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GWB1_scaffold_5_curated_closed_complete_prodigal-single.1__X__X__00451

Bact-Vir

GWB1_scaffold_5_curated_closed_complete_prodigal-single.1__X__X__00451

Identity

Kingdom:
phage

Quality

66.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 41-205
PDB
Domain cluster: representative
CATH (66)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 40.0 4.69e-01 85.5% 73.3%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.73 41.0 5.01e-01 84.8% 84.3%
4bemJ00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.72 50.0 4.90e-01 86.1% 64.6%
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.71 44.0 4.53e-01 83.6% 64.5%
3ay5A02 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.71 47.0 4.74e-01 87.3% 66.1%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 49.0 5.02e-01 87.9% 73.2%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.71 52.0 4.94e-01 87.3% 65.1%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.69 48.0 5.53e-01 100.0% 99.2%
1b68A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.69 55.0 5.96e-01 95.2% 100.0%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.69 38.0 4.51e-01 84.8% 78.1%
2bl2A00 1.20.120.610 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase 0.68 47.0 4.84e-01 87.9% 73.1%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 50.0 5.21e-01 99.4% 81.8%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.68 45.0 4.94e-01 94.5% 81.6%
4wpcA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 57.0 4.67e-01 88.5% 79.5%
8hk0C01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 43.0 4.51e-01 86.1% 70.7%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.66 51.0 5.48e-01 87.9% 94.4%
8cdaB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.66 47.0 4.81e-01 83.6% 74.8%
2e87A01 1.20.120.1190 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 56.0 5.67e-01 98.8% 91.9%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.65 51.0 5.45e-01 87.9% 95.7%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 54.0 4.73e-01 87.9% 78.1%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 40.0 4.33e-01 86.1% 70.6%
3g9gA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 55.0 4.78e-01 90.9% 83.2%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.65 41.0 4.98e-01 88.5% 97.2%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 40.0 4.73e-01 87.9% 93.5%
5af7B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 41.0 4.32e-01 86.7% 70.9%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.64 58.0 5.61e-01 100.0% 91.5%
1qdbA02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 39.0 4.15e-01 87.9% 68.5%
4doyA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 46.0 4.48e-01 86.1% 67.2%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 53.0 5.12e-01 88.5% 93.9%
3l39A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 47.0 4.41e-01 100.0% 63.5%
1wdzA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 52.0 4.67e-01 88.5% 90.5%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 39.0 4.12e-01 87.9% 69.2%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 48.0 5.06e-01 100.0% 93.0%
1f1mA00 1.20.120.240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 0.62 50.0 5.08e-01 100.0% 87.0%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 53.0 4.47e-01 90.9% 86.1%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.61 41.0 4.32e-01 87.3% 74.2%
4im0A04 1.20.1270.420 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 50.0 4.45e-01 87.9% 83.6%
1gvnA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.60 33.0 4.19e-01 84.8% 96.6%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.60 40.0 3.58e-01 88.5% 48.9%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.60 44.0 4.67e-01 100.0% 85.6%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 49.0 4.43e-01 86.1% 88.6%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.59 43.0 4.72e-01 100.0% 91.7%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.59 51.0 5.19e-01 100.0% 94.5%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.59 49.0 4.65e-01 87.3% 94.8%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.59 47.0 4.89e-01 100.0% 91.5%
2l81A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.59 50.0 4.93e-01 100.0% 85.8%
5d91A02 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.58 41.0 3.90e-01 100.0% 60.1%
3ljbA00 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.58 53.0 4.80e-01 99.4% 81.7%
1n5uA01 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.57 30.0 3.67e-01 88.5% 78.6%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 50.0 4.27e-01 95.2% 80.8%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 48.0 4.20e-01 89.7% 83.7%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.56 43.0 4.42e-01 100.0% 85.2%
5gl7A01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.56 39.0 3.96e-01 94.5% 70.5%
4akgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.56 43.0 4.37e-01 90.3% 79.8%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.55 36.0 4.26e-01 74.5% 100.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.54 35.0 4.29e-01 97.6% 100.0%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.54 34.0 4.10e-01 88.5% 100.0%
6qumA04 1.10.1140.10 Mainly Alpha › Orthogonal Bundle › Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3 › Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3 0.54 33.0 3.46e-01 90.3% 64.4%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 49.0 4.15e-01 100.0% 99.3%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.52 36.0 4.06e-01 100.0% 94.3%
1q90B00 1.20.810.10 Mainly Alpha › Up-down Bundle › Cytochrome Bc1 Complex; Chain C › Cytochrome Bc1 Complex; Chain C 0.51 46.0 4.30e-01 99.4% 89.6%
1w33A00 1.10.3160.10 Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 0.51 42.0 4.15e-01 87.9% 86.2%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 44.0 4.02e-01 98.8% 69.2%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.51 44.0 4.44e-01 98.8% 92.2%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 40.0 4.11e-01 81.8% 90.6%
3frrA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.50 39.0 3.76e-01 81.2% 79.6%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3764834 601.1.2.2 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › I_LWEQ 0.75 54.0 5.16e-01 86.7% 63.7%
3270023 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.69 65.0 5.57e-01 100.0% 89.6%
3533377 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.68 47.0 4.57e-01 87.9% 63.3%
3617266 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.68 47.0 5.37e-01 87.9% 95.8%
3415295 4177.1.1.38 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin 0.68 55.0 5.81e-01 87.3% 94.0%
3515526 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.67 42.0 4.64e-01 86.1% 76.3%
3720250 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.67 42.0 4.54e-01 83.6% 72.7%
3940171 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.66 42.0 4.57e-01 88.5% 75.7%
3511227 601.15.1.2 alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_C 0.66 61.0 5.79e-01 100.0% 95.3%
3699787 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.65 55.0 4.79e-01 87.9% 90.0%
3887645 633.21.1.10 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL 0.65 38.0 4.25e-01 83.6% 73.1%
3411249 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.64 38.0 4.23e-01 83.6% 73.1%
3596769 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.64 39.0 4.20e-01 84.8% 69.0%
3995514 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.64 40.0 4.29e-01 86.1% 71.0%
3385045 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 48.0 5.32e-01 87.9% 100.0%
3709425 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.64 53.0 5.08e-01 87.3% 85.4%
5036028 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.64 45.0 4.77e-01 92.7% 82.8%
3550685 4177.1.1.38 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin 0.63 53.0 5.22e-01 87.9% 88.0%
3395314 601.15.1.0 alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) 0.63 54.0 5.55e-01 97.6% 96.8%
3662019 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 46.0 4.88e-01 87.9% 85.5%
3506288 4177.1.1.6 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg 0.63 52.0 4.80e-01 87.9% 88.3%
3287060 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.63 53.0 4.64e-01 88.5% 76.2%
5031101 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.63 43.0 4.19e-01 82.4% 63.3%
4575614 5045.1.1.1 alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.62 57.0 4.92e-01 100.0% 68.1%
3614798 207.1.1.45 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_4,LRR_8 0.62 52.0 3.24e-01 87.9% 16.9%
3454282 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 57.0 5.66e-01 100.0% 100.0%
3649819 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.62 45.0 5.07e-01 88.5% 100.0%
2596506 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 53.0 5.48e-01 97.6% 98.7%
3285241 192.29.1.52 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy 0.61 53.0 5.33e-01 98.8% 93.3%
3509261 601.15.1.2 alpha bundles › Four-helical up-and-down bundle › Proteasome activator reg(alpha) › Proteasome activator reg(alpha) › PA28_C 0.61 55.0 5.09e-01 100.0% 93.5%
3557360 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.61 56.0 4.68e-01 100.0% 85.7%
3442053 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.61 56.0 5.23e-01 100.0% 96.0%
4665474 4177.2.1.4 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ATG17_like 0.61 55.0 4.75e-01 99.4% 96.1%
3610928 633.6.1.0 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.60 45.0 4.44e-01 83.6% 71.1%
3805780 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.60 50.0 4.48e-01 87.9% 81.3%
3605419 1189.1.1.3 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › GARP 0.60 50.0 4.63e-01 87.3% 90.7%
3880326 4177.2.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain 0.60 55.0 4.57e-01 100.0% 89.7%
3459699 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.60 40.0 4.15e-01 84.2% 71.6%
4012210 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.60 40.0 4.18e-01 85.5% 72.7%
3573035 109.4.1.3370 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PL48 0.60 42.0 4.57e-01 70.9% 96.3%
3339348 606.1.1.12 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Rx_N 0.60 44.0 4.83e-01 86.7% 96.2%
3601571 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.60 42.0 4.45e-01 85.5% 81.4%
3241396 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.59 43.0 4.41e-01 86.7% 78.1%
3853126 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 52.0 4.31e-01 95.2% 89.7%
3900559 148.1.3.293 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › FAP206 0.59 48.0 3.87e-01 86.1% 48.6%
4059733 4177.1.1.66 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › ATG17_like 0.59 49.0 4.43e-01 87.9% 92.7%
4625331 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.59 51.0 4.75e-01 94.5% 91.4%
3419627 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.59 46.0 4.83e-01 98.2% 91.3%
3380500 192.29.1.34 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF677 0.58 53.0 4.89e-01 98.8% 96.2%
3298761 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.58 53.0 4.72e-01 100.0% 96.7%
3739409 3285.1.1.0 alpha duplicates or obligate multimers › Alix V domain › Alix V domain › Alix V domain 0.58 48.0 4.51e-01 87.9% 83.5%
3810540 3684.1.1.10 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 0.58 52.0 4.90e-01 99.4% 98.5%
4943286 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.58 39.0 4.15e-01 92.1% 77.0%
3742353 633.23.1.9 alpha bundles › Bromodomain-like › Claudin › Claudin › SUR7 0.58 48.0 4.29e-01 87.9% 78.9%
3613274 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.58 51.0 4.67e-01 96.4% 100.0%
5048496 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 41.0 3.79e-01 72.1% 86.8%
3730038 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.57 41.0 4.44e-01 87.9% 87.9%
3922271 4177.2.1.11 alpha duplicates or obligate multimers › BAR/IMD domain-like › Inhibitor of kappaB kinase beta dimerization domain › Inhibitor of kappaB kinase beta dimerization domain › ALIX_LYPXL_bnd 0.57 47.0 4.48e-01 87.9% 82.1%
3265477 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.57 47.0 4.28e-01 87.9% 79.5%
4944388 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.57 50.0 4.89e-01 100.0% 88.3%
3651361 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.57 52.0 4.67e-01 100.0% 93.0%
3297976 3758.1.1.31 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › DUF677 0.56 51.0 4.14e-01 100.0% 84.4%
4928363 150.1.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ferritin 0.56 39.0 4.40e-01 87.3% 92.9%
5037413 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 44.0 4.49e-01 88.5% 83.6%
4959549 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.56 48.0 4.60e-01 100.0% 80.5%
3506533 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.56 50.0 4.95e-01 98.2% 100.0%
3801176 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 38.0 3.84e-01 83.0% 68.5%
3675187 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.55 45.0 4.39e-01 89.1% 77.3%
3172328 4177.1.1.97 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PF30147 0.55 47.0 4.04e-01 90.9% 69.6%
3944917 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 34.0 3.04e-01 100.0% 44.4%
3194491 3755.3.1.358 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ATG17_like 0.55 45.0 3.25e-01 87.9% 39.2%
3628290 150.1.1.24 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Prominin 0.54 47.0 3.99e-01 93.3% 60.4%
3698277 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.54 44.0 4.51e-01 87.9% 89.4%
3920610 633.23.1.2 alpha bundles › Bromodomain-like › Claudin › Claudin › GSG-1 0.54 45.0 4.32e-01 87.3% 78.9%
3288367 150.8.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE 0.53 47.0 4.71e-01 95.8% 98.8%
4996693 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 50.0 4.49e-01 100.0% 94.5%
3812158 192.29.1.115 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF599 0.52 46.0 4.18e-01 95.8% 87.7%
3715011 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.52 41.0 3.90e-01 100.0% 69.7%
3936091 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.52 45.0 4.03e-01 96.4% 70.6%
3676423 174.1.1.72 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2985 0.51 42.0 3.97e-01 85.5% 76.9%
3377710 4323.1.1.8 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › NET2A 0.51 37.0 3.90e-01 96.4% 82.0%
D2 high residues 236-396
PDB
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1pwuA04 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.79 72.0 6.37e-01 95.0% 83.7%
7jv7B01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 37.0 3.90e-01 87.0% 67.8%
5zzjA02 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 42.0 3.34e-01 73.3% 55.9%
3p5pA03 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 42.0 3.37e-01 75.2% 56.4%
1n1bB02 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.56 40.0 3.25e-01 73.3% 56.8%
3hibA01 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.56 36.0 4.02e-01 81.4% 86.4%
4f92B10 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.55 36.0 3.78e-01 91.3% 72.7%
1ichA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.54 27.0 3.50e-01 78.9% 86.2%
3g0tA02 6.10.120.10 Special › Helix non-globular › 434 Repressor (Amino-terminal Domain) › Bacterial aspartate aminotransferase, helical domain 0.53 20.0 2.89e-01 84.5% 72.9%
1hbgA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 31.0 3.28e-01 88.2% 66.0%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4026483 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.81 73.0 6.46e-01 94.4% 78.6%
4951424 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.77 69.0 6.45e-01 95.0% 82.1%
4013081 2498.1.1.36 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › WLM 0.71 49.0 5.27e-01 82.6% 80.7%
4929424 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.68 42.0 5.22e-01 79.5% 100.0%
4948728 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.62 32.0 4.13e-01 77.0% 85.3%
4261757 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.62 54.0 4.68e-01 94.4% 76.4%
4031195 2498.1.1.50 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Zn_peptidase_2 0.61 44.0 4.51e-01 76.4% 76.1%
3288863 2498.1.1.63 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Zn_peptidase 0.61 51.0 4.62e-01 88.2% 93.4%
3598088 101.1.10.0 alpha arrays › HTH › HTH › Cyclin-like 0.60 35.0 3.86e-01 84.5% 70.0%
3291642 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.59 49.0 4.48e-01 87.0% 89.3%
4326930 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.58 43.0 3.29e-01 75.2% 51.5%
3328026 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.58 42.0 3.35e-01 75.2% 55.0%
5054592 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.57 37.0 4.44e-01 74.5% 96.4%
3815016 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.56 41.0 3.23e-01 74.5% 54.5%
3890179 7061.1.1.1 few secondary structure elements › VWF C8-3 module › VWF C8-3 module › VWF C8-3 module › C8 0.56 30.0 3.89e-01 82.0% 95.3%
4060633 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.56 41.0 3.28e-01 75.2% 56.1%
4430787 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.55 41.0 3.18e-01 76.4% 52.9%
3668440 141.1.1.0 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases 0.54 39.0 3.28e-01 75.2% 52.9%
4497406 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.53 39.0 3.07e-01 74.5% 54.1%
3453441 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.53 39.0 3.11e-01 76.4% 56.6%
3425929 606.1.1.0 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain 0.52 30.0 3.38e-01 99.4% 72.5%
3462781 141.1.1.4 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C 0.52 38.0 3.03e-01 75.2% 54.5%
D3 high residues 494-557
PDB
Domain cluster: representative
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4o5lL02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.71 50.0 4.20e-01 73.4% 74.0%
5dmyA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.71 59.0 4.73e-01 90.6% 78.5%
2qh9A00 3.30.2170.10 Alpha Beta › 2-Layer Sandwich › archaeoglobus fulgidus dsm 4304 fold › archaeoglobus fulgidus dsm 4304 superfamily 0.71 48.0 3.41e-01 70.3% 39.9%
3fn9A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.70 58.0 4.71e-01 90.6% 76.7%
4cu7A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.70 58.0 4.69e-01 90.6% 78.5%
2ownA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.70 56.0 3.69e-01 87.5% 89.5%
2pn5A03 2.60.40.1940 Mainly Beta › Sandwich › Immunoglobulin-like › 0.70 47.0 3.99e-01 70.3% 67.6%
7rskA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.70 56.0 4.67e-01 87.5% 81.7%
3g0kA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.70 47.0 3.71e-01 75.0% 35.2%
4exrA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.69 48.0 4.43e-01 92.2% 56.8%
4fx9A03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.69 48.0 4.01e-01 73.4% 46.0%
3gm8A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.69 57.0 4.83e-01 90.6% 78.1%
1nhpA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.69 48.0 4.02e-01 73.4% 46.9%
3cgbA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.69 49.0 4.09e-01 75.0% 47.3%
5z1aA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.68 56.0 4.60e-01 90.6% 76.3%
1yqzA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.68 47.0 3.98e-01 73.4% 46.3%
2vzsA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.68 55.0 4.60e-01 89.1% 80.0%
2cduA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.68 48.0 3.98e-01 75.0% 46.9%
1wftA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 53.0 4.58e-01 87.5% 85.6%
2retA00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.67 57.0 5.21e-01 93.8% 79.8%
2hx5A00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.65 55.0 4.24e-01 92.2% 88.8%
4fzqA00 2.20.230.10 Mainly Beta › Single Sheet › Resuscitation-promoting factor rpfb fold › Resuscitation-promoting factor rpfb. 0.65 46.0 4.36e-01 76.6% 87.3%
1wznA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.65 47.0 4.96e-01 84.4% 87.5%
3cjyA00 2.40.160.210 Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain 0.65 51.0 3.41e-01 85.9% 41.9%
4jklA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.64 53.0 4.67e-01 90.6% 76.8%
1wfnA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.64 52.0 4.69e-01 89.1% 86.4%
1tuhA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.63 44.0 3.51e-01 81.2% 35.9%
3lqmA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 52.0 4.71e-01 93.8% 81.1%
4jzjC02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 52.0 4.42e-01 90.6% 78.8%
3lb6D02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 54.0 4.73e-01 93.8% 82.6%
3s9dD01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 51.0 4.45e-01 89.1% 82.3%
3d6xB00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.62 50.0 3.92e-01 89.1% 95.7%
6xaxA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 50.0 4.54e-01 87.5% 84.7%
2dn7A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 52.0 4.46e-01 95.3% 72.9%
1vw4502 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.62 47.0 4.20e-01 85.9% 57.6%
4fvkA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.62 48.0 2.99e-01 84.4% 29.2%
3uc2A00 2.60.40.3340 Mainly Beta › Sandwich › Immunoglobulin-like › Domain of unknown function DUF4426 0.62 51.0 4.15e-01 92.2% 95.2%
5eoxB03 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 44.0 3.50e-01 76.6% 38.3%
5fmvA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 48.0 4.44e-01 87.5% 84.5%
7sf2A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 49.0 4.36e-01 89.1% 84.9%
1lwrA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 51.0 4.49e-01 95.3% 80.2%
1lqvB00 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.61 48.0 3.66e-01 92.2% 61.8%
2v5yA05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 51.0 4.46e-01 95.3% 83.5%
4ywzB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.60 52.0 3.99e-01 96.9% 86.3%
2dleA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 47.0 4.33e-01 87.5% 81.4%
2e5aA02 3.30.390.50 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain 0.60 38.0 3.43e-01 79.7% 45.2%
4hrzB00 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 45.0 3.72e-01 84.4% 48.0%
2kzxA00 3.90.1010.20 Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › 0.59 42.0 3.38e-01 76.6% 45.0%
4hrvA00 3.40.50.10610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ABC-type transport auxiliary lipoprotein component 0.58 48.0 3.73e-01 90.6% 67.6%
1avgI00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.58 41.0 3.17e-01 73.4% 78.2%
5irbA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 49.0 4.19e-01 95.3% 76.0%
1g4wR02 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.57 44.0 3.12e-01 87.5% 40.7%
2ebmA00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.56 42.0 3.45e-01 82.8% 43.8%
3nqzA01 3.10.450.490 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 41.0 3.77e-01 89.1% 57.1%
2gtlM02 2.40.128.620 Mainly Beta › Beta Barrel › Lipocalin › 0.56 42.0 3.22e-01 84.4% 37.3%
6cxhA03 2.60.40.1580 Mainly Beta › Sandwich › Immunoglobulin-like › Particulate methane monooxygenase, b subunit. Chain: A, domain 3 0.56 44.0 3.55e-01 90.6% 81.6%
1sr9A02 3.30.160.270 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Alpha-isopropylmalate synthase LeuA, regulatory domain 0.55 42.0 3.21e-01 87.5% 33.5%
4k3yC00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.55 47.0 2.96e-01 95.3% 31.8%
1rm6B02 3.30.390.50 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain 0.55 38.0 3.26e-01 73.4% 79.4%
3t0pA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.54 42.0 3.01e-01 90.6% 28.0%
2ifgA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 42.0 3.86e-01 89.1% 78.9%
4d8pB01 3.10.320.10 Alpha Beta › Roll › Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 › Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 0.54 44.0 3.83e-01 92.2% 88.2%
2cc3A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.54 43.0 3.40e-01 90.6% 63.9%
4kz1A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.54 42.0 3.46e-01 92.2% 67.4%
1lshA04 2.20.80.10 Mainly Beta › Single Sheet › Lipovitellin-phosvitin complex, chain A, domain 4 › Lipovitellin-phosvitin complex, chain A, domain 4 0.53 40.0 2.78e-01 85.9% 37.1%
7jvhC01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.52 41.0 2.68e-01 93.8% 17.7%
1g19A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 39.0 2.82e-01 87.5% 78.6%
4ibnA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 35.0 2.63e-01 73.4% 80.9%
5h9kA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 43.0 3.36e-01 98.4% 52.6%
3ehcB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 41.0 3.43e-01 95.3% 50.0%
6nhsA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.51 36.0 2.51e-01 85.9% 20.1%
1lyvA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.51 42.0 2.85e-01 98.4% 36.7%
6krwA01 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.50 42.0 2.79e-01 98.4% 35.4%
3eo5A01 2.20.230.10 Mainly Beta › Single Sheet › Resuscitation-promoting factor rpfb fold › Resuscitation-promoting factor rpfb. 0.50 39.0 3.59e-01 89.1% 79.5%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4969580 2484.1.1.43 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 0.79 50.0 3.36e-01 70.3% 18.6%
3512065 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 45.0 4.53e-01 71.9% 58.5%
4557706 2484.1.1.174 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.75 47.0 3.58e-01 70.3% 28.3%
4289516 2484.1.1.223 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27036 0.75 50.0 3.42e-01 71.9% 21.0%
4505130 2484.1.1.174 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.73 48.0 3.84e-01 76.6% 34.4%
5005118 244.2.1.1 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim 0.73 50.0 4.00e-01 71.9% 39.1%
5031294 2484.1.1.22 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 0.72 49.0 3.45e-01 70.3% 40.5%
3263815 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.72 56.0 5.01e-01 87.5% 60.0%
4131273 11.1.1.14 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 0.71 58.0 4.86e-01 87.5% 81.0%
5079352 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.71 59.0 4.71e-01 90.6% 68.0%
4954572 2484.1.1.174 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.70 45.0 3.68e-01 70.3% 35.0%
3725895 246.2.1.8 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › PhoD 0.69 59.0 3.60e-01 93.8% 37.9%
4989982 244.2.1.1 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Pyr_redox_dim 0.69 49.0 3.96e-01 75.0% 41.6%
4968129 11.1.1.1424 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF7490 0.69 56.0 4.74e-01 89.1% 81.0%
3877924 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.69 50.0 4.54e-01 76.6% 61.2%
5002134 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.68 55.0 4.85e-01 85.9% 87.8%
5038729 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.68 55.0 4.65e-01 87.5% 75.2%
5038844 330.2.1.0 a+b two layers › dsRBD-like › Ribosome binding protein Y (YfiA homologue) › Ribosome binding protein Y (YfiA homologue) 0.68 54.0 5.00e-01 85.9% 71.2%
3507047 244.4.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › Ni-Fe binding domain in nickel-iron hydrogenase large subunit › Ni-Fe binding domain in nickel-iron hydrogenase large subunit 0.68 55.0 4.77e-01 89.1% 87.0%
5069241 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.68 46.0 3.83e-01 70.3% 66.4%
3240576 11.1.1.14 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 0.68 54.0 4.81e-01 85.9% 84.4%
4469458 11.1.1.14 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Glyco_hydro_2 0.68 54.0 4.40e-01 85.9% 79.1%
3617706 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.67 51.0 4.43e-01 82.8% 100.0%
4940463 274.1.1.0 a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.67 54.0 4.21e-01 87.5% 60.0%
4982423 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.67 54.0 3.66e-01 92.2% 78.0%
4357423 11.1.1.21 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Tissue_fac 0.66 54.0 4.54e-01 90.6% 75.5%
5051830 11.1.1.236 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Mannosidase_ig 0.66 53.0 4.67e-01 89.1% 93.7%
3439529 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.66 45.0 3.34e-01 70.3% 28.5%
4333153 2484.1.1.174 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › UvrC_RNaseH 0.66 49.0 3.83e-01 78.1% 40.8%
3592050 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.66 50.0 4.00e-01 84.4% 97.8%
4989642 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.65 46.0 2.93e-01 75.0% 15.1%
3468117 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.65 46.0 3.36e-01 75.0% 38.9%
3843400 11.1.1.127 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › IL6Ra-bind 0.65 53.0 4.28e-01 89.1% 82.5%
3840019 2484.1.1.261 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PF27038 0.64 43.0 3.34e-01 76.6% 29.3%
4042443 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 51.0 4.51e-01 87.5% 80.0%
4950045 7089.1.1.0 a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD 0.64 49.0 4.54e-01 87.5% 63.5%
4960807 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 51.0 4.57e-01 87.5% 80.0%
3452851 2484.1.1.67 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.64 43.0 3.41e-01 71.9% 33.3%
3277546 4210.1.1.1 a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.64 51.0 4.19e-01 89.1% 47.5%
4446877 2484.1.1.43 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 0.63 53.0 3.45e-01 90.6% 37.4%
3286883 2003.1.5.67 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.63 52.0 3.51e-01 92.2% 83.3%
4939973 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 48.0 3.97e-01 85.9% 84.0%
3186839 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.63 55.0 3.38e-01 95.3% 22.7%
3228242 4210.1.1.1 a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.63 48.0 4.15e-01 90.6% 53.0%
5079533 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.62 53.0 3.61e-01 92.2% 79.1%
4956532 2484.1.1.22 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF99 0.62 47.0 3.41e-01 81.2% 42.2%
4974362 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.62 51.0 3.40e-01 89.1% 80.6%
3706741 5.1.3.28 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › BNR_3 0.62 52.0 3.58e-01 96.9% 77.6%
4938125 896.1.1.0 a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.62 51.0 4.64e-01 90.6% 71.8%
3602117 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 51.0 4.34e-01 90.6% 76.2%
4025315 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.62 51.0 4.25e-01 90.6% 66.4%
3490071 71.2.1.4 beta meanders › Lipoprotein localization factors LolAB › PA1994-like › PA1994-like › CATIP_N 0.62 47.0 3.24e-01 84.4% 27.7%
4045675 223.1.1.81 a+b three layers › Profilin-like › sensor domains › sensor domains › Cache_WalK 0.60 52.0 3.68e-01 96.9% 63.5%
4653627 4252.1.1.3 beta barrels › AttH-like › AttH-like › AttH-like › DA_C 0.60 48.0 3.61e-01 89.1% 68.5%
3924939 4210.1.1.1 a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.60 46.0 3.85e-01 89.1% 47.0%
5009292 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.60 49.0 3.32e-01 92.2% 80.8%
4587404 222.2.1.0 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Insertion domain in thioesterase › Insertion domain in thioesterase 0.59 48.0 4.16e-01 89.1% 79.0%
4505972 323.1.1.3 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.59 47.0 2.98e-01 85.9% 18.4%
5079226 2484.1.1.67 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.59 40.0 2.85e-01 70.3% 23.4%
3795283 708.1.1.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.59 49.0 4.26e-01 92.2% 96.0%
3708039 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 47.0 4.20e-01 90.6% 80.0%
5021465 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 43.0 2.82e-01 79.7% 72.7%
3992448 708.1.1.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.57 50.0 4.00e-01 100.0% 97.0%
4947855 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 48.0 2.95e-01 96.9% 80.5%
3514681 7089.1.1.0 a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD 0.57 41.0 4.19e-01 87.5% 83.3%
3269706 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 42.0 3.94e-01 81.2% 97.5%
5016827 5090.1.1.11 beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › S_layer_N 0.56 45.0 3.69e-01 87.5% 73.1%
3177409 330.1.1.13 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Mgm101p 0.56 44.0 3.37e-01 90.6% 35.2%
3587998 243.1.1.102 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF28180 0.53 43.0 3.74e-01 92.2% 77.1%
3221443 5.1.4.61 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PAN2_N 0.53 44.0 2.79e-01 93.8% 82.6%
4992208 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.52 42.0 2.87e-01 92.2% 76.8%
4961790 2003.1.5.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.52 38.0 2.72e-01 82.8% 84.6%