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GP75

Euk-Vir

Caviid_betaherpesvirus_2

GP75__YP_007417841__Caviid_betaherpesvirus_2__33706

Identity

Accession:
YP_007417841 ↗
Protein ID:
GP75
Kingdom:
euk

Quality

80.1 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Quwivirus› Caviid_betaherpesvirus_2

TaxID: 33706

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 26-99
PDB
D2 medium residues 130-169_368-437
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7yb9A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 48.0 3.88e-01 89.1% 53.2%
3d1uA03 1.20.1270.240 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 30.0 3.16e-01 72.7% 51.5%
2kckA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 45.0 4.57e-01 86.4% 83.0%
3vhlA02 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.57 40.0 3.90e-01 71.8% 98.3%
3as5A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 48.0 4.06e-01 90.9% 79.8%
3u4tB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 47.0 3.61e-01 91.8% 43.6%
3kwoA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 38.0 3.46e-01 70.0% 91.3%
2c2lA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 44.0 4.18e-01 85.5% 93.2%
8f5oD01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 46.0 3.14e-01 90.0% 26.8%
6hftA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 43.0 4.13e-01 85.5% 73.2%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 35.0 4.04e-01 90.0% 92.3%
4c23B01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 42.0 3.43e-01 88.2% 81.2%
1rz4A01 1.25.40.250 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat; domain 1 0.53 41.0 4.02e-01 90.9% 75.8%
3t9jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 36.0 3.32e-01 70.0% 97.9%
2zgyA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 37.0 3.44e-01 76.4% 89.3%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3209285 109.4.1.791 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 0.60 44.0 4.68e-01 85.5% 89.5%
3315274 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 48.0 4.12e-01 89.1% 58.3%
4341411 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.58 38.0 4.46e-01 70.0% 100.0%
4564182 109.4.1.1685 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27595, PF30849 0.58 47.0 3.24e-01 89.1% 35.0%
4969118 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 48.0 3.43e-01 90.9% 30.6%
3207454 109.4.1.43 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SAC3_GANP 0.56 45.0 3.53e-01 87.3% 52.2%
3276399 109.4.1.1924 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RALGAPB_N, PF27567 0.56 50.0 2.90e-01 100.0% 36.1%
3815352 109.4.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.55 49.0 2.87e-01 100.0% 16.9%
3495181 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 47.0 3.60e-01 96.4% 83.8%
3385019 109.4.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.54 49.0 2.77e-01 100.0% 18.0%
3226778 4106.1.1.1 ↗ few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.54 41.0 3.43e-01 79.1% 92.1%
3515155 109.30.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin Nup84/Nup107 › Nucleoporin Nup84/Nup107 › Nup84_Nup100 0.54 49.0 3.14e-01 100.0% 49.3%
3324184 109.4.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm 0.54 48.0 2.91e-01 100.0% 22.8%
3510805 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 47.0 4.28e-01 94.5% 94.5%
3773580 109.4.1.1452 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_Maestro, HEAT_Maestro_2 0.54 45.0 2.99e-01 97.3% 55.0%
3459632 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.53 43.0 3.12e-01 90.0% 30.2%
3174089 109.4.1.435 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RICTOR_N 0.53 44.0 3.63e-01 92.7% 76.7%
3879800 601.3.1.8 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › IQUB 0.52 39.0 3.61e-01 90.9% 61.4%
3811905 109.2.1.7 ↗ alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Terpene_synth 0.50 38.0 3.17e-01 80.0% 62.1%
D3 medium residues 170-273
PDB
Domain cluster: rep: orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184__D149-254
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 46.0 4.40e-12 100.0% 20.6%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3bxoA02 2.20.130.10 Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › CAC2371-like domains 0.71 35.0 4.58e-01 70.2% 84.7%
4r80A00 3.10.450.630 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.71 42.0 4.80e-01 84.6% 80.3%
6fmeA03 2.20.220.10 Mainly Beta › Single Sheet › Glycosyl hydrolase fold › alpha-Amylases 0.69 41.0 5.20e-01 90.4% 100.0%
8gq6A01 2.120.10.80 Mainly Beta › 6 Propeller › Neuraminidase › Kelch-type beta propeller 0.66 36.0 2.61e-01 77.9% 18.9%
1omoA01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.64 47.0 4.18e-01 76.9% 91.9%
1x7dB01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.63 47.0 4.00e-01 78.8% 81.1%
1s3rA03 3.40.30.40 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Perfringolysin 0.62 48.0 4.41e-01 79.8% 89.9%
7wffb01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.60 52.0 3.74e-01 95.2% 86.8%
3obaA05 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.58 51.0 3.67e-01 95.2% 81.2%
2ns9A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.58 41.0 3.63e-01 73.1% 68.9%
1rwhA02 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.57 51.0 3.79e-01 98.1% 83.0%
1yqfB00 3.10.280.10 Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein 0.56 41.0 3.37e-01 82.7% 44.1%
3nreA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.56 48.0 3.48e-01 94.2% 80.1%
2vckA00 3.40.1500.20 Alpha Beta › 3-Layer(aba) Sandwich › oxygen-dependent coproporphyrinogen oxidase › 0.55 48.0 3.91e-01 98.1% 88.0%
1whqA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.55 37.0 4.29e-01 84.6% 100.0%
2i0oA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.54 42.0 3.07e-01 82.7% 75.6%
1l0oA00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.54 38.0 3.37e-01 71.2% 99.3%
1mdcA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 45.0 4.14e-01 88.5% 90.8%
3h0gH00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 44.0 4.19e-01 89.4% 78.2%
4ba0A04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.53 40.0 3.66e-01 82.7% 75.2%
4amwA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.53 41.0 3.67e-01 81.7% 79.1%
3wy2A03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 31.0 3.64e-01 84.6% 84.9%
2wc7A02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 33.0 3.78e-01 100.0% 86.1%
2pcsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 44.0 3.89e-01 92.3% 80.3%
3zghA00 2.60.40.3400 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 42.0 3.49e-01 86.5% 89.3%
3d4eA01 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.51 37.0 4.04e-01 84.6% 92.9%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 42.0 3.89e-01 90.4% 68.1%
3k25A00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.51 39.0 2.97e-01 85.6% 78.1%
4o4oA00 2.40.128.590 Mainly Beta › Beta Barrel › Lipocalin › CpcT/CpeT domain 0.50 44.0 3.53e-01 94.2% 66.5%
1o8vA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.50 42.0 3.89e-01 89.4% 89.5%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095503 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.91 79.0 4.85e-01 100.0% 18.0%
3812869 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.78 45.0 4.58e-01 79.8% 59.0%
3990496 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.73 44.0 5.22e-01 86.5% 88.6%
3224967 207.1.1.81 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.71 35.0 2.61e-01 78.8% 19.2%
4008120 5.1.5.139 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DUF1481 0.70 47.0 4.45e-01 84.6% 59.2%
5019886 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.69 41.0 4.75e-01 82.7% 81.3%
4033933 9.9.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Hypothetical protein YwiB › Hypothetical protein YwiB › DUF1934 0.69 40.0 3.87e-01 84.6% 52.2%
4033429 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.66 37.0 4.18e-01 84.6% 71.2%
5033173 5084.1.1.0 ↗ beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like 0.64 42.0 4.17e-01 92.3% 63.3%
4507204 213.1.1.0 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.63 41.0 3.60e-01 84.6% 43.9%
4109711 12.3.1.24 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › YidC_periplas 0.61 52.0 3.91e-01 95.2% 84.8%
5011042 3692.1.1.0 ↗ a+b two layers › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain 0.60 47.0 4.34e-01 82.7% 90.0%
4883232 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.59 53.0 3.82e-01 98.1% 87.5%
4152335 9.2.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › Avidin 0.59 50.0 4.69e-01 90.4% 84.7%
3326913 12.3.1.2 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Cu_amine_oxid 0.59 46.0 3.49e-01 83.7% 90.4%
4208434 12.3.1.24 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › YidC_periplas 0.56 48.0 3.51e-01 95.2% 81.7%
3699767 295.1.1.7 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › MRP 0.56 46.0 3.93e-01 88.5% 70.9%
4009823 5084.5.1.19 ↗ beta barrels › Outer membrane meander beta-barrels › Porins › Porin › AsmA 0.55 48.0 3.40e-01 97.1% 44.2%
3977969 9.11.1.0 ↗ beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like 0.55 43.0 4.22e-01 90.4% 77.3%
4825040 12.3.1.13 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C 0.55 44.0 3.93e-01 84.6% 87.3%
3923717 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.54 45.0 3.61e-01 90.4% 57.1%
3276491 12.2.1.8 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Hyaluronate lyase-like, C-terminal domain › Hyaluronate lyase-like, C-terminal domain › UPF0556 0.54 42.0 3.93e-01 82.7% 89.1%
3309307 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.53 43.0 2.60e-01 85.6% 26.9%
3934509 3369.1.1.0 ↗ beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 0.53 46.0 3.82e-01 95.2% 64.3%
3809562 883.1.1.20 ↗ a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › SMP_MUG190-like 0.53 46.0 3.72e-01 95.2% 88.5%
3394516 241.15.1.2 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › PI31_Prot_N 0.53 39.0 3.49e-01 85.6% 55.6%
3598820 5084.5.1.0 ↗ beta barrels › Outer membrane meander beta-barrels › Porins › Porin 0.53 46.0 3.34e-01 93.3% 63.6%
3230776 5.1.4.21 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Pep3_Vps18 0.52 47.0 3.15e-01 96.2% 37.3%
3165921 881.4.1.1 ↗ a+b three layers › Mog1p/PsbP-like › C-terminal domain in sigma-E factor regulatory protein rseB › C-terminal domain in sigma-E factor regulatory protein rseB › MucB_RseB_C 0.51 39.0 4.13e-01 91.3% 89.5%
3658278 5.1.3.142 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_AT5G49610-like 0.51 44.0 3.01e-01 90.4% 30.3%
3951937 330.8.1.1 ↗ a+b two layers › dsRBD-like › Rv2632c-like › Rv2632c-like › Rv2632c-like 0.51 36.0 3.87e-01 73.1% 85.4%
4663376 3593.1.1.1 ↗ a+b complex topology › Oncogenic effector CagA meander beta sheet domain › Oncogenic effector CagA meander beta sheet domain › Oncogenic effector CagA meander beta sheet domain › CagA_N 0.51 46.0 3.11e-01 100.0% 80.8%
3744477 897.1.1.1 ↗ a+b two layers › Acidic mitochondrial matrix protein p32-like › Acidic mitochondrial matrix protein p32 › Acidic mitochondrial matrix protein p32 › MAM33 0.51 39.0 3.24e-01 81.7% 48.9%
5057645 9.2.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin 0.50 41.0 4.02e-01 89.4% 80.9%
D4 medium residues 274-367
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_081523__Human_betaherpesvirus_5__10359__D285-357
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 26.6 3.30e-06 100.0% 20.4%
CATH (47)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 56.0 6.23e-01 84.0% 92.0%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.80 62.0 5.14e-01 83.0% 100.0%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 59.0 5.83e-01 79.8% 81.2%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 55.0 5.62e-01 86.2% 75.3%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 54.0 5.38e-01 80.9% 70.1%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.76 61.0 5.61e-01 84.0% 78.6%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.76 58.0 5.00e-01 84.0% 52.4%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 53.0 5.80e-01 85.1% 92.0%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.74 55.0 4.97e-01 84.0% 57.9%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.74 58.0 5.33e-01 84.0% 65.5%
2vgxB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 52.0 4.49e-01 91.5% 48.3%
2fefA01 1.20.1440.70 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › PA2201 N-terminal domain-like 0.71 55.0 5.04e-01 85.1% 62.4%
2b1eA01 1.20.58.1150 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 52.0 5.43e-01 85.1% 84.9%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.70 55.0 5.14e-01 84.0% 76.1%
3ezhA00 1.20.120.960 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain 0.69 51.0 4.80e-01 84.0% 64.0%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.69 53.0 4.87e-01 80.9% 69.2%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.69 55.0 4.68e-01 86.2% 64.1%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.69 52.0 4.95e-01 80.9% 88.4%
2o36A01 1.20.1050.40 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 0.68 52.0 4.72e-01 81.9% 87.5%
2pftA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.68 57.0 3.60e-01 94.7% 23.5%
6xkyA01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.68 53.0 4.19e-01 83.0% 51.9%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 53.0 4.95e-01 85.1% 71.8%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 49.0 5.35e-01 89.4% 97.3%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 52.0 4.45e-01 84.0% 91.0%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 52.0 5.10e-01 84.0% 86.3%
1qazA00 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.66 55.0 3.76e-01 91.5% 27.1%
5cy5B00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.66 51.0 4.43e-01 84.0% 95.3%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.66 55.0 4.67e-01 92.6% 89.1%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 50.0 4.49e-01 84.0% 90.4%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.65 52.0 4.13e-01 85.1% 60.6%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 36.0 3.85e-01 92.6% 64.2%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.62 51.0 4.82e-01 98.9% 74.6%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.60 52.0 4.49e-01 98.9% 80.0%
1kz7A01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.60 50.0 4.10e-01 96.8% 87.6%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 46.0 4.01e-01 84.0% 94.6%
3mvpA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 44.0 3.84e-01 80.9% 89.9%
5xdcB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.58 43.0 4.08e-01 77.7% 67.6%
1bbhA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.58 45.0 4.08e-01 84.0% 83.2%
7zb5E01 3.40.50.10810 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain 0.57 51.0 3.62e-01 100.0% 64.2%
8cdaC01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.57 42.0 3.95e-01 77.7% 64.1%
4n1yB00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.54 46.0 3.45e-01 91.5% 74.9%
4ip8A00 1.10.132.110 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein 0.54 45.0 4.39e-01 93.6% 83.8%
2rekA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 46.0 3.84e-01 96.8% 58.7%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 41.0 3.73e-01 84.0% 64.4%
5gj7A01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.53 45.0 4.13e-01 94.7% 75.2%
6i57A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 37.0 3.44e-01 91.5% 55.2%
7vkcA01 1.10.1070.20 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › 0.52 43.0 3.71e-01 95.7% 81.8%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3212257 601.33.1.10 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › DUF19 0.79 57.0 5.54e-01 84.0% 67.6%
3440132 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.79 61.0 3.68e-01 84.0% 13.6%
3955636 604.12.1.106 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF28475 0.79 55.0 6.08e-01 81.9% 90.7%
3741922 109.4.1.335 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SEN1_N 0.78 72.0 5.14e-01 100.0% 38.8%
4998039 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.78 62.0 6.15e-01 85.1% 81.0%
3584478 1134.1.1.0 ↗ alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.76 56.0 5.70e-01 84.0% 80.0%
5072045 604.10.1.0 ↗ alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac 0.76 60.0 5.83e-01 84.0% 82.9%
3309012 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.76 60.0 5.58e-01 84.0% 71.3%
4049101 603.2.1.1 ↗ alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.75 59.0 5.03e-01 84.0% 70.0%
4286404 3755.1.1.14 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › T3SSipB 0.75 59.0 4.72e-01 84.0% 84.4%
3628598 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 57.0 6.08e-01 84.0% 95.0%
3877040 1134.1.1.0 ↗ alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.74 52.0 5.77e-01 84.0% 92.0%
1711732 601.2.1.7 ↗ alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › HBM 0.74 58.0 5.32e-01 84.0% 65.0%
5024001 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.74 64.0 6.33e-01 95.7% 95.0%
4004067 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.74 56.0 5.87e-01 85.1% 89.4%
3498448 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.73 56.0 5.99e-01 84.0% 95.0%
4440290 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.73 56.0 6.11e-01 79.8% 100.0%
3626530 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 58.0 5.78e-01 84.0% 90.5%
3441147 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.72 55.0 5.78e-01 80.9% 90.6%
3247003 109.4.1.941 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › LTN1_E3_ligase_5th 0.72 62.0 4.52e-01 95.7% 67.9%
4048066 109.4.1.471 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GCFC 0.72 64.0 4.85e-01 100.0% 41.8%
3429544 109.52.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › FRIGIDA flowering-time regulator › FRIGIDA flowering-time regulator › Frigida 0.72 59.0 4.19e-01 89.4% 34.7%
3218730 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.72 52.0 5.65e-01 83.0% 94.7%
3693073 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.72 52.0 5.26e-01 85.1% 76.8%
3584048 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 54.0 5.55e-01 84.0% 84.4%
4027056 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 64.0 5.58e-01 98.9% 93.6%
2060764 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.71 64.0 5.80e-01 100.0% 89.8%
3966840 150.1.1.8 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF2383 0.71 56.0 4.82e-01 84.0% 92.4%
3940580 604.6.1.14 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › RasGAP_C 0.71 55.0 5.11e-01 81.9% 75.7%
3319968 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 49.0 5.54e-01 80.9% 97.1%
3763743 109.4.1.471 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GCFC 0.70 62.0 3.98e-01 100.0% 20.9%
3258984 601.25.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.70 55.0 4.58e-01 84.0% 57.0%
3832084 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 51.0 5.54e-01 84.0% 97.3%
4971759 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.69 47.0 4.11e-01 70.2% 87.9%
3709421 604.12.1.2 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.68 49.0 5.10e-01 84.0% 83.5%
5036565 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.68 60.0 4.69e-01 93.6% 78.9%
3500905 604.13.1.1 ↗ alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer 0.68 57.0 5.23e-01 100.0% 70.4%
4979381 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.67 56.0 4.32e-01 90.4% 45.5%
4029030 3559.1.1.0 ↗ a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 0.67 46.0 4.58e-01 71.3% 90.0%
3711224 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.67 52.0 5.08e-01 84.0% 79.0%
4990095 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.66 49.0 5.13e-01 84.0% 85.9%
3743879 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.66 51.0 5.14e-01 84.0% 82.1%
4940283 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.66 55.0 4.49e-01 93.6% 49.5%
5023839 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.66 56.0 4.40e-01 94.7% 46.5%
3236284 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 50.0 5.36e-01 84.0% 96.2%
3169342 109.4.1.381 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rrn11 0.65 58.0 4.40e-01 100.0% 64.4%
3613133 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 50.0 5.17e-01 84.0% 91.8%
3373578 109.4.1.163 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SYMPK_PTA1_N 0.65 55.0 4.51e-01 95.7% 67.8%
5065508 192.15.1.0 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.64 49.0 4.81e-01 79.8% 80.0%
3286634 109.3.1.160 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › EccD 0.63 55.0 3.85e-01 98.9% 41.2%
3592632 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.61 46.0 4.68e-01 85.1% 82.1%
4028009 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.61 54.0 4.67e-01 100.0% 88.0%
4944333 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.60 47.0 4.29e-01 85.1% 63.2%
3996074 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 52.0 3.87e-01 100.0% 47.3%
3274423 109.4.1.1224 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DOCK9 0.60 52.0 3.25e-01 100.0% 17.2%
3743652 109.4.1.451 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Iml2-TPR_39 0.58 49.0 3.61e-01 95.7% 51.9%
4982026 150.1.1.209 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7121 0.56 44.0 3.78e-01 83.0% 54.3%
4973925 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.51 42.0 2.99e-01 92.6% 47.5%
3487928 3277.2.1.0 ↗ alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 0.51 41.0 3.88e-01 88.3% 89.6%
D5 medium residues 438-540
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_009388523__Common_bottlenose_dolphin_gammaherpesvirus_1_strain_Sarasota__2022783__D447-588
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 50.3 2.20e-13 96.1% 19.4%
D6 medium residues 541-692
PDB
Domain cluster: rep: envelope_glycoprotein_H__NP_077452__Cercopithecine_alphaherpesvirus_9__35246__D674-695_717-808
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 118.4 2.70e-34 92.8% 98.6%