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HC-Pro

Euk-Vir

Donkey_orchid_virus_A

HC-Pro__YP_007969885__Donkey_orchid_virus_A__1198144

Identity

Accession:
YP_007969885 ↗
Protein ID:
HC-Pro
Kingdom:
euk

Quality

78.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 373-561
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00851.25 best Peptidase_C6 231.8 2.20e-68 99.5% 41.4%
D2 medium residues 24-108
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00851.25 best Peptidase_C6 52.0 7.80e-14 100.0% 18.6%
CATH (52)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.74 49.0 5.19e-01 84.7% 76.0%
2hydA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.74 51.0 3.43e-01 71.8% 86.7%
3ceqA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.74 50.0 3.47e-01 83.5% 23.2%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.74 49.0 5.10e-01 84.7% 73.4%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.73 50.0 5.06e-01 88.2% 72.3%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 62.0 5.03e-01 95.3% 91.7%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 59.0 4.80e-01 94.1% 93.7%
2pqrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 44.0 4.29e-01 84.7% 59.1%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 57.0 4.75e-01 91.8% 96.0%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 57.0 4.60e-01 95.3% 86.0%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 50.0 4.33e-01 88.2% 52.3%
4pxoA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 56.0 4.85e-01 94.1% 74.0%
2ikbC00 1.20.141.10 Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1 0.65 56.0 4.65e-01 100.0% 88.8%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 55.0 4.99e-01 96.5% 74.1%
2v6kA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 55.0 4.73e-01 94.1% 74.6%
4a25B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 53.0 4.41e-01 96.5% 86.3%
3nivC02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 53.0 4.73e-01 94.1% 78.2%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.62 48.0 4.63e-01 94.1% 71.7%
1gt0D00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.61 44.0 4.54e-01 75.3% 91.1%
1dk8A02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.61 43.0 4.38e-01 87.1% 75.3%
1ivhA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 49.0 4.16e-01 89.4% 78.7%
3n71A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 54.0 4.01e-01 100.0% 40.4%
4c9bB00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 41.0 2.86e-01 88.2% 21.7%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 42.0 4.42e-01 80.0% 85.1%
4p4tA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 43.0 2.93e-01 77.6% 91.6%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 50.0 4.73e-01 91.8% 96.0%
3wirA02 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.59 47.0 3.08e-01 88.2% 36.8%
1nigA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.58 48.0 4.03e-01 90.6% 95.2%
3lomA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 51.0 3.61e-01 100.0% 96.5%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 47.0 4.38e-01 88.2% 86.0%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 46.0 4.29e-01 88.2% 88.1%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 45.0 4.24e-01 87.1% 89.0%
3n00A00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.58 42.0 3.30e-01 85.9% 35.9%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 48.0 4.51e-01 90.6% 94.1%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.58 48.0 4.35e-01 91.8% 82.5%
4nuuB02 1.20.58.830 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 48.0 4.26e-01 92.9% 95.1%
3q9oA02 3.90.1350.10 Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain 0.57 41.0 3.40e-01 77.6% 74.3%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.57 49.0 4.47e-01 97.6% 80.5%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 47.0 4.43e-01 91.8% 88.7%
2juaA00 1.20.1480.30 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein 0.56 49.0 4.61e-01 96.5% 80.4%
2cz2A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 46.0 4.15e-01 94.1% 68.3%
3ab3D00 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.56 42.0 3.41e-01 80.0% 80.6%
4u72A01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 43.0 3.20e-01 84.7% 87.8%
7ccmB01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.55 43.0 3.65e-01 84.7% 60.1%
4xxiA00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.55 48.0 4.06e-01 100.0% 99.3%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.54 47.0 4.55e-01 100.0% 84.8%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.54 46.0 3.95e-01 95.3% 72.7%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.53 39.0 3.90e-01 91.8% 76.1%
2vixA03 1.20.1280.240 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.53 43.0 4.04e-01 95.3% 92.9%
3wd6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 44.0 3.99e-01 94.1% 72.9%
2b6cA01 1.20.1660.10 Mainly Alpha › Up-down Bundle › ARM repeat fold › Hypothetical protein (EF3068) 0.52 44.0 4.01e-01 96.5% 88.8%
4uurA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 43.0 3.92e-01 98.8% 100.0%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3726818 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 52.0 4.23e-01 83.5% 38.7%
3529996 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.69 49.0 3.74e-01 84.7% 33.2%
3465231 192.15.1.189 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Frigida 0.68 56.0 5.77e-01 88.2% 92.5%
5034573 4156.1.1.6 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Helicase_dom4_arc 0.68 55.0 4.57e-01 87.1% 93.1%
7430 235.1.1.13 a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like › Glyco_hydro_108,PG_binding_3 0.66 58.0 4.76e-01 100.0% 89.0%
3411668 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.65 46.0 4.80e-01 85.9% 82.7%
3985371 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.65 56.0 3.97e-01 91.8% 38.3%
3200625 109.4.1.158 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C 0.64 42.0 2.88e-01 89.4% 18.1%
4883406 622.4.1.1 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 0.63 54.0 4.80e-01 90.6% 84.5%
3372307 109.4.1.67 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RINT1_TIP1 0.63 54.0 3.11e-01 92.9% 13.9%
5056432 607.1.1.0 alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 0.63 44.0 3.87e-01 76.5% 49.6%
None 0.63 55.0 4.19e-01 100.0% 74.6%
3640330 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 54.0 4.60e-01 96.5% 88.6%
3916833 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.61 44.0 4.55e-01 75.3% 92.5%
3367300 101.1.10.7 alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.61 47.0 3.79e-01 81.2% 67.5%
3240658 109.4.1.409 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm,IBB,Arm_3 0.61 42.0 3.02e-01 88.2% 23.5%
3389546 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.60 47.0 4.83e-01 84.7% 88.7%
3368223 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 50.0 3.70e-01 90.6% 54.9%
4128901 109.4.1.158 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C 0.60 39.0 2.76e-01 84.7% 20.7%
4485359 103.2.1.0 alpha arrays › RuvA-C › ATP cone › ATP cone 0.60 40.0 3.88e-01 92.9% 61.1%
3497641 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.60 47.0 4.44e-01 83.5% 91.0%
2134378 11.1.1.153 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ERAP1_C 0.59 41.0 4.15e-01 71.8% 77.6%
3742209 6140.1.1.0 alpha superhelices › Cdc45-Binding Domain in Sld3/Treslin › Cdc45-Binding Domain in Sld3/Treslin › Cdc45-Binding Domain in Sld3/Treslin 0.59 45.0 3.34e-01 83.5% 87.2%
3784566 604.1.1.191 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29057 0.58 45.0 4.27e-01 82.4% 83.0%
3243599 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.58 47.0 4.33e-01 91.8% 76.5%
4026662 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.57 47.0 4.04e-01 91.8% 59.3%
3271444 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 48.0 3.43e-01 95.3% 41.8%
5019542 622.4.1.67 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518 0.57 45.0 4.30e-01 87.1% 86.9%
3427778 604.1.1.144 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26575 0.56 46.0 4.75e-01 89.4% 100.0%
3965294 3558.1.1.0 alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain 0.56 43.0 4.16e-01 80.0% 77.9%
4122005 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.54 44.0 3.41e-01 90.6% 58.0%
3478148 109.4.1.632 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MMS22L_C 0.54 45.0 2.98e-01 92.9% 31.3%
3326044 192.15.1.1 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28 0.54 44.0 4.09e-01 90.6% 80.0%
3999236 622.1.1.1 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C 0.53 46.0 4.36e-01 100.0% 81.0%
3168872 192.15.1.1 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28 0.52 42.0 3.96e-01 91.8% 84.8%
D3 medium residues 113-190
PDB
D4 medium residues 191-293
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00851.25 best Peptidase_C6 31.3 1.60e-07 88.3% 16.4%
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1w9rA00 1.20.58.440 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A 0.60 45.0 4.35e-01 80.6% 90.8%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.58 44.0 4.00e-01 80.6% 72.0%
2uuiA00 1.20.120.550 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Membrane associated eicosanoid/glutathione metabolism-like domain 0.57 43.0 3.76e-01 80.6% 63.9%
4mu9B00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.56 40.0 2.73e-01 72.8% 60.7%
1kn1B00 1.10.490.20 Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins 0.55 38.0 3.34e-01 70.9% 70.2%
4ozvA00 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.54 38.0 2.72e-01 74.8% 65.8%
3jsbA01 1.20.1440.300 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain 0.51 31.0 3.45e-01 75.7% 75.3%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3188674 109.4.1.681 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.68 49.0 3.21e-01 74.8% 21.2%
3387293 601.46.1.1 alpha bundles › Four-helical up-and-down bundle › Regulatory CZB domain of diguanylate cyclase YdeH › Regulatory CZB domain of diguanylate cyclase YdeH › CZB 0.59 41.0 4.02e-01 70.9% 81.8%
3542442 5038.2.1.1 alpha superhelices › Cytochrome c oxidase subunit I-like › MAPEG domain-like › MAPEG domain-like › MAPEG 0.54 44.0 4.05e-01 91.3% 77.9%
3831657 145.1.1.58 alpha arrays › F-box domain › F-box domain › F-box domain › Chloroplast_duf 0.53 41.0 3.59e-01 81.6% 74.2%