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Glycoprotein_H

Euk-Vir

Eptesicus_fuscus_gammaherpesvirus

Glycoprotein_H__YP_009552485__Eptesicus_fuscus_gammaherpesvirus__2035399

Identity

Accession:
YP_009552485 ↗
Protein ID:
Glycoprotein_H
Kingdom:
euk

Quality

71.7 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Eptesicus_fuscus_gammaherpesvirus

TaxID: 2035399

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 404-512
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_401700__Human_gammaherpesvirus_4__10376__D360-452
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 43.6 2.30e-11 100.0% 21.0%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3cf6E03 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.73 63.0 5.94e-01 92.7% 95.4%
3gs3A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.72 63.0 4.87e-01 98.2% 53.0%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.70 48.0 4.87e-01 70.6% 87.2%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 51.0 5.40e-01 80.7% 100.0%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.67 49.0 4.06e-01 78.0% 71.6%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 53.0 4.44e-01 87.2% 77.4%
6wb9201 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 51.0 3.82e-01 96.3% 32.5%
2ongA01 1.50.10.130 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain 0.64 51.0 4.22e-01 100.0% 46.6%
4c0eA02 1.25.40.800 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 56.0 4.50e-01 99.1% 57.8%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 42.0 4.48e-01 71.6% 81.7%
2pl2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 49.0 4.09e-01 96.3% 48.5%
4i4cB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.62 51.0 3.50e-01 90.8% 43.7%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.61 45.0 4.69e-01 83.5% 84.0%
2ntxA01 1.20.58.2010 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 0.59 44.0 3.59e-01 78.0% 89.0%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.59 42.0 4.64e-01 72.5% 100.0%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.59 43.0 2.90e-01 75.2% 82.4%
7cc7A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 52.0 4.19e-01 100.0% 51.1%
4ocqA01 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.57 44.0 3.51e-01 83.5% 97.5%
1b8bA00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.57 50.0 3.24e-01 98.2% 33.6%
1a52A00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.56 48.0 3.72e-01 93.6% 84.5%
5jc3A02 1.20.1320.30 Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › 0.56 44.0 4.23e-01 85.3% 96.8%
3qwwA03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 49.0 4.12e-01 100.0% 82.7%
2genA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 45.0 3.84e-01 91.7% 65.4%
3rauA00 1.25.40.280 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains 0.55 47.0 3.40e-01 100.0% 39.4%
1xvpB00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.54 41.0 3.20e-01 79.8% 89.4%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 48.0 4.14e-01 100.0% 69.5%
4n1yB00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.54 47.0 3.71e-01 95.4% 83.3%
3k3uA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.53 37.0 3.49e-01 71.6% 90.5%
2dg7A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 39.0 3.29e-01 77.1% 79.0%
3n00A00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.53 46.0 3.91e-01 97.2% 90.2%
1k90B03 1.20.140.60 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.52 40.0 3.95e-01 82.6% 76.5%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.52 38.0 4.19e-01 85.3% 96.5%
2w0gA00 1.20.58.610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cdc37, Hsp90 binding domain 0.52 42.0 3.97e-01 87.2% 89.9%
2lxlA00 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.51 45.0 4.01e-01 99.1% 90.2%
1k74D00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.51 45.0 3.39e-01 98.2% 83.8%
ECOD (41)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2095478 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.85 79.0 4.95e-01 100.0% 21.0%
2701125 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.83 76.0 4.78e-01 100.0% 21.5%
3188308 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.78 65.0 4.72e-01 89.0% 50.0%
3977220 4121.1.1.1 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.77 53.0 3.97e-01 71.6% 65.0%
5041952 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 60.0 5.61e-01 86.2% 97.8%
4147954 604.34.1.1 ↗ alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB 0.74 54.0 5.86e-01 75.2% 92.2%
3723576 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.73 65.0 4.31e-01 100.0% 31.2%
3872287 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 66.0 4.58e-01 100.0% 43.9%
4013484 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.72 55.0 4.44e-01 79.8% 64.9%
3736151 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.72 66.0 4.18e-01 100.0% 26.3%
3517233 109.4.1.1123 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_PSMD3_N 0.72 58.0 4.16e-01 96.3% 30.3%
3695367 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 64.0 5.25e-01 100.0% 68.3%
3690171 3924.1.1.0 ↗ alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 0.70 52.0 4.27e-01 78.9% 47.5%
3720243 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 60.0 4.59e-01 99.1% 63.8%
4048326 3924.1.1.1 ↗ alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Fungal_trans_2 0.68 56.0 4.34e-01 90.8% 72.2%
4048456 604.34.1.1 ↗ alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB 0.67 52.0 5.72e-01 97.2% 98.9%
3613828 109.54.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 0.66 56.0 4.89e-01 99.1% 61.0%
3598737 5000.4.1.0 ↗ alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain 0.66 56.0 4.76e-01 92.7% 76.7%
3511211 109.4.1.509 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRP12_HEAT 0.66 59.0 3.74e-01 100.0% 20.2%
4510201 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 56.0 4.00e-01 96.3% 32.6%
3739750 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 57.0 4.16e-01 99.1% 35.5%
3497921 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 54.0 3.48e-01 96.3% 22.9%
4015749 109.7.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E 0.63 44.0 5.02e-01 87.2% 100.0%
3457370 109.4.1.112 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Xpo1 0.62 55.0 3.89e-01 100.0% 34.4%
3831202 109.4.1.191 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7 0.61 53.0 3.65e-01 99.1% 27.4%
4994869 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 54.0 5.24e-01 99.1% 90.8%
5059963 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.61 51.0 4.75e-01 95.4% 92.4%
None — 0.60 52.0 4.16e-01 99.1% 47.2%
3283672 4121.1.1.1 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.59 52.0 3.97e-01 100.0% 81.9%
3466631 109.4.1.1529 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3_p135, TPR_12 0.59 46.0 3.03e-01 86.2% 18.4%
3351948 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 50.0 4.50e-01 99.1% 68.7%
3682606 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.58 49.0 2.99e-01 100.0% 14.4%
4007651 6055.1.1.24 ↗ extended segments › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › Preprotein translocase subunit YajC › DUF1422 0.58 36.0 4.11e-01 73.4% 85.0%
None — 0.57 50.0 3.10e-01 100.0% 64.7%
3696407 4121.1.1.7 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF26616 0.56 50.0 3.93e-01 100.0% 81.7%
3729571 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 48.0 4.38e-01 94.5% 88.3%
3258025 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.53 39.0 2.98e-01 77.1% 70.8%
5018283 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.53 41.0 4.24e-01 83.5% 91.0%
3227192 188.1.1.1 ↗ alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.51 43.0 3.23e-01 93.6% 76.8%
3926776 3930.1.1.0 ↗ alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.51 40.0 3.77e-01 85.3% 68.9%
4975727 186.1.1.0 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.50 41.0 4.22e-01 100.0% 92.4%
D2 medium residues 101-123_178-314
PDB
D3 medium residues 124-144_159-177_315-399
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.86 81.0 5.81e-01 100.0% 79.7%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 51.0 5.73e-01 92.8% 91.8%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.73 50.0 4.95e-01 70.4% 75.9%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 35.0 4.48e-01 72.0% 78.9%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.71 46.0 4.39e-01 92.8% 55.8%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.71 36.0 4.54e-01 72.0% 81.3%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 37.0 4.80e-01 72.8% 89.0%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 51.0 5.56e-01 92.0% 90.3%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.70 45.0 4.49e-01 92.0% 63.5%
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 36.0 3.79e-01 91.2% 55.0%
4g1tA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 38.0 3.88e-01 98.4% 54.5%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 49.0 5.50e-01 92.0% 95.9%
2fb5A01 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.67 36.0 4.71e-01 72.0% 93.1%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 46.0 4.85e-01 93.6% 80.9%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.65 35.0 3.71e-01 72.0% 57.1%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 36.0 4.39e-01 72.0% 85.7%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 51.0 5.35e-01 92.8% 90.2%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.65 35.0 4.16e-01 73.6% 75.6%
2wdqA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.64 47.0 4.84e-01 80.8% 79.5%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.64 33.0 3.76e-01 71.2% 64.2%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 47.0 5.00e-01 92.0% 88.7%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 50.0 5.39e-01 94.4% 100.0%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 35.0 4.18e-01 72.8% 82.7%
3evyA00 1.20.58.910 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 40.0 4.66e-01 95.2% 95.2%
3cbuA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 44.0 4.37e-01 95.2% 70.1%
4g80T00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.59 43.0 4.18e-01 96.8% 67.6%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.59 48.0 4.85e-01 88.0% 85.8%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 53.0 4.35e-01 96.8% 79.3%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 44.0 4.48e-01 86.4% 80.3%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.58 43.0 3.17e-01 76.8% 86.5%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 45.0 4.95e-01 88.0% 100.0%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 44.0 4.73e-01 94.4% 95.3%
4oe8C00 1.10.8.1170 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.56 37.0 4.40e-01 74.4% 97.7%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 50.0 4.23e-01 100.0% 63.4%
4qndA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.54 40.0 4.41e-01 96.8% 97.9%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.53 45.0 4.08e-01 92.0% 73.4%
4iggB06 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 42.0 3.51e-01 84.8% 88.4%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.52 36.0 4.10e-01 72.0% 97.9%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 36.0 2.99e-01 72.0% 63.3%
4rg9B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 31.0 2.83e-01 99.2% 44.9%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.50 37.0 3.31e-01 75.2% 79.2%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3598538 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.79 38.0 5.35e-01 90.4% 92.3%
3497418 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.76 53.0 5.92e-01 92.0% 89.0%
3607831 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.74 53.0 5.83e-01 93.6% 92.0%
4941262 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.73 48.0 5.27e-01 92.8% 80.6%
4016578 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 52.0 5.60e-01 94.4% 87.6%
3770274 603.1.1.198 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF4716 0.72 51.0 5.82e-01 92.8% 96.8%
3577937 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 53.0 5.49e-01 92.0% 82.6%
3593236 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 48.0 5.14e-01 93.6% 78.2%
3265125 604.22.1.1 ↗ alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N 0.71 49.0 4.97e-01 92.8% 70.4%
3923984 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.71 50.0 5.70e-01 88.8% 95.8%
4177674 4992.1.1.23 ↗ extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N 0.71 38.0 4.06e-01 72.8% 59.1%
3784566 604.1.1.191 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29057 0.71 54.0 6.02e-01 94.4% 100.0%
4206524 605.2.1.3 ↗ alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N 0.70 37.0 3.98e-01 72.8% 58.2%
4079591 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.70 37.0 3.98e-01 72.8% 58.2%
3254719 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.70 49.0 5.58e-01 93.6% 95.8%
4959083 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.69 47.0 4.19e-01 91.2% 50.0%
3240455 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 47.0 5.43e-01 93.6% 97.8%
3799931 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.68 47.0 5.08e-01 92.8% 84.8%
3418815 3755.3.1.366 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7653 0.68 37.0 3.74e-01 71.2% 53.6%
3619724 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.66 46.0 5.09e-01 93.6% 89.0%
3321745 601.1.1.105 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › RPW8 0.66 42.0 4.21e-01 94.4% 63.2%
4331100 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.66 45.0 5.07e-01 92.0% 92.6%
3240438 3684.1.1.30 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF29678 0.64 46.0 4.30e-01 94.4% 59.4%
3479092 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.64 46.0 5.06e-01 93.6% 93.0%
4025809 604.6.1.22 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 0.63 48.0 5.12e-01 88.8% 90.9%
3940580 604.6.1.14 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › RasGAP_C 0.63 45.0 4.74e-01 92.0% 81.7%
3217606 192.29.1.172 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 0.62 45.0 3.99e-01 93.6% 51.7%
3523206 3826.1.1.20 ↗ alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › MYO6_lever 0.62 42.0 4.50e-01 81.6% 79.1%
3169342 109.4.1.381 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rrn11 0.60 52.0 4.21e-01 99.2% 51.1%
3973206 150.5.1.126 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › HisKA 0.60 38.0 4.29e-01 72.8% 84.2%
3934654 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 49.0 4.32e-01 88.8% 97.8%
3829132 604.3.1.35 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF6857 0.59 51.0 4.80e-01 90.4% 82.8%
3207391 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.58 38.0 3.59e-01 76.0% 56.6%
3837882 150.1.1.196 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF27018 0.56 43.0 4.12e-01 94.4% 69.7%
4340169 601.3.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.56 39.0 4.02e-01 72.0% 95.1%
3259417 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.56 51.0 4.32e-01 97.6% 79.5%
3784873 633.23.1.9 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › SUR7 0.56 48.0 4.25e-01 92.8% 81.7%
3940375 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.54 46.0 4.04e-01 90.4% 78.9%
3519661 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.54 40.0 4.28e-01 85.6% 90.0%
3268032 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.53 38.0 3.90e-01 92.0% 75.8%
3996900 601.25.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain 0.53 39.0 3.87e-01 85.6% 72.3%
54304 633.15.1.0 ↗ alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N 0.53 42.0 3.83e-01 93.6% 64.0%
3680328 633.6.1.0 ↗ alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like 0.52 41.0 3.99e-01 83.2% 78.6%
4994917 3834.1.1.25 ↗ alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.52 37.0 2.91e-01 72.8% 80.8%
3267624 192.29.1.19 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.51 42.0 4.14e-01 91.2% 82.2%
3692987 3755.3.1.481 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF30554 0.51 36.0 3.12e-01 72.8% 85.3%
3832044 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.51 39.0 4.05e-01 80.0% 94.8%
3506760 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 36.0 3.57e-01 72.8% 83.1%
D4 medium residues 516-595
PDB
Domain cluster: rep: envelope_glycoprotein_H__NP_042618__Equid_gammaherpesvirus_2__12657__D496-575
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 62.6 4.10e-17 88.8% 13.6%
D5 medium residues 596-652_669-750
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 164.5 1.70e-48 100.0% 97.9%