 40.0 3.62e-01 83.7% 87.3%
6wb9201 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 37.0 2.65e-01 81.2% 79.9%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4965632 192.7.1.85 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › DUF4349 0.71 45.0 4.95e-01 77.5% 80.0%
5061758 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.70 53.0 5.43e-01 86.3% 84.0%
3731364 3922.1.1.137 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › HisKA 0.70 45.0 4.95e-01 78.8% 81.5%
4406905 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.69 46.0 4.87e-01 81.2% 78.6%
4335871 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.66 48.0 4.26e-01 75.0% 65.5%
3595968 605.2.1.0 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 0.65 47.0 4.76e-01 76.2% 75.0%
4231284 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.63 47.0 4.19e-01 78.8% 61.8%
3784740 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.62 47.0 4.83e-01 78.8% 84.0%
3471676 190.1.1.3 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box_2 0.60 50.0 4.93e-01 88.7% 87.1%
1002432 5071.3.1.1 alpha bundles › cytochrome bc1 complex 11 kDa protein-like › DUF465 › DUF465 › DUF465 0.59 48.0 4.96e-01 91.3% 97.4%
1495252 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.59 44.0 4.39e-01 80.0% 77.4%
3627448 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.59 45.0 4.04e-01 81.2% 61.8%
3857302 3543.1.1.4 alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF716 0.58 44.0 3.08e-01 80.0% 81.6%
4025 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.58 43.0 4.01e-01 78.8% 65.7%
3374031 109.27.1.0 alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain 0.55 43.0 3.83e-01 86.3% 70.0%
3786675 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.55 40.0 4.44e-01 76.2% 95.4%
D5 medium residues 604-650_810-948
PDB
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bgxT05 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.88 54.0 6.74e-01 75.3% 94.3%
4x0qA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.84 61.0 6.97e-01 78.0% 95.8%
3ofgB00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.72 35.0 5.09e-01 70.4% 100.0%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.72 37.0 5.13e-01 78.0% 98.9%
2dbbA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.70 34.0 4.88e-01 74.2% 95.7%
1vbkA01 3.30.70.1510 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like 0.70 33.0 4.80e-01 71.0% 100.0%
1jqgA01 3.30.70.340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like 0.69 33.0 4.50e-01 70.4% 90.1%
2a6mA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.66 42.0 5.00e-01 71.0% 91.5%
1q8kA03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.66 38.0 4.61e-01 71.5% 87.9%
2hiyA01 3.30.70.1280 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › SP0830-like domains 0.65 33.0 4.51e-01 74.2% 98.9%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.65 40.0 4.73e-01 70.4% 88.5%
3gqcC01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 42.0 4.86e-01 76.9% 89.1%
1lq9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 38.0 4.75e-01 74.2% 95.5%
3r5gA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.64 49.0 4.85e-01 78.0% 92.3%
2r7rA04 3.30.70.2480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 42.0 4.55e-01 93.5% 78.3%
3mtkA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 49.0 5.19e-01 79.6% 96.9%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 34.0 4.53e-01 70.4% 97.1%
6d9mA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 47.0 5.20e-01 77.4% 100.0%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.62 48.0 4.82e-01 79.6% 92.1%
1r6yA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 35.0 4.62e-01 71.0% 100.0%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 45.0 5.03e-01 91.9% 95.1%
4hkqA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 41.0 4.56e-01 95.2% 86.1%
1z2zA02 3.30.70.3160 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 29.0 3.94e-01 70.4% 92.2%
1r8gA00 3.30.590.20 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › 0.59 46.0 3.74e-01 81.2% 75.6%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.57 49.0 4.94e-01 90.3% 92.5%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.57 33.0 4.12e-01 72.6% 96.2%
1y10B02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.56 48.0 4.88e-01 89.2% 95.6%
1q2lA03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 42.0 3.95e-01 80.1% 86.5%
3aqpA02 3.30.70.3220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 41.0 4.44e-01 78.0% 100.0%
1ztpA01 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.54 43.0 4.10e-01 82.3% 87.7%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.52 37.0 4.03e-01 72.6% 86.2%
3c1mA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.52 37.0 3.98e-01 73.7% 88.4%
1qd1A01 3.30.990.10 Alpha Beta › 2-Layer Sandwich › Formiminotransferase-cyclodeaminase; Chain B, domain 1 › Formiminotransferase, N-terminal subdomain 0.51 38.0 3.89e-01 76.9% 99.4%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.50 38.0 4.02e-01 76.9% 89.7%
2c5sA01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.50 37.0 3.90e-01 75.8% 87.0%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3591785 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.80 58.0 6.53e-01 74.7% 96.0%
4779977 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.73 35.0 5.03e-01 70.4% 98.8%
3471440 304.24.1.3 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III 0.72 34.0 4.92e-01 71.0% 97.6%
4980062 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.72 35.0 4.80e-01 72.6% 90.5%
3173339 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.71 34.0 4.93e-01 71.5% 100.0%
3356626 304.48.1.21 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1,Thg1C 0.71 42.0 4.57e-01 71.5% 68.8%
3985253 304.28.1.8 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › YggL_50S_bp 0.71 35.0 4.70e-01 72.0% 87.4%
402953 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.67 42.0 4.74e-01 71.0% 80.9%
3703843 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.67 33.0 4.63e-01 70.4% 100.0%
5116 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.65 40.0 4.73e-01 70.4% 88.5%
3754642 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 3.37e-01 78.0% 30.0%
3486431 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 50.0 4.12e-01 80.1% 95.2%
None 0.64 49.0 3.38e-01 78.0% 30.8%
3941377 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 3.36e-01 78.0% 30.3%
3242055 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 3.43e-01 79.6% 30.5%
3924103 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 3.31e-01 79.6% 27.5%
3938603 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 3.37e-01 79.6% 29.4%
3902687 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 3.36e-01 79.6% 29.3%
3902327 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.64 49.0 4.17e-01 79.6% 60.7%
None 0.64 49.0 3.40e-01 79.6% 30.7%
None 0.63 49.0 3.44e-01 80.1% 31.8%
None 0.63 49.0 3.35e-01 79.6% 29.7%
None 0.63 49.0 3.39e-01 80.6% 30.0%
3876720 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 48.0 3.36e-01 79.6% 30.4%
None 0.63 49.0 3.50e-01 80.6% 34.9%
3582031 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.63 48.0 4.44e-01 79.6% 74.5%
None 0.63 48.0 4.30e-01 79.6% 69.0%
3241693 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 48.0 3.30e-01 79.6% 30.5%
None 0.62 49.0 3.50e-01 81.2% 34.7%
2803899 304.48.1.4 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.62 47.0 4.38e-01 78.0% 83.8%
3579157 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 48.0 3.44e-01 80.6% 36.0%
3485236 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 45.0 5.22e-01 78.0% 100.0%
3242514 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 47.0 3.27e-01 79.6% 29.7%
3224229 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 48.0 3.34e-01 80.1% 31.4%
3556174 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.58 44.0 4.13e-01 78.0% 72.4%
3967869 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.58 44.0 4.37e-01 76.9% 85.8%
3716499 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.57 44.0 4.12e-01 79.6% 72.4%
3550678 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.57 43.0 4.39e-01 77.4% 83.9%
4316367 304.55.2.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f 0.56 41.0 3.89e-01 74.2% 88.4%
3489049 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.56 43.0 2.83e-01 80.1% 22.7%
3502031 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.55 42.0 3.03e-01 79.6% 31.8%
None 0.55 43.0 3.00e-01 80.1% 30.0%
3600554 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.53 43.0 4.26e-01 86.0% 94.0%
3947661 304.48.1.48 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.52 45.0 4.70e-01 96.2% 100.0%
3302177 304.125.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in Api92-like proteins › ferredoxin-like domain in Api92-like proteins 0.51 31.0 3.86e-01 76.3% 99.1%
D6 medium residues 651-809
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00476.27 best DNA_pol_A 82.8 3.50e-23 100.0% 34.1%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4dsfA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.90 59.0 7.19e-01 100.0% 96.4%
4xviA01 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.86 73.0 7.67e-01 100.0% 96.5%
7pbkB02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.82 66.0 7.16e-01 100.0% 98.5%
3py8A04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.79 67.0 7.01e-01 100.0% 97.2%
4x0qA04 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.78 66.0 6.96e-01 100.0% 97.2%
7r0kA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.75 70.0 6.95e-01 99.4% 98.8%
1a04A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.73 32.0 4.55e-01 95.0% 83.7%
2w7nA00 1.10.10.2690 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.72 30.0 3.84e-01 70.4% 64.9%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.66 32.0 3.63e-01 94.3% 59.8%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.66 31.0 3.84e-01 96.9% 70.4%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.62 30.0 3.64e-01 96.9% 69.3%
1lnwF01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 29.0 3.32e-01 75.5% 57.3%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.61 29.0 3.35e-01 96.9% 59.1%
3ck6C02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.57 30.0 3.45e-01 96.2% 66.4%
3onqA03 1.10.10.2840 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain 0.57 32.0 3.48e-01 97.5% 65.6%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.56 26.0 3.05e-01 71.1% 59.6%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 30.0 3.27e-01 93.1% 64.2%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.54 33.0 3.32e-01 95.0% 59.1%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 36.0 3.69e-01 100.0% 70.1%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.53 30.0 3.60e-01 76.7% 84.5%
3v5uA01 6.10.280.80 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region 0.52 25.0 3.35e-01 74.8% 89.5%
4uiqB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 34.0 3.53e-01 95.6% 69.9%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.51 28.0 3.30e-01 96.2% 77.1%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4024558 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.95 75.0 8.05e-01 98.7% 91.4%
4169333 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.93 72.0 8.15e-01 91.8% 100.0%
4456463 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.93 74.0 8.24e-01 94.3% 100.0%
3969341 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.92 71.0 8.02e-01 90.6% 100.0%
3386797 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 76.0 6.57e-01 100.0% 60.3%
3259994 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 72.0 7.95e-01 96.9% 98.5%
3333780 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 76.0 8.17e-01 97.5% 97.9%
3277186 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.91 70.0 7.94e-01 88.1% 100.0%
3711347 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.90 75.0 8.00e-01 98.7% 97.1%
4876668 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.89 67.0 7.64e-01 89.9% 100.0%
3562851 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 75.0 7.86e-01 98.1% 95.9%
4217329 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.88 65.0 7.53e-01 89.9% 100.0%
4975020 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.88 65.0 7.07e-01 86.8% 88.9%
3595356 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.88 67.0 7.57e-01 91.8% 100.0%
2579554 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.87 72.0 7.49e-01 96.9% 91.2%
3483301 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.87 78.0 8.07e-01 96.9% 99.3%
4027630 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.86 64.0 7.35e-01 91.2% 100.0%
3423772 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.86 61.0 7.25e-01 83.6% 100.0%
3001792 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.86 62.0 7.23e-01 89.9% 100.0%
3581048 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.85 73.0 7.40e-01 100.0% 90.3%
4237263 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.84 62.0 7.17e-01 89.9% 100.0%
2970332 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.82 68.0 7.17e-01 97.5% 95.1%
4995740 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.81 62.0 6.94e-01 87.4% 100.0%
4848450 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.80 64.0 6.83e-01 95.0% 95.0%
3654151 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.80 75.0 7.41e-01 96.9% 97.6%
3704770 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.80 63.0 6.99e-01 89.3% 100.0%
3595646 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.79 74.0 7.53e-01 97.5% 98.7%
4617703 4964.1.1.1 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › DNA_pol_A 0.77 65.0 6.97e-01 89.9% 100.0%
3601930 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.76 71.0 6.67e-01 97.5% 94.6%
3718521 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.75 61.0 6.62e-01 89.3% 100.0%
3703169 4964.1.1.0 alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I 0.73 65.0 6.56e-01 92.5% 100.0%
3793393 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.71 37.0 5.05e-01 95.0% 98.8%
5079439 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.64 30.0 3.73e-01 95.6% 68.6%
5027752 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.63 33.0 4.42e-01 91.8% 98.8%
1503807 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.62 29.0 3.31e-01 96.2% 56.5%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 29.0 3.35e-01 96.2% 57.5%
3913655 101.1.3.0 alpha arrays › HTH › HTH › tetra-helical, LuxR-like 0.62 31.0 4.24e-01 70.4% 93.8%
5028151 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.61 32.0 4.20e-01 93.1% 92.9%
3280686 101.1.3.4 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 0.60 34.0 4.14e-01 100.0% 87.0%
3473135 601.16.1.2 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT 0.58 28.0 3.28e-01 71.1% 62.5%
3802509 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.58 34.0 3.47e-01 100.0% 59.3%
3946248 101.1.3.4 alpha arrays › HTH › HTH › tetra-helical, LuxR-like › HTH_30 0.57 33.0 4.05e-01 100.0% 89.0%
3255241 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.56 29.0 3.36e-01 73.6% 68.7%
3682662 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.55 33.0 3.62e-01 100.0% 71.5%