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GQ452243.1__ACV83347.1__PHIEF11_0029__00029

Bact-Vir

GQ452243.1__ACV83347.1__PHIEF11_0029__00029

Identity

Accession:
GQ452243 ↗
Kingdom:
phage

Quality

92.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 385-497
PDB
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5oesA04 3.40.50.1760 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glutathione synthase, substrate-binding domain superfamily, eukaryotic 0.59 43.0 4.19e-01 100.0% 69.4%
1m0wA04 3.40.50.1760 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glutathione synthase, substrate-binding domain superfamily, eukaryotic 0.55 42.0 4.08e-01 100.0% 70.5%
1hkgA02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.54 38.0 3.68e-01 77.9% 63.8%
2ox6D00 1.10.3100.10 Mainly Alpha › Orthogonal Bundle › Putative cytoplasmic protein › Putative cytoplasmic protein 0.53 45.0 4.05e-01 97.3% 65.8%
3htvA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.53 34.0 3.46e-01 72.6% 65.8%
7eqiA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.53 40.0 3.69e-01 100.0% 60.1%
4xr9B02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 45.0 3.66e-01 92.9% 67.9%
3g79A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 43.0 3.35e-01 92.9% 53.8%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4502816 3008.1.1.0 a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.59 40.0 4.62e-01 98.2% 98.8%
4491858 3008.1.1.0 a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.55 41.0 4.50e-01 96.5% 97.8%
4975908 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.53 40.0 3.30e-01 80.5% 92.7%
3284695 7581.1.1.0 a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like 0.50 44.0 4.02e-01 94.7% 73.1%
3662429 4143.1.1.0 a+b two layers › THUMP domain-like › THUMP domain-like › THUMP domain-like 0.50 43.0 4.11e-01 94.7% 81.5%
D2 medium residues 1-153
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14264.13 best Glucos_trans_II 43.9 2.40e-11 83.0% 35.6%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 34.0 4.52e-01 81.0% 100.0%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.60 27.0 3.39e-01 98.0% 68.1%
4an8A02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.59 37.0 4.08e-01 81.0% 77.0%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.59 33.0 4.12e-01 85.0% 94.1%
7akwA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 42.0 3.72e-01 74.5% 99.1%
7yu4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.58 44.0 3.76e-01 81.0% 98.8%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.57 32.0 4.08e-01 79.1% 96.6%
1r2jA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 36.0 3.76e-01 73.2% 73.6%
3ljbA00 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.52 38.0 3.38e-01 80.4% 52.5%
2au5A00 1.20.120.590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › EF2947-like 0.52 33.0 3.53e-01 80.4% 74.4%
2uxwA04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.52 34.0 3.65e-01 77.1% 76.9%
4fz4A00 1.20.140.130 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.51 40.0 4.06e-01 96.1% 82.5%
7sf8A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.50 43.0 3.73e-01 97.4% 59.3%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3881034 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 43.0 3.40e-01 80.4% 90.0%
5048730 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.52 38.0 3.67e-01 92.2% 67.1%
4012236 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.51 39.0 3.83e-01 89.5% 75.6%
4948186 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 43.0 3.84e-01 100.0% 64.4%
D3 medium residues 154-243
PDB
Domain cluster: representative
CATH (48)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.79 59.0 4.80e-01 77.8% 47.8%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.77 55.0 5.93e-01 75.6% 92.3%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 51.0 5.42e-01 83.3% 78.5%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 61.0 5.77e-01 88.9% 79.6%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.72 49.0 5.30e-01 82.2% 83.1%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.71 57.0 4.30e-01 85.6% 74.9%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.70 54.0 5.45e-01 83.3% 83.7%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 58.0 5.34e-01 88.9% 93.8%
1p49A02 1.10.287.550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 42.0 5.14e-01 74.4% 94.9%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.68 48.0 5.33e-01 83.3% 93.1%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 44.0 4.82e-01 77.8% 81.3%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 45.0 4.98e-01 82.2% 86.3%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.67 44.0 4.52e-01 83.3% 69.8%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 46.0 4.89e-01 82.2% 83.1%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.65 50.0 5.08e-01 82.2% 83.9%
1rv2D04 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.65 42.0 4.60e-01 83.3% 82.9%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 48.0 4.53e-01 77.8% 99.1%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 50.0 4.48e-01 83.3% 65.4%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 49.0 4.80e-01 83.3% 73.0%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.64 46.0 4.26e-01 83.3% 58.8%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.64 48.0 4.21e-01 82.2% 53.3%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 42.0 4.53e-01 80.0% 79.2%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.63 50.0 4.43e-01 86.7% 59.3%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 38.0 4.03e-01 71.1% 66.7%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.63 44.0 4.47e-01 83.3% 72.2%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.63 46.0 4.72e-01 85.6% 78.7%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 43.0 4.74e-01 85.6% 88.9%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 44.0 4.84e-01 83.3% 90.5%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.61 50.0 4.10e-01 88.9% 93.5%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.61 42.0 4.66e-01 82.2% 94.1%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.61 48.0 4.84e-01 83.3% 84.1%
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 40.0 4.16e-01 75.6% 71.4%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 49.0 4.05e-01 86.7% 84.3%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 44.0 4.35e-01 81.1% 70.7%
5dsgA01 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.60 31.0 2.98e-01 82.2% 42.5%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.60 50.0 4.46e-01 93.3% 68.4%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.59 42.0 3.80e-01 74.4% 82.3%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 45.0 3.56e-01 87.8% 54.5%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.55 48.0 3.99e-01 97.8% 90.2%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 43.0 4.14e-01 83.3% 82.4%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.55 41.0 4.54e-01 93.3% 100.0%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 37.0 3.72e-01 81.1% 67.7%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 45.0 4.10e-01 88.9% 68.6%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 45.0 4.18e-01 90.0% 95.5%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 35.0 3.66e-01 72.2% 84.7%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.51 39.0 4.06e-01 87.8% 88.2%
1vfiA00 1.10.246.100 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Vanadium-binding protein 2 0.51 41.0 4.03e-01 87.8% 94.7%
1ak2A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 39.0 2.96e-01 84.4% 73.2%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3516870 5094.1.1.0 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like 0.82 58.0 5.49e-01 73.3% 65.7%
3404270 377.1.1.0 few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.81 60.0 5.23e-01 76.7% 87.7%
3570028 904.1.1.0 few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain 0.81 60.0 4.72e-01 77.8% 41.1%
3386352 4207.1.1.104 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Bac_export_2 0.75 56.0 5.18e-01 77.8% 65.5%
4223385 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.72 55.0 5.35e-01 80.0% 77.0%
5026085 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.71 58.0 5.47e-01 87.8% 98.1%
4080313 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.71 57.0 4.97e-01 87.8% 77.1%
3975557 3782.1.1.0 a+b duplicates or obligate multimers › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related › Envelope glycoprotein GP2-related 0.71 46.0 5.23e-01 71.1% 92.3%
3564399 3755.3.1.282 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tmemb_cc2 0.68 51.0 4.71e-01 83.3% 61.7%
5002748 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.68 45.0 4.92e-01 86.7% 81.3%
3686172 109.4.1.496 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec5 0.68 61.0 3.64e-01 100.0% 38.6%
4253651 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.67 52.0 5.38e-01 85.6% 87.1%
3933170 605.4.1.0 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein 0.67 52.0 5.01e-01 82.2% 79.0%
3219809 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.66 48.0 4.49e-01 75.6% 61.8%
3756535 604.1.1.5 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_3 0.66 55.0 5.06e-01 90.0% 80.9%
4979163 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.66 52.0 4.33e-01 86.7% 49.0%
3192129 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.66 50.0 3.76e-01 80.0% 61.0%
4016253 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.66 47.0 4.49e-01 83.3% 63.8%
3968763 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.65 43.0 4.52e-01 87.8% 75.0%
3990854 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.65 49.0 4.93e-01 84.4% 77.8%
4143464 4177.1.1.102 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Med29 0.65 48.0 3.97e-01 86.7% 43.7%
3992912 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 52.0 4.41e-01 86.7% 88.7%
3556027 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.65 46.0 4.76e-01 86.7% 77.6%
3855461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.65 46.0 4.75e-01 86.7% 77.6%
3618907 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.65 46.0 3.48e-01 75.6% 48.4%
4010416 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.64 46.0 4.10e-01 86.7% 53.6%
3902100 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.64 46.0 4.75e-01 85.6% 78.8%
5020418 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.64 44.0 3.79e-01 75.6% 45.7%
5026881 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.64 46.0 4.99e-01 82.2% 90.7%
4406698 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.63 48.0 4.76e-01 86.7% 75.8%
4365052 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.62 46.0 4.53e-01 77.8% 86.3%
3672993 150.5.1.6 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › DUF3082 0.62 47.0 4.37e-01 84.4% 63.5%
3305901 611.9.1.0 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.62 43.0 3.74e-01 72.2% 48.1%
4177674 4992.1.1.23 extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.62 44.0 4.13e-01 86.7% 60.9%
3896730 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 50.0 4.38e-01 88.9% 92.6%
3397545 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.61 49.0 4.21e-01 87.8% 55.0%
3548194 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.61 49.0 4.57e-01 86.7% 70.0%
3932320 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.61 48.0 4.13e-01 84.4% 54.3%
3711734 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.60 49.0 3.97e-01 86.7% 58.2%
4025 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.60 44.0 4.35e-01 81.1% 70.7%
3393794 3922.1.1.211 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C 0.60 51.0 4.57e-01 97.8% 98.5%
4003837 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.60 46.0 4.48e-01 86.7% 74.0%
3944006 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.60 46.0 4.14e-01 82.2% 92.0%
3725506 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.60 50.0 4.67e-01 90.0% 98.2%
2770964 5073.1.3.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Potassium-transporting ATPase subunit KdpB transmembrane domain 0.59 43.0 4.00e-01 77.8% 67.8%
3306934 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.58 42.0 3.92e-01 87.8% 60.9%
4028552 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 48.0 3.50e-01 88.9% 53.9%
4973614 5069.1.3.26 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF1622 0.58 47.0 4.44e-01 94.4% 71.8%
3488979 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.58 44.0 3.93e-01 82.2% 57.6%
3754639 150.5.1.106 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › LIN9_C 0.57 40.0 4.17e-01 86.7% 77.6%
3840952 601.19.1.39 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › LIN9_C 0.57 42.0 4.55e-01 84.4% 93.3%
3599614 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.57 43.0 3.06e-01 81.1% 67.9%
3445025 174.1.1.2 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Jagunal 0.57 46.0 3.83e-01 86.7% 71.6%
3520738 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.54 46.0 3.82e-01 91.1% 67.1%
3824276 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.54 42.0 3.41e-01 88.9% 42.2%
4324547 544.1.1.2 alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › SRA1 0.52 38.0 3.63e-01 76.7% 97.1%
D4 medium residues 244-349
PDB
Domain cluster: representative
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.69 49.0 5.33e-01 74.5% 94.3%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 48.0 3.84e-01 74.5% 83.3%
1u00A02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.67 44.0 4.62e-01 75.5% 74.0%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 50.0 4.65e-01 85.8% 65.7%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.64 46.0 3.89e-01 75.5% 56.0%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 45.0 4.40e-01 75.5% 76.9%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 45.0 4.36e-01 75.5% 70.8%
1st6A01 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.62 46.0 3.47e-01 78.3% 34.5%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 42.0 4.31e-01 75.5% 74.5%
1w33A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.60 49.0 4.12e-01 87.7% 77.9%
4pdyA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.60 48.0 3.78e-01 86.8% 76.4%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.60 47.0 4.15e-01 84.9% 57.8%
2l7nA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.58 51.0 4.39e-01 98.1% 98.2%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 46.0 4.44e-01 88.7% 76.5%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 44.0 4.18e-01 85.8% 67.7%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.58 44.0 4.24e-01 87.7% 72.3%
7s0rB01 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.56 38.0 4.24e-01 89.6% 97.4%
2kmfA01 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.56 38.0 3.95e-01 88.7% 74.5%
3ejnA03 1.20.120.840 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SusD-like, tetratrico peptide repeats domain 0.54 39.0 3.85e-01 81.1% 71.2%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 47.0 4.04e-01 100.0% 92.2%
2k3oA00 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.54 44.0 4.14e-01 89.6% 96.1%
1a7vA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.53 40.0 3.85e-01 81.1% 83.2%
1y8aA02 1.10.3870.10 Mainly Alpha › Orthogonal Bundle › AF1437-like domain fold › AF1437-like domain superfamily 0.53 41.0 4.02e-01 84.0% 83.6%
1s05A00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.52 39.0 3.69e-01 79.2% 88.4%
5x56B00 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.52 37.0 3.72e-01 88.7% 73.3%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.52 37.0 3.02e-01 75.5% 83.2%
2y1eA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.51 35.0 3.81e-01 84.9% 85.1%
3vkgA09 1.20.920.30 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.51 40.0 3.71e-01 86.8% 71.5%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3547209 192.15.1.204 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF2678 0.73 53.0 5.49e-01 75.5% 87.0%
3922271 4177.2.1.11 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ALIX_LYPXL_bnd 0.73 53.0 4.30e-01 75.5% 74.9%
3604077 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.70 51.0 4.60e-01 74.5% 62.1%
3440913 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.70 50.0 4.63e-01 74.5% 82.2%
3338586 632.1.1.12 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › GAUT_1 0.70 53.0 5.62e-01 88.7% 94.4%
3584539 192.17.1.6 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › CC2D1A-B_DM14 0.69 44.0 5.13e-01 82.1% 92.0%
4956241 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.68 46.0 5.22e-01 73.6% 96.0%
4582075 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.68 45.0 4.86e-01 74.5% 80.0%
3632789 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.68 49.0 3.96e-01 74.5% 62.1%
4066789 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.67 55.0 5.05e-01 86.8% 73.3%
5028219 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.67 47.0 5.01e-01 74.5% 84.4%
4952876 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.67 47.0 5.06e-01 73.6% 98.9%
3465921 611.2.1.2 alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) › Rx_N 0.67 54.0 4.99e-01 86.8% 83.0%
3642919 611.7.1.16 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › PUB2_N 0.65 51.0 4.71e-01 84.0% 78.5%
5036028 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.64 51.0 4.66e-01 86.8% 78.6%
3336322 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.64 50.0 4.64e-01 84.0% 80.0%
3641736 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.63 48.0 4.13e-01 79.2% 64.8%
3711619 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.62 44.0 4.00e-01 74.5% 58.0%
3980912 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.62 45.0 4.43e-01 89.6% 70.4%
4410216 5068.1.1.1 alpha bundles › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) › Cytochrom_B_C 0.62 50.0 4.95e-01 89.6% 90.3%
4220561 601.1.1.5 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CAS_C 0.61 47.0 4.45e-01 88.7% 68.2%
3413892 632.19.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A 0.61 48.0 4.63e-01 100.0% 75.8%
3267567 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 47.0 4.73e-01 88.7% 81.8%
3600607 192.23.1.0 alpha bundles › Long alpha-hairpin › DUF683 › DUF683 0.59 42.0 4.09e-01 72.6% 83.5%
5040635 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.59 42.0 4.15e-01 86.8% 68.7%
3183037 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.59 49.0 4.11e-01 92.5% 73.0%
3766955 192.7.1.17 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FAM186A-B_C 0.59 41.0 3.76e-01 72.6% 93.8%
3445405 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 45.0 4.37e-01 88.7% 73.3%
3974600 601.3.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.58 47.0 4.48e-01 89.6% 88.5%
4942623 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.58 45.0 3.71e-01 84.9% 55.6%
3419853 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.58 42.0 3.85e-01 75.5% 57.2%
3237222 101.1.4.4 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like › CUT 0.55 39.0 4.00e-01 73.6% 77.1%
4025790 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.53 39.0 3.64e-01 90.6% 61.5%
3786037 544.1.1.2 alpha bundles › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › Functional domain of the splicing factor Prp18 › SRA1 0.52 46.0 4.55e-01 100.0% 100.0%
3859555 601.19.1.1 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein 0.52 44.0 3.78e-01 97.2% 77.8%
3736340 622.1.1.7 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › DUF7607 0.51 41.0 4.06e-01 88.7% 82.6%
3289203 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.51 39.0 3.90e-01 90.6% 79.1%