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Guanylate_kinase

Euk-Vir

Mollivirus_sibericum_Viruses.

Guanylate_kinase__YP_009165069__Mollivirus_sibericum_Viruses.__X

Identity

Accession:
YP_009165069 ↗
Protein ID:
Guanylate_kinase
Kingdom:
euk

Quality

71.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-113
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00625.28 best Guanylate_kin 63.6 2.90e-17 86.7% 52.8%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kgdA02 3.30.63.10 Alpha Beta › 2-Layer Sandwich › Guanylate Kinase phosphate binding domain › Guanylate Kinase phosphate binding domain 0.87 46.0 6.40e-01 79.6% 100.0%
4wsiB03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 62.0 5.12e-01 100.0% 57.9%
3wp0A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 61.0 5.14e-01 100.0% 63.0%
6nuiA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 59.0 4.93e-01 98.2% 60.4%
3crvA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 55.0 4.58e-01 100.0% 95.9%
7jt8I02 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.59 52.0 4.81e-01 97.3% 96.5%
1p3dA03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.57 51.0 4.67e-01 100.0% 92.0%
1ucrB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 32.0 3.78e-01 77.0% 81.3%
8kcaB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 50.0 4.41e-01 99.1% 88.3%
1yzyA02 3.40.980.20 Alpha Beta › 3-Layer(aba) Sandwich › Molybdenum Cofactor Biosythetic Enzyme; Chain A › Four-carbon acid sugar kinase, nucleotide binding domain 0.56 47.0 4.07e-01 100.0% 57.9%
2b8tA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 51.0 4.74e-01 100.0% 97.1%
3zl8A03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.56 50.0 4.68e-01 100.0% 87.8%
2p6rA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 49.0 4.15e-01 99.1% 79.9%
7lgnB03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.56 49.0 4.63e-01 100.0% 97.1%
6bogA05 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 48.0 3.99e-01 99.1% 97.6%
3nklB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 41.0 4.03e-01 99.1% 73.2%
6x50A03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 48.0 3.93e-01 100.0% 93.3%
3eozB01 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.53 46.0 4.16e-01 100.0% 95.1%
1xmxA03 1.10.10.680 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Hypothetical protein VC1899 (Restriction endonuclease-like) 0.52 33.0 3.65e-01 91.2% 80.9%
2gzaB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 45.0 3.71e-01 99.1% 63.8%
5xyiK00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 33.0 3.64e-01 75.2% 82.2%
3mczA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 42.0 3.33e-01 92.0% 69.5%
2qbyA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.50 45.0 3.94e-01 99.1% 80.3%
ECOD (74)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3588701 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.91 84.0 6.97e-01 100.0% 60.6%
4213537 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.90 86.0 7.02e-01 100.0% 60.5%
4188216 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.89 84.0 6.71e-01 100.0% 55.6%
4364445 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.88 83.0 6.47e-01 100.0% 50.9%
4515833 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.88 84.0 6.48e-01 100.0% 50.2%
3965925 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.88 84.0 6.72e-01 100.0% 56.5%
3593771 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.88 84.0 6.49e-01 100.0% 63.7%
4678860 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.88 84.0 6.79e-01 100.0% 58.8%
165134 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.88 83.0 6.76e-01 100.0% 59.2%
4296001 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.88 83.0 6.70e-01 100.0% 59.0%
3613625 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.88 83.0 6.38e-01 100.0% 60.4%
3712406 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.87 83.0 6.59e-01 100.0% 57.1%
3910006 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.87 82.0 6.39e-01 100.0% 64.1%
4461479 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.87 82.0 6.77e-01 100.0% 61.1%
4114056 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.86 81.0 6.64e-01 100.0% 58.8%
4660772 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.86 81.0 6.39e-01 100.0% 55.8%
4239688 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.86 81.0 6.44e-01 100.0% 55.2%
3599128 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.86 81.0 6.61e-01 100.0% 60.5%
3706135 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.86 81.0 6.48e-01 100.0% 62.0%
2393040 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.85 81.0 6.35e-01 100.0% 54.6%
3779005 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.85 80.0 4.99e-01 100.0% 21.6%
3920323 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.85 80.0 6.01e-01 100.0% 46.7%
3479738 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.85 80.0 4.86e-01 100.0% 19.5%
1537619 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.85 74.0 6.14e-01 100.0% 56.1%
3485807 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.84 79.0 6.04e-01 100.0% 49.2%
3447908 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.84 78.0 6.29e-01 100.0% 56.1%
4232099 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.83 78.0 6.12e-01 100.0% 51.8%
4256195 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.83 75.0 6.30e-01 100.0% 60.6%
4061553 2004.1.1.208 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_33 0.83 76.0 6.39e-01 100.0% 61.7%
4062874 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.83 76.0 6.26e-01 100.0% 58.4%
5063684 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.82 77.0 5.91e-01 100.0% 47.3%
3960806 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.82 75.0 6.58e-01 97.3% 70.6%
4269138 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.82 76.0 6.31e-01 100.0% 59.5%
4297700 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.82 74.0 6.17e-01 100.0% 58.9%
4510425 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.82 76.0 6.37e-01 100.0% 62.2%
4477375 2004.1.1.192 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 0.81 74.0 6.14e-01 100.0% 58.2%
4012507 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.81 75.0 6.24e-01 100.0% 63.2%
3193192 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.81 76.0 6.16e-01 100.0% 62.5%
5050242 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.81 76.0 6.20e-01 100.0% 58.2%
None 0.81 75.0 6.07e-01 100.0% 55.1%
4055310 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.81 73.0 6.10e-01 100.0% 58.5%
4321081 2004.1.1.192 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 0.81 73.0 6.15e-01 97.3% 60.6%
4483715 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.81 74.0 6.24e-01 100.0% 61.7%
3481390 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.80 74.0 5.90e-01 100.0% 54.0%
4354223 2004.1.1.192 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_18 0.79 74.0 6.16e-01 100.0% 61.1%
4098754 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.79 73.0 6.02e-01 100.0% 60.5%
4305751 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.76 69.0 5.76e-01 100.0% 59.0%
4190166 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.75 69.0 5.66e-01 100.0% 57.0%
3798335 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.74 68.0 5.60e-01 100.0% 58.0%
3931844 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.74 67.0 5.65e-01 100.0% 60.5%
4002879 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.74 59.0 4.95e-01 100.0% 50.5%
3389805 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.73 66.0 5.22e-01 100.0% 48.9%
3580834 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.73 67.0 5.51e-01 100.0% 58.0%
3519997 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.73 67.0 5.50e-01 100.0% 58.0%
3482144 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.72 65.0 5.33e-01 100.0% 54.8%
4269513 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.71 65.0 5.08e-01 100.0% 49.4%
3492473 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.70 64.0 5.89e-01 100.0% 97.2%
3481198 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 62.0 4.95e-01 100.0% 48.3%
3789700 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 64.0 5.33e-01 100.0% 59.5%
3397637 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.69 63.0 4.96e-01 100.0% 49.4%
3524949 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.69 57.0 4.77e-01 100.0% 53.0%
3798314 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.69 63.0 5.01e-01 100.0% 51.1%
3623496 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.69 64.0 5.18e-01 100.0% 56.6%
3539257 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.69 63.0 5.11e-01 100.0% 55.2%
3894021 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.69 62.0 5.00e-01 100.0% 52.7%
3798014 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.69 63.0 4.92e-01 100.0% 49.4%
3230470 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.68 61.0 5.03e-01 100.0% 55.6%
3474707 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.68 62.0 5.08e-01 100.0% 55.6%
3543629 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.61 55.0 4.69e-01 100.0% 93.0%
3235084 4244.1.1.5 a/b three-layered sandwiches › EreA/ChaN-like › EreA/ChaN-like › EreA/ChaN-like › TraB_PrgY_gumN 0.60 53.0 4.08e-01 99.1% 83.0%
4610850 2004.1.1.30 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.57 50.0 4.22e-01 100.0% 76.5%
3436096 2004.1.1.364 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C 0.53 47.0 3.05e-01 99.1% 51.9%
2106037 101.1.2.47 alpha arrays › HTH › HTH › winged helix domain › S10_plectin 0.51 33.0 3.64e-01 75.2% 82.2%
3536880 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.51 36.0 2.62e-01 73.5% 33.8%
D2 medium residues 114-227
PDB