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GP27

Euk-Vir

Caviid_betaherpesvirus_2

GP27__YP_007417799__Caviid_betaherpesvirus_2__33706

Identity

Accession:: YP_007417799 ↗
Protein ID:: GP27
Kingdom:: euk

Quality

62.6 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Quwivirus› Caviid_betaherpesvirus_2

TaxID: 33706

Cluster

View cluster (26 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 197-274_289-383

PDB

D2 medium residues 7-52_80-123

PDB

Domain cluster: representative

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2zg6B01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.53	38.0	3.38e-01	75.6%	93.1%
1ak2A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.52	38.0	2.96e-01	80.0%	94.1%
5uivA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.52	38.0	2.92e-01	78.9%	88.0%
4pcfC00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.51	36.0	2.73e-01	74.4%	96.2%

ECOD (5)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4931457	7550.1.1.0 ↗	a/b three-layered sandwiches › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain › Tetrapyrrole methylase N-terminal domain	0.54	37.0	3.50e-01	71.1%	100.0%
3473510	7558.1.1.1 ↗	a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Acyltransferase	0.54	43.0	2.97e-01	86.7%	71.5%
5073892	7501.1.1.2 ↗	a/b three-layered sandwiches › Dihydrofolate reductases › Dihydrofolate reductases › Dihydrofolate reductases › RibD_C	0.51	37.0	2.96e-01	75.6%	93.2%
4940702	2004.1.1.79 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Thymidylate_kin	0.51	38.0	2.99e-01	78.9%	94.0%
3738899	2004.1.1.88 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › cobW	0.50	42.0	3.07e-01	92.2%	77.3%

D3 medium residues 124-196

PDB

Domain cluster: representative

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1sg6A02	1.20.1090.10	Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain	0.59	39.0	2.88e-01	80.8%	24.9%
1m62A00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.59	48.0	4.61e-01	97.3%	77.0%
6ketA01	3.20.20.30	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain	0.59	50.0	3.31e-01	98.6%	44.3%
3axjB02	1.20.58.200	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2	0.52	44.0	4.19e-01	94.5%	81.2%
3dliA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.51	39.0	2.81e-01	93.2%	27.6%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3948200	164.1.1.4 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › Anti-adapt_IraP	0.61	44.0	4.31e-01	82.2%	71.2%
3744220	611.3.1.0 ↗	alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	0.51	37.0	3.33e-01	98.6%	52.7%

D4 medium residues 389-473_516-548

PDB

Domain cluster: representative

CATH (25)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5k3hB04	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.74	54.0	5.24e-01	76.3%	93.2%
4nb5B02	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.74	40.0	5.32e-01	87.3%	98.4%
1sziA02	1.20.120.340	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS	0.73	49.0	4.70e-01	71.2%	59.1%
2i0mA01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.73	43.0	4.57e-01	91.5%	66.0%
3onjA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.70	40.0	4.42e-01	86.4%	69.1%
4v1gA00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.68	43.0	4.99e-01	87.3%	88.2%
4hyjA00	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.66	52.0	4.11e-01	83.1%	56.4%
4mh6A00	1.10.287.1700	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.66	42.0	3.79e-01	90.7%	47.8%
2rldA00	1.20.1440.60	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence	0.65	51.0	5.25e-01	82.2%	98.2%
2yfaA02	1.20.1440.210	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) ›	0.65	52.0	5.32e-01	84.7%	99.1%
6qumQ00	1.20.20.10	Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C	0.64	37.0	4.55e-01	86.4%	90.5%
5dkoA02	1.10.3900.10	Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like	0.64	44.0	3.91e-01	70.3%	76.0%
3kavA00	1.20.1270.360	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.63	48.0	5.11e-01	79.7%	100.0%
2q7rB00	1.20.120.550	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain	0.62	53.0	4.98e-01	93.2%	90.5%
3ck6C02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.60	37.0	3.76e-01	87.3%	61.3%
6c1qB02	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.60	49.0	3.70e-01	87.3%	86.4%
3teqB00	1.10.287.3550	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.60	40.0	4.32e-01	91.5%	80.2%
7sk7A01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.60	48.0	3.73e-01	85.6%	87.7%
3rvyA01	1.20.120.350	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C	0.59	39.0	4.00e-01	72.0%	68.4%
3kp9A01	1.20.1440.130	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain	0.57	47.0	4.27e-01	89.8%	81.5%
4akgA04	1.20.58.1120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4	0.57	42.0	3.84e-01	77.1%	58.3%
3ehfB01	6.10.250.2870	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.57	44.0	4.70e-01	83.1%	92.3%
4yonA01	1.20.900.10	Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain	0.57	47.0	3.91e-01	91.5%	78.7%
3sjqC00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.54	36.0	4.13e-01	85.6%	97.5%
7e4gA01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.51	45.0	3.84e-01	98.3%	85.3%

ECOD (38)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3736699	605.4.1.4 ↗	alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202	0.79	55.0	5.39e-01	71.2%	74.4%
3732358	604.12.1.42 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF202	0.76	53.0	5.58e-01	70.3%	86.7%
4612826	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.75	43.0	5.12e-01	86.4%	82.5%
2893266	5041.1.1.1 ↗	extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C	0.74	43.0	4.88e-01	87.3%	75.0%
3797475	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.74	51.0	4.02e-01	71.2%	72.1%
3805163	174.1.1.63 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PGG	0.72	56.0	5.32e-01	82.2%	99.3%
3287947	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.72	42.0	4.79e-01	86.4%	76.7%
4241935	632.7.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain	0.70	45.0	4.85e-01	71.2%	76.0%
3708019	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.69	48.0	4.94e-01	71.2%	86.1%
3707409	3567.1.1.0 ↗	a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer	0.69	43.0	4.44e-01	89.8%	64.3%
5010298	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.69	55.0	4.87e-01	83.1%	80.5%
3218207	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.69	59.0	5.48e-01	90.7%	94.5%
3286725	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.69	43.0	3.63e-01	89.0%	39.5%
3721550	3755.4.1.0 ↗	alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain	0.68	51.0	4.78e-01	78.0%	90.3%
5067970	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.68	55.0	5.93e-01	86.4%	99.0%
4479999	632.19.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A	0.68	42.0	4.46e-01	71.2%	69.5%
3447070	633.4.1.1 ↗	alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI	0.67	54.0	5.23e-01	85.6%	96.2%
3179505	633.23.1.22 ↗	alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL	0.66	55.0	5.04e-01	89.0%	96.1%
3737685	632.1.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain	0.66	46.0	5.08e-01	72.0%	98.9%
3225470	633.10.1.0 ↗	alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like	0.66	57.0	5.20e-01	93.2%	89.0%
5065387	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.66	54.0	5.53e-01	87.3%	98.2%
3661	633.10.1.1 ↗	alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › 23S_rRNA_IVP	0.65	51.0	5.27e-01	82.2%	99.1%
3914566	5001.1.1.1 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1	0.64	53.0	3.91e-01	86.4%	85.3%
3303180	174.1.1.1 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin	0.64	55.0	5.28e-01	92.4%	93.3%
3726229	604.1.1.58 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Helo_like_N	0.63	48.0	4.19e-01	78.0%	80.6%
4019714	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.63	49.0	4.96e-01	83.9%	100.0%
3262781	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.62	52.0	4.72e-01	89.8%	95.5%
3880276	174.1.1.34 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › FAM70	0.61	53.0	4.58e-01	94.9%	89.2%
4000583	5001.1.1.60 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx	0.60	47.0	3.93e-01	83.1%	75.5%
3744108	174.1.1.0 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain	0.60	51.0	4.78e-01	91.5%	95.9%
3390148	3615.1.1.0 ↗	alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain	0.59	51.0	5.00e-01	94.1%	100.0%
3875706	3615.1.1.0 ↗	alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain	0.58	51.0	4.68e-01	95.8%	93.5%
3928795	604.6.1.0 ↗	alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain	0.58	40.0	4.35e-01	71.2%	96.8%
4976893	633.21.1.0 ↗	alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107	0.57	47.0	4.85e-01	89.0%	100.0%
3780807	174.1.1.52 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27925	0.57	50.0	4.88e-01	96.6%	99.2%
4018032	174.1.1.18 ↗	few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Erv26	0.55	43.0	3.89e-01	82.2%	82.5%
3657174	5069.1.1.7 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561	0.55	49.0	4.42e-01	99.2%	80.0%
4051450	5053.1.1.1 ↗	alpha complex topology › Clc chloride channel › Clc chloride channel › Clc chloride channel › Voltage_CLC	0.51	43.0	3.03e-01	94.1%	79.3%