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G_protein-coupled_receptor-1

Euk-Vir

Elephant_endotheliotropic_herpesvirus_4

G_protein-coupled_receptor-1__YP_009179319__Elephant_endotheliotropic_herpesvirus_4__548914

Identity

Accession:
YP_009179319 ↗
Protein ID:
G_protein-coupled_receptor-1
Kingdom:
euk

Quality

66.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-110
PDB
Domain cluster: representative
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4mbsA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.87 72.0 4.88e-01 92.7% 27.5%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.75 57.0 5.15e-01 87.3% 59.9%
3ggyA00 1.20.1260.60 Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 0.74 63.0 5.19e-01 89.1% 85.5%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.72 49.0 5.02e-01 79.1% 71.7%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.72 55.0 5.04e-01 100.0% 62.2%
1jalA03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.71 45.0 5.12e-01 93.6% 86.4%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.70 47.0 4.87e-01 82.7% 73.5%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 59.0 4.33e-01 90.0% 81.5%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 48.0 4.89e-01 80.9% 73.4%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.68 51.0 5.00e-01 100.0% 73.1%
3rfyA02 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.67 46.0 4.73e-01 82.7% 73.8%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.66 51.0 4.70e-01 82.7% 79.6%
2wl8C00 1.20.120.900 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pex19, mPTS binding domain 0.65 50.0 5.09e-01 98.2% 81.7%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.65 56.0 4.37e-01 92.7% 79.3%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.65 49.0 4.88e-01 100.0% 77.0%
2c0uA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 50.0 4.37e-01 82.7% 60.4%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.64 51.0 4.29e-01 85.5% 91.0%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.64 57.0 4.38e-01 96.4% 84.5%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.64 32.0 3.56e-01 78.2% 59.1%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.64 51.0 4.75e-01 100.0% 69.3%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 54.0 4.57e-01 91.8% 91.7%
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.63 49.0 4.89e-01 100.0% 80.4%
3ddeB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.63 51.0 3.99e-01 86.4% 63.2%
1sj7C00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.63 52.0 4.55e-01 100.0% 59.6%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.63 52.0 4.40e-01 90.0% 94.6%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.63 48.0 4.76e-01 79.1% 78.6%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.62 56.0 4.50e-01 100.0% 50.7%
1otkA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 48.0 3.69e-01 82.7% 54.1%
4rm7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 47.0 4.36e-01 82.7% 66.9%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.61 46.0 3.92e-01 79.1% 56.6%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 45.0 4.81e-01 91.8% 92.6%
1cpqA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.60 51.0 4.91e-01 100.0% 79.8%
1xg2B00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.60 54.0 4.85e-01 98.2% 72.8%
4i1mB01 1.20.120.1700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.60 48.0 4.61e-01 100.0% 75.2%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 45.0 4.19e-01 80.0% 70.3%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.59 50.0 4.96e-01 100.0% 86.6%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.59 47.0 4.49e-01 85.5% 82.3%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 50.0 4.94e-01 100.0% 88.0%
1lm3B00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.59 46.0 4.71e-01 100.0% 87.7%
1cgnA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.59 49.0 4.75e-01 100.0% 81.5%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.59 50.0 4.59e-01 91.8% 88.8%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.58 38.0 4.54e-01 70.9% 98.6%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.58 49.0 4.73e-01 100.0% 79.8%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.57 41.0 4.31e-01 74.5% 99.0%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.57 49.0 4.18e-01 100.0% 58.3%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.56 51.0 4.26e-01 100.0% 72.9%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.56 48.0 4.39e-01 91.8% 90.0%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 41.0 3.96e-01 78.2% 68.0%
2q7rB00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.54 43.0 3.92e-01 85.5% 66.0%
3pt1A02 1.20.930.60 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › 0.54 42.0 4.11e-01 82.7% 94.2%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.52 39.0 3.73e-01 78.2% 91.5%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3571389 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.91 73.0 5.11e-01 97.3% 30.2%
3879274 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.89 77.0 6.08e-01 90.0% 48.8%
4174496 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.89 74.0 6.14e-01 95.5% 54.3%
4854872 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.88 71.0 5.73e-01 83.6% 47.9%
3993967 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.88 64.0 5.95e-01 75.5% 62.2%
4259017 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.88 75.0 5.62e-01 91.8% 40.8%
3770088 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.87 74.0 5.80e-01 95.5% 45.6%
3767125 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.87 77.0 5.29e-01 96.4% 30.7%
3878090 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.86 79.0 5.39e-01 100.0% 31.0%
3565644 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.82 76.0 5.27e-01 99.1% 34.2%
4422597 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.81 72.0 5.04e-01 95.5% 32.5%
3582594 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.79 70.0 5.50e-01 94.5% 48.4%
3413818 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.76 57.0 5.21e-01 89.1% 60.7%
3409829 604.1.1.16 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PEX11 0.75 68.0 5.43e-01 100.0% 93.0%
3828167 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.75 56.0 4.95e-01 82.7% 54.4%
3783473 601.1.2.136 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › SOG2 0.73 57.0 4.89e-01 81.8% 59.4%
3826980 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.73 54.0 4.71e-01 82.7% 52.5%
3509307 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 60.0 5.12e-01 91.8% 55.4%
3414605 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.73 54.0 5.02e-01 86.4% 63.0%
3998922 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.72 63.0 4.44e-01 96.4% 32.2%
3292478 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.72 59.0 5.11e-01 88.2% 74.7%
3360919 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.71 52.0 4.76e-01 83.6% 58.3%
3219345 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.71 64.0 4.60e-01 99.1% 71.7%
4090147 633.21.1.22 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › COPI_assoc 0.71 58.0 5.23e-01 90.0% 64.7%
3481289 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.70 59.0 5.49e-01 92.7% 73.3%
3219872 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.70 60.0 5.50e-01 100.0% 72.1%
3974204 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.70 55.0 5.36e-01 100.0% 76.7%
2878134 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.69 59.0 5.44e-01 100.0% 72.1%
3503770 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.69 54.0 4.93e-01 91.8% 62.8%
3246911 601.1.2.49 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PPP1R21_helical 0.69 62.0 4.99e-01 100.0% 88.8%
3804215 1025.1.1.0 alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain 0.69 52.0 5.44e-01 80.9% 86.0%
3814534 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 56.0 5.05e-01 87.3% 76.5%
3325695 192.29.1.171 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Sas10_Utp3 0.68 54.0 5.23e-01 86.4% 77.6%
3316910 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.68 56.0 4.99e-01 88.2% 77.4%
3495283 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.68 57.0 5.36e-01 93.6% 74.1%
3257764 192.29.1.171 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Sas10_Utp3 0.67 53.0 5.30e-01 85.5% 84.3%
3608572 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.67 56.0 4.60e-01 90.0% 69.0%
3230066 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.67 61.0 5.67e-01 100.0% 80.7%
3399076 150.1.1.94 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Sas10_Utp3 0.67 53.0 5.24e-01 86.4% 84.2%
3802240 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.66 53.0 5.53e-01 82.7% 92.0%
3222373 605.4.1.18 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 0.66 44.0 4.93e-01 77.3% 88.2%
3319537 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.66 53.0 4.73e-01 86.4% 72.1%
3829240 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 53.0 5.20e-01 86.4% 90.0%
3839810 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 54.0 4.97e-01 89.1% 77.1%
4033032 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.64 58.0 5.37e-01 100.0% 77.9%
4967728 5058.1.1.100 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PsiE 0.64 54.0 4.95e-01 91.8% 69.7%
4142133 133.1.1.7 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › PF28625 0.64 52.0 4.61e-01 94.5% 59.4%
5076088 5039.1.1.0 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like 0.64 58.0 5.42e-01 100.0% 81.5%
4983097 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.64 49.0 4.97e-01 90.9% 80.9%
3836689 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.64 51.0 4.63e-01 86.4% 74.0%
4024941 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.63 56.0 4.84e-01 100.0% 82.2%
3725890 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.63 57.0 5.49e-01 100.0% 88.8%
4370662 601.2.1.6 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Cytochrom_B562 0.63 47.0 4.93e-01 100.0% 85.9%
3668496 632.1.1.17 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Sas10_Utp3 0.63 50.0 5.24e-01 86.4% 95.0%
3379436 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.63 56.0 4.82e-01 98.2% 64.6%
3538067 633.10.1.15 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 0.63 47.0 5.07e-01 79.1% 100.0%
3423837 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.63 57.0 4.98e-01 98.2% 73.1%
3578008 601.1.2.100 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF31009 0.62 52.0 4.68e-01 96.4% 65.2%
3563670 3758.1.1.54 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › ApoL 0.62 44.0 4.81e-01 72.7% 100.0%
3633897 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 56.0 4.80e-01 100.0% 62.4%
3602410 604.1.1.235 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27233 0.62 46.0 3.57e-01 79.1% 79.2%
3806117 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.62 56.0 4.98e-01 98.2% 72.9%
3242888 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.62 49.0 4.63e-01 91.8% 69.6%
4019922 611.4.1.0 alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like 0.62 50.0 4.27e-01 86.4% 75.4%
3662200 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.62 56.0 4.95e-01 98.2% 74.8%
3172946 601.19.1.40 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › PF28954 0.61 46.0 3.93e-01 79.1% 66.1%
4988447 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.61 49.0 4.88e-01 85.5% 91.3%
3744108 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.61 47.0 4.34e-01 90.0% 62.8%
3442007 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.61 55.0 4.78e-01 98.2% 71.5%
3887929 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.61 49.0 4.80e-01 93.6% 80.8%
3551506 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.60 50.0 3.66e-01 90.0% 79.7%
4029442 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 53.0 4.07e-01 99.1% 71.2%
5007279 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.60 48.0 4.99e-01 85.5% 89.5%
3911777 633.10.1.15 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 0.60 47.0 4.45e-01 93.6% 69.6%
4014055 611.7.1.19 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › NACHT_N 0.60 48.0 4.32e-01 86.4% 67.7%
4946230 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.60 52.0 4.08e-01 95.5% 63.9%
3821611 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 52.0 4.42e-01 98.2% 67.8%
3664290 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.58 52.0 4.58e-01 98.2% 73.0%
3445666 601.1.2.74 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Rx_N 0.58 45.0 4.21e-01 80.9% 81.5%
3803125 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.58 51.0 4.36e-01 98.2% 69.8%
3432279 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.57 51.0 4.62e-01 98.2% 72.7%
2075013 601.2.1.2 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › 7tm_1,Cytochrom_B562 0.56 41.0 4.54e-01 82.7% 100.0%
D2 medium residues 162-306
PDB
Domain cluster: representative
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4hkrA00 1.20.140.140 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai 0.72 53.0 5.13e-01 87.6% 67.3%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.72 33.0 4.29e-01 73.8% 75.3%
6lw5A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 61.0 4.84e-01 99.3% 52.3%
3rzeA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 58.0 4.75e-01 100.0% 50.4%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.66 44.0 4.64e-01 86.2% 74.6%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.66 38.0 4.58e-01 81.4% 86.3%
2z73B01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.66 56.0 4.29e-01 93.1% 71.7%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.66 46.0 5.31e-01 80.7% 100.0%
8hk0C01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.64 47.0 4.71e-01 85.5% 72.7%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.64 41.0 4.16e-01 84.1% 63.9%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.63 42.0 4.84e-01 70.3% 93.2%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.62 45.0 4.66e-01 85.5% 79.0%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.62 43.0 4.79e-01 71.7% 92.0%
2jswA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.61 51.0 4.69e-01 90.3% 96.8%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.60 48.0 3.74e-01 84.1% 82.7%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.59 53.0 4.81e-01 95.9% 97.4%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.59 43.0 3.98e-01 74.5% 74.3%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 51.0 4.21e-01 91.7% 84.7%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 41.0 4.29e-01 89.0% 79.7%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.59 35.0 3.79e-01 82.8% 68.0%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.58 35.0 3.83e-01 87.6% 71.2%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 50.0 4.60e-01 93.8% 93.6%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 46.0 3.78e-01 84.8% 84.9%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 48.0 4.00e-01 92.4% 86.2%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 48.0 3.88e-01 92.4% 87.8%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 44.0 4.60e-01 84.8% 98.5%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.55 40.0 4.13e-01 91.0% 80.9%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.55 41.0 4.40e-01 86.9% 94.2%
4dylA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 44.0 3.73e-01 93.1% 90.0%
5nx5B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 42.0 3.37e-01 88.3% 89.7%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4620542 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.67 61.0 4.67e-01 100.0% 48.1%
3221689 5001.1.1.16 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srt 0.66 60.0 4.72e-01 97.2% 72.3%
3934035 5001.1.1.44 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.64 59.0 4.73e-01 100.0% 53.6%
4660205 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.62 46.0 4.82e-01 76.6% 84.4%
4281434 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.62 42.0 4.41e-01 85.5% 76.2%
3788676 4120.1.1.0 few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP 0.61 36.0 3.74e-01 84.1% 60.7%
3922910 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.61 54.0 4.19e-01 97.2% 68.4%
3471023 164.1.1.15 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › PPPI_inhib 0.61 43.0 4.15e-01 73.1% 65.0%
3867721 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.59 51.0 4.18e-01 90.3% 65.2%
3395959 5086.1.1.166 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PEX11 0.59 38.0 4.52e-01 76.6% 98.9%
3396625 4177.1.1.12 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAM92 0.59 50.0 4.29e-01 91.7% 83.9%
3488934 6157.1.1.1 alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP 0.58 46.0 4.87e-01 83.4% 100.0%
3654353 148.1.3.286 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF29008 0.58 47.0 3.68e-01 86.2% 98.1%
4295958 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 42.0 3.81e-01 82.1% 55.0%
3482602 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.58 49.0 3.99e-01 92.4% 80.4%
3225207 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.57 42.0 4.09e-01 85.5% 67.3%
3591771 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.57 45.0 4.48e-01 94.5% 82.0%
5047411 150.5.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.57 46.0 4.21e-01 87.6% 77.9%
3502455 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.55 47.0 4.10e-01 91.7% 86.7%
3181323 192.29.1.296 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ceramidase 0.54 42.0 4.42e-01 96.6% 89.6%
3920609 150.1.1.31 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety 0.54 45.0 3.74e-01 92.4% 48.7%
3928095 109.4.1.373 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_m 0.51 40.0 2.74e-01 82.8% 40.0%