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GWB1_scaffold_combined_curated_closed_complete_prodigal-single.1__X__X__00433
Bact-VirGWB1_scaffold_combined_curated_closed_complete_prodigal-single.1__X__X__00433
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-59
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1nriA00 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.63 | 49.0 | 3.21e-01 | 90.9% | 19.4% |
D2
high
residues 65-230
Domain cluster:
rep: AP018399.1__BBA65417.1__X__00269__D45-211
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.73 | 58.0 | 6.21e-01 | 81.9% | 98.6% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.62 | 43.0 | 4.92e-01 | 79.5% | 99.1% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 53.0 | 4.63e-01 | 94.0% | 90.5% |
| 4hyjA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 53.0 | 4.74e-01 | 94.6% | 94.5% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.60 | 41.0 | 4.76e-01 | 73.5% | 98.3% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.60 | 51.0 | 5.31e-01 | 95.2% | 99.3% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 41.0 | 4.71e-01 | 75.3% | 99.1% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 52.0 | 4.76e-01 | 98.2% | 97.8% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.57 | 35.0 | 3.73e-01 | 88.0% | 68.2% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 42.0 | 4.58e-01 | 85.5% | 97.7% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 42.0 | 4.66e-01 | 78.3% | 100.0% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 44.0 | 4.06e-01 | 83.7% | 67.6% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 40.0 | 4.54e-01 | 80.1% | 99.2% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.56 | 43.0 | 4.15e-01 | 81.3% | 89.4% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.55 | 42.0 | 4.01e-01 | 80.1% | 81.6% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.55 | 41.0 | 4.24e-01 | 81.3% | 83.1% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 45.0 | 3.76e-01 | 92.2% | 90.5% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.53 | 43.0 | 3.98e-01 | 86.7% | 80.6% |
| 6ko5A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 45.0 | 3.76e-01 | 91.6% | 93.5% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.53 | 42.0 | 4.07e-01 | 83.7% | 76.5% |
| 4qgpB00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.53 | 28.0 | 3.36e-01 | 89.8% | 77.6% |
| 3lwjA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 37.0 | 3.53e-01 | 72.3% | 61.1% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 39.0 | 3.72e-01 | 78.3% | 100.0% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.52 | 35.0 | 3.88e-01 | 83.1% | 85.0% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 40.0 | 3.69e-01 | 79.5% | 97.6% |
| 3pivA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 38.0 | 3.93e-01 | 77.1% | 100.0% |
| 3swhA01 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.51 | 39.0 | 3.92e-01 | 79.5% | 83.6% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.50 | 37.0 | 3.76e-01 | 75.3% | 90.9% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.50 | 43.0 | 4.05e-01 | 96.4% | 83.4% |
| 6t0bc02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.50 | 42.0 | 4.03e-01 | 90.4% | 87.4% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3509220 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.73 | 36.0 | 3.14e-01 | 84.9% | 32.2% |
| 3495538 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.65 | 39.0 | 4.03e-01 | 92.8% | 61.9% |
| 3238390 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.65 | 52.0 | 5.19e-01 | 84.3% | 91.2% |
| 4411923 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.65 | 58.0 | 5.37e-01 | 97.6% | 78.1% |
| 3852378 | 4177.1.1.61 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PLC-beta_C | 0.64 | 35.0 | 2.96e-01 | 88.0% | 33.1% |
| 3785363 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.63 | 37.0 | 4.59e-01 | 97.0% | 94.0% |
| 3716232 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.63 | 50.0 | 5.20e-01 | 83.7% | 99.3% |
| 3191897 | 601.1.1.150 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF7783 | 0.62 | 46.0 | 5.12e-01 | 82.5% | 96.9% |
| 3390092 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 46.0 | 5.15e-01 | 77.1% | 100.0% |
| 3039953 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.61 | 55.0 | 4.74e-01 | 96.4% | 91.4% |
| 3804981 | 192.29.1.7 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › TMEM192 | 0.60 | 48.0 | 4.96e-01 | 83.1% | 90.3% |
| 3396795 | 601.1.1.43 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Serendipity_A | 0.58 | 39.0 | 4.57e-01 | 77.7% | 100.0% |
| 5010292 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.57 | 45.0 | 4.72e-01 | 81.3% | 94.7% |
| 3415815 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 46.0 | 4.62e-01 | 84.3% | 85.5% |
| 3871867 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.57 | 41.0 | 4.40e-01 | 74.1% | 90.0% |
| 5036796 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 45.0 | 4.80e-01 | 83.1% | 99.3% |
| 3880738 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.56 | 42.0 | 4.48e-01 | 85.5% | 91.4% |
| 4674585 | 5039.1.1.1 ↗ | alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › COX3 | 0.56 | 44.0 | 4.13e-01 | 80.7% | 71.0% |
| 4012236 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.56 | 37.0 | 3.79e-01 | 95.8% | 68.8% |
| 3258488 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 31.0 | 3.81e-01 | 78.3% | 88.0% |
| 3970257 | 5069.1.1.5 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_II | 0.55 | 41.0 | 3.99e-01 | 75.9% | 71.1% |
| 3624615 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.55 | 34.0 | 3.71e-01 | 72.3% | 74.1% |
| 3444302 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.55 | 36.0 | 3.97e-01 | 92.8% | 81.5% |
| 3684868 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.55 | 36.0 | 3.95e-01 | 94.0% | 80.0% |
| 3270478 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.54 | 28.0 | 3.43e-01 | 94.0% | 77.1% |
| 4945412 | 601.14.1.13 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › PAS_10 | 0.54 | 44.0 | 4.26e-01 | 86.7% | 83.2% |
| 3936929 | 5057.1.1.13 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Strabismus | 0.54 | 38.0 | 4.05e-01 | 72.9% | 87.3% |
| 4013484 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.54 | 39.0 | 3.71e-01 | 75.3% | 93.2% |
| 3263327 | 192.29.1.52 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy | 0.53 | 41.0 | 4.34e-01 | 83.1% | 90.7% |
| 3204692 | 5001.1.1.39 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › RTA1 | 0.53 | 47.0 | 3.99e-01 | 94.6% | 97.0% |
| 3565220 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.53 | 36.0 | 3.84e-01 | 74.7% | 77.2% |
| 2703780 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.53 | 42.0 | 4.20e-01 | 84.3% | 94.3% |
| 3424503 | 192.29.1.46 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF1110 | 0.53 | 42.0 | 4.07e-01 | 83.1% | 91.9% |
| 3467780 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.52 | 39.0 | 4.10e-01 | 96.4% | 86.0% |
| 4989670 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.52 | 47.0 | 4.36e-01 | 97.6% | 81.4% |
| 3859664 | 5059.1.1.3 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT | 0.52 | 43.0 | 3.52e-01 | 89.2% | 57.8% |
| 3186481 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 40.0 | 4.09e-01 | 80.7% | 87.5% |
| 3272245 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.51 | 37.0 | 3.20e-01 | 74.1% | 63.3% |
| 3845930 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.51 | 33.0 | 3.52e-01 | 72.9% | 74.3% |
| 1866828 | 601.4.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH | 0.51 | 42.0 | 4.22e-01 | 86.1% | 95.2% |
| 4008078 | 601.4.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH | 0.51 | 41.0 | 4.06e-01 | 86.1% | 80.6% |
| 4024030 | 192.29.1.104 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4149 | 0.51 | 38.0 | 3.58e-01 | 77.7% | 78.5% |